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David Tamborero, PhD
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Journal Articles

Midostaurin Shows Efficacy in Refractory Multiple Myeloma with TP53 Mutation and Elevated Expression of NTRK1, NTRK3 and AURKA

Muntasir M Majumder, MSc, BPharm, David Tamborero, PhD, Pekka Anttila, Raija Helena Silvennoinen, MD, Samuli Eldfors, MSc, Juha Lievonen, Ashwini Kumar, MRes, Alun Parsons, Minna Suvela, MSC, Esa Jantunen, Kimmo Porkka, MD PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4412.
https://doi.org/10.1182/blood.V130.Suppl_1.4412.4412
Published: 2017
Journal Articles

Integrating Genomic Alterations in Diffuse Large B-Cell Lymphoma Identifies New Relevant Pathways and Potential Therapeutic Targets

Ivan Dlouhy, MD, Kennosuke Karube, MDPhD, Anna Enjuanes, David Martín-García, Ferran Nadeu, Gonzalo R Ordoñez, Jordina Rovira, Cristina Royo, Alba Navarro, Blanca Gonzalez, Giancarlo Castellano, Carlota Rubio-Perez, David Tamborero, PhD, Javier Briones, PhD MD, Antonio Salar, MD PhD, Juan-Manuel Sancho, Santiago Mercadal, Eva Gonzalez Barca, PhD, Lourdes Escoda, MD PhD, Miyoshi Hiroaki, MD PhD, Koichi Ohshima, MD PhD, Koji Kato, MD PhD, Koichi Akashi, MD PhD, Anna Mozos, Lluis Colomo, MD PhD, Miguel Alcoceba, BSc, PhD, Alexandra Valera, Anna Carrio, Nuria Lopez-Bigas, Roland Schmitz, PhD, Louis Staudt, MD PhD, Pedro Jares, Itziar Salaverria, Armando López-Guillermo, Elias Campo, MD PhD
Journal: Blood
Blood (2016) 128 (22): 152.
https://doi.org/10.1182/blood.V128.22.152.152
Published: 2016
Journal Articles

Analysis of Clonal Evolution in Chronic Lymphocytic Leukemia from Inactive to Symptomatic Disease Prior Treatment Using Whole-Exome Sequencing

María Hernández-Sánchez, Lenka Radova, PhD, Jana Kotaskova, David Tamborero, PhD, Ana E Rodriguez, PhD, Karla Plevova, PhD, María Abáigar, PhD, Vasileios Bikos, Rocío Benito, PhD, Sylvia Takacova, PhD, Miguel Quijada, Ana África Martín, MD, Miguel Alcoceba, BSc, PhD, Alfonso García de Coca, Michael Doubek, Marcos González, MD PhD, Nuria Lopez-Bigas, PhD, Sarka Pospisilova, Jesús María Hernández-Rivas, MD
Journal: Blood
Blood (2016) 128 (22): 3206.
https://doi.org/10.1182/blood.V128.22.3206.3206
Published: 2016
Journal Articles

DNA Damage Repair Pathway Alterations in Multiple Myeloma Predict Poor Prognosis, but Correlate with Sensitivity to IGF1R-PI3K-mTOR and HDAC Inhibitors

Muntasir M Majumder, MSc, MPharm, David Tamborero, PhD, Pekka Anttila, MD, Raija Silvennoinen, MD, Samuli Eldfors, MSc, Ashwini Kumar, MSc, Juha Lievonen, MD, Alun Parsons, MSc, Minna Suvela, Esa Jantunen, MD PhD, Kimmo Porkka, MD PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2016) 128 (22): 198.
https://doi.org/10.1182/blood.V128.22.198.198
Published: 2016
Journal Articles

Patterns of Clonal Evolution Assessed By Whole Exome Sequencing during Progression from MDS to AML Are Related to Therapy

María Abáigar, PhD, Jesús M Hernández-Sánchez, David Tamborero, PhD, Marta Martín-Izquierdo, María Díez-Campelo, MD, María Hernández-Sánchez, Fernando Ramos, MD, Marta Megido, Carlos Aguilar, Eva Lumbreras, Isabel Recio, Carmen Olivier, Cristina Robledo, Rocío Benito, PhD, Nuria Lopez-Bigas, Consuelo Del Cañizo, MD PhD, Jesús María Hernández-Rivas, MD
Journal: Blood
Blood (2016) 128 (22): 4309.
https://doi.org/10.1182/blood.V128.22.4309.4309
Published: 2016
Journal Articles

Stratification of Multiple Myeloma Patients Based on Ex Vivo Drug Sensitivity and Identification of New Treatments for Patients with High-Risk Relapsed/Refractory Disease

Muntasir Mamun Majumder, MSc,MPharm, Raija Silvennoinen, MD, Pekka Anttila, MD, David Tamborero, PhD, Samuli Eldfors, MSc, Juha Lievonen, MD, Riikka J Karjalainen, Heikki Kuusanmäki, MSc, Alun Parsons, Minna Suvela, Kimmo Porkka, MD PhD, Caroline Heckman
Journal: Blood
Blood (2015) 126 (23): 3006.
https://doi.org/10.1182/blood.V126.23.3006.3006
Published: 2015
Journal Articles

Landscape of Driver Lesions in Multiple Myeloma and Consequences for Targeted Drug Response

David Tamborero, PhD, Muntasir Mamun Majumder, MSc,BPharm, Raija Silvennoinen, MD, Samuli Eldfors, MSc, Pekka Anttila, MD, Juha Lievonen, MD, Alun Parsons, MSc, Minna Suvela, BSc, Marjanna Säily, Kimmo Porkka, MD PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2014) 124 (21): 3351.
https://doi.org/10.1182/blood.V124.21.3351.3351
Published: 2014
Journal Articles

Stroma-Derived Factors Significantly Impact the Drug Response Profiles of Patient-Derived Primary AML Cells: Implications for Drug Sensitivity Testing

Riikka Karjalainen, MSc, Tea Pemovska, MSc, Muntasir Mamun Majumder, MSc, David Tamborero, PhD, Bhagwan Yadav, MSc, Mika Kontro, MD, Bjørn Gjertsen, MD PhD, Alun Parsons, MSc, Minna Suvela, BSc, Tero Aittokallio, PhD, Kimmo Porkka, MD PhD, Olli Kallioniemi, MD PhD, Krister Wennerberg, PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2014) 124 (21): 3505.
https://doi.org/10.1182/blood.V124.21.3505.3505
Published: 2014
Journal Articles

Identification of Dual PI3K/mTOR and BCL2 Inhibitors for the Treatment of High Risk Multiple Myeloma

Raija Silvennoinen, MD, Muntasir Mamun Majumder, MSc,BPharm, David Tamborero, PhD, Pekka Anttila, MD, Samuli Eldfors, MSc, Riikka Karjalainen, MSc, Heikki Kuusanmäki, MSc, Juha Lievonen, MD, Alun Parsons, MSc, Minna Suvela, Marjaana Säily, MDPhD, Kimmo Porkka, MD PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2014) 124 (21): 646.
https://doi.org/10.1182/blood.V124.21.646.646
Published: 2014