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Journal Articles

Pre-CAR Blinatumomab Is Associated with Increased Post-CD19 CAR Relapse and Decreased Event Free Survival

Agne Taraseviciute, MD, Seth M. Steinberg, PhD, Regina M. Myers, MD, Lia Gore, MD, Adam J. Lamble, MD, Patrick A. Brown, MD, Jennifer Sheppard, Bonnie Yates, NP, Perry Chung, MD, Lee Chen, Colleen Annesley, MD, Deepa Bhojwani, MD, Theodore W. Laetsch, MD, Rebecca A Gardner, MD, Susan R. Rheingold, MD, Michael A Pulsipher, MD, Nirali N. Shah, MD

Blood (2020) 136 (Supplement 1): 13–14.

https://doi.org/10.1182/blood-2020-139260

Published: 2020

Journal Articles

Cortical Thinning and Neuropsychologic Measures Predict CD19 CAR T Cell Therapy-Associated Neurotoxicity

Agne Taraseviciute, MD, Deepa Bhojwani, MD, Ravi Bansal, PhD, Bradley S Peterson, MD, Michael A Pulsipher, MD, Alan S. Wayne, MD, Courtney Allem, Michael Sheard, PhD, Joey Trampush, PhD

Blood (2020) 136 (Supplement 1): 26–27.

https://doi.org/10.1182/blood-2020-142609

Published: 2020

Journal Articles

Targeting of Integrin α4/VCAM-1 with AVA4746 Modulates the Redox-Status and Metabolism in ALL and Angiogenesis

Ruan Yongsheng, MD, Enzi Jiang, MD PhD, Hye Na Kim, Heather Ogana, Mo Yang, MD, Deepa Bhojwani, MD, Alan S. Wayne, MD, Yong-Mi Kim, MD MPH, PhD

Blood (2019) 134 (Supplement_1): 3881.

https://doi.org/10.1182/blood-2019-132101

Published: 2019

Journal Articles

Cell Adhesion of ALL to Stromal Cells May Mediate CAR T-Cell Resistance: A Novel Escape Mechanism for Immunotherapy

Hye Na Kim, Enzi Jiang, MD PhD, Ruan Yongsheng, MD, Heather Ogana, Nour Abdel-Azim, Justin Le, BS, Annie Luong, Halvard Bonig, MD, Nabil Ahmed, MD, Moghimi Babak, MD, Michael A. Pulsipher, MD, Deepa Bhojwani, MD, Alan S. Wayne, MD, Chintan Parekh, MBBS, Hisham Abdel-Azim, Nora Heisterkamp, Yong-Mi Kim, MD MPH, PhD

Blood (2019) 134 (Supplement_1): 2623.

https://doi.org/10.1182/blood-2019-132131

Published: 2019

Journal Articles

Immunologic and Brain Bases of Neurotoxicity Associated with CAR T-Cell Therapy

Deepa Bhojwani, MD, Bradley Peterson, MD, Agne Taraseviciute, MD PhD, Michael A. Pulsipher, MD, Alan S. Wayne, MD, Michael Sheard, PhD, Courtney Allem, Joey Trampush, PhD, Ravi Bansal, PhD

Blood (2019) 134 (Supplement_1): 1946.

https://doi.org/10.1182/blood-2019-127533

Published: 2019

Journal Articles

Phase 1 Study of Decitabine and Vorinostat Followed By Fludarabine, Cytarabine and G-CSF (FLAG) in Children, Adolescents and Young Adults with Relapsed/Refractory AML: Report from the Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL) Consortium

Lauren Pommert, MDMS, Deepa Bhojwani, MD, Richard Sposto, PhD, Ellynore Florendo, Eric Schafer, MD, Nathan Gossai, MD, Van Thu Huynh, MD, Sridhar Rao, MD PhD, Michael J. Burke, MD

Blood (2019) 134 (Supplement_1): 1325.

https://doi.org/10.1182/blood-2019-127298

Published: 2019

Journal Articles

A Phase 2 Trial of Inotuzumab Ozogamicin (InO) in Children and Young Adults with Relapsed or Refractory (R/R) CD22+ B-Acute Lymphoblastic Leukemia (B-ALL): Results from Children's Oncology Group Protocol AALL1621

Maureen M O'Brien, MD, Lingyun Ji, PhD, Nirali N. Shah, MD, Susan R. Rheingold, MD, Deepa Bhojwani, MD, Joanna S. Yi, MD, Constance M. Yuan, MD PhD, Andrew C Harris, MD, Patrick A. Brown, MD, Michael J. Borowitz, MD PhD, Olga Militano, PharmD, Meenakshi Devidas, PhD, Elizabeth A. Raetz, MD, Lia Gore, MD, Mignon L. Loh, MD

Blood (2019) 134 (Supplement_1): 741.

https://doi.org/10.1182/blood-2019-128977

Published: 2019

Journal Articles

Integrin alpha6-Deletion Induces Apoptosis and Src Signaling Changes in Acute Lymphoblastic Leukemia Cells

Eun Ji Gang, MD PhD, Hye Na Kim, Johanna Scott, PhD, Matthew J Oberley, MDPhD, Etan Orgel, MD MS, Steven D. Mittelman, MDPhD, Yao-Te Hsieh, PhD, Markus Muschen, MD, Deepa Bhojwani, MD, Daniel Braas, PhD, Thomas Graeber, PhD, Nora Heisterkamp, PhD, Yong-Mi Kim, MD MPH, PhD

Blood (2017) 130 (Supplement 1): 3878.

https://doi.org/10.1182/blood.V130.Suppl_1.3878.3878

Published: 2017

Journal Articles

Inhibiting Aurora Kinase B Sensitizes B-Cell Acute Lymphoblastic Leukemia to Glucocorticoids

Coralie Poulard, Hye Na Kim, Celine Gagnieux, Karina Kruth, PhD, Mimi Fang, Daniel Gerke, Deepa Bhojwani, MD, Yong-Mi Kim, MD MPH, PhD, Michael R Stallcup, PhD, Miles A. Pufall, PhD

Blood (2017) 130 (Supplement 1): 5113.

https://doi.org/10.1182/blood.V130.Suppl_1.5113.5113

Published: 2017

Journal Articles

AVA4746, an Orally Available, Clinical Grade Antagonist of Integrin Alpha 4, Sensitizes Pre-B Cell Acute Lymphoblastic Leukemia to Chemotherapy

Yongsheng Ruan, MD, Eun Ji Gang, Hye-Na Kim, Chintan Parekh, MBBS, Hisham Abdel-Azim, MD, Deepa Bhojwani, MD, Alan S. Wayne, MD, Yong-Mi Kim, MD PhD MPH

Blood (2016) 128 (22): 2765.

https://doi.org/10.1182/blood.V128.22.2765.2765

Published: 2016

Journal Articles

a Phase I Trial of Bendamustine in Combination with Clofarabine and Etoposide in Pediatric Patients with Relapsed or Refractory Hematologic Malignancies

Sima Jeha, MD, Monika L. Metzger, MD, Kristine R Crews, PhD, Patrick Campbell, MD PhD, Raul C. Ribeiro, MD, Cheng Cheng, PhD, Melissa Peyton, RN, Carl Panetta, PhD, Jun Yang, PhD, Ching-Hon Pui, MD, Deepa Bhojwani, MD

Blood (2016) 128 (22): 1628.

https://doi.org/10.1182/blood.V128.22.1628.1628

Published: 2016

Journal Articles

Investigating Ethnic Differences in Toxicities of Childhood ALL Therapy

Yasmin Rawlins, BA, Jemily Malvar, MS, Richard Sposto, PhD, Etan Orgel, MD MS, Deepa Bhojwani, MD

Blood (2016) 128 (22): 5989.

https://doi.org/10.1182/blood.V128.22.5989.5989

Published: 2016

Journal Articles

The PI3Kdelta Inhibitor, CAL-101, Inhibits Migration of Primary Pre-B ALL to SDF1alpha: Treatment Implications for Overcoming Cell-Adhesion-Mediated Drug Resistance

EunJi Gang, MDPhD, Hye Na Kim, Yann Duchartre, PhD, Stephanie Nicole Shishido, PhD, Sajad Khazal, MD, Etai Adam, MD, Nour Abdel-Azim, Chintan Parekh, MBBS, Hisham Abdel-Azim, MD, Deepa Bhojwani, MD, Nora Heisterkamp, PhD, Alan S. Wayne, MD, Yong-Mi Kim, MDPhDMPH

Blood (2015) 126 (23): 2526.

https://doi.org/10.1182/blood.V126.23.2526.2526

Published: 2015

Journal Articles

A Novel CD49d Targeting Antisense, ATL1102, Effectively Mobilizes Acute Myeloid Leukemia Cells

Yann Duchartre, PhD, EunJi Gang, MDPhD, Hye Na Kim, Stephanie Nicole Shishido, PhD, Muller Fabbri, MD, Anatoly Grishin, PhD, Chintan Parekh, MBBS, Hisham Abdel-Azim, MD, Deepa Bhojwani, MD, Alan S. Wayne, MD, George Tachas, PhD, Yong-Mi Kim, MDPhDMPH

Blood (2015) 126 (23): 3807.

https://doi.org/10.1182/blood.V126.23.3807.3807

Published: 2015

Journal Articles

Association Between Acute Leukoencephalopathy and Long-Term Neurobehavioral and Brain Imaging Outcomes in Survivors of Childhood Acute Lymphoblastic Leukemia Treated with Chemotherapy Only

Yin Ting Cheung, PhD, Noah D. Sabin, MD JD, Wilburn E. Reddick, PhD, Deepa Bhojwani, MD, Wei Liu, PhD, Tara M. Brinkman, PhD, John O. Glass, PhD, DeoKumar Srivastava, PhD, Leslie L. Robison, PhD MPH, Ching-Hon Pui, MD, Melissa M. Hudson, MD, Kevin R. Krull, PhD

Blood (2015) 126 (23): 3255.

https://doi.org/10.1182/blood.V126.23.3255.3255

Published: 2015

Journal Articles

Risk Factors For Acute Pancreatitis In Patients With Acute Lymphoblastic Leukemia

Chengcheng Liu, Deqing Pei, MS, Meenakshi Devidas, PhD, Cheng Cheng, PhD, Wenjian Yang, PhD, Scott C. Howard, MD, Mignon L. Loh, MD, Paul L. Martin, MD, PhD, Naomi J. Winick, MD, William Paul Bowman, MD, Eric C. Larsen, MD, William L. Carroll, MD, Elizabeth A. Raetz, MD, Deepa Bhojwani, MD, Sima Jeha, MD, Ching-Hon Pui, MD, William E. Evans, PharmD, Stephen P. Hunger, MD, Mary V. Relling, PharmD

Blood (2013) 122 (21): 3868.

https://doi.org/10.1182/blood.V122.21.3868.3868

Published: 2013

Journal Articles

Inherited GATA3 genetic Variants Are Associated With Childhood BCR-ABL1 -Like Acute Lymphoblastic Leukemia and Increased Risk Of Relapse

Virginia Perez-Andreu, MD PhD, Kathryn G. Roberts, PhD, Richard C. Harvey, PhD, Wenjian Yang, PhD, Cheng Cheng, PhD, Deqing Pei, MS, Heng Xu, PhD, Julie Gastier-Fostier, PhD, Shuyu E, PhD, Joshua Yew-Suang Lim, I-Ming L. Chen, Yiping Fan, PhD, Meenakshi Devidas, PhD, Michael J. Borowitz, MD, PhD, Colton Smith, PhD, Geoffrey A. Neale, PhD, Esteban Gonzalez Burchard, MD, MPH, Dara G Torgerson, PhD, Federico Antillon, MD, Cesar Rolando, B.S., Naomi J. Winick, MD, Bruce Camitta, MD, Elizabeth A. Raetz, MD, Brent L. Wood, MD, PhD, Feng Yue, PhD, William L. Carroll, MD, Eric C. Larsen, MD, William Paul Bowman, MD, Mignon L. Loh, MD, Michael Dean, PhD, Deepa Bhojwani, MD, Ching-Hon Pui, MD, William E. Evans, PharmD, Mary V. Relling, PharmD, Stephen P. Hunger, MD, Cheryl L. Willman, MD, Charles G. Mullighan, MBBS, MSc, MD, FRACP, FRCPA, Jun J. Yang, PhD

Blood (2013) 122 (21): 617.

https://doi.org/10.1182/blood.V122.21.617.617

Published: 2013

Journal Articles

A Phase 1/2 Study Of Blinatumomab In Pediatric Patients With Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia

Blood (2013) 122 (21): 70.

https://doi.org/10.1182/blood.V122.21.70.70

Published: 2013

Journal Articles

IKZF1 and 22q11.22 Deletions and PDGFRA Gains Are Associated with Poor Outcome in Down Syndrome Acute Lymphoblastic Leukemia

Blood (2012) 120 (21): 289.

https://doi.org/10.1182/blood.V120.21.289.289

Published: 2012

Journal Articles

PDE4B Modulates Glucocorticoid Sensitivity in Childhood Acute Lymphoblastic Leukemia

Blood (2012) 120 (21): 530.

https://doi.org/10.1182/blood.V120.21.530.530

Published: 2012

NARROW

Pre-CAR Blinatumomab Is Associated with Increased Post-CD19 CAR Relapse and Decreased Event Free Survival

Cortical Thinning and Neuropsychologic Measures Predict CD19 CAR T Cell Therapy-Associated Neurotoxicity

Targeting of Integrin α4/VCAM-1 with AVA4746 Modulates the Redox-Status and Metabolism in ALL and Angiogenesis

Cell Adhesion of ALL to Stromal Cells May Mediate CAR T-Cell Resistance: A Novel Escape Mechanism for Immunotherapy

Immunologic and Brain Bases of Neurotoxicity Associated with CAR T-Cell Therapy

Phase 1 Study of Decitabine and Vorinostat Followed By Fludarabine, Cytarabine and G-CSF (FLAG) in Children, Adolescents and Young Adults with Relapsed/Refractory AML: Report from the Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL) Consortium

A Phase 2 Trial of Inotuzumab Ozogamicin (InO) in Children and Young Adults with Relapsed or Refractory (R/R) CD22+ B-Acute Lymphoblastic Leukemia (B-ALL): Results from Children's Oncology Group Protocol AALL1621

Integrin alpha6-Deletion Induces Apoptosis and Src Signaling Changes in Acute Lymphoblastic Leukemia Cells

Inhibiting Aurora Kinase B Sensitizes B-Cell Acute Lymphoblastic Leukemia to Glucocorticoids

AVA4746, an Orally Available, Clinical Grade Antagonist of Integrin Alpha 4, Sensitizes Pre-B Cell Acute Lymphoblastic Leukemia to Chemotherapy

a Phase I Trial of Bendamustine in Combination with Clofarabine and Etoposide in Pediatric Patients with Relapsed or Refractory Hematologic Malignancies

Investigating Ethnic Differences in Toxicities of Childhood ALL Therapy

The PI3Kdelta Inhibitor, CAL-101, Inhibits Migration of Primary Pre-B ALL to SDF1alpha: Treatment Implications for Overcoming Cell-Adhesion-Mediated Drug Resistance

A Novel CD49d Targeting Antisense, ATL1102, Effectively Mobilizes Acute Myeloid Leukemia Cells

Association Between Acute Leukoencephalopathy and Long-Term Neurobehavioral and Brain Imaging Outcomes in Survivors of Childhood Acute Lymphoblastic Leukemia Treated with Chemotherapy Only

Risk Factors For Acute Pancreatitis In Patients With Acute Lymphoblastic Leukemia

Inherited GATA3 genetic Variants Are Associated With Childhood BCR-ABL1 -Like Acute Lymphoblastic Leukemia and Increased Risk Of Relapse

A Phase 1/2 Study Of Blinatumomab In Pediatric Patients With Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia

IKZF1 and 22q11.22 Deletions and PDGFRA Gains Are Associated with Poor Outcome in Down Syndrome Acute Lymphoblastic Leukemia

PDE4B Modulates Glucocorticoid Sensitivity in Childhood Acute Lymphoblastic Leukemia

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American Society of Hematology

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American Society of Hematology

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