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Dennis A. Carson, M.D.
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Journal Articles

Inhibition Of Wnt Signaling In Chronic Lymphocytic Leukemia Has Synergistic Cytotoxicity With Ibrutinib

Christina C.N. Wu, PhD, Michael Y. Choi, MD, Fitzgerald Lao, Thomas J. Kipps, MD, PhD, Dennis A. Carson, M.D.
Journal: Blood
Blood (2013) 122 (21): 5306.
https://doi.org/10.1182/blood.V122.21.5306.5306
Published: 2013
Journal Articles

Preclinical Development Of ROR1 Peptide Based Vaccine With Activity Against Chronic Lymphocytic Leukemia In ROR1 Transgenic Mice

Jian Yu, PhD, Bing Cui, Ph.D., George F. Widhopf, II, PhD, Liguang Chen, MD, PhD, Laura Rassenti, PhD, Zhengran Wang, BS, Shuyu Ma, BS, Tomoko Hayashi, M.D., Ph.D., Dennis A. Carson, M.D., Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4174.
https://doi.org/10.1182/blood.V122.21.4174.4174
Published: 2013
Journal Articles

Cirmtuzumab Vedotin (UC-961ADC3), An Anti-ROR1-Monomethyl Auristatin E Antibody-Drug Conjugate, Is a Potential Treatment For ROR1-Positive Leukemia and Solid Tumors

Bing Cui, Ph.D, George F. Widhopf, II, PhD, Charles E. Prussak, Ph.D., Christina C.N. Wu, PhD, Anil Sadarangani, PhD, Suping Zhang, PhD, Fitzgerald Lao, Catriona HM Jamieson, MD, PhD, Dennis A. Carson, M.D, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1637.
https://doi.org/10.1182/blood.V122.21.1637.1637
Published: 2013
Journal Articles

Targeting Of Chronic Lymphocytic Leukemia B Cells With a Humanized Monoclonal Antibody Specific For ROR1

George F. Widhopf, II, PhD, Bing Cui, Ph.D., Christina C.N. Wu, PhD, Jian Yu, PhD, Fitzgerald Lao, Rommel Tawatao, Rongrong Wu, Esther Avery, B.S., Anil Sadarangani, PhD, Charles Prussak, PhD, Catriona HM Jamieson, MD, PhD, Dennis A. Carson, M.D., Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2873.
https://doi.org/10.1182/blood.V122.21.2873.2873
Published: 2013
Journal Articles

A Highly Selective Anti-ROR1 Monoclonal Antibody Inhibits Human Acute Myeloid Leukemia CD34+ Cell Survival and Self-Renewal.

Larissa Balaian, Ph.D., Anil Sadarangani, Ph.D., George F. Widhopf, II, PhD, Rui-kun Zhong, MD, Charles Prussak, PhD, Marco A. Marra, PhD, John E Dick, PhD, Mark D. Minden, MD, PhD, Edward D. Ball, M.D., Dennis A. Carson, M.D., Catriona Jamieson, MD, PhD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 2560.
https://doi.org/10.1182/blood.V120.21.2560.2560
Published: 2012
Journal Articles

Selective Clearance of Chronic Lymphocytic Leukemia Cells in Vivo Following Treatment with UC99961, an Anti-ROR1 Monoclonal Antibody

Eva Hellqvist, Ph.D, Christina C.N. Wu, Ph.D., George F. Widhopf, II, PhD, Alice Shih, Rommel Tawatao, Fitzgerald Lao, Bing Cui, Ph.D., Charles Prussak, PhD, Anil Sadarangani, Ph.D., Dennis A. Carson, M.D., Catriona Jamieson, MD, PhD, Thomas J. Kipps, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3886.
https://doi.org/10.1182/blood.V120.21.3886.3886
Published: 2012
Journal Articles

Selective Inhibition of Activated B-Cell Lymphoma Cells by a Novel Small Molecule Inhibitor of NF-κB

John T, Norton, PhD, Tomoko Hayashi, M.D., Ph.D., Raymond P. Wu, Ph.D., Howard Cottam, PhD, Dennis A. Carson, M.D.
Journal: Blood
Blood (2011) 118 (21): 2498.
https://doi.org/10.1182/blood.V118.21.2498.2498
Published: 2011
Journal Articles

Increased Activity of Aldehyde Dehydrogenase, a Stem/Progenitor Cell Marker, in Chronic Lymphocytic Leukemia,

Raymond P. Wu, Ph.D., Christina C.N. Wu, Ph.D., Tomoko Hayashi, M.D., Ph.D., Laura Z. Rassenti, Ph.D., Thomas J. Kipps, M.D., Ph.D, Dennis A. Carson, M.D.
Journal: Blood
Blood (2011) 118 (21): 3867.
https://doi.org/10.1182/blood.V118.21.3867.3867
Published: 2011
Journal Articles

Agelastatin A (AgA), a Marine Sponge Derived Alkaloid, Inhibits Wnt/Beta-Catenin Signaling and Selectively Induces Apoptosis in Chronic Lymphocytic Leukemia Independently of p53

Michael Y. Choi, MD, Johanna Melo Cardenas, BSc, Desheng Lu, MD, PhD, Jian Yu, PhD, E. Paige Stout, PhD, Raymond P. Wu, Ph.D., John M Horton, B.S., Allison Gomez, Julio A. Diaz-Perez, M.D., M.S., Dennis A. Carson, M.D., Tadeusz F. Molinski, PhD, Thomas J. Kipps, M.D., Ph.D, Januario E. Castro, M.D.
Journal: Blood
Blood (2011) 118 (21): 1786.
https://doi.org/10.1182/blood.V118.21.1786.1786
Published: 2011
Journal Articles

Tcl-1 Inhibits Nuclear Export of TR3 and Is Highly Expressed in ZAP70-Positive CLL B-Cells.

Irene M. Pedersen, Ph.D., Frederic Luciano, Ph.D., Xiao-kun Zhang, Ph.D., Carlo M. Croce, Ph.D., Thomas J. Kipps, M.D., Ph.D., Dennis A. Carson, M.D., Ph.D., John C. Reed, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 967.
https://doi.org/10.1182/blood.V104.11.967.967
Published: 2004