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Journal Articles

C-Myc- Dependent Stabilization of Hif-1alpha in MM: Therapeutic Implications

Klaus Podar, MD, MSc, PhD, Jing Zhang, MS, Giovanni Tonon, MD, PHD, Clemens Grabher, MSc, PHD, Samir Lababidi, PHD, Marc S Raab, MD, Sonia Vallet, MD, Yiming Zhou, PHD, Marie-Astrid Cartron, MS, Martin Sattler, PhD, Dharminder Chauhan, JD, PHD, Kenneth C Anderson, MD

Blood (2008) 112 (11): 2750.

https://doi.org/10.1182/blood.V112.11.2750.2750

Published: 2008

Journal Articles

Mcl-1 Fragment Mcl-1(128–350) Induces Inhibition of Multiple Myeloma Cell Proliferation and Apoptosis Via Both Upregulation of C-Jun as Well as Modulation of Its Transcriptional Activity

Klaus Podar, MD, MSc, PhD, Jing Zhang, MS, Alexander Zimmerhackl, DI, Daniela Barila, PHD, Sonia Vallet, MD, Martin Sattler, PhD, Yu-Tzu Tai, PhD, Teru Hideshima, MD, PhD, Dharminder Chauhan, JD, PHD, Kenneth C. Anderson, MD

Blood (2008) 112 (11): 2751.

https://doi.org/10.1182/blood.V112.11.2751.2751

Published: 2008

Journal Articles

Upregulation of c-Jun Induces Cell Death Via Caspase-Triggered c-Abl Cleavage in Human Multiple Myeloma.

Klaus Podar, MD, MSc, PhD, Marc S. Raab, MD, Giovanni Tonon, MD, PhD, Martin Sattler, PhD, Daniela Barila, PhD, Yu-Tzu Tai, PhD, Hiroshi Yasui, MD, PhD, Noopur Raje, MD, Ronald A. Depinho, MD, Teru Hideshima, MD, PhD, Dharminder Chauhan, JD, PhD, Kenneth C. Anderson, MD

Blood (2006) 108 (11): 3415.

https://doi.org/10.1182/blood.V108.11.3415.3415

Published: 2006

Journal Articles

Targeting Src- Family Kinase Activation and Downstream Molecular Events To Overcome MM Cell Growth, Survival, and Drug- Resistance.

Klaus Podar, MD, PhD, Yu-Tzu Tai, PhD, Dean Abtahi, BS, Marc S. Raab, MD, Hiroshi Yasui, MD, PhD, Kenji Ishitsuka, MD, PhD, Norihiko Shiraishi, PhD, Laurence P. Catley, MD, Martin Sattler, PhD, Noopur Raje, MD, Teru Hideshima, MD, PhD, Dharminder Chauhan, JD, PhD

Blood (2005) 106 (11): 1583.

https://doi.org/10.1182/blood.V106.11.1583.1583

Published: 2005

Journal Articles

The PKC- Inhibitor Enzastaurin Inhibits MM Cell Growth, Survival and Migration in the Bone Marrow Microenvironment.

Klaus Podar, MD, PhD, Marc S. Raab, MD, Dean Abtahi, BS, Yu-Tzu Tai, PhD, Boris Lin, MD, PhD, Nikhil C. Munshi, MD, Teru Hideshima, MD, PhD, Dharminder Chauhan, JD, PhD, Kenneth C. Anderson, MD

Blood (2005) 106 (11): 1584.

https://doi.org/10.1182/blood.V106.11.1584.1584

Published: 2005

Journal Articles

Novel Hydroxamic Acid-Derived HDAC Inhibitor LBH589 Potently Activates Intrinsic and Extrinsic Apoptotic Pathways, and Induces Tubulin Hyperacetylation in Multiple Myeloma.

Laurence Catley, MBBS, FRACP, FRCPA, Yu-Tzu Tai, PhD, Teru Hideshima, MD, PhD, Dharminder Chauhan, JD, PhD, Ellen Weisberg, PhD, Tanyel Kiziltepe, PhD, Paola Neri, MD, Pierfrancesco Tassone, MD, Richard Versace, PhD, Peter Atadja, PhD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD

Blood (2005) 106 (11): 1578.

https://doi.org/10.1182/blood.V106.11.1578.1578

Published: 2005

Journal Articles

Alkylphosphocholine Perifosine Inhibits Myeloma Cell Growth While Inducing Myeloid Hyperplasia in a Murine Myeloma Model.

Laurence Catley, MBBS, FRACP, FRCPA, Teru Hideshima, MD, PhD, Dharminder Chauhan, JD, PhD, Paola Neri, MD, Piefrancesco Tassone, MD, Yu-Tzu Tai, PhD, Weihua Song, MD, Daniel R. Carrasco, MD, PhD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD

Blood (2005) 106 (11): 1579.

https://doi.org/10.1182/blood.V106.11.1579.1579

Published: 2005

Journal Articles

Up-Regulation of c-Jun contributes to the Induction of Apoptosis by Adaphostin in Human Multiple Myeloma Cells.

Klaus Podar, MD, PhD, Giovanni Tonon, MD, PhD, Marc S. Raab, MD, Martin Sattler, PhD, Dean Abtahi, BS, Yu-Tzu Tai, PhD, Steven LeGouill, MD, PhD, Kenji Ishitsuka, MD, PhD, Hiroshi Yasui, MD, PhD, Ron A. Depinho, MD, Teru Hideshima, MD, PhD, Dharminder Chauhan, JD, PhD, Kenneth C. Anderson, MD

Blood (2005) 106 (11): 1585.

https://doi.org/10.1182/blood.V106.11.1585.1585

Published: 2005

Journal Articles

The Tyrosine Kinase Inhibitor Adaphostin (NSC 680410), but Not Imatinib Mesylate, Inhibits Survival and Src Tyrosine Kinase Family- Triggered Signaling Pathways of MM Cells.

Klaus Podar, MD, PhD, Melissa Simoncini, BS, Yu-Tzu Tai, PhD, Martin Sattler, PhD, Kenji Ishitsuka, MD, PhD, Steven Le Gouill, MD, Makoto Hamasaki, MD, PhD, Renate Burger, PhD, Noopur Raje, MD, Teru C. Hideshima, MD, PhD, Dharminder Chauhan, JD, PhD, Kenneth Anderson, MD

Blood (2004) 104 (11): 3352.

https://doi.org/10.1182/blood.V104.11.3352.3352

Published: 2004

Journal Articles

Effects of the Indazolylpyrimidine GW786034 on Angiogenesis and MM Cell Growth: Therapeutic Implications.

Klaus Podar, MD, PhD, Melissa Simoncini, BS, Steven Le Gouill, MD, Yu-Tzu Tai, PhD, Shaji Kumar, MD, Pierfrancesco Tassone, MD, Laurence P. Catley, MD, Lini N. Pandite, MD, Rakesh Kumar, PhD, Teru Hideshima, MD, PhD, Dharminder Chauhan, JD, PhD, Kenneth C. Anderson, MD

Blood (2004) 104 (11): 2452.

https://doi.org/10.1182/blood.V104.11.2452.2452

Published: 2004

Journal Articles

Caveolin-1 Is Required for VEGF- Triggered Multiple Myeloma Cell Migration and Is Targeted by Bortezomib (Velcade®).

Klaus Podar, MD, PhD, Reshma Shringarpure, PhD, Yu-Tzu Tai, PhD, Melissa Simoncini, BS, Martin Sattler, PhD, Kenji Ishitsuka, MD, PhD, Paul G. Richardson, MD, Teru Hideshima, MD, PhD, Dharminder Chauhan, JD, PhD, Anderson C. Kenneth, MD

Blood (2004) 104 (11): 2453.

https://doi.org/10.1182/blood.V104.11.2453.2453

Published: 2004

NARROW

C-Myc- Dependent Stabilization of Hif-1alpha in MM: Therapeutic Implications

Mcl-1 Fragment Mcl-1(128–350) Induces Inhibition of Multiple Myeloma Cell Proliferation and Apoptosis Via Both Upregulation of C-Jun as Well as Modulation of Its Transcriptional Activity

Upregulation of c-Jun Induces Cell Death Via Caspase-Triggered c-Abl Cleavage in Human Multiple Myeloma.

Targeting Src- Family Kinase Activation and Downstream Molecular Events To Overcome MM Cell Growth, Survival, and Drug- Resistance.

The PKC- Inhibitor Enzastaurin Inhibits MM Cell Growth, Survival and Migration in the Bone Marrow Microenvironment.

Novel Hydroxamic Acid-Derived HDAC Inhibitor LBH589 Potently Activates Intrinsic and Extrinsic Apoptotic Pathways, and Induces Tubulin Hyperacetylation in Multiple Myeloma.

Alkylphosphocholine Perifosine Inhibits Myeloma Cell Growth While Inducing Myeloid Hyperplasia in a Murine Myeloma Model.

Up-Regulation of c-Jun contributes to the Induction of Apoptosis by Adaphostin in Human Multiple Myeloma Cells.

The Tyrosine Kinase Inhibitor Adaphostin (NSC 680410), but Not Imatinib Mesylate, Inhibits Survival and Src Tyrosine Kinase Family- Triggered Signaling Pathways of MM Cells.

Effects of the Indazolylpyrimidine GW786034 on Angiogenesis and MM Cell Growth: Therapeutic Implications.

Caveolin-1 Is Required for VEGF- Triggered Multiple Myeloma Cell Migration and Is Targeted by Bortezomib (Velcade®).

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American Society of Hematology

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ASH Publications

American Society of Hematology

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