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Journal Articles

Treatment‐Related Acute Myeloid Leukemia in Children

Katharina Waack, Katharina Röllecke, PhD, Mareike Rasche, MD, Christiane Walter, MSc, Ursula Creutzig, MD PhD, Dirk Reinhardt, MD PhD

Blood (2019) 134 (Supplement_1): 1322.

https://doi.org/10.1182/blood-2019-131911

Published: 2019

Journal Articles

Characteristics and Outcomes of Pediatric Patients with t(16;16)-AML: Results of a Case Series By the International BFM Study Group

Kim Klein, MD MSc, Valerie de Haas, MD PhD, Jonas Abrahamsson, MD PhD, Todd A Alonzo, PhD, Brenda Gibson, MD PhD, Christine J Harrison, PhD FRCPath, Henrik Hasle, MD PhD, Betsy A Hirsch, PhD, Guy Leverger, MD PhD, Franco Locatelli, MD PhD, Susana C. Raimondi, PhD, Jeffrey E Rubnitz, MD PhD, Dirk Reinhardt, MD PhD, Daisuke Tomizawa, MD PhD, Gertjan J.L. Kaspers, MD PhD

Blood (2017) 130 (Supplement 1): 2671.

https://doi.org/10.1182/blood.V130.Suppl_1.2671.2671

Published: 2017

Journal Articles

Amplicon Based Panel Targeted Resequencing Identified ZRSR2 As a Potential New Favorable Marker in Pediatric AML

Christiane Walter, MSc, Zhenyu Xu, PhD, Martin Zimmermann, PhD, Dirk Reinhardt, MD PhD, Nils Von Neuhoff, PhD

Blood (2016) 128 (22): 2905.

https://doi.org/10.1182/blood.V128.22.2905.2905

Published: 2016

Journal Articles

Successes and Challenges of Pediatric AML: A Report on Survival, Salvage Therapy and Causes of Deaths in the AML-BFM Study Group from 1987 -2012

Mareike Rasche, MD, Martin Zimmermann, PhD, Lisa Kellerstrass, Ursula Creutzig, MD PhD, Jan-Henning Klusmann, MD, Dirk Reinhardt, MD PhD

Blood (2016) 128 (22): 450.

https://doi.org/10.1182/blood.V128.22.450.450

Published: 2016

Journal Articles

Genomic Landscape of Pediatric Mixed Phenotype Acute Leukemia

Thomas B. Alexander, MD MPH, Zhaohui Gu, PhD, John K Choi, MD, Mignon L. Loh, MD, John Horan, MD MPH, Barbara Buldini, MD, Giuseppe Basso, Sarah Elitzur, MD, C. Michel Zwaan, MD PhD, Valerie de Haas, MD PhD, Allen Eng Juh Yeoh, MD, Dirk Reinhardt, MD PhD, Daisuke Tomizawa, MD, PhD, Tim Lammens, Barbara De Moerloose, MD, Li Zhou, PhD, Hiroki Hori, MD PhD, Anthony V. Moorman, PhD, Andrew S. Moore, MBBS FRACP PhD, Ondrej Hrusak, MD PhD, Soheil Meshinchi, MD PhD, Etan Orgel, MD MS, Meenakshi Devidas, PhD, Stephen P. Hunger, MD, Jamie M Guidry Auvil, Malcolm A. Smith, MD PhD, Tanja M. Davidsen, PhD, Leandro C. Hermida, Patee Gesuwan, Marco A. Marra, PhD, Yussanne Ma, PhD, Andrew J. Mungall, Richard Moore, PhD, Daniela S. Gerhard, PhD, Xueyuan Cao, Lei Shi, PhD, Stanley Pounds, PhD, Hiroto Inaba, MD PhD, Charles Mullighan, MBBS, MSc, MD

Blood (2016) 128 (22): 454.

https://doi.org/10.1182/blood.V128.22.454.454

Published: 2016

Journal Articles

The Prognostic Impact of Cytogenetics and Karyotype Changes in Pediatric Patients with Relapsed Acute Myeloid Leukemia: A Retrospective Cohort Study within the Relapsed AML 2001/01 Study

Blood (2016) 128 (22): 2896.

https://doi.org/10.1182/blood.V128.22.2896.2896

Published: 2016

Journal Articles

Evaluation of Genetic Mutations in Plasma Exosomes As a Biomarker Tool for Detecting the Clonal Evolution of Leukemic Cells in Pediatric AML

Fabienne Kunz, Katarina Reinhardt, PhD, Nils Von Neuhoff, PhD, Karl Welte, MD, Dirk Reinhardt, MD PhD, Basant Kumar Thakur, PhD

Blood (2016) 128 (22): 1711.

https://doi.org/10.1182/blood.V128.22.1711.1711

Published: 2016

Journal Articles

Gemtuzumab in Children with Relapsed and Refractory Acute Myeloid Leukemia Treated on Compassionate-Use Basis: A Report of the AML-BFM Study Group

Mareike Rasche, MD, Beate Lerius, Ursula Creutzig, MD PhD, Martin Zimmermann, PhD, C. Michel Zwaan, MD PhD, Dirk Reinhardt, MD PhD

Blood (2016) 128 (22): 1637.

https://doi.org/10.1182/blood.V128.22.1637.1637

Published: 2016

Journal Articles

The miRNA-193 Family Is a Potent Tumor-Suppressor and a Biomarker for Poor Prognosis in Acute Myeloid Leukemia

Blood (2016) 128 (22): 1534.

https://doi.org/10.1182/blood.V128.22.1534.1534

Published: 2016

Journal Articles

Acute Leukemia of Ambiguous Lineage: A Comprehensive Survival Analysis Enables Designing New Treatment Strategies

Ondrej Hrusak, MD PhD, Valerie De Haas, MD PhD, Ales Luks, Iveta Janotova, Ester Mejstrikova, MD PhD, Kirsten Bleckmann, MD, Anja Moricke, MD, Julie Irving, PhD, Benigna Konatkowska, Thomas B. Alexander, MD MPH, Hiroto Inaba, MD PhD, Kjeld Schmiegelow, MD DMSc, Simone Stokley, FRCPath,, Jorge Gabriel Rossi, PhD, Maria Sara Felice, MD PhD, Luciano Dalla-Pozza, MB BS FRACP, Jessa Morales, Michael Dworzak, MD, Barbara Buldini, MD, Giuseppe Basso, Myriam Campbell, Maria Elena Cabrera, Neda Marinov, Sarah Elitzur, MD, Shai Izraeli, MD, Drorit Luria, PhD, Tamar Feuerstein, PhD, Alexandra Kolenova, MD PhD, Peter Svec, Elena Kreminska, Karen R. Rabin, MD, Sophia Polychronopoulou, MD PhD, Elaine da Costa, Hanne Vibeke Marquart, MD PhD, Antonis Kattamis, MD, Richard Ratei, Dirk Reinhardt, MD PhD, Anthony V Moorman, PhD, Martin Schrappe, MD, Jan Stary, MD D.Sc.

Blood (2016) 128 (22): 584.

https://doi.org/10.1182/blood.V128.22.584.584

Published: 2016

Journal Articles

Clofarabine in Combination with High-Dose Cytarabine and Liposomal Daunorubicin in Pediatric AML: Results of a Phase 1B Combination Study By the ITCC Consortium

Christian M. Zwaan, MD PhD, Michael Dworzak, MD PhD, Thomas Klingebiel, MD, Claudia Rössig, MD, Guy Leverger, MD, Jan Stary, Evelina S. de Bont, MDPhD, Satianand Ramnarain, MSc, Yves Bertrand, MD, Benoit Brethon, MD, Brigitte Strahm, MD, Gertjan J. Kaspers, MD PhD, Dirk Reinhardt, MD PhD

Blood (2014) 124 (21): 989.

https://doi.org/10.1182/blood.V124.21.989.989

Published: 2014

Journal Articles

Results of a Feasibility and Phase II Study on Bortezomib (BTZ) in Pediatric Multiply Relapsed or Refractory Acute Lymphoblastic Leukemia: Complete Hematological Responses with a Modestly Intensive Regimen Including BTZ

Gertjan Kaspers, MD PhD, Denise Niewerth, MSc, Satianand Ramnarain, MSc, Andishe Attarbaschi, MD, André Baruchel, MD, Evelina S De Bont, MDPhD, Franca Fagioli, MD, Barbara De Moerloose, MD PhD, Karsten Nysom, MD, Giuseppe Palumbo, MD, Dirk Reinhardt, MD PhD, Pierre-Simon Rohrlich, MDPhD, Pauline Simon, MD, Arend von Stackelberg, MD, C. Michel Zwaan, MD PhD

Blood (2014) 124 (21): 2290.

https://doi.org/10.1182/blood.V124.21.2290.2290

Published: 2014

Journal Articles

GATA1-Centered Genetic Network on Chromosome 21 Drives Down Syndrome Acute Megakaryoblastic Leukemia

Lena Stachorski, Dirk Heckl, PhD, Veera Raghavan Thangapandi, Aliaksandra Maroz, PhD, Dirk Reinhardt, MD PhD, Jan-Henning Klusmann, MD

Blood (2014) 124 (21): 4310.

https://doi.org/10.1182/blood.V124.21.4310.4310

Published: 2014

Journal Articles

Clinical Impact of Additional Cytogenetic Aberrations, cKIT- and RAS Mutations and Other Factors in Pediatric t(8;21)-AML

Blood (2014) 124 (21): 481.

https://doi.org/10.1182/blood.V124.21.481.481

Published: 2014

Journal Articles

Analysis of WT1 Mutations and Combined Aberrations in Childhood Acute Myeloid Leukemia using Whole Exome Sequencing

Nils von Neuhoff, PhD, Peter Husemann, PhD, Robert Geffers, PhD, Christiane Walter, M.Sc., Christine von Neuhoff, MD, Martin Zimmermann, PhD, Brigitte Schlegelberger, MD, Dirk Reinhardt, MD PhD

Blood (2014) 124 (21): 2340.

https://doi.org/10.1182/blood.V124.21.2340.2340

Published: 2014

Journal Articles

IKZF1 deletions in Pediatric Acute Myeloid Leukemia

Jasmijn de Rooij, MD, Eva Beuling, PhD, C. Michel Zwaan, Askar Obulkasim, André Baruchel, MD, Jan Trka, MD PhD, Dirk Reinhardt, MD PhD, Edwin Sonneveld, PhD, Brenda Gibson, Martin Zimmermann, Rob Pieters, MD PhD, Marry van den Heuvel-Eibrink, MD PhD, Maarten Fornerod, PhD

Blood (2014) 124 (21): 2346.

https://doi.org/10.1182/blood.V124.21.2346.2346

Published: 2014

Journal Articles

Mimicking the Bone Marrow Niche in Vitro : Establishment of a 3D Perfusion Culture System for Mesenchymal Stromal Cells

Lika Drakhlis, B.Sc., Christiane Walter, M.Sc., Maike Hinrichs, PhD, Katarina Reinhardt, PhD, Dirk Reinhardt, MD PhD, Nils von Neuhoff, PhD

Blood (2014) 124 (21): 5136.

https://doi.org/10.1182/blood.V124.21.5136.5136

Published: 2014

Journal Articles

ETV6 Aberrations Are a Recurrent Event in Pediatric Acute Myeloid Leukemia with Poor Clinical Outcome

Jasmijn de Rooij, MD, Eva Beuling, PhD, Maarten Fornerod, PhD, Askar Obulkasim, André Baruchel, MD, Jan Trka, MD, PhD, Prof., Dirk Reinhardt, MD PhD, Edwin Sonneveld, PhD, Martin Zimmermann, Rob Pieters, MD PhD, Marry van den Heuvel-Eibrink, MD PhD, C. Michel Zwaan, MD PhD

Blood (2014) 124 (21): 1012.

https://doi.org/10.1182/blood.V124.21.1012.1012

Published: 2014

Journal Articles

Microrna-106b~25 Cluster Is Involved in Relapsed MLL -Rearranged Pediatric AML

Lonneke Verboon, Maarten Fornerod, PhD, Askar Obulkasim, Edwin Sonneveld, PhD, André Baruchel, MD, Jan Trka, MD PhD, Dirk Reinhardt, MD PhD, Rob Pieters, MD PhD, Jacqueline Cloos, PhD, Gertjan JL Kaspers, MD PhD, Jan-Henning Klusmann, MD, C. Michel Zwaan, MD PhD, Marry van den Heuvel-Eibrink, MD PhD

Blood (2014) 124 (21): 1038.

https://doi.org/10.1182/blood.V124.21.1038.1038

Published: 2014

Journal Articles

Single Cell Whole Exome Sequencing in NPM1/Flt3 Positive Pediatric Acute Myeloid Leukemia

Christiane Walter, M.Sc., Winfried Hofmann, Dr. rer. nat., Katarina Reinhardt, PhD, Dirk Reinhardt, MD PhD, Nils von Neuhoff, PhD

Blood (2014) 124 (21): 1043.

https://doi.org/10.1182/blood.V124.21.1043.1043

Published: 2014

NARROW

Treatment‐Related Acute Myeloid Leukemia in Children

Characteristics and Outcomes of Pediatric Patients with t(16;16)-AML: Results of a Case Series By the International BFM Study Group

Amplicon Based Panel Targeted Resequencing Identified ZRSR2 As a Potential New Favorable Marker in Pediatric AML

Successes and Challenges of Pediatric AML: A Report on Survival, Salvage Therapy and Causes of Deaths in the AML-BFM Study Group from 1987 -2012

Genomic Landscape of Pediatric Mixed Phenotype Acute Leukemia

The Prognostic Impact of Cytogenetics and Karyotype Changes in Pediatric Patients with Relapsed Acute Myeloid Leukemia: A Retrospective Cohort Study within the Relapsed AML 2001/01 Study

Evaluation of Genetic Mutations in Plasma Exosomes As a Biomarker Tool for Detecting the Clonal Evolution of Leukemic Cells in Pediatric AML

Gemtuzumab in Children with Relapsed and Refractory Acute Myeloid Leukemia Treated on Compassionate-Use Basis: A Report of the AML-BFM Study Group

The miRNA-193 Family Is a Potent Tumor-Suppressor and a Biomarker for Poor Prognosis in Acute Myeloid Leukemia

Acute Leukemia of Ambiguous Lineage: A Comprehensive Survival Analysis Enables Designing New Treatment Strategies

Clofarabine in Combination with High-Dose Cytarabine and Liposomal Daunorubicin in Pediatric AML: Results of a Phase 1B Combination Study By the ITCC Consortium

Results of a Feasibility and Phase II Study on Bortezomib (BTZ) in Pediatric Multiply Relapsed or Refractory Acute Lymphoblastic Leukemia: Complete Hematological Responses with a Modestly Intensive Regimen Including BTZ

GATA1-Centered Genetic Network on Chromosome 21 Drives Down Syndrome Acute Megakaryoblastic Leukemia

Clinical Impact of Additional Cytogenetic Aberrations, cKIT- and RAS Mutations and Other Factors in Pediatric t(8;21)-AML

Analysis of WT1 Mutations and Combined Aberrations in Childhood Acute Myeloid Leukemia using Whole Exome Sequencing

IKZF1 deletions in Pediatric Acute Myeloid Leukemia

Mimicking the Bone Marrow Niche in Vitro : Establishment of a 3D Perfusion Culture System for Mesenchymal Stromal Cells

ETV6 Aberrations Are a Recurrent Event in Pediatric Acute Myeloid Leukemia with Poor Clinical Outcome

Microrna-106b~25 Cluster Is Involved in Relapsed MLL -Rearranged Pediatric AML

Single Cell Whole Exome Sequencing in NPM1/Flt3 Positive Pediatric Acute Myeloid Leukemia

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American Society of Hematology

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American Society of Hematology

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