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Ebenezer David, PhD
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Journal Articles

SF1126, a Novel PI3K Inhibitor Results in Downstream Inhibition of the PI3K Axis and Displays Sequence Specific Synergy When Combined with Bortezomib in Multiple Myeloma Cells

Ebenezer David, PhD, Xiaodong Peng, PhD, Benjamin G Barwick, Jonathan L Kaufman, MD, Joseph R Garlich, PhD, Sagar Lonial, MD
Journal: Blood
Blood (2008) 112 (11): 5167.
https://doi.org/10.1182/blood.V112.11.5167.5167
Published: 2008
Journal Articles

Imipramine Blue, a Tricyclic Compound and An Inhibitor of NADPH Oxidase Induces G2/M Cell Cycle Arrest Followed by Apoptosis in Multiple Myeloma Cells and in Leukemia Cells

Ebenezer David, PhD, Jonathan L Kaufman, MD, Jack Arbiser, MD, Sagar Lonial, MD
Journal: Blood
Blood (2008) 112 (11): 5170.
https://doi.org/10.1182/blood.V112.11.5170.5170
Published: 2008
Journal Articles

Patulin Acts Synergistically with Doxorubicin and Bortezomib in Cytotoxicity against Hematological Malignancies

Alex Hessel, Malefa Tselanyane, PhD, Fengrong Wang, MD, PhD, Ebenezer David, PhD, Sagar Lonial, MD, Edmund K. Waller, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 2664.
https://doi.org/10.1182/blood.V112.11.2664.2664
Published: 2008
Journal Articles

Combination of Bortezomib with Tipifarnib (R115777) Induces Synergistic Myeloma Cell Apoptosis Via Down-Regulation of HDAC6 and Inhibition of Aggresome Formation.

Ebenezer David, PhD, Katherine Schafer-Hales, Adam I. Marcus, PhD, Jonathan L. Kaufman, MD, Sagar Lonial, MD
Journal: Blood
Blood (2007) 110 (11): 1520.
https://doi.org/10.1182/blood.V110.11.1520.1520
Published: 2007
Journal Articles

A Novel Pan-PI3K/Akt Inhibitor, SF1126, Inhibits In Vitro Growth of Multiple Myeloma Cells.

Jeannine Silberman, MD, Kimberly Dalbey, BS, Claire Torre, Ebenezer David, PhD, Leif Bergsagel, MD, Donald Durden, MD, PhD, Joseph Garlich, PhD, Ulrich Schwertschlag, MD, PhD, Sagar Lonial, MD
Journal: Blood
Blood (2007) 110 (11): 4806.
https://doi.org/10.1182/blood.V110.11.4806.4806
Published: 2007
Journal Articles

Perifosine Induces DR4/DR5 Expression Leading to Apoptosis That Can Be Enhanced with Exogenous TRAIL, and Blocked with Strategies Directed at DR4/DR5 Inhibition.

Ebenezer David, PhD, Rajni Sinha, MD, Jonathan L. Kaufman, MD, Sagar Lonial, MD
Journal: Blood
Blood (2006) 108 (11): 3446.
https://doi.org/10.1182/blood.V108.11.3446.3446
Published: 2006
Journal Articles

Combination of Akt/PKB Inhibition (Perifosine) and Farnesyl Transferase Inhibition (Tipifarnib) Results in Increased Cell Death in Myeloma Cells Lines.

Rajni Sinha, MD, Ebenezer David, PhD, Emily Zeilter, Claire Torre, Jonathan L. Kaufman, MD, Sagar Lonial, MD
Journal: Blood
Blood (2005) 106 (11): 1568.
https://doi.org/10.1182/blood.V106.11.1568.1568
Published: 2005
Journal Articles

Combination of Farnesyl Transferase Inhibitor (Tipifarnib) with Perifosine Induces Apoptosis through phos-PDK1 in Human Lymphoma and Leukemia Cell Lines.

Ebenezer David, PhD, Rajni Sinha, MD, Claire Torre, Jonathan L. Kaufman, MD, Sagar Lonial, MD
Journal: Blood
Blood (2005) 106 (11): 1488.
https://doi.org/10.1182/blood.V106.11.1488.1488
Published: 2005
Journal Articles

Combination of Farnesyl Transferase Inhibition (Lonafarnib) and Proteasome Inhibition (Bortezomib) Results in Rapid Caspase Activation and down Regulation of p-AKT in Myeloma cell Lines and Primary Myeloma Cells.

Ebenezer David, PhD, Shi-Yong Sun, PhD, Fadlo R. Khuri, MD, Sagar Lonial, MD
Journal: Blood
Blood (2004) 104 (11): 2471.
https://doi.org/10.1182/blood.V104.11.2471.2471
Published: 2004