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Edwin Chen, PhD
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Journal Articles

Zinc-Dependent Homomultimerization of Mutant Calreticulin Is Required for MPN Pathogenesis

Jeanne F Rivera, BSc, April Joy Baral, MSc, Rachael Smyth, MSc, Fatima Nadat, PhD, Emma Burman, BSc, Ghadah Alameer, MSc, Sally A Boxall, PhD, Brian R Jackson, PhD, Ann Mullally, MD, Edwin Chen, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 312.
https://doi.org/10.1182/blood-2019-124005
Published: 2019
Journal Articles

STAG2 Mutations Alter Cohesin Ring Function and Provide Therapeutic Vulnerabilities in Acute Myeloid Leukemia

Zuzana Tothova, MD PhD, John M. Krill-Burger, MS, Daniel S. Day, PhD, J. Erika Haydu, MD PhD, Brian J. Abraham, PhD, Catherine C. Landers, BA, Edyta Malolepsza, PhD, Christina R. Hartigan, BS, Amie Holmes, PhD, Melanie Donahue, BS, Katerina D. Popova, BA, Sebastian Koochaki, MS, Jeanne Rivera, BSc, Michael Seiler, PhD, Denes Hnisz, PhD, Edwin Chen, PhD, Silvia Buonamici, PhD, Monica Schenone, PhD, Alan D. D'Andrea, MD, Steven A. Carr, PhD, Richard A. Young, PhD, Benjamin L. Ebert, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 940.
https://doi.org/10.1182/blood-2018-99-117480
Published: 2018
Journal Articles

Functional and Molecular Basis of Thrombopoietin Receptor Activation By Mutant Calreticulin

Shannon Elf, PhD, Nouran Abdelfattah, MPhil, April Joy Baral, MSc, BSc, Danielle Beeson, Amy Ko, Natalie Florescu, Edwin Chen, PhD, Ann Mullally, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 382.
https://doi.org/10.1182/blood.V130.Suppl_1.382.382
Published: 2017
Journal Articles

Physical Interaction Between Mutant Calreticulin and the Thrombopoietin Receptor Is Required for Hematopoietic Transformation

Shannon Elf, PhD, Nouran Abdelfattah, MPhil, Edwin Chen, PhD, Javier Perales-Patón, Emily Rosen, BS, Amy Ko, Fabian Peisker, Natalie Florescu, Silvia Giannini, PhD, Ofir Wolach, MD, Elizabeth A. Morgan, MD, Julie-Aurore Losman, MD, PhD, Rebekka K. Schneider, MD, Fatima Al-Shahrour, PhD, Ann Mullally, MD
Journal: Blood
Blood (2015) 126 (23): LBA-4.
https://doi.org/10.1182/blood.V126.23.LBA-4.LBA-4
Published: 2015
Journal Articles

The Recql5 Helicase Is a Novel Downstream Target of Jak2V617F and Maintains Genome Stability in Response to Replication Stress

Edwin Chen, PhD, Jong-Sook Ahn, PhD, Lawrence J Breyfogle, Anthony R Green, PhDFRCP FRCPath, Benjamin L. Ebert, MDPhD, Ann Mullally, MD
Journal: Blood
Blood (2014) 124 (21): 822.
https://doi.org/10.1182/blood.V124.21.822.822
Published: 2014