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Journal Articles

Synthetic Lethality CRISPR Screens in Isogenic iPSCs with Splicing Factor Gene Mutations

Henrik Sperber, PhD, Shailee Vora, BS, MS, Andriana G. Kotini, PhD, Malgorzata Olszewska, MS, Aleksandra Wroblewska, PhD, Brian Brown, PhD, Eirini P. Papapetrou, MD PhD

Blood (2018) 132 (Supplement 1): 3083.

https://doi.org/10.1182/blood-2018-99-111857

Published: 2018

Journal Articles

Induced Pluripotent Stem Cells to Model Blood Diseases

Eirini P. Papapetrou, MD PhD

Blood (2018) 132 (Supplement 1): SCI-15.

https://doi.org/10.1182/blood-2018-99-109425

Published: 2018

Journal Articles

Modeling Calreticulin-Mutant Myeloproliferative Neoplasms with Isogenic Induced Pluripotent Stem Cells

Wei Wang, PhD, Tiansu Wang, PhD, Andriana G. Kotini, PhD, Camelia Iancu-Rubin, PhD, Ronald Hoffman, MD, Eirini P. Papapetrou, MD PhD

Blood (2018) 132 (Supplement 1): 4319.

https://doi.org/10.1182/blood-2018-99-111512

Published: 2018

Journal Articles

Functional Analysis of MYC Deregulation By Diverse Genetic Mechanisms during Hematopoiesis

Nicole Stokes, BA, David Dominguez-Sola, MD PhD, Eirini P. Papapetrou, MD PhD

Blood (2018) 132 (Supplement 1): 1323.

https://doi.org/10.1182/blood-2018-99-110829

Published: 2018

Journal Articles

A Novel iPSC Model Reveals a Role for RUNX1 in the Maintenance of AML Leukemia Stem Cells

Josephine Wesely, PhD MSc, BSc, Andriana G. Kotini, PhD, Maria Georgomanoli, PhD, Hanzhi Luo, PhD, Han Yuan, Franco Izzo, PhD, Dan A. Landau, MD PhD, Christina Leslie, PhD, Michael G. Kharas, PhD, Eirini P. Papapetrou, MD PhD

Blood (2018) 132 (Supplement 1): 772.

https://doi.org/10.1182/blood-2018-99-111506

Published: 2018

Journal Articles

A " De Novo Leukemogenesis" iPSC Model Charts the Clonal Evolution of Acute Myeloid Leukemia

Tiansu Wang, PhD, Andriana G. Kotini, PhD, Eirini P. Papapetrou, MD PhD

Blood (2018) 132 (Supplement 1): 773.

https://doi.org/10.1182/blood-2018-99-111613

Published: 2018

Journal Articles

The Activated TGFβ Pathway in Shwachman Diamond Syndrome Impairs Hematopoiesis and Is Down-Regulated By Deletion of 7q

Melisa Ruiz-Gutierrez, MD PhD, Cailin Joyce, PhD, Ozge Vargel Bolukbasi, PhD, Andriana Kotini, PhD, Gabriela Alexe, Jennifer Whangbo, MD PhD, David Russell, MDPhD, Kimberly Stegmaier, MD, Carl D. Novina, MD PhD, Eirini P. Papapetrou, MD PhD, Akiko Shimamura, MD

Blood (2017) 130 (Supplement 1): 875.

https://doi.org/10.1182/blood.V130.Suppl_1.875.875

Published: 2017

Journal Articles

Modeling Bone Marrow Failure and MDS in Shwachman Diamond Syndrome Using Induced Pluripotent Stem Cells

Melisa Ruiz-Gutierrez, MD PhD, Ozge Vargel Bolukbasi, PhD, Linda Vo, Ryohichi Sugimura, MD PhD, Marilyn Sanchez Bonilla, MS, Andriana Kotini, PhD, Carl D. Novina, MD PhD, George Q. Daley, MD PhD, Eirini P. Papapetrou, MD PhD, Akiko Shimamura, MD PhD

Blood (2016) 128 (22): 1496.

https://doi.org/10.1182/blood.V128.22.1496.1496

Published: 2016

Journal Articles

Isogenic iPSC Models of SRSF2 -Mutant Myelodysplastic Syndrome Capture Disease Phenotypes, Splicing Defects and Drug Responses

Chan-Jung Chang, PhD, Andriana Kotini, PhD, Julie Teruya-Feldstein, MD, Omar Abdel-Wahab, MD, Robert Bradley, PhD, Eirini P. Papapetrou, MD PhD

Blood (2016) 128 (22): 962.

https://doi.org/10.1182/blood.V128.22.962.962

Published: 2016

Journal Articles

Functional Dissection of Chromosome 7q Loss and Haploinsufficient Gene Discovery Using iPSC Models of MDS

Andriana Kotini, PhD, Jeffrey J Delrow, PhD, Timothy A. Graubert, MD, Stephen Nimer, MD, Eirini P Papapetrou, MD PhD

Blood (2014) 124 (21): 524.

https://doi.org/10.1182/blood.V124.21.524.524

Published: 2014

Journal Articles

An iPSC-Based Model Of MDS For Phenotype-Driven Gene and Drug Discovery

Ibrahim Boussaad, PhD, Andriana Kotini, PhD, Emily K Dolezal, Stephen Nimer, MD, Eirini P Papapetrou, MD, PhD

Blood (2013) 122 (21): 859.

https://doi.org/10.1182/blood.V122.21.859.859

Published: 2013

Journal Articles

Chromosome 7q Hemizygosity Recapitulates MDS-Related Cellular Phenotypes In Genetically Engineered Human Pluripotent Stem Cells

Andriana Kotini, PhD, Ibrahim Boussaad, PhD, Eirini P Papapetrou, MD, PhD

Blood (2013) 122 (21): 862.

https://doi.org/10.1182/blood.V122.21.862.862

Published: 2013

Journal Articles

L3MBTL1: A Polycomb Protein At the Node of Crosstalk Between the BMP4 and Hippo Signaling Pathways in Erythropoiesis.

Fabiana Perna, MD, Ly P. Vu, Maria Themeli, MD, PhD, Ruben Hoya-Arias, PhD, Fan Liu, MD, PhD, Lan Wang, PhD, Nadia Gurvich, PhD, Todd Hricik, BS, Eirini P. Papapetrou, MD, PhD, Malcolm A.S. AS Moore, Ross L. Levine, Michel Sadelain, MD, PhD, Stephen Nimer, MD

Blood (2012) 120 (21): 2296.

https://doi.org/10.1182/blood.V120.21.2296.2296

Published: 2012

Journal Articles

IPS Cells From Del(7q)-MDS Patients Display Impaired Proliferation and Hematopoietic Commitment

Ibrahim Boussaad, PhD, Emily K Dolezal, Fabiana Perna, MD, Stephen D Nimer, MD, Eirini P Papapetrou, MD, PhD

Blood (2012) 120 (21): 174.

https://doi.org/10.1182/blood.V120.21.174.174

Published: 2012

Journal Articles

Genomic Safe Harbors in Human iPS Cells

Eirini P. Papapetrou, MD, PhD, Michel Sadelain, MD, PhD, Frederic Bushman, PhD

Blood (2011) 118 (21): SCI-47.

https://doi.org/10.1182/blood.V118.21.SCI-47.SCI-47

Published: 2011

Journal Articles

Targeting a Novel Epigenetic Silencing Mechanism to Efficiently Upregulate Fetal Globin Gene Expression

Fabiana Perna, MD, Ly P. Vu, Maria Themeli, MD, Ruben Hoya-Arias, PhD, Xinyang Zhao, PhD, Eirini P. Papapetrou, MD, PhD, Michel Sadelain, MD, PhD, Stephen D. Nimer, MD

Blood (2011) 118 (21): 352.

https://doi.org/10.1182/blood.V118.21.352.352

Published: 2011

Journal Articles

Therapeutic Transgene Expression From Genomic Safe Harbors In Patient-Specific Induced Pluripotent Stem Cells

Eirini P Papapetrou, MD, PhD, Gabsang Lee, PhD, Nirav Malani, Manu Setty, Isabelle Riviere, PhD, Laxmi MS Tirunagari, Kyuichi Kadota, MD, Shoshannah L Roth, PhD, Patricia Giardina, MD, Agnes Viale, PhD, Christina Leslie, PhD, Frederic Bushman, PhD, Lorenz Studer, MD, Michel Sadelain, MD, PhD

Blood (2010) 116 (21): 564.

https://doi.org/10.1182/blood.V116.21.564.564

Published: 2010

Journal Articles

microRNA-Mediated Gene Regulation Effectively Restricts In Vivo Transgene Expression in Hematopoietic Stem Cell Progeny.

Eirini P. Papapetrou, MD, PhD, Damian Kovalovsky, PhD, Laurent Beloeil, PhD, Derek Sant’Angelo, PhD, Michel Sadelain, MD, PhD

Blood (2007) 110 (11): 193.

https://doi.org/10.1182/blood.V110.11.193.193

Published: 2007

NARROW

Synthetic Lethality CRISPR Screens in Isogenic iPSCs with Splicing Factor Gene Mutations

Induced Pluripotent Stem Cells to Model Blood Diseases

Modeling Calreticulin-Mutant Myeloproliferative Neoplasms with Isogenic Induced Pluripotent Stem Cells

Functional Analysis of MYC Deregulation By Diverse Genetic Mechanisms during Hematopoiesis

A Novel iPSC Model Reveals a Role for RUNX1 in the Maintenance of AML Leukemia Stem Cells

A " De Novo Leukemogenesis" iPSC Model Charts the Clonal Evolution of Acute Myeloid Leukemia

The Activated TGFβ Pathway in Shwachman Diamond Syndrome Impairs Hematopoiesis and Is Down-Regulated By Deletion of 7q

Modeling Bone Marrow Failure and MDS in Shwachman Diamond Syndrome Using Induced Pluripotent Stem Cells

Isogenic iPSC Models of SRSF2 -Mutant Myelodysplastic Syndrome Capture Disease Phenotypes, Splicing Defects and Drug Responses

Functional Dissection of Chromosome 7q Loss and Haploinsufficient Gene Discovery Using iPSC Models of MDS

An iPSC-Based Model Of MDS For Phenotype-Driven Gene and Drug Discovery

Chromosome 7q Hemizygosity Recapitulates MDS-Related Cellular Phenotypes In Genetically Engineered Human Pluripotent Stem Cells

L3MBTL1: A Polycomb Protein At the Node of Crosstalk Between the BMP4 and Hippo Signaling Pathways in Erythropoiesis.

IPS Cells From Del(7q)-MDS Patients Display Impaired Proliferation and Hematopoietic Commitment

Genomic Safe Harbors in Human iPS Cells

Targeting a Novel Epigenetic Silencing Mechanism to Efficiently Upregulate Fetal Globin Gene Expression

Therapeutic Transgene Expression From Genomic Safe Harbors In Patient-Specific Induced Pluripotent Stem Cells

microRNA-Mediated Gene Regulation Effectively Restricts In Vivo Transgene Expression in Hematopoietic Stem Cell Progeny.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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