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Emanuela Leone, PhD
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Journal Articles

Pharmacokinetics and Biodistribution of Locked Nucleic Acid (LNA)-Mir-221 Inhibitor: A New Promising Anti-Myeloma Agent

Maria Eugenia Gallo Cantafio, PhD, Annamaria Gulla, MD, Nicola Amodio, PhD, Emanuela Leone, PhD, Eugenio Morelli, MD, Lavinia Biamonte, PhD, Antonino Neri, Pr, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD, Maria Teresa Di Martino
Journal: Blood
Blood (2015) 126 (23): 3025.
https://doi.org/10.1182/blood.V126.23.3025.3025
Published: 2015
Journal Articles

Growth Inhibition and Synergistic Induction of Apoptosis By Synthetic Mir-125b-5p Mimics and Myc-Targeting Agents in Human Myeloma Cell Lines

Lavinia Biamonte, PhD, Cinzia Federico, PhD, Eugenio Morelli, MD, Emanuela Leone, PhD, Maria Eugenia Gallo Cantafio, PhD, Maria Teresa Di Martino, Nicola Amodio, PhD, Marco Rossi, MD, Antonino Neri, Pr, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD
Journal: Blood
Blood (2015) 126 (23): 3019.
https://doi.org/10.1182/blood.V126.23.3019.3019
Published: 2015
Journal Articles

MiR-29b Counteracts Aberrant HDAC4 Expression and Enhances Vorinostat Activity in Multiple Myeloma

Nicola Amodio, PhD, Marzia Leotta, MD, Anna Maria Gullà, MD, Lavinia Raimondi, PhD, Eugenio Morelli, MD, Maria Angelica Stamato, Teresa Calimeri, MD PhD, Maria Teresa Di Martino, PhD, Marco Rossi, MD, Emanuela Leone, PhD, Antonino Neri, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD
Journal: Blood
Blood (2014) 124 (21): 2060.
https://doi.org/10.1182/blood.V124.21.2060.2060
Published: 2014
Journal Articles

In Vitro and Vivo Activity Against Multiple Myeloma Cells Of a Novel Locked Nucleic Acid (LNA)-Mir-221 Inhibitor

Maria Teresa Di Martino, PhD, Annamaria Gullà, MD, Maria Eugenia Gallo Cantafio, Emanuela Altomare, PhD, Nicola Amodio, PhD, Emanuela Leone, PhD, Santo Giovanni Lio, Eugenio Morelli, MD, Daniele Caracciolo, MD, Cirino Botta, MD, Antonino Neri, MD, Niels M Frandsen, PhD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD
Journal: Blood
Blood (2013) 122 (21): 3166.
https://doi.org/10.1182/blood.V122.21.3166.3166
Published: 2013
Journal Articles

Tumor Suppressor MiR-29b Targets HDAC4 and Modulates Vorinostat Activity In Multiple Myeloma Cells

Nicola Amodio, PhD, Marzia Leotta, MD, Lavinia Biamonte, PhD, Teresa Calimeri, MD, Eugenio Morelli, MD, Umberto Foresta, PhD, Maria Teresa Di Martino, PhD, Marco Rossi, MD, Emanuela Leone, PhD, Antonino Neri, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD
Journal: Blood
Blood (2013) 122 (21): 4451.
https://doi.org/10.1182/blood.V122.21.4451.4451
Published: 2013
Journal Articles

Mir-29b Negatively Regulates Osteoclastic Cell Differentiation and Function: Implications for the Treatment of Multiple Myeloma-Related Bone Disease

Marco Rossi, MD, Maria Rita Pitari, PhD student, Nicola Amodio, PhD, Maria Teresa Di Martino, PhD, Emanuela Leone, PhD, Francesco Conforti, MD, Francesco Maria Paolino, PhD student, Cirino Botta, MD, Teresa Del Giudice, MD, Eleonora Iuliano, MD, Manlio Ferrarini, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD
Journal: Blood
Blood (2012) 120 (21): 3960.
https://doi.org/10.1182/blood.V120.21.3960.3960
Published: 2012
Journal Articles

MiR-29b Exerts Anti-Multiple Myeloma Activity by Targeting Key Oncogenic Pathways and Modulating DNA Methylation Profile.

Nicola Amodio, PhD, Maria Teresa Di Martino, PhD, Umberto Foresta, PhD, Marco Rossi, MD, Marzia Leotta, MD, Emanuela Leone, PhD, Marta Lionetti, PhD, Annamaria Gullà, MD, Patrizia D'Aquila, PhD, Dina Bellizzi, PhD, Giuseppe Passarino, PhD, Fernanda Fabiani, Mariateresa Fulciniti, PhD, Manlio Ferrarini, MD, Fortunato Morabito, Antonino Neri, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD
Journal: Blood
Blood (2012) 120 (21): 2941.
https://doi.org/10.1182/blood.V120.21.2941.2941
Published: 2012
Journal Articles

MiR-34a Replacement As a Novel Therapeutic Approach for Multiple Myeloma: Preclinical In Vitro and In Vivo Evidence

Maria Teresa Di Martino, PhD, Emanuela Leone, PhD, Nicola Amodio, PhD, Umberto Foresta, PhD, Marta Lionetti, PhD, Maria Rita Pitari, PhD, Maria Eugenia Gallo Cantafio, PhD, Annamaria Gullà, Eugenio Morelli, MD, Marzia Leotta, Vera Tomaino, PhD, Marco Rossi, MD, Massimo Negrini, PhD, Manlio Ferrarini, MD, Antonino Neri, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD, Pierosandro Tagliaferri, MD, Pierfrancesco Tassone, MD
Journal: Blood
Blood (2011) 118 (21): 2910.
https://doi.org/10.1182/blood.V118.21.2910.2910
Published: 2011