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Journal Articles

IKZF1 (IKAROS) Deletions Are Independent On BCR-ABL1 Rearrangement and Are Associated with a Peculiar Gene Expression Signature and Poor Prognosis in Adult B-Progenitor Acute Lymphoblastic Leukemia (ALL) Patients.

Blood (2009) 114 (22): 912.

https://doi.org/10.1182/blood.V114.22.912.912

Published: 2009

Journal Articles

Chronic Eosinophilic Leukaemia (CEL) with FIP1L1-PDGFRalpha Rearrangement (F/P): The Response to Imatinib (IM) Is Durable. A Report of 33 Patients with A Follow –up of 30 to 92 Months.

Michela Rondoni, Emanuela Ottaviani, Daniela Cilloni, MD, PhD, Pier Paolo Piccaluga, Stefania Paolini, Ilaria Iacobucci, PhD, Simona Soverini, PhD, Serena Merante, Francesca Messa, PhD, Francesco Buccisano, M.D., Mario Tiribelli, Fabrizio Pane, Giuseppe Saglio, Francesco Lauria, MD, Michele Baccarani, MD, Giovanni Martinelli, MD

Blood (2009) 114 (22): 3894.

https://doi.org/10.1182/blood.V114.22.3894.3894

Published: 2009

Journal Articles

Disabled Gene Is Involved in CML Progression and Its Expression Level at Diagnosis Can Predict Major Molecular Response (MMR) to Imatinib Therapy.

Daniela Cilloni, MD, PhD, Francesca Arruga, PhD, Francesca Messa, PhD, Monica Pradotto, PhD, Enrico Bracco, PhD, Sonia Carturan, PhD, Chiara Maffè, PhD, Emanuela Messa, MD, Antonia Rotolo, MD, Elisabetta Greco, MD, Ilaria Iacobucci, PhD, Roberto Bernardoni, Fabrizio Pane, MD, Thea Kalebic, MD, Giovanni Martinelli, Michele Baccarani, MD, Giuseppe Saglio, MD

Blood (2009) 114 (22): 3964.

https://doi.org/10.1182/blood.V114.22.3964.3964

Published: 2009

Journal Articles

Foxo Transcription Factor Activity Is Retained in Quiescent Chronic Myeloid Leukaemia Stem Cells and Activated by Tyrosine Kinase Inhibitors to Mediate “induced-quiescence” in More Mature progenitors.

Daniela Cilloni, MD, PhD, Francesca Pellicano, PhD, Vignir G Helgason, PhD, Cristina Panuzzo, PhD, Francesca Messa, PhD, Brian J Huntly, MD, Elaine Allan, PhD, Francesca Arruga, PhD, Enrico Bracco, PhD, Giuseppe Saglio, MD, Tessa L Holyoake, MD

Blood (2009) 114 (22): 187.

https://doi.org/10.1182/blood.V114.22.187.187

Published: 2009

Journal Articles

The Oncogenic Kinase Bcr-Abl Directly Regulates Splicing of BclX through a Quaternary Complex Coordinated by Nck-Beta and Sam-68 Adapter Proteins.

Bracco Enrico, Valentina Rosso, Mussino Stefano, Francesca Arruga, Sonia Carturan, PhD, Francesca Messa, PhD, Cristina Panuzzo, PhD, Marco Lo Iacono, Paolo Nicoli, MD, Emanuela Messa, MD, Antonia Rotolo, Monica Pradotto, PhD, Alessandro Morotti, MD, Alessandra Balbo, Ilaria Iacobucci, PhD, Giovanni Martinelli, MD, Daniela Cilloni, MD, PhD, Giuseppe Saglio, MD

Blood (2009) 114 (22): 2171.

https://doi.org/10.1182/blood.V114.22.2171.2171

Published: 2009

Journal Articles

Genome-Wide Screening for Dominant Modifiers in Drosophila Identified New Cluster of Genes Involved in BCR-ABL Signalling and CML Progression.

Francesca Messa, PhD, Monica Pradotto, PhD, Francesca Arruga, PhD, Roberto Bernardoni, PhD, Enrico Bracco, PhD, Chiara Maffè, PhD, Emanuela Messa, MD, Sonia Carturan, PhD, Elisabetta Signorino, PhD, Elisabetta Greco, MD, Antonia Rotolo, MD, Ilaria Iacobucci, PhD, Giovanni Martinelli, MD, Giuseppe Saglio, MD, Daniela Cilloni, MD, PhD

Blood (2009) 114 (22): 2186.

https://doi.org/10.1182/blood.V114.22.2186.2186

Published: 2009

Journal Articles

Identification of Rab5 as a Gene Involved in Chronic Myeloid Leukemia (CML) Progression.

Daniela Cilloni, MD, PhD, Monica Pradotto, PhD, Francesca Messa, PhD, Francesca Arruga, PhD, Enrico Bracco, PhD, Sonia Carturan, PhD, Chiara Maffè, PhD, Emanuela Messa, MD, Antonia Rotolo, MD, Elisabetta Greco, MD, Ilaria Iacobucci, PhD, Thea Kalebic, MD, Roberto Bernardoni, Fabrizio Pane, MD, Giovanni Martinelli, MD, Michele Baccarani, M.D., Giuseppe Saglio, MD

Blood (2009) 114 (22): 3470.

https://doi.org/10.1182/blood.V114.22.3470.3470

Published: 2009

Journal Articles

Whole Transcriptome Sequencing of a Philadelphia-Positive Acute Lymphoblastic Leukemia (ALL) with “Next Generation Sequencing” Technology Revealed Novel Point Mutations Associated with Disease-Progression.

Blood (2009) 114 (22): 3074.

https://doi.org/10.1182/blood.V114.22.3074.3074

Published: 2009

Journal Articles

Single Base Pair Mutation Detection by PNA Direct PCR Clamping: Application to Bcr-Abl T315I Mutation

Blood (2008) 112 (11): 4224.

https://doi.org/10.1182/blood.V112.11.4224.4224

Published: 2008

Journal Articles

The Re-Activation of FoxO3 Transcription Factor in Acute Myeloid Leukaemia Is Responsible for the Induction of a Quiescent Status of Leukaemic Progenitor Cells.

Daniela Cilloni, Cristina Panuzzo, PhD, Francesca Arruga, PhD, Francesca Messa, PhD, Monica Pradotto, PhD, Enrico Bracco, PhD, Alessandro Morotti, MD, Emanuela Messa, Antonia Rotolo, Ilaria Iacobucci, Chiara Marrè, Marisa Pautasso, Giovanni Martinelli, MD, Giuseppe Saglio

Blood (2008) 112 (11): 929.

https://doi.org/10.1182/blood.V112.11.929.929

Published: 2008

Journal Articles

Imatinib Induced Re-Activation of FoxO3 Transcription Factor in CML Is Responsible for the Induction of a Quiescent Status of CD34 Leukaemic Progenitor Cells.

Daniela Cilloni, MD, PhD, Cristina Panuzzo, PhD, Francesca Messa, PhD, Francesca Arruga, PhD, Enrico Bracco, PhD, Roberto Bernardoni, PhD, Sonia Carturan, PhD, Marisa Pautasso, MD, Emanuela Messa, MD, Alessandro Morotti, MD, Monica Pradotto, PhD, Ilaria Iacobucci, Thea Kalebic, MD, Giovanni Martinelli, MD, Giuseppe Saglio, MD

Blood (2008) 112 (11): 1090.

https://doi.org/10.1182/blood.V112.11.1090.1090

Published: 2008

Journal Articles

Identification of Genes Sustaining Bcr-Abl Oncogenic Signalling and CML Progression through a Genetic Tool Based on Human Bcr-Abl Transgenic Drosophila Melanogaster.

Daniela Cilloni, Francesca Messa, PhD, Roberto Bernardoni, PhD, Francesca Arruga, PhD, Monica Pradotto, PhD, Enrico Bracco, PhD, Cristina Panuzzo, PhD, Chiara Maffè, PhD, Emanuela Messa, MD, Ilaria Iacobucci, Thea Kalebic, MD, Giovanni Martinelli, MD, Michele Baccarani, MD, Giuseppe Saglio, MD

Blood (2008) 112 (11): 1091.

https://doi.org/10.1182/blood.V112.11.1091.1091

Published: 2008

Journal Articles

EphA3 Kinase Is Constitutively Activated in Chronic Myeloid Leukaemia during Progression to Accelerated and Blast Crisis and It Could Represent a New Molecular Target.

Daniela Cilloni, MD, PhD, Francesca Arruga, PhD, Sonia Carturan, PhD, Francesca Messa, PhD, Monica Pradotto, PhD, Ilaria Defilippi, PhD, Marisa Pautasso, MD, Ilaria Iacobucci, PhD, Giovanni Martinelli, MD, Enrico Bracco, PhD, Thea Kalebic, MD, Martin Lackmann, PhD, Giuseppe Saglio, MD

Blood (2008) 112 (11): 1092.

https://doi.org/10.1182/blood.V112.11.1092.1092

Published: 2008

Journal Articles

Nck Beta Adapter Protein Coordinates Bcr-Abl/Sam68 Intermolecular Interaction.

Enrico Bracco, PhD, Erika Deklic, Valentina Rosso, Stefano Mussino, PhD, Francesca Arruga, PhD, Sonia Carturan, PhD, Francesca Messa, PhD, Ilaria Defilippi, PhD, Cristina Panuzzo, PhD, Paolo Nicoli, Emanuela Messa, MD, Antonia Rotolo, Roberto Pedrola, Alessandro Morotti, MD, Alessandra Balbo, Ilaria Iacobucci, PhD, Giovanni Martinelli, Daniela Cilloni, Giuseppe Saglio

Blood (2008) 112 (11): 1093.

https://doi.org/10.1182/blood.V112.11.1093.1093

Published: 2008

Journal Articles

Deferasirox Is the Only Iron Chelator Acting as a Potent NF-KB Inhibitor in Myelodysplastic Syndromes

Emanuela Messa, MD, Ilaria Defilippi, PhD, Antonella Roetto, PhD, Francesca Messa, PhD, Francesca Arruga, PhD, Sonia Carturan, PhD, Valentina Rosso, PhD, Enrico Bracco, PhD, Daniela Cilloni, Giuseppe Saglio, MD

Blood (2008) 112 (11): 2671.

https://doi.org/10.1182/blood.V112.11.2671.2671

Published: 2008

Journal Articles

The Non Receptor Transmembrane Tyrosine Kinase STYK1 Represents a Novel Lymphocyte Marker, Whose Expression Is Deregulated in Leukemia, and a Potential Molecular Druggable Target

Blood (2008) 112 (11): 5334.

https://doi.org/10.1182/blood.V112.11.5334.5334

Published: 2008

Journal Articles

Extreme Variability of FIP1L1-PDGFRalpha Transcripts Do Not Influence to Imatinib Mesylate Response in CEL: Clinical Follow-up and Molecular Analysis of the Italian Multicenter Prospective Study

Michela Rondoni, Daniela Cilloni, Stefania Paolini, Emanuela Ottaviani, Francesca Messa, PhD, Pier Paolo Piccaluga, Ilaria Iacobucci, PhD, Francesco Buccisano, M.D., Mario Tiribelli, Monica Bocchia, Francesco Lauria, Serena Merante, Fabrizio Pane, Giuseppe Saglio, MD, Michele Baccarani, MD, Giovanni Martinelli

Blood (2008) 112 (11): 5223.

https://doi.org/10.1182/blood.V112.11.5223.5223

Published: 2008

Journal Articles

Variable but Consistent Pattern of Meningioma 1 Gene (MN1) Expression in Different Genetic Subsets of Acute Myelogenous Leukaemia and Its Potential Use as Marker for Minimal Residual Disease Detection.

Daniela Cilloni, MD, PhD, Francesca Arruga, PhD, Francesca Messa, PhD, Sonia Carturan, PhD, Enrico Bracco, PhD, Emanuela Messa, MD, Cinzia Bittoto, PhD, Cinzia Boveri, PhD, Paolo Nicoli, MD, Ilaria Defilippi, PhD, Renata Catalano, PhD, Giovanni Martinelli, MD, Francesco Lo Coco, MD, Giuseppe Saglio, MD

Blood (2007) 110 (11): 3494.

https://doi.org/10.1182/blood.V110.11.3494.3494

Published: 2007

Journal Articles

FoxO Transcription Factor Is Delocalized in CML Patients by Bcr-Abl Induced PI3K/AKT Activation and IKK Pathway and Can Be Reactivated by Imatinib Treatment.

Daniela Cilloni, MD, PhD, Cristina Panuzzo, PhD, Francesca Messa, PhD, Francesca Arruga, PhD, Paolo Nicoli, MD, Emanuela Messa, MD, Stefano Ulisciani, MD, Ilaria Iacobucci, PhD, Giovanni Martinelli, MD, Enrico Bracco, PhD, Thea Kalebic, MD, Giuseppe Saglio, MD

Blood (2007) 110 (11): 1010.

https://doi.org/10.1182/blood.V110.11.1010.1010

Published: 2007

Journal Articles

FoxO Transcription Factor Is Delocalized and Inactivated in Acute Myeloid Leukaemia Patients.

Daniela Cilloni, MD, PhD, Cristina Panuzzo, PhD, Francesca Messa, PhD, Francesca Arruga, PhD, Paolo Nicoli, MD, Emanuela Messa, MD, Sonia Carturan, PhD, Ilaria Defilippi, PhD, Ilaria Iacobucci, PhD, Valentina Rosso, PhD, Giovanni Martinelli, MD, Enrico Bracco, PhD, Giuseppe Saglio, MD

Blood (2007) 110 (11): 1251.

https://doi.org/10.1182/blood.V110.11.1251.1251

Published: 2007

NARROW

IKZF1 (IKAROS) Deletions Are Independent On BCR-ABL1 Rearrangement and Are Associated with a Peculiar Gene Expression Signature and Poor Prognosis in Adult B-Progenitor Acute Lymphoblastic Leukemia (ALL) Patients.

Chronic Eosinophilic Leukaemia (CEL) with FIP1L1-PDGFRalpha Rearrangement (F/P): The Response to Imatinib (IM) Is Durable. A Report of 33 Patients with A Follow –up of 30 to 92 Months.

Disabled Gene Is Involved in CML Progression and Its Expression Level at Diagnosis Can Predict Major Molecular Response (MMR) to Imatinib Therapy.

Foxo Transcription Factor Activity Is Retained in Quiescent Chronic Myeloid Leukaemia Stem Cells and Activated by Tyrosine Kinase Inhibitors to Mediate “induced-quiescence” in More Mature progenitors.

The Oncogenic Kinase Bcr-Abl Directly Regulates Splicing of BclX through a Quaternary Complex Coordinated by Nck-Beta and Sam-68 Adapter Proteins.

Genome-Wide Screening for Dominant Modifiers in Drosophila Identified New Cluster of Genes Involved in BCR-ABL Signalling and CML Progression.

Identification of Rab5 as a Gene Involved in Chronic Myeloid Leukemia (CML) Progression.

Whole Transcriptome Sequencing of a Philadelphia-Positive Acute Lymphoblastic Leukemia (ALL) with “Next Generation Sequencing” Technology Revealed Novel Point Mutations Associated with Disease-Progression.

Single Base Pair Mutation Detection by PNA Direct PCR Clamping: Application to Bcr-Abl T315I Mutation

The Re-Activation of FoxO3 Transcription Factor in Acute Myeloid Leukaemia Is Responsible for the Induction of a Quiescent Status of Leukaemic Progenitor Cells.

Imatinib Induced Re-Activation of FoxO3 Transcription Factor in CML Is Responsible for the Induction of a Quiescent Status of CD34 Leukaemic Progenitor Cells.

Identification of Genes Sustaining Bcr-Abl Oncogenic Signalling and CML Progression through a Genetic Tool Based on Human Bcr-Abl Transgenic Drosophila Melanogaster.

EphA3 Kinase Is Constitutively Activated in Chronic Myeloid Leukaemia during Progression to Accelerated and Blast Crisis and It Could Represent a New Molecular Target.

Nck Beta Adapter Protein Coordinates Bcr-Abl/Sam68 Intermolecular Interaction.

Deferasirox Is the Only Iron Chelator Acting as a Potent NF-KB Inhibitor in Myelodysplastic Syndromes

The Non Receptor Transmembrane Tyrosine Kinase STYK1 Represents a Novel Lymphocyte Marker, Whose Expression Is Deregulated in Leukemia, and a Potential Molecular Druggable Target

Extreme Variability of FIP1L1-PDGFRalpha Transcripts Do Not Influence to Imatinib Mesylate Response in CEL: Clinical Follow-up and Molecular Analysis of the Italian Multicenter Prospective Study

Variable but Consistent Pattern of Meningioma 1 Gene (MN1) Expression in Different Genetic Subsets of Acute Myelogenous Leukaemia and Its Potential Use as Marker for Minimal Residual Disease Detection.

FoxO Transcription Factor Is Delocalized in CML Patients by Bcr-Abl Induced PI3K/AKT Activation and IKK Pathway and Can Be Reactivated by Imatinib Treatment.

FoxO Transcription Factor Is Delocalized and Inactivated in Acute Myeloid Leukaemia Patients.

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American Society of Hematology

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American Society of Hematology

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