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Fyodor D. Urnov, PhD
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Journal Articles

Regulatory Reprogramming of Erythropoiesis By DNMT3A Mutation

Janghee Woo, MDPhD, Sandra Stehling-Sun, PhD, H. Joachim Deeg, MD, Thalia Papayannopoulou, MD DrSci, Fyodor D Urnov, PhD, John A Stamatoyannopoulos, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4343.
https://doi.org/10.1182/blood-2018-99-120110
Published: 2018
Journal Articles

Potent and Timed Epigenetic Repression of PD-1 in Human T Cells

Jocelynn Pearl, PhD, Fyodor D Urnov, PhD, John A Stamatoyannopoulos, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3493.
https://doi.org/10.1182/blood-2018-99-119011
Published: 2018
Journal Articles

Genome Editing of the Bcl11A Erythroid Specific Enhancer in Bone Marrow Derived Hematopoietic Stem and Progenitor Cells for the Treatment of Sickle Cell Disease

Siyuan Tan, PhD, Kai-Hsin Chang, PhD, Sarah Smith, BS, Kai Chen, MS, Timonthy Sullivan, BS, Qianhe Zhou, PhD, Andreas Reik, PhD, Fyodor D Urnov, PhD, Edward J. Rebar, PhD, Olivier Danos, PhD, Haiyan Jiang, PhD
Journal: Blood
Blood (2015) 126 (23): 203.
https://doi.org/10.1182/blood.V126.23.203.203
Published: 2015
Journal Articles

Clonal Analysis of Human Bone Marrow CD34+ Cells Edited By BCL11A-Targeting Zinc Finger Nucleases Reveals Clinically Relevant Levels of Fetal Globin Expression in Edited Erythroid Progeny

Kai-Hsin Chang, PhD, Timothy Sullivan, MS, Mei Liu, BS, Xiao Yang, PhD, Chao Sun, PhD, Benjamin Vieira, BS, Ming Zhang, PhD, Vu P. Hong, PhD, Kai Chen, MS, Sarah Smith, BS, Siyuan Tan, PhD, Andreas Reik, PhD, Fyodor D Urnov, PhD, Edward J. Rebar, PhD, Olivier Danos, PhD, Haiyan Jiang, PhD
Journal: Blood
Blood (2015) 126 (23): 3234.
https://doi.org/10.1182/blood.V126.23.3234.3234
Published: 2015
Journal Articles

Clinical-Scale Genome Editing of the Human BCL11A Erythroid Enhancer for Treatment of the Hemoglobinopathies

Fyodor D Urnov, PhD, Andreas Reik, PhD, Jeff Vierstra, PhD, Kai-Hsin Chang, PhD, Yuanyue Zhou, Andrea Mich, Jennifer Adrian, Lisa Fox, Nikoletta Psatha, PhD, Siyuan Tan, PhD, Evangelia Yannaki, MD, Stewart Craig, PhD, Edward J. Rebar, PhD, John Stamatoyannopoulos, MD, Thalia Papayannopoulou, MD, George Stamatoyannopoulos, MD DSci, Haiyan Jiang, PhD
Journal: Blood
Blood (2015) 126 (23): 204.
https://doi.org/10.1182/blood.V126.23.204.204
Published: 2015
Journal Articles

Taking it to the Clinic: Genome Editing for Blood Disorders

Fyodor D. Urnov, PhD
Journal: Blood
Blood (2014) 124 (21): SCI-12.
https://doi.org/10.1182/blood.V124.21.SCI-12.SCI-12
Published: 2014
Journal Articles

Autologous Hematopoietic Stem/Progenitor Cell (HSPC) Therapy For Monogenic Blood Disorders: Scalable, cGMP-Compliant Process For Generating Highly Efficient Genome Edited HSPC

Gary K Lee, PhD, Lynn Truong, Travis Wood, Jill Henley, Lee Ya-Li, Ken Kim, Yuanyue Zhou, Jianbin Wang, Ph.D., Andreas Reik, PhD, Fyodor D Urnov, PhD, Paula Cannon, Ph.D., Michael C. Holmes, PhD, Dale Ando, M.D., Martin A Giedlin, Ph.D.
Journal: Blood
Blood (2013) 122 (21): 4213.
https://doi.org/10.1182/blood.V122.21.4213.4213
Published: 2013
Journal Articles

Targeted Gene Modification In Hematopoietic Stem Cells: A Potential Treatment For Thalassemia and Sickle Cell Anemia

Andreas Reik, PhD, Kai-Hsin Chang, PhD, Sandra Stehling-Sun, PhD, Yuanyue Zhou, Gary K Lee, PhD, Lynn Truong, Travis Wood, Ziying Zhang, Albert Luong, Andy Chan, Pei-Qi Liu, PhD, Jeffrey C Miller, PhD, David E Paschon, PhD, Dmitry Y Guschin, PhD, Lei Zhang, PhD, Evangelia Yannaki, MD, Martin A Giedlin, PhD, Edward J Rebar, PhD, Philip D Gregory, PhD, Fyodor D Urnov, PHD, Thalia Papayannopoulou, MD, George Stamatoyannopoulos, MD, DSci
Journal: Blood
Blood (2013) 122 (21): 434.
https://doi.org/10.1182/blood.V122.21.434.434
Published: 2013