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Journal Articles

In Vivo HSC Transduction and Selection Results in Long-Term, High-Level Expression of Human Gamma Globin in Peripheral Blood Erythrocytes of Mice

Andre Lieber, MD PhD, Hongjie Wang, PhD, Nikoleta Psatha, PhD, Chang Li, PhD, Kevin G Haworth, BS, PhD, Anja Ehrhardt, PhD, Zsuzsanna Izsvak, Hans-Peter Kiem, MD PhD, George Stamatoyannopoulos, MD, Thalia Papayannopoulou, MD

Blood (2017) 130 (Supplement 1): 4616.

https://doi.org/10.1182/blood.V130.Suppl_1.4616.4616

Published: 2017

Journal Articles

Introduction of Two Simultaneous Mutations By Genome Editing Greatly Enhances the Accumulation of the Endogenous Fetal Hemoglobin in Human Normal Erythroid Cells

Nikoleta Psatha, PhD, Chang Li, PhD, Hongjie Wang, PhD, Demetri Dalas, George Stamatoyannopoulos, MD, Thalia Papayannopoulou, MD, Andre Lieber, MD PhD

Blood (2017) 130 (Supplement 1): 947.

https://doi.org/10.1182/blood.V130.Suppl_1.947.947

Published: 2017

Journal Articles

Clinical-Scale Genome Editing of the Human BCL11A Erythroid Enhancer for Treatment of the Hemoglobinopathies

Fyodor D Urnov, PhD, Andreas Reik, PhD, Jeff Vierstra, PhD, Kai-Hsin Chang, PhD, Yuanyue Zhou, Andrea Mich, Jennifer Adrian, Lisa Fox, Nikoletta Psatha, PhD, Siyuan Tan, PhD, Evangelia Yannaki, MD, Stewart Craig, PhD, Edward J. Rebar, PhD, John Stamatoyannopoulos, MD, Thalia Papayannopoulou, MD, George Stamatoyannopoulos, MD DSci, Haiyan Jiang, PhD

Blood (2015) 126 (23): 204.

https://doi.org/10.1182/blood.V126.23.204.204

Published: 2015

Journal Articles

PDCD2 Knockdown Promoted Induced Erythroid Differentiation in TF-1 Cells

Yanming Li, Shuge Liu, Hongzhu QU, Yadong Yang, Nan Ding, Xiuyan Ruan, George Stamatoyannopoulos, MD DSci, Xiangdong Fang

Blood (2014) 124 (21): 1331.

https://doi.org/10.1182/blood.V124.21.1331.1331

Published: 2014

Journal Articles

Plerixafor+G-CSF-Mobilized Blood From Thalassemic Mice Provides High Yields Of Long-Term Repopulating Cells With Enhanced Engrafting Capacity : Implications For Human Stem Cell Gene Therapy

Nikoleta Psatha, PhD student, Eleni Sgouramali, BSc, Athanasios Siametis, BSc, Elena Siapati, PhD, Panayotis Baliakas, MD, Varnavas Constantinou, MD, Achilles Anagnostopoulos, MD, Thalia Papayannopoulou, MD, George Stamatoyannopoulos, MD, Evangelia Yannaki, MD

Blood (2013) 122 (21): 4211.

https://doi.org/10.1182/blood.V122.21.4211.4211

Published: 2013

Journal Articles

Targeted Gene Modification In Hematopoietic Stem Cells: A Potential Treatment For Thalassemia and Sickle Cell Anemia

Blood (2013) 122 (21): 434.

https://doi.org/10.1182/blood.V122.21.434.434

Published: 2013

Journal Articles

Talen-Mediated Knock Outs Of Cis and Trans Elements Potentially Involved In Globin Gene Switching

Patrick A Navas, PHD, Yongqi Yan, PhD, Minerva E Sanchez, BS, Ericka M Johnson, BS, George Stamatoyannopoulos, MD, DSci

Blood (2013) 122 (21): 436.

https://doi.org/10.1182/blood.V122.21.436.436

Published: 2013

Journal Articles

Hematopoietic Cell Mobilization for Gene Therapy of Adult Patients with Severe Beta-Thalassemia: The Challenge of Splenectomy and the Role of Plerixafor

Evangelia Yannaki, MD, Thalia Papayannopoulou, Erica Jonlin, PhD, Fani Zervou, Garyfalia Karponi, Angeliki Xagorari, PhD, Pamela S. Becker, MD, PhD, Nikoleta Psatha, Ioannis Batsis, MD, Panayotis Kaloyannidis, MD, Varvara Tahynopoulou, Varnavas Constantinou, Asimenia Bouinta, Konstantia Kotta, Aglaia Athanassiadou, PhD, Achilles Anagnostopoulos, Athanasios Fassas, MD, George Stamatoyannopoulos, MD, DSci

Blood (2011) 118 (21): 166.

https://doi.org/10.1182/blood.V118.21.166.166

Published: 2011

Journal Articles

Limitations of G-CSF Mobilization in Splenectomized Patients with Beta-Thalassemia Major: Implications for Thalassemia Gene Therapy.

Evangelia Yannaki, MD, Thalia Papayannopoulou, MD, Erica Jonlin, PhD, Ioannis Batsis, MD, Pamela S. Becker, MD, PhD, Fani Zervou, BS, Angeliki Xagorari, PhD, Garyfalia Karponi, BS, Varvara Tahynopoulou, BS, Panayotis Kaloyannidis, MD, Varnavas Constantinou, MD, Achilles Anagnostopoulos, MD, Athanasios Fassas, MD, George Stamatoyannopoulos, MD, DSci

Blood (2009) 114 (22): 2150.

https://doi.org/10.1182/blood.V114.22.2150.2150

Published: 2009

Journal Articles

Potent Induction of Human γ Globin Gene Expression by Largazole, a New Histone Deacetylase Inhibitor.

Hua Cao, MD, PhD, Rui Gao Fei, MD, Albert A. Bowers, Thomas J. Greshock, Tenaya Newkirt, Kenneth A. Miller, James E. Bradner, MD, Nathan West, Robert M. Williams, Thalia Papayannopoulou, MD, George Stamatoyannopoulos, MD, DSci

Blood (2009) 114 (22): 2022.

https://doi.org/10.1182/blood.V114.22.2022.2022

Published: 2009

Journal Articles

Chromatin Profiling of the Globin Loci of Human ES Cells and ES-Derived Erythroid Cells.

Xiangdong Fang, PhD, MD, Kai-Hsin Chang, Daniel Bates, Morgan Diegel, Richard Sandstrom, Molly Weaver, Michael O. Dorschner, Peter J. Sabo, Thalia Papayannopoulou, MD, George Stamatoyannopoulos, MD, DSci, John Stamatoyannopoulos

Blood (2009) 114 (22): 2535.

https://doi.org/10.1182/blood.V114.22.2535.2535

Published: 2009

Journal Articles

A Contigs Strategy of Southern Blot Hybridization: Screening for DNase I Hypersensitive Sites in the 200 Kb Region 5′ to the B-Globin Locus LCR.

Ping Xiang, PhD, Hemei Han, BS, Xiangdong Fang, PhD, George Stamatoyannopoulos, MD, PhD, Qiliang Li, PhD

Blood (2004) 104 (11): 1219.

https://doi.org/10.1182/blood.V104.11.1219.1219

Published: 2004

Journal Articles

Erythroid-Specific Intergenic Transcripts Originate from the 200 Kb Region 5′ to the LCR in Erythroleukemia and Human Primary Cells.

Ping Xiang, PhD, Xiangdong Fang, MD, PhD, Wenxuan Yin, PhD, George Stamatoyannopoulos, MD, PhD, Qiliang Li, PhD

Blood (2004) 104 (11): 1218.

https://doi.org/10.1182/blood.V104.11.1218.1218

Published: 2004

Journal Articles

Long-Range Enhancement of β-Globin Gene Expression Is Dependent on Gt Motifs Residing in the HS3 Core Element of the Locus Control Region.

Patrick A. Navas, PhD, Andrew B. Stergachis, Hadar H. Sheffer, Xin Ye, Mary Stafford, George Stamatoyannopoulos, MD

Blood (2004) 104 (11): 1222.

https://doi.org/10.1182/blood.V104.11.1222.1222

Published: 2004

Journal Articles

B Locus YAC Mice Carrying G Gene Promoter Mutations: Insights into the Mechanism of Action of the -175 HPFH Mutation.

Man Yu, MD, Xin Ye, MD, Hemei Han, BS, Mary Stafford, BS, Patrick A. Navas, PhD, Qiliang Li, PhD, George Stamatoyannopoulos, MD, PhD

Blood (2004) 104 (11): 1225.

https://doi.org/10.1182/blood.V104.11.1225.1225

Published: 2004

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In Vivo HSC Transduction and Selection Results in Long-Term, High-Level Expression of Human Gamma Globin in Peripheral Blood Erythrocytes of Mice

Introduction of Two Simultaneous Mutations By Genome Editing Greatly Enhances the Accumulation of the Endogenous Fetal Hemoglobin in Human Normal Erythroid Cells

Clinical-Scale Genome Editing of the Human BCL11A Erythroid Enhancer for Treatment of the Hemoglobinopathies

PDCD2 Knockdown Promoted Induced Erythroid Differentiation in TF-1 Cells

Plerixafor+G-CSF-Mobilized Blood From Thalassemic Mice Provides High Yields Of Long-Term Repopulating Cells With Enhanced Engrafting Capacity : Implications For Human Stem Cell Gene Therapy

Targeted Gene Modification In Hematopoietic Stem Cells: A Potential Treatment For Thalassemia and Sickle Cell Anemia

Talen-Mediated Knock Outs Of Cis and Trans Elements Potentially Involved In Globin Gene Switching

Hematopoietic Cell Mobilization for Gene Therapy of Adult Patients with Severe Beta-Thalassemia: The Challenge of Splenectomy and the Role of Plerixafor

Limitations of G-CSF Mobilization in Splenectomized Patients with Beta-Thalassemia Major: Implications for Thalassemia Gene Therapy.

Potent Induction of Human γ Globin Gene Expression by Largazole, a New Histone Deacetylase Inhibitor.

Chromatin Profiling of the Globin Loci of Human ES Cells and ES-Derived Erythroid Cells.

A Contigs Strategy of Southern Blot Hybridization: Screening for DNase I Hypersensitive Sites in the 200 Kb Region 5′ to the B-Globin Locus LCR.

Erythroid-Specific Intergenic Transcripts Originate from the 200 Kb Region 5′ to the LCR in Erythroleukemia and Human Primary Cells.

Long-Range Enhancement of β-Globin Gene Expression Is Dependent on Gt Motifs Residing in the HS3 Core Element of the Locus Control Region.

B Locus YAC Mice Carrying G Gene Promoter Mutations: Insights into the Mechanism of Action of the -175 HPFH Mutation.

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