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Gertjan L Kaspers
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Journal Articles

Acquired Resistance to Bortezomib in Human RPMI-8226 Multiple Myeloma Cells: Molecular Characterization, Cross-Resistance with Other Proteasome Inhibitors but Marked Sensitization to Glucocorticoids

Niels E Franke, MD, MSc, Gertjan L Kaspers, MD, PhD, Nynke van den Berg, Ina van Zantwijk, Katarina Vojtekova, MSc, Uzma Yaqub, BSc, Serge Smeets, MSc, Bauke Ylstra, PhD, Sonja Zweegman, MD, PhD, Gerrit Jansen, PhD, Jacqueline Cloos, PhD
Journal: Blood
Blood (2008) 112 (11): 2640.
https://doi.org/10.1182/blood.V112.11.2640.2640
Published: 2008
Journal Articles

Acquisition of Mutations in the PSMB5 Gene during Chronic Exposure of Human Acute Lymphoblastic Leukemia CCRF-CEM Cells to the Proteasome Inhibitor Bortezomib

Niels E Franke, MD, MSc, Ruud Oerlemans, MSc, Ina van Zantwijk, Katarina Vojtekova, MSc, Gertjan L Kaspers, MD, PhD, Gerrit Jansen, PhD, Jacqueline Cloos, PhD
Journal: Blood
Blood (2008) 112 (11): 2642.
https://doi.org/10.1182/blood.V112.11.2642.2642
Published: 2008
Journal Articles

Molecular basis of bortezomib resistance: proteasome subunit β5 ( PSMB5 ) gene mutation and overexpression of PSMB5 protein

Ruud Oerlemans, Niels E. Franke, Yehuda G. Assaraf, Jacqueline Cloos, Ina van Zantwijk, Celia R. Berkers, George L. Scheffer, Kabir Debipersad, Katharina Vojtekova, Clara Lemos, Joost W. van der Heijden, Bauke Ylstra, Godefridus J. Peters, Gertjan L. Kaspers, Ben A. C. Dijkmans, Rik J. Scheper, Gerrit Jansen
Journal: Blood
Blood (2008) 112 (6): 2489–2499.
https://doi.org/10.1182/blood-2007-08-104950
Published: 2008
Includes: Supplemental data