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Journal Articles

Leukemic Cell with a Novel Kinase Fusion Gene SPAG9-JAK2 Exhibits High Sensitivity to Ruxolitinib

Azusa Mayumi, MD, Toshihiro Tomii, MD, Toshihiko Imamura, MD PhD, Machiko Kawamura, MD, Hajime Hosoi, MD PhD

Blood (2019) 134 (Supplement_1): 5044.

https://doi.org/10.1182/blood-2019-126592

Published: 2019

Journal Articles

A Novel PAX5-KIDINS220 Fusion Protein Activates Multiple Signals Associated with Therapeutic Resistance

Takuyo Kanayama, MD, Toshihiko Imamura, MD PhD, Kenichi Sakamoto, MD PhD, Fumihiko Hayakawa, MD, PhD, Akihiko Tanizawa, MD PhD, Nobutaka Kiyokawa, MD PhD, Hajime Hosoi, MD PhD

Blood (2018) 132 (Supplement 1): 3928.

https://doi.org/10.1182/blood-2018-99-116022

Published: 2018

Journal Articles

Coagulation and Fibrinolysis Imbalance Demonstrated By Novel Simultaneous Thrombin and Plasmin Generation Assay during L-Asparaginase Treatment Phase of Induction Therapy in Pediatric Acute Lymphoblastic Leukemia

Takashi Ishihara, MD, Keiji Nogami, MD PhD, Satoshi Ochi, MD, Toshiaki Ishida, MD PhD, Yoshiyuki Kosaka, MD PhD, Akihisa Sawada, MD PhD, Masami Inoue, MD, Shinya Osone, MD PhD, Toshihiko Imamura, MD PhD, Hajime Hosoi, MD PhD, Midori Shima, MD PhD

Blood (2018) 132 (Supplement 1): 3972.

https://doi.org/10.1182/blood-2018-99-110411

Published: 2018

Journal Articles

Leukemic Cell Expressing a Novel Kinase Fusion Protein NCOR1-LYN Exhibits High Sensitivity to Dasatinib and Rapamycin

Toshihiro Tomii, MD, Toshihiko Imamura, MD PhD, Mio Yano, MD, Kenichi Sakamoto, MD PhD, Itaru Kato, Kuniaki Tanaka, MD, Takashi Mikami, MD, Makiko Morita, PhD, Souichi Adachi, MD PhD, Junko Takita, MD, PhD, Nobutaka Kiyokawa, MD PhD, Keizo Horibe, MD PhD, Hajime Hosoi, MD PhD

Blood (2018) 132 (Supplement 1): 1557.

https://doi.org/10.1182/blood-2018-99-111612

Published: 2018

Journal Articles

Analysis of Copy Number Abnormalities of 86 Acute Lymphoblastic Leukemia Cell Lines Based on the Genetic Subtypes

Chihiro Tomoyasu, MD, Toshihiko Imamura, MD, Mio Yano, MD, Daisuke Asai, MD, Meixian Huang, MD, Hiroaki Goto, MD PhD, Akira Shimada, MD PhD, Takeshi Inukai, MD PhD, Kanji Sugita, MD PhD, Hajime Hosoi, MD

Blood (2015) 126 (23): 1424.

https://doi.org/10.1182/blood.V126.23.1424.1424

Published: 2015

Journal Articles

Clinical Significance of LNK (SH2B3) Expression in Pediatric B Cell Precursor Acute Lymphoblastic Leukemia

Mio Yano, MD, Toshihiko Imamura, MD, Kenichi Sakamoto, MD, Daisuke Asai, MD, Gen Kano, MD, Hajime Hosoi, MD, Takao Deguchi, MD, Yoshiko Hashii, MD, Mikiya Endo, MD, Atsushi Sato, MD, Hirohide Kawasaki, MD, Yoshiyuki Kosaka, MD, Koji Kato, MDPhD, Hiroki Hori, MD, Keiko Yumura, MD, Junichi Hara, MD, Megumi Oda, MD, Stephen T. Oh, MD PhD, Keizo Horibe, MD

Blood (2014) 124 (21): 3772.

https://doi.org/10.1182/blood.V124.21.3772.3772

Published: 2014

Journal Articles

MLL-AF9 Positive Acute Myeloid Leukemia Cells Are Sensitive To All-Trans Retinoic Acid

Kenichi Sakamoto, MD, Toshihiko Imamura, MD, Mio Yano, MD, Hideki Yoshida, MD, Atsushi Fujiki, MD, Yoshifumi Hirashima, MD, Hajime Hosoi, MD

Blood (2013) 122 (21): 3827.

https://doi.org/10.1182/blood.V122.21.3827.3827

Published: 2013

Journal Articles

ABT-737 Restores Prednisolone Sensitivity In Early T-Cell Precursor Acute Lymphoblastic Leukemia With High MEF2C Expression

Sachiko Goto, MD, Toshihiko Imamura, MD, Atsushi Fujiki, MD, Takuya Nakatani, MD, Yoshifumi Hirashima, MD, Shinichi Tamura, MD, Shinya Osone, MD, Hiroyuki Ishida, MD, Akira Morimoto, MD, Hiroshi Kuroda, MD, Shigeyoshi Hibi, MD, Shinsaku Imashuku, MD, Hajime Hosoi, MD

Blood (2013) 122 (21): 3830.

https://doi.org/10.1182/blood.V122.21.3830.3830

Published: 2013

Journal Articles

LSD1 Inhibitor Activates Retinoic Acid Pathway in MLL Fusion Positive Acute Myeloid Leukemia

Mio Yano, MD, Toshihiko Imamura, MD, Kenichi Sakamoto, MD, Hideki Yoshida, MD, Atsushi Fujiki, MD, Yoshifumi Hirashima, MD, Hiroyuki Ishida, MD, Hajime Hosoi, MD

Blood (2012) 120 (21): 1345.

https://doi.org/10.1182/blood.V120.21.1345.1345

Published: 2012

Journal Articles

Specific MLL Fusion Partners Affect the Sensitivity of Human and Murine Leukemic Cell Lines to Demethylating Agents

Atsushi Fujiki, MD, Toshihiko Imamura, MD, PhD, Hideki Yoshida, MD, Yoshifumi Hirashima, MD, Mitsuru Miyachi, MD, PhD, Shigeki Yagyu, MD, PhD, Kanji Sugita, MD, PhD, Hajime Hosoi, MD, PhD

Blood (2010) 116 (21): 2158.

https://doi.org/10.1182/blood.V116.21.2158.2158

Published: 2010

Journal Articles

RAD001, An Inhibitor of mTOR, Enhances Monocytic Differentiation Induced by ATRA through Phosphorylation of C/EBPα In AML Cell Lines

Hideki Yoshida, MD, Toshihiko Imamura, MD, PhD, Atsushi Fujiki, MD, Yoshifumi Hirashima, MD, Mitsuru Miyachi, MD, PhD, Kanji Sugita, MD, PhD, Hajime Hosoi, MD, PhD

Blood (2010) 116 (21): 2152.

https://doi.org/10.1182/blood.V116.21.2152.2152

Published: 2010

NARROW

Leukemic Cell with a Novel Kinase Fusion Gene SPAG9-JAK2 Exhibits High Sensitivity to Ruxolitinib

A Novel PAX5-KIDINS220 Fusion Protein Activates Multiple Signals Associated with Therapeutic Resistance

Coagulation and Fibrinolysis Imbalance Demonstrated By Novel Simultaneous Thrombin and Plasmin Generation Assay during L-Asparaginase Treatment Phase of Induction Therapy in Pediatric Acute Lymphoblastic Leukemia

Leukemic Cell Expressing a Novel Kinase Fusion Protein NCOR1-LYN Exhibits High Sensitivity to Dasatinib and Rapamycin

Analysis of Copy Number Abnormalities of 86 Acute Lymphoblastic Leukemia Cell Lines Based on the Genetic Subtypes

Clinical Significance of LNK (SH2B3) Expression in Pediatric B Cell Precursor Acute Lymphoblastic Leukemia

MLL-AF9 Positive Acute Myeloid Leukemia Cells Are Sensitive To All-Trans Retinoic Acid

ABT-737 Restores Prednisolone Sensitivity In Early T-Cell Precursor Acute Lymphoblastic Leukemia With High MEF2C Expression

LSD1 Inhibitor Activates Retinoic Acid Pathway in MLL Fusion Positive Acute Myeloid Leukemia

Specific MLL Fusion Partners Affect the Sensitivity of Human and Murine Leukemic Cell Lines to Demethylating Agents

RAD001, An Inhibitor of mTOR, Enhances Monocytic Differentiation Induced by ATRA through Phosphorylation of C/EBPα In AML Cell Lines

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American Society of Hematology

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ASH Publications

American Society of Hematology

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