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Journal Articles

GATA1s Exerts Fetal Stage-Specific Oncogenic Effects in Human Hematopoietic Stem and Progenitor Cells

Aliaksandra Maroz, Ben Van Handel, Hanna Mikkola, MD, PhD, Jennifer Schoenning, Dirk Reinhardt, MD, PhD, Jan-Henning Klusmann, MD
Journal: Blood
Blood (2011) 118 (21): 2355.
https://doi.org/10.1182/blood.V118.21.2355.2355
Published: 2011
Journal Articles

Latent Cardiogenic Potential in Endocardium and Hemogenic Endothelium Revealed in the Absence of Scl/tal1

Amelie Montel-Hagen, PhD, Ben Van Handel, Roberto Ferrari, Rajkumar Sasidharan, PhD, Tonis Org, Kees Boogerd, Haruko Nakano, Jian Zhou, Xinmin Li, Matteo Pellegrini, Stuart H. Orkin, MD, Austin Nakano, Siavash Kurdistani, M.D., Sylvia Evans, Hanna Mikkola, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2362.
https://doi.org/10.1182/blood.V118.21.2362.2362
Published: 2011
Journal Articles

Cycling Toward Leukemia Stem Cell Elimination Wtih a Selective Sonic Hedgehog Antagonist,

Alice Y Shih, BS, Annelie Schairer, Ph.D., Christian L Barrett, Ph.D., Ifat Geron, MSc, Angela C Court Recart, BS, MS, Daniel Goff, BS, Sacha Prashad, Jerry Wu, PharmD, Qingfei Jiang, PhD, Jason Gotlib, MD, MS, Larisa Balaian, Ph.D., Mark D. Minden, MD, PhD, Heather Leu, BS, Russell Wall, BS, Wenxue Ma, M.D., Ph.D., Kamran Shazand, PhD, John D McPherson, PhD, Steven M. Kornblau, MD, Ida Deichaite, PhD, Minya Pu, PhD, Lei Bao, PhD, Giovanni Martinelli, MD, Tannishtha Reya, PhD, Sheldon R Morris, MD, MPH, Todd VanArsdale, PhD, Thomas J Hudson, MD, Karen Messer, PhD, Hanna Mikkola, MD, PhD, Wendy J. Levin, MD, MS, Kelly A Frazer, Ph.D., Anil Sadarangani, Ph.D., Catriona Jamieson, MD, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 3776.
https://doi.org/10.1182/blood.V118.21.3776.3776
Published: 2011
Journal Articles

GPI80 Distinguishes Transplantable Human Fetal Hematopoietic Stem Cells From Multipotential Progenitors

Sacha Prashad, Catherine Yao, Mattias Magnusson, PhD, Rajkumar Sasidharan, PhD, Hanna Mikkola, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 1280.
https://doi.org/10.1182/blood.V118.21.1280.1280
Published: 2011
Journal Articles

Origin of Hematopoietic Stem Cells

Hanna Mikkola, MD, PhD
Journal: Blood
Blood (2010) 116 (21): SCI-40.
https://doi.org/10.1182/blood.V116.21.SCI-40.SCI-40
Published: 2010
Journal Articles

Essential Function of PDGF-B Signaling In the Placental Microenvironment In Protecting Hematopoietic Progenitors From Erythroid Differentiation.

Akanksha Chhabra, Andrew J Lechner, Asha Acharya, Masaya Ueno, PhD, Ben Van Handel, Michelle Tallquist, PhD, Hanna Mikkola, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1559.
https://doi.org/10.1182/blood.V116.21.1559.1559
Published: 2010
Journal Articles

Specification and Maintenance of the Scl Induced Hematopoietic Stem Cell Fate.

Laurraine-Marcelle Gereige, Roberto Ferrari, PhD, Amelie Montel-Hagen, PhD, Matteo Pellegrini, Ph.D., Xinmin Li, PhD, Siavash Kurdistani, MD, Hanna Mikkola, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1504.
https://doi.org/10.1182/blood.V114.22.1504.1504
Published: 2009
Journal Articles

Blood Flow Is Required for the Release of Hematopoietic Stem- and Progenitor Cells From Hemogenic Endothelium in the Placenta.

Katrin E Rhodes, Ben Van Handel, Michele Wang, Yanling Wang, Akanksha Chhabra, Hanna Mikkola, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 698.
https://doi.org/10.1182/blood.V114.22.698.698
Published: 2009
Journal Articles

The First Trimester Human Placenta Is An Embryonic Hematopoietic Organ with An Unexpected Function in Primitive Erythroid Maturation.

Ben Van Handel, Sacha Prashad, Andy Huang, MD, Nargess Hassanzedeh-Kiabi, Mattias Magnusson, PhD, Boriana Atanassova, Eija Hamalainen, Angela Chen, MD, Hanna Mikkola, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1508.
https://doi.org/10.1182/blood.V114.22.1508.1508
Published: 2009
Journal Articles

UCP2 Modulates Cell Proliferation through the MAPK/ERK Pathway during Erythropoiesis and Has No Effect on Heme Biosynthesis

Alvaro A Elorza, PhD, Brigham B Hyde, Hanna Mikkola, MD, PhD, Sheila Collins, PhD, Orian S Shirihai, MD/PhD
Journal: Blood
Blood (2008) 112 (11): 5372.
https://doi.org/10.1182/blood.V112.11.5372.5372
Published: 2008
Journal Articles

Mef2C Is a Lineage-Restricted Target Gene of Scl/Tal1 and Regulates Megakaryopoiesis and B-Cell Homeostasis

Katrin E Rhodes, Christos Gekas, Laurraine Gereige, Hildur Helgadottir, Roberto Ferrari, Siavash Kurdistani, Encarnacion Montecino-Rodriguez, Rhonda Basel-Duby, Eric Olson, Stuart H. Orkin, MD, Matteo Pellegrini, Ph.D., Hanna Mikkola, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 278.
https://doi.org/10.1182/blood.V112.11.278.278
Published: 2008
Journal Articles

Recreating a Human Hematopoietic Stem Cell Niche in Vitro by Unique Stroma Cells from the First Trimester Human Placenta and Fetal Liver

Mattias Magnusson, PhD, Melissa Romero, Sacha Prashad, Ben Van Handel, Suvi Aivio, Andy Huang, MD, Matteo Pellegrini, Ph.D., Hanna Mikkola, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 3568.
https://doi.org/10.1182/blood.V112.11.3568.3568
Published: 2008
Journal Articles

Knockdown of ABCme Impairs Heme Biosynthesis as Revealed by Integrating of RNAi and the LiveCell ® Array.

Sarah E. Haigh, PhD, Alvaro A. Elorza, PhD, Israel Biran, PhD, Naomi Zurgil, PhD, Motti Deutsch, PhD, Hanna Mikkola, MD/PhD, Orian S. Shirihai, MD/PhD
Journal: Blood
Blood (2005) 106 (11): 3732.
https://doi.org/10.1182/blood.V106.11.3732.3732
Published: 2005