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Heikki Kuusanmäki, MSc
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Journal Articles

Single-Cell Drug Profiling Reveals Maturation Stage-Dependent Drug Responses in AML

Heikki Kuusanmäki, MSc, Maija Leppä, BSc, Mika Kontro, MD, Olli Dufva, BSc, Debashish Deb, MSc, Bhagwan Yadav, PhD, Satu Mustjoki, MDPhD, Kimmo Porkka, MD PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3821.
https://doi.org/10.1182/blood.V130.Suppl_1.3821.3821
Published: 2017
Journal Articles

In Silico and Ex Vivo Drug Screening Identifies Dasatinib as a Potential Targeted Therapy for T-ALL

Saara Laukkanen, Petri Pölönen, Toni Grönroos, Heikki Kuusanmäki, MSc, Caroline A Heckman, PhD, Mika Kontro, Merja Heinäniemi, Olli Lohi
Journal: Blood
Blood (2016) 128 (22): 4029.
https://doi.org/10.1182/blood.V128.22.4029.4029
Published: 2016
Journal Articles

A High-Throughput Biology Approach to Identify Novel Therapies Specifically Targeting AML Blasts and Leukemic Stem Cells

Heikki Kuusanmäki, MSc, Aino Maija Leppä, BSc, Debashish Deb, BSc, Caroline A Heckman, PhD
Journal: Blood
Blood (2016) 128 (22): 2755.
https://doi.org/10.1182/blood.V128.22.2755.2755
Published: 2016
Journal Articles

Mutational Landscape of Aggressive Natural Killer Cell Leukemia and Drug Sensitivity Profiling Reveal Therapeutic Options in Natural Killer Cell Malignancies

Olli Dufva, Matti Kankainen, PhD, Tiina Kelkka, PhD, Shady Adnan Awad, MD, Nodoka Sekiguchi, MD, Bhagwan Yadav, MSc, Samuli Eldfors, MSc, Heikki Kuusanmäki, MSc, Emma I Andersson, MSc, Disha Malani, MSc, Paavo Pietarinen, MSc, Leena Saikko, Panu E Kovanen, MD PhD, Junji Suzumiya, MD PhD, Ritsuro Suzuki, MD PhD, Young Hyeh Ko, MD, Won Seog Kim, MD PhD, Shih-Sung Chuang, MD, Thomas P. Loughran, Jr., MD, Wing Chung Chan, MD, Koichi Ohshima, MD PhD, Tero Aittokallio, Fumihiro Ishida, MD PhD, Satu Mustjoki, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2921.
https://doi.org/10.1182/blood.V128.22.2921.2921
Published: 2016
Journal Articles

Identification of Optimized Compound Combinations for the Treatment of NUP98-NSD1+ AML

Jarno Kivioja, MSc, Angeliki Thanasopoulou, PhD, Mika Kontro, MD, Bhagwan Yadav, MSc, Muntasir Mamun Majumder, MSc, Heikki Kuusanmäki, MSc, Alun Parsons, MSc, Kimmo Porkka, MD PhD, Juerg Schwaller, MD, Caroline A Heckman, PhD
Journal: Blood
Blood (2016) 128 (22): 4711.
https://doi.org/10.1182/blood.V128.22.4711.4711
Published: 2016
Journal Articles

Stratification of Multiple Myeloma Patients Based on Ex Vivo Drug Sensitivity and Identification of New Treatments for Patients with High-Risk Relapsed/Refractory Disease

Muntasir Mamun Majumder, MSc,MPharm, Raija Silvennoinen, MD, Pekka Anttila, MD, David Tamborero, PhD, Samuli Eldfors, MSc, Juha Lievonen, MD, Riikka J Karjalainen, Heikki Kuusanmäki, MSc, Alun Parsons, Minna Suvela, Kimmo Porkka, MD PhD, Caroline Heckman
Journal: Blood
Blood (2015) 126 (23): 3006.
https://doi.org/10.1182/blood.V126.23.3006.3006
Published: 2015
Journal Articles

Exome Sequencing of Aggressive Natural Killer Cell Leukemia and Drug Profiling Highlight Candidate Driver Pathways in Malignant Natural Killer Cells

Olli Dufva, BMed, Tiina Kelkka, PhD, Shady Awad, MD, Nodoka Sekiguchi, MD, Heikki Kuusanmäki, MSc, Emma I Andersson, MSc, Samuli Eldfors, MSc, Disha Malani, MSc, Paavo Pietarinen, MSc, Leena Saikko, Panu E Kovanen, MD PhD, Junji Suzumiya, MD PhD, Koichi Ohshima, MD PhD, Young Hyeh Ko, MD, Won Seog Kim, MD PhD, Shih-Sung Chuang, MD, Thomas P. Loughran, Jr., MD, Wing C Chan, MD, Fumihiro Ishida, MD PhD, Satu Mustjoki, MD PhD
Journal: Blood
Blood (2015) 126 (23): 700.
https://doi.org/10.1182/blood.V126.23.700.700
Published: 2015
Journal Articles

Identification of Dual PI3K/mTOR and BCL2 Inhibitors for the Treatment of High Risk Multiple Myeloma

Raija Silvennoinen, MD, Muntasir Mamun Majumder, MSc,BPharm, David Tamborero, PhD, Pekka Anttila, MD, Samuli Eldfors, MSc, Riikka Karjalainen, MSc, Heikki Kuusanmäki, MSc, Juha Lievonen, MD, Alun Parsons, MSc, Minna Suvela, Marjaana Säily, MDPhD, Kimmo Porkka, MD PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2014) 124 (21): 646.
https://doi.org/10.1182/blood.V124.21.646.646
Published: 2014
Journal Articles

Integration of Ex Vivo Drug Testing and in-Depth Molecular Profiling Reveals Oncogenic Signaling Pathways and Novel Therapeutic Strategies for Multiple Myeloma

Muntasir Mamun Majumder, MSc,BPharm, Raija Silvennoinen, MD, Pekka Antilla, David Tamborero, Samuli Eldfors, MSc, Riikka Karjalainen, MSc, Heikki Kuusanmäki, MSc, Juha Lievonen, MD, Alun Parsons, MSc, Minna Suvela, Marjanna Säily, Bhagwan Yadav, MSc, Krister Wennerberg, PhD, Olli Kallioniemi, MD PhD, Kimmo Porkka, MD PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2014) 124 (21): 2046.
https://doi.org/10.1182/blood.V124.21.2046.2046
Published: 2014
Journal Articles

Drug Sensitivity Profiling Identifies Drugs for Targeting Constitutively Active Mutant STAT3 and Mutant STAT5B Positive Malignancies

Heikki Kuusanmäki, MSc, Hanna Rajala, MD PhD, Arjan van Adrichem, Muntasir Mamun Majumder, MSc,BPharm, Emma I Andersson, MSc, Krister Wennerberg, PhD, Satu Mustjoki, MDPhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2014) 124 (21): 1771.
https://doi.org/10.1182/blood.V124.21.1771.1771
Published: 2014
Journal Articles

Identification of Novel Therapeutic Strategies for NUP98-NSD1-Positive AML By Drug Sensitivity Profiling

Jarno Kivioja, MSc, Mika Kontro, MD, Angeliki Thanasopoulou, PhD, Muntasir Mamun Majumder, MSc,BPharm, Bhagwan Yadav, MSc, Heikki Kuusanmäki, MSc, Alun Parsons, MSc, Juerg Schwaller, MD, Kimmo Porkka, MD PhD, Caroline A Heckman, PhD
Journal: Blood
Blood (2014) 124 (21): 2160.
https://doi.org/10.1182/blood.V124.21.2160.2160
Published: 2014
Journal Articles

Novel Activating STAT5B Mutations As Drivers Of T-ALL

Mika Kontro, MD, Heikki Kuusanmäki, MSc, Samuli Eldfors, MSc, Tea Pemovska, MSc, Hanna L M Rajala, MD, Henrik Edgren, PhD, Pekka Ellonen, MSc, Sonja Lagström, MSc, Tuija Lundán, PhD, Olli Kallioniemi, MD, PhD, Satu Mustjoki, MD, PhD, Kimmo Porkka, MD, PhD, Caroline Heckman, PhD
Journal: Blood
Blood (2013) 122 (21): 3863.
https://doi.org/10.1182/blood.V122.21.3863.3863
Published: 2013