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Heiko Rühl
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Journal Articles

Increased Activated Protein C Response Rates to Thrombin Formation in Asymptomatic Factor V Leiden Carriers Are Driven By the Endothelium

Nadine Schwarz, Jens Müller, Hannah Lisa McRae, Sara Reda, Johannes Oldenburg, Bernd Pötzsch, Heiko Rühl
Journal: Blood
Blood (2023) 142 (Supplement 1): 3939.
https://doi.org/10.1182/blood-2023-180732
Published: 2023
Journal Articles

Evaluation of an Explainable Tree-Based AI Model for Thrombophilia Diagnosis and Thrombosis Risk Stratification

Hannah L McRae, Fabian Kahl, Maximilian Kapsecker, Heiko Rühl, Stephan M Jonas, Bernd Pötzsch
Journal: Blood
Blood (2023) 142 (Supplement 1): 2300.
https://doi.org/10.1182/blood-2023-190920
Published: 2023
Journal Articles

Patients with Familial Thrombophilia of Unknown Origin Show Low APC Response to In Vivo Thrombin Formation in Stimulated Hemostasis Activity Pattern Evaluation (SHAPE)

Heiko Rühl, MD, Sara Reda, MD, Franziska Isabelle Winterhagen, Christina Berens, MD, Jens Müller, Johannes Oldenburg, Bernd Pötzsch, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3647.
https://doi.org/10.1182/blood-2019-124507
Published: 2019
Journal Articles

Circulating Plasminogen Activator Inhibitor-1 (PAI-1) Is Reduced By In Vivo Thrombin Generation and Subsequent Formation of Activated Protein C (APC)

Sara Reda, MD, Franziska Isabelle Winterhagen, Christina Berens, MD, Jens Müller, Johannes Oldenburg, Bernd Pötzsch, MD, Heiko Rühl, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2389.
https://doi.org/10.1182/blood-2019-124731
Published: 2019
Journal Articles

A Novel Method for Flow Cytometric Quantification of Human Platelet Membrane Glycoproteins in Citrated Whole Blood

Christina Berens, MD, Jens Müller, Heiko Rühl, MD, Johannes Oldenburg, Bernd Pötzsch, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2367.
https://doi.org/10.1182/blood-2019-124646
Published: 2019
Journal Articles

Platelet-Dependent Thrombin Generation Induced By ADP or Activated Factor X Does Not Contribute to Increased In Vivo Thrombin Formation in Myeloproliferative Neoplasms

Christina Berens, Heiko Rühl, MD, Jens Müller, Johannes Oldenburg, MD PhD, Peter Brossart, MD, Dominik Wolf, MD, Bernd Pötzsch
Journal: Blood
Blood (2018) 132 (Supplement 1): 4336.
https://doi.org/10.1182/blood-2018-99-118487
Published: 2018
Journal Articles

The Variable Clinical Expressivity of Factor V Leiden, but Not of Prothrombin G20210A, Correlates with the Extent of the APC Response to In Vivo Thrombin Formation

Heiko Rühl, MD, Christina Berens, Sara Reda, Franziska Isabelle Winterhagen, Jens Müller, Johannes Oldenburg, MD, Peter Hanfland, Bernd Pötzsch
Journal: Blood
Blood (2018) 132 (Supplement 1): 1221.
https://doi.org/10.1182/blood-2018-99-115949
Published: 2018
Journal Articles

In vivo thrombin generation and subsequent APC formation are increased in factor V Leiden carriers

Heiko Rühl, Franziska Isabelle Winterhagen, Christina Berens, Jens Müller, Johannes Oldenburg, Bernd Pötzsch
Journal: Blood
Blood (2018) 131 (13): 1489–1492.
https://doi.org/10.1182/blood-2017-12-823831
Published: 2018
Includes: Supplemental data
Journal Articles

Pattern of Coagulation Activation in Patients with Myeloproliferative Neoplasms

Christina Berens, Heiko Rühl, Maria Vonnahme, Jens Müller, Johannes Oldenburg, Peter Brossart, Dominik Wolf, Bernd Pötzsch
Journal: Blood
Blood (2017) 130 (Supplement 1): 3707.
https://doi.org/10.1182/blood.V130.Suppl_1.3707.3707
Published: 2017
Journal Articles

Evaluation of the Thrombophilic Response to rFVIIa-Induced Hemostasis Activation in Factor V Leiden Carriers By Monitoring of Activated Protein C (APC) In Vivo

Heiko Rühl, Christina Berens, Franziska Isabelle Winterhagen, Jens Müller, Johannes Oldenburg, Bernd Pötzsch
Journal: Blood
Blood (2017) 130 (Supplement 1): 461.
https://doi.org/10.1182/blood.V130.Suppl_1.461.461
Published: 2017
Journal Articles

Evidence of Thrombin-Independent Generation of Activated Protein C

Heiko Rühl, MD, Janine Rossa, Christina Berens, MD, Anna Winterhagen, Johannes Oldenburg, Prof, Jens Müller, PhD, Bernd Pötzsch, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2568.
https://doi.org/10.1182/blood.V128.22.2568.2568
Published: 2016
Journal Articles

The Serpins C1-Inhibitor and Antithrombin Synergistically Regulate the Catalytic Life of Activated Factor XI in Healthy Individuals and Thrombophilic Patients

Heiko Rühl, MD, Jens Müller, PhD, Johannes Oldenburg, MD PhD, Bernd Pötzsch, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1475.
https://doi.org/10.1182/blood.V124.21.1475.1475
Published: 2014