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Journal Articles

PU.1-Induced IRF4 Down-Regulation and Subsequent IRF7 up-Regulation in Myeloma Cells

Niina Ueno, MD, Shikiko Ueno, MD PhD, Shinya Endo, MD, Nao Nishimura, MD, Hiro Tatetsu, MD PhD, Shinya Hirata, MD PhD, Hiroaki Mitsuya, MD PhD, Yutaka Okuno, MD PhD

Blood (2015) 126 (23): 2957.

https://doi.org/10.1182/blood.V126.23.2957.2957

Published: 2015

Journal Articles

Conditional Knockout of Sfpi1 in Post GC B and Plasma Cells Induces B Cell Lymphoma and Plasma Cell Neoplasm

Shinya Endo, MD, Hiromichi Yuki, MD PhD, Yoshihiro Komohara, MD PhD, Shikiko Ueno, MD PhD, Nao Nishimura, MD, Niina Ueno, MD, Hiro Tatetsu, MD PhD, Motohiro Takeya, MD PhD, Hiroyuki Hata, MD PhD, Seiji Okada, MD PhD, Daniel G. Tenen, MD, Hiroaki Mitsuya, MD PhD, Yutaka Okuno, MD PhD

Blood (2014) 124 (21): 29.

https://doi.org/10.1182/blood.V124.21.29.29

Published: 2014

Journal Articles

Deposition of Lambda Chain Constant Region within AL-Amyloid Lesion

Hiroyuki Hata, MD PhD, Masayoshi Tasaki, Konen Obayashi, MD PhD, Taro Yamashita, MD PhD, Yukio Ando, MD PhD, Shinya Endo, MD, Nao Nishimura, MD, Yutaka Okuno, MD PhD, Shiho Fujiwara, MD PhD, Naoko Wada, MD, Eri Fujii, Kennichi Iyama, MD PhD, Hiroaki Mitsuya, MD PhD

Blood (2014) 124 (21): 3348.

https://doi.org/10.1182/blood.V124.21.3348.3348

Published: 2014

Journal Articles

Xenograft Models of Multiple Myeloma Reveal That PU.1 Serves As a Tumor Suppressor for Multiple Myeloma

Nao Nishimura, MD, Shinya Endo, MD, Niina Ueno, MD, Shikiko Ueno, MD PhD, Hiromichi Yuki, MD PhD, Hiroyuki Hata, MD PhD, Hiroaki Mitsuya, MD PhD, Yutaka Okuno, MD PhD

Blood (2014) 124 (21): 2047.

https://doi.org/10.1182/blood.V124.21.2047.2047

Published: 2014

Journal Articles

A Small Molecule, Shikonin, Dually Functions As a Proteasome Inhibitor and a Necroptosis Inducer In Multiple Myeloma Cells

Naoko Wada, MD, Yawara Kawano, MD, PhD, Shiho Fujiwara, MD, Yoshitaka Kikukawa, MD, PhD, Yutaka Okuno, MD, PhD, Hiroaki Mitsuya, MD, PhD, Hiroyuki Hata, MD, PhD

Blood (2013) 122 (21): 3172.

https://doi.org/10.1182/blood.V122.21.3172.3172

Published: 2013

Journal Articles

IDH1 and IDH2 Mutations Confer An Adverse Effect In Patients With Acute Myeloid Leukemia Lacking The NPM1 Mutation

Shunichiro Yamaguchi, MD, Eisaku Iwanaga, MD, PhD, Kenji Tokunaga, MD, Tomoko Nanri, MD, PhD, Taizo Shimomura, MD, PhD, Hitoshi Suzushima, MD, PhD, Yutaka Okuno, MD, PhD, Hiroaki Mitsuya, MD, PhD, Norio Asou, MD, PhD

Blood (2013) 122 (21): 4977.

https://doi.org/10.1182/blood.V122.21.4977.4977

Published: 2013

Journal Articles

Accumulation Of Gene Alterations Of TP53 , Crebbp and IKZF1 Is a Prognostic Factor In Adult Acute Lymphoblastic Leukemia

Kenji Tokunaga, MD, Shunichro Yamaguchi, MD, Taizo Shimomura, MD, PhD, Hitoshi Suzushima, MD, PhD, Yutaka Okuno, MD, PhD, Hiroaki Mitsuya, MD, PhD, Norio Asou, MD, PhD

Blood (2013) 122 (21): 1386.

https://doi.org/10.1182/blood.V122.21.1386.1386

Published: 2013

Journal Articles

Lactate Is a Crucial Energy Source For Multiple Myeloma (MM) Cells In Bone Marrow Microenvironment

Shiho Fujiwara, MD, Naoko Wada, MD, Yawara Kawano, MD, PhD, Yoshitaka Kikukawa, MD PhD, Hiroaki Mitsuya, MD PhD, Hiroyuki Hata, MD, PhD

Blood (2013) 122 (21): 3109.

https://doi.org/10.1182/blood.V122.21.3109.3109

Published: 2013

Journal Articles

Hypoxia Reduces CD138 Expression and Induces Immature Phenotype in Myeloma Cells

Yawara Kawano, MD, Shiho Fujiwara, MD, Naoko Wada, MD, Hiromichi Yuki, MD, Hiroaki Mitsuya, MD, PhD, Hiroyuki Hata, MD, PhD

Blood (2012) 120 (21): 3956.

https://doi.org/10.1182/blood.V120.21.3956.3956

Published: 2012

Journal Articles

IDH2 Mutations Have An Unfavorable Impact in Elderly Patients with Acute Myeloid Leukemia

Shunichro Yamaguchi, MD, Eisaku Iwanaga, MD, Kenji Tokunaga, MD, Tomoko Nanri, MD, PhD, Hitoshi Suzushima, MD, PhD, Taizo Shimomura, MD, PhD, Hiroaki Mitsuya, MD, PhD, Norio Asou, MD, PhD

Blood (2011) 118 (21): 2519.

https://doi.org/10.1182/blood.V118.21.2519.2519

Published: 2011

Journal Articles

Decreased CD138 Expression in Myeloma Cells: A Potential Indicator of Poor Prognosis and Aberrant Differentiation,

Yawara Kawano, MD, Shiho Fujiwara, MD, Hiromichi Yuki, MD, Hiro Tatetsu, MD, PhD, Hiroshi Yamasaki, MD, PhD, Akira Sakai, MD, PhD, Yutaka Okuno, MD, PhD, Hiroaki Mitsuya, MD, PhD, Hiroyuki Hata, MD, PhD

Blood (2011) 118 (21): 3939.

https://doi.org/10.1182/blood.V118.21.3939.3939

Published: 2011

Journal Articles

Aerobic Glycolysis: A Possible Target for Treating Multiple Myeloma (MM) with High Serum LDH Levels

Shiho Fujiwara, MD, Yawara Kawano, MD, Hiromichi Yuki, MD, Yutaka Okuno, MD, PhD, Kisato Nosaka, MD, PhD, Hiroaki Mitsuya, MD, PhD, Hiroyuki Hata, MD, PhD

Blood (2011) 118 (21): 1799.

https://doi.org/10.1182/blood.V118.21.1799.1799

Published: 2011

Journal Articles

Characteristics of Chronic-Phase CML Patients Having Durable Cytogenetic Response to Low-Dose Imatinib

Tatsuya Kawaguchi, MD, PhD, Akinobu Hamada, PhD, Reiko Nakashima, Kentaro Horikawa, MD, PhD, Sonoko Ishihara, MD, PhD, Hideyuki Saito, PhD, Hiroaki Mitsuya, MD, PhD

Blood (2008) 112 (11): 3218.

https://doi.org/10.1182/blood.V112.11.3218.3218

Published: 2008

Journal Articles

A JAK2-V617F Activating Mutation in Addition to C-KIT and FLT3 Mutations Is Associated with Clinical Outcome in Patients with t(8;21)(q22;q22;) Acute Myeloid Leukemia.

Tomoko Nanri, MD, PhD, Eisaku Iwanaga, MD, Naofumi Matsuno, MD, PhD, Toshiro Kawakita, MD, Hitoshi Suzushima, MD, PhD, Fumio Kawano, MD, PhD, Hiroaki Mitsuya, MD, PhD, Norio Asou, MD, PhD

Blood (2007) 110 (11): 3492.

https://doi.org/10.1182/blood.V110.11.3492.3492

Published: 2007

Journal Articles

Clarithromicin Induces Autophagy in Myeloma Cells.

Miki Nakamura, MD, PhD, Takahiro Kamimoto, PhD, Tamotsu Yoshimori, PhD, Hiroaki Mitsuya, MD PhD, Hiroyuki Hata, MD PhD

Blood (2006) 108 (11): 3509.

https://doi.org/10.1182/blood.V108.11.3509.3509

Published: 2006

Journal Articles

Identification of Hepatic Progenitors Having No Hematopoietic Potential in Murine Bone Marrow.

Yasuhiro Yamada, MD, PhD, Hirosada Miyake, MD, Eishi Nishimoto, MD, Hiroaki Mitsuya, MD, PhD, Yuji Yonemura, MD, PhD

Blood (2006) 108 (11): 1684.

https://doi.org/10.1182/blood.V108.11.1684.1684

Published: 2006

Journal Articles

Kigamicin Induces Necrosis to Human Myeloma Cells by Disruption of Cell Cycle Regulation.

Miki Nakamura, MD, PhD, Hiroyasu Esumi, MD PhD, Jie Lu, PhD, Hiroaki Mitsuya, MD PhD, Hiroyuki Hata, MD PhD

Blood (2006) 108 (11): 5017.

https://doi.org/10.1182/blood.V108.11.5017.5017

Published: 2006

Journal Articles

Familial Acute Myeloblastic Leukemia with a Dominant Negative Mutation in the CEBPA Gene.

Tomoko Nanri, MD, Toshiro Kawakita, MD, Koyu Hoshino, MD, PhD, Hiroaki Mitsuya, MD, PhD, Norio Asou, MD, PhD, Naokuni Uike, MD

Blood (2005) 106 (11): 4564.

https://doi.org/10.1182/blood.V106.11.4564.4564

Published: 2005

Journal Articles

Hepatogenic Potential of Stem Cells and Lymphoid Precursors.

Yasuhiro Yamada, MD, Hirosada Miyake, MD, Eishi Nishimoto, MD, Hiroaki Mitsuya, MD, PhD, Yuji Yonemura, MD, PhD

Blood (2005) 106 (11): 1696.

https://doi.org/10.1182/blood.V106.11.1696.1696

Published: 2005

Journal Articles

Appearance of Stress-Inducible Membrane Proteins ULBP on Blood Cells of Patients with PNH, Aplastic Anemia, and MDS: Possible Implication of ULBP in Immune-Mediated Marrow Injury.

Nobuyoshi Hanaoka, MD, Kentaro Horikawa, MD, PhD, Yasuchika Tsuzuki, MD, Shoichi Nagakura, MD, PhD, Sonoko Ishihara, MD, PhD, Hiroaki Mitsuya, MD, PhD, Hideki Nakakuma, MD, PhD, Tatsuya Kawaguchi, MD, PhD

Blood (2005) 106 (11): 1041.

https://doi.org/10.1182/blood.V106.11.1041.1041

Published: 2005

NARROW

PU.1-Induced IRF4 Down-Regulation and Subsequent IRF7 up-Regulation in Myeloma Cells

Conditional Knockout of Sfpi1 in Post GC B and Plasma Cells Induces B Cell Lymphoma and Plasma Cell Neoplasm

Deposition of Lambda Chain Constant Region within AL-Amyloid Lesion

Xenograft Models of Multiple Myeloma Reveal That PU.1 Serves As a Tumor Suppressor for Multiple Myeloma

A Small Molecule, Shikonin, Dually Functions As a Proteasome Inhibitor and a Necroptosis Inducer In Multiple Myeloma Cells

IDH1 and IDH2 Mutations Confer An Adverse Effect In Patients With Acute Myeloid Leukemia Lacking The NPM1 Mutation

Accumulation Of Gene Alterations Of TP53 , Crebbp and IKZF1 Is a Prognostic Factor In Adult Acute Lymphoblastic Leukemia

Lactate Is a Crucial Energy Source For Multiple Myeloma (MM) Cells In Bone Marrow Microenvironment

Hypoxia Reduces CD138 Expression and Induces Immature Phenotype in Myeloma Cells

IDH2 Mutations Have An Unfavorable Impact in Elderly Patients with Acute Myeloid Leukemia

Decreased CD138 Expression in Myeloma Cells: A Potential Indicator of Poor Prognosis and Aberrant Differentiation,

Aerobic Glycolysis: A Possible Target for Treating Multiple Myeloma (MM) with High Serum LDH Levels

Characteristics of Chronic-Phase CML Patients Having Durable Cytogenetic Response to Low-Dose Imatinib

A JAK2-V617F Activating Mutation in Addition to C-KIT and FLT3 Mutations Is Associated with Clinical Outcome in Patients with t(8;21)(q22;q22;) Acute Myeloid Leukemia.

Clarithromicin Induces Autophagy in Myeloma Cells.

Identification of Hepatic Progenitors Having No Hematopoietic Potential in Murine Bone Marrow.

Kigamicin Induces Necrosis to Human Myeloma Cells by Disruption of Cell Cycle Regulation.

Familial Acute Myeloblastic Leukemia with a Dominant Negative Mutation in the CEBPA Gene.

Hepatogenic Potential of Stem Cells and Lymphoid Precursors.

Appearance of Stress-Inducible Membrane Proteins ULBP on Blood Cells of Patients with PNH, Aplastic Anemia, and MDS: Possible Implication of ULBP in Immune-Mediated Marrow Injury.

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American Society of Hematology

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American Society of Hematology

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