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Journal Articles

Off-Target HLA Cross-Reactivity By (Third Party) Virus-Specific T Cells Is Surprisingly Affected By HLA Restriction and HLA Background but Not By Virus Specificity

Wesley Huisman, MSc, Didier A.T. Leboux, Lieve E. van der Maarel, Lois Hageman, Derk Amsen, PhD, Fred Falkenburg, MD PhD, Inge Jedema, PhD

Blood (2019) 134 (Supplement_1): 4440.

https://doi.org/10.1182/blood-2019-124785

Published: 2019

Journal Articles

The First Functional HLA-a*01:01-Restricted EBV-LMP2-Specific T-Cell Receptors for TCR Gene Therapy of Patients with EBV-Associated Type II/III Malignancies

Wesley Huisman, MSc, Ilse Gille, Lieve E. van der Maarel, Lois Hageman, Rob C.M. de Jong, PhD, Derk Amsen, PhD, Fred Falkenburg, MD PhD, Inge Jedema, PhD

Blood (2019) 134 (Supplement_1): 4448.

https://doi.org/10.1182/blood-2019-123736

Published: 2019

Journal Articles

Whole Transcriptome RNA Sequencing As a Comprehensive Diagnostic Tool for Acute Myeloid Leukemia

Blood (2018) 132 (Supplement 1): 2762.

https://doi.org/10.1182/blood-2018-99-111115

Published: 2018

Journal Articles

Prophylactic Infusion of Multi-Antigen Specific T-Cell Products to Prevent Complications after T Cell Depleted Allogeneic Stem Cell Transplantation — a Phase I/II Study

Marthe C.J. Roex, MD, Peter van Balen, MD, Lothar Germeroth, PhD, Lois Hageman, Esther van Egmond, Sabrina A.J. Veld, Conny Hoogstraten, Ellis van Liempt, PhD, Jaap J. Zwaginga, MD PhD, Liesbeth C. de Wreede, PhD, Hermann Einsele, MD PhD, Hendrik Veelken, MD PhD, Constantijn J.M. Halkes, MD, Inge Jedema, PhD, J.H. Frederik Falkenburg, MD PhD

Blood (2018) 132 (Supplement 1): 119.

https://doi.org/10.1182/blood-2018-99-111749

Published: 2018

Journal Articles

Patient Bone Marrow Chimerism at Time of Donor Lymphocyte Infusion Predicts Development of Graft Versus Host Disease

Eva AS Koster, MD, Liesbeth C. de Wreede, PhD, Sylwia Wallet-Malicka, Lisette Bogers, Peter van Balen, MD, Waf Marijt, MD, Inge Jedema, PhD, Peter von dem Borne, MD PhD, Hendrik Veelken, MD PhD, J.H. Frederik Falkenburg, MD PhD, Constantijn J.M. Halkes, MD

Blood (2018) 132 (Supplement 1): 2132.

https://doi.org/10.1182/blood-2018-99-113839

Published: 2018

Journal Articles

Isolation and Validation of the First Functional HLA-a*01:01 Restricted EBV-LMP2 Specific T Cells for Treatment of EBV Associated Type II/III Lymphomas

Wesley Huisman, MSc, Lieve E. van der Maarel, Lois Hageman, Rob C.M. de Jong, Derk Amsen, PhD, J.H. Frederik Falkenburg, MD PhD, Inge Jedema, PhD

Blood (2018) 132 (Supplement 1): 1578.

https://doi.org/10.1182/blood-2018-99-116127

Published: 2018

Journal Articles

The Scope of Allo-HLA Cross-Reactivity By (Third Party) Virus Specific T Cells Is Surprisingly Affected By HLA Restriction Rather Than Virus Specificity

Wesley Huisman, MSc, Didier A.T. Leboux, Lieve E. van der Maarel, Lois Hageman, Derk Amsen, PhD, J.H. Frederik Falkenburg, MD PhD, Inge Jedema, PhD

Blood (2018) 132 (Supplement 1): 2048.

https://doi.org/10.1182/blood-2018-99-116028

Published: 2018

Journal Articles

Mutated NPM1 As Target for Immunotherapy of Acute Myeloid Leukemia

Dyantha I. Van Der Lee, BSc., Helena M. Bijen, MSc, Renate S. Hagedoorn, ing., Willy M. Honders, ing., Michel G.D. Kester, ing., Dirk M. van der Steen, ing., Arnoud H. de Ru, ing., Inge Jedema, PhD, Hendrik Veelken, MD PhD, Mirjam H.M. Heemskerk, PhD, Peter A. van Veelen, PhD, J.H. Frederik Falkenburg, MD PhD, Marieke Griffioen, PhD

Blood (2017) 130 (Supplement 1): 168.

https://doi.org/10.1182/blood.V130.Suppl_1.168.168

Published: 2017

Journal Articles

The Allo-HLA-DP Restricted T Cell Repertoire Contains a Variety of Tissue-Restricted Specificities with Therapeutic Value

Aicha Laghmouchi, Conny Hoogstraten, Peter Van Balen, MD, Rick van de Water, Marian van de Meent, J.H. Frederik Falkenburg, Prof, MD PhD, Inge Jedema, PhD

Blood (2016) 128 (22): 3356.

https://doi.org/10.1182/blood.V128.22.3356.3356

Published: 2016

Journal Articles

Whole Transcriptome Sequencing (RNAseq) As a Comprehensive, Cost-Efficient Diagnostic Tool for Acute Myeloid Leukemia

Marieke Griffioen, PhD, Wibowo Arindrarto, MSc, Daniel Borràs, MSc, Saskia A.M.E. van Diessen, BSc, Edith D. van der Meijden, M. Willy Honders, Mariam Alloul, PhD, Inge Jedema, PhD, Wilma G.M. Kroes, PhD, Peter J.M. Valk, PhD, Bart Janssen, PhD, Cornelis A.M. van Bergen, PhD, Szymon M. Kiełbasa, PhD, Jeroen F.J. Laros, PhD, Peter A.C. 't Hoen, PhD, Hendrik Veelken, MD PhD

Blood (2016) 128 (22): 1701.

https://doi.org/10.1182/blood.V128.22.1701.1701

Published: 2016

Journal Articles

Prevention of Viral Infections after T Cell Depleted Allogeneic Stem Cell Transplantation By Infusion of Multi-Antigen Specific T Cell Products

Marthe C.J. Roex, MD, Peter Van Balen, MD, Lois Hageman, Esther Van Egmond, Sabrina A.J. Veld, Conny Hoogstraten, Ellis van Liempt, PhD, Lothar Germeroth, PhD, Hermann Einsele, MD, Constantijn J.M. Halkes, MD PhD, Inge Jedema, PhD, J.H. Frederik Falkenburg, MD PhD

Blood (2016) 128 (22): 1228.

https://doi.org/10.1182/blood.V128.22.1228.1228

Published: 2016

Journal Articles

A Polyclonal Population of Piga Mutant CD52 and GPI Anchor Negative T Cells Can Give Early Immune Protection after Alemtuzumab-Based T Cell Depleted Allogeneic Stem Cell Transplantation

Floris C. Loeff, J.H. Frederik Falkenburg, MD PhD, Lois Hageman, Sabrina A.J. Veld, Marian van de Meent, Constantijn J.M. Halkes, MD PhD, Inge Jedema, PhD

Blood (2015) 126 (23): 3134.

https://doi.org/10.1182/blood.V126.23.3134.3134

Published: 2015

Journal Articles

Loss of Pigh Expression Frequently Results in a GPI-Negative Subclone Lacking CD52 Membrane Expression, Conferring Alemtuzumab Resistance to B Cell Acute Lymphoblastic Leukemia

Floris C. Loeff, Kevin Rijs, Willem H. Zoutman, Esther H.M. Egmond, Maarten H. Vermeer, MD PhD, J.H. Frederik Falkenburg, MD PhD, Constantijn J.M. Halkes, MD PhD, Inge Jedema, PhD

Blood (2015) 126 (23): 1435.

https://doi.org/10.1182/blood.V126.23.1435.1435

Published: 2015

Journal Articles

Tumor Associated Antigen Reactive Donor T Cells As Elementary Components of Streptamer Isolated Multi-Antigen Specific T Cells

Marthe C.J. Roex, MD, Ellis van Liempt, PhD, Lois Hageman, Lothar Germeroth, PhD, Constantijn J.M. Halkes, MD PhD, J.H. Frederik Falkenburg, MD PhD, Inge Jedema, PhD

Blood (2014) 124 (21): 313.

https://doi.org/10.1182/blood.V124.21.313.313

Published: 2014

Journal Articles

Effectivity Of Complement-Dependent Cytotoxicity Induced By Therapeutic Antibodies In Acute Lymphoblastic Leukemia Is Dictated By Antigen Expression Levels and Curtailed By Membrane-Bound Complement Regulatory Proteins

Floris C Loeff, MSc, Esther H.M. van Egmond, Judith Olde Wolbers, J.H. Frederik Falkenburg, MD, PhD, Constantijn J.M. Halkes, MD, PhD, Inge Jedema, PhD

Blood (2013) 122 (21): 3909.

https://doi.org/10.1182/blood.V122.21.3909.3909

Published: 2013

Journal Articles

Graft Versus Leukemia Separates From Graft Versus Host Disease By Magnitude and Avidity Of The Allo-Reactive T Cell Response After Allogeneic Stem Cell Transplantation and Donor Lymphocyte Infusion

Cornelis A.M. van Bergen, Simone A.P. Van Luxemburg-Heijs, Matthijs Eefting, MD, Maria W. Honders, Inge Jedema, PhD, Constantijn J.M. Halkes, MD, PhD, Marieke Griffioen, PhD, J.H. Frederik Falkenburg, MD, PhD

Blood (2013) 122 (21): 2014.

https://doi.org/10.1182/blood.V122.21.2014.2014

Published: 2013

Journal Articles

Immune Surveillance By Autoreactive Helper But Not Cytolytic T Cells Is a Common Phenomenon In Patients With Acute Myeloid Leukemia

Tin Sing Lam, Marian van de Meent, J.H. Frederik Falkenburg, MD, PhD, Inge Jedema, PhD

Blood (2013) 122 (21): 1044.

https://doi.org/10.1182/blood.V122.21.1044.1044

Published: 2013

Journal Articles

Collateral Damage of Non-Hematopoietic Tissue by Hematopoiesis-Specific T Cells Results in GvHD During An Ongoing Profound Gvl Reaction,

Boris van der Zouwen, MD, Alwine Kruisselbrink, J.H. Frederik Falkenburg, Inge Jedema, PhD

Blood (2011) 118 (21): 4031.

https://doi.org/10.1182/blood.V118.21.4031.4031

Published: 2011

Journal Articles

Low Incidence of Post-Transplant EBV-Related Disease After Alemtuzumab-Mediated T Cell Depletion Is Explained by the Differential Susceptibility to Alemtuzumab of B Cells and Protective CD8 and CD4 T Cells

Constantijn J.M. Halkes, MD, PhD, Inge Jedema, PhD, Judith Olde Wolbers, Esther M van Egmond, Peter A. Von Dem Borne, MD, PhD, Erik W.A.F. Marijt, MD, PhD, J.H.Frederik Falkenburg, MD, PhD

Blood (2010) 116 (21): 2330.

https://doi.org/10.1182/blood.V116.21.2330.2330

Published: 2010

Journal Articles

Multi-Dimensional Resistance Phenotype Allows Subpopulation of Quiescent Chronic Myeloid Leukemia Stem Cells to Universally Escape From Therapeutic Attack

Inge Jedema, PhD, Linda van Dreunen, Renate S. Hagedoorn, J.H. Frederik Falkenburg, MD, PhD

Blood (2010) 116 (21): 203.

https://doi.org/10.1182/blood.V116.21.203.203

Published: 2010

NARROW

Off-Target HLA Cross-Reactivity By (Third Party) Virus-Specific T Cells Is Surprisingly Affected By HLA Restriction and HLA Background but Not By Virus Specificity

The First Functional HLA-a*01:01-Restricted EBV-LMP2-Specific T-Cell Receptors for TCR Gene Therapy of Patients with EBV-Associated Type II/III Malignancies

Whole Transcriptome RNA Sequencing As a Comprehensive Diagnostic Tool for Acute Myeloid Leukemia

Prophylactic Infusion of Multi-Antigen Specific T-Cell Products to Prevent Complications after T Cell Depleted Allogeneic Stem Cell Transplantation — a Phase I/II Study

Patient Bone Marrow Chimerism at Time of Donor Lymphocyte Infusion Predicts Development of Graft Versus Host Disease

Isolation and Validation of the First Functional HLA-a*01:01 Restricted EBV-LMP2 Specific T Cells for Treatment of EBV Associated Type II/III Lymphomas

The Scope of Allo-HLA Cross-Reactivity By (Third Party) Virus Specific T Cells Is Surprisingly Affected By HLA Restriction Rather Than Virus Specificity

Mutated NPM1 As Target for Immunotherapy of Acute Myeloid Leukemia

The Allo-HLA-DP Restricted T Cell Repertoire Contains a Variety of Tissue-Restricted Specificities with Therapeutic Value

Whole Transcriptome Sequencing (RNAseq) As a Comprehensive, Cost-Efficient Diagnostic Tool for Acute Myeloid Leukemia

Prevention of Viral Infections after T Cell Depleted Allogeneic Stem Cell Transplantation By Infusion of Multi-Antigen Specific T Cell Products

A Polyclonal Population of Piga Mutant CD52 and GPI Anchor Negative T Cells Can Give Early Immune Protection after Alemtuzumab-Based T Cell Depleted Allogeneic Stem Cell Transplantation

Loss of Pigh Expression Frequently Results in a GPI-Negative Subclone Lacking CD52 Membrane Expression, Conferring Alemtuzumab Resistance to B Cell Acute Lymphoblastic Leukemia

Tumor Associated Antigen Reactive Donor T Cells As Elementary Components of Streptamer Isolated Multi-Antigen Specific T Cells

Effectivity Of Complement-Dependent Cytotoxicity Induced By Therapeutic Antibodies In Acute Lymphoblastic Leukemia Is Dictated By Antigen Expression Levels and Curtailed By Membrane-Bound Complement Regulatory Proteins

Graft Versus Leukemia Separates From Graft Versus Host Disease By Magnitude and Avidity Of The Allo-Reactive T Cell Response After Allogeneic Stem Cell Transplantation and Donor Lymphocyte Infusion

Immune Surveillance By Autoreactive Helper But Not Cytolytic T Cells Is a Common Phenomenon In Patients With Acute Myeloid Leukemia

Collateral Damage of Non-Hematopoietic Tissue by Hematopoiesis-Specific T Cells Results in GvHD During An Ongoing Profound Gvl Reaction,

Low Incidence of Post-Transplant EBV-Related Disease After Alemtuzumab-Mediated T Cell Depletion Is Explained by the Differential Susceptibility to Alemtuzumab of B Cells and Protective CD8 and CD4 T Cells

Multi-Dimensional Resistance Phenotype Allows Subpopulation of Quiescent Chronic Myeloid Leukemia Stem Cells to Universally Escape From Therapeutic Attack

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American Society of Hematology

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American Society of Hematology

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