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Isere Kuiatse, PhD
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Journal Articles

The Anti-B-Cell Maturation Antigen (BCMA) Antibody-α-Amanitin Conjugate Hdp-101 Induces Immunogenic Cell Death and Immunologic Memory in Models of Multiple Myeloma

Free
Ram Kumar Singh, PhD, Richard J. Jones, PhD, Fazal M. Shirazi, PhD, Jianxuan M. Zou, PhD, Hua Wang, PhD, Hans C. Lee, MD, Elisabet E. Manasanch, MD, Isere Kuiatse, PhD, Andreas Pahl, PhD, Robert Z. Orlowski, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 9–10.
https://doi.org/10.1182/blood-2020-141615
Published: 2020
Journal Articles

Activating KRAS , NRAS , and BRAF Mutants Enhance Proteasome Capacity and Reduce Endoplasmic Reticulum Stress in Multiple Myeloma, Thereby Promoting Plasma Cell Survival and Proteasome Inhibitor Resistance

Free
Fazal Shirazi, PhD, Richard J. Jones, PhD, Isere Kuiatse, PhD, Zuzana Berkova, PhD, Hua Wang, PhD, Hans C. Lee, MD, Samuel Hong, PhD, Ram Kumar Singh, PhD, Lawrence Robert Dick, PhD, Nibedita Chattopadhyay, PhD, Robert Z. Orlowski, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 406.
https://doi.org/10.1182/blood-2018-99-117577
Published: 2018
Journal Articles

HDP101, a Novel B-Cell Maturation Antigen (BCMA)-Targeted Antibody Conjugated to α-Amanitin, Is Active Against Myeloma with Preferential Efficacy Against Pre-Clinical Models of Deletion 17p

Free
Ram Kumar Singh, PhD, Richard J. Jones, PhD, Samuel Hong, PhD, Fazal Shirazi, PhD, Hua Wang, PhD, Isere Kuiatse, PhD, Andreas Pahl, Robert Z. Orlowski, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 593.
https://doi.org/10.1182/blood-2018-99-118412
Published: 2018
Journal Articles

Protein Homeostatic Modulators, a Novel Class of Cereblon-Targeting Small Molecules As Potential Clinical Candidates in Multiple Myeloma

Free
Jianxuan Zou, PhD, Richard J. Jones, PhD, Janet E. Mertz, PhD, Hua Wang, PhD, Isere Kuiatse, PhD, Bob Sullivan, PhD, Leah Fung, PhD, Normand Richard, PhD, Paul Erdman, PhD, Eduardo Torres, PhD, Aparajita Hoskote Chourasia, PhD, Kyle WH Chan, PhD, Frank Mercurio, PhD, David I Stirling, PhD, Robert Z. Orlowski, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4418.
https://doi.org/10.1182/blood.V130.Suppl_1.4418.4418
Published: 2017
Journal Articles

The Anti-Tumor Effect of the Ubiquitin-Activating Enzyme (UAE) Inhibitor TAK-243 on Pre-Clinical Models of Multiple Myeloma

Free
Junling Zhuang, MD PhD, Hans Lee, MD, Isere Kuiatse, PhD, Hua Wang, PhD, Fazal Shirazi, PhD, Allison Berger, PhD, Marc Hyer, PhD, Nibedita Chattopadhyay, PhD, Sakeena Syed, Judy Qiuju Shi, Jie Yu, M.S., Vaishali Shinde, Anna Kreshock, Stephen Tirrell, PhD, Saurabh Menon, PhD, Richard Julian Jones, PhD, Robert Z. Orlowski, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3296.
https://doi.org/10.1182/blood.V128.22.3296.3296
Published: 2016
Journal Articles

RNA Polymerase I Inhibition with CX-5461 As a Novel Strategy to Target MYC in Multiple Myeloma

Free
Hans Lee, MD, Hua Wang, PhD, Heather Lin, M.S., Veera Baladandayuthapani, PhD, Jin He, Richard Julian Jones, PhD, Isere Kuiatse, PhD, Dongmin Gu, MD, PhD, Zhiqiang Wang, PhD, Sean O'Brien, PhD, Jonathan J Keats, PhD, Jing Yang, PhD, Richard Eric Davis, MD, Robert Z. Orlowski, PhD, MD
Journal: Blood
Blood (2015) 126 (23): 3010.
https://doi.org/10.1182/blood.V126.23.3010.3010
Published: 2015
Journal Articles

Studies of the Proteasome Inhibitor Sensitivity Modulator Tight Junction Protein 1 Highlight a Role for Signaling through the Epidermal Growth Factor Receptor in Determining Proteasome Capacity

Free
Xing-Ding Zhang, PhD, Veerabhadran Baladandayuthapani, PhD, Heather Yan Lin, PhD, George Mulligan, PhD, Bin Li, PhD, Dixie-Lee Esseltine, MD, Lin Qi, PhD, Jian-Liang Xu, PhD, Walter Hunziker, PhD, Bart Barlogie, MD, PhD, Saad Z. Usmani, MD, Qing Zhang, PhD, John Crowley, PhD, Antje Hoering, PhD, Bing-Zong Li, MD, PhD, Huihan Wang, MD, PhD, Jiexin Zhang, M.S., Isere Kuiatse, PhD, Jin-Le Tang, PhD, Jin He, Jing Yang, PhD, Richard Eric Davis, MD, Wencai Ma, PhD, Zhiqiang Wang, PhD, Lin Yang, MD, PhD, Robert Z. Orlowski, PhD MD
Journal: Blood
Blood (2014) 124 (21): 3414.
https://doi.org/10.1182/blood.V124.21.3414.3414
Published: 2014
Journal Articles

Mucin 20 (MUC20) Modulates Proteasome Assembly Chaperones through the c-MET Pathway and Is a Biomarker of Proteasome Inhibitor Sensitivity in Myeloma

Free
Huihan Wang, MD, PhD, Veerabhadran Baladandayuthapani, PhD, Heather Yan Lin, PhD, Xiaobin Wang, MD, Bingzong Li, MD, PhD, Xing-Ding Zhang, PhD, Isere Kuiatse, PhD, Hua Wang, PhD, Dongmin Gu, MD, PhD, Liye Zhong, PhD, Wencai Ma, PhD, Richard E. Davis, MD, Robert Z. Orlowski, MD, PhD
Journal: Blood
Blood (2014) 124 (21): 274.
https://doi.org/10.1182/blood.V124.21.274.274
Published: 2014