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Journal Articles

RNA:m 5 c/Methyltransferases Mediate Chromatin Organization and 5-Azacytidine Response/Resistance in Leukemia

Jason Cheng, MD PhD, Li Chen, PhD MD, Yuan Li, MD, Ming Yue, PhD, Adam Cloe, MD, PhD, Jamile M. Shammo, MD FASCP, FACP, Richard A. Larson, MD, Chuan He, PhD, Michelle M. Le Beau, PhD, James W. Vardiman, MD

Blood (2017) 130 (Supplement 1): 2471.

https://doi.org/10.1182/blood.V130.Suppl_1.2471.2471

Published: 2017

Journal Articles

Bromodomain and Extra-Terminal Motif Proteins (BETs) Mediate 5-Azacitidine Resistance in Myeloid Leukemia through Recruitment of an Active RNA Polymerase II Complex

Li Chen, MD PhD, Yuan Li, MD, Ming Yue, PhD, Adam Cloe, MD PhD, Michelle M. Le Beau, PhD, Chuan He, PhD, Richard A. Larson, MD, James W. Vardiman, MD, Jason X. Cheng, MD PhD

Blood (2016) 128 (22): 746.

https://doi.org/10.1182/blood.V128.22.746.746

Published: 2016

Journal Articles

Epigenetic Modifying Drugs Inhibit MDS/AML Cell Growth through Selective Disruption of the Interactions Between Lineage-Determining Transcription Factors and DNA/Histone Modifiers

Yuan Li, MD, Ming Yue, PhD, John Anastasi, MD, Jeffery Q Shen, PhD, Yali Dou, PhD, Richard A. Larson, MD, James W. Vardiman, MD, Jason X. Cheng, MDPhD

Blood (2015) 126 (23): 3853.

https://doi.org/10.1182/blood.V126.23.3853.3853

Published: 2015

Journal Articles

Brca1 Deficiency Causes Bone Marrow Failure and Spontaneous Hematologic Malignancies in Mice

Aparna Vasanthakumar, BSc, MSc, PhD, Stephen Arnovitz, Rafael Marquez, Janet Lepore, George Rafidi, Elizabeth M. Davis, BS, Anase Asom, Madison Weatherly, Barbara Neistadt, Robert Duszynski, James W. Vardiman, MD, Michelle M. Le Beau, PhD, Lucy A. Godley, MD PhD, Jane E. Churpek, MD

Blood (2015) 126 (23): 295.

https://doi.org/10.1182/blood.V126.23.295.295

Published: 2015

Journal Articles

Disease-Associated Chromatin Conformation and Therapeutic Implications In Leukemia

Jason X Cheng, MD, PhD, John Anastasi, MD, James W. Vardiman, MD

Blood (2013) 122 (21): 4892.

https://doi.org/10.1182/blood.V122.21.4892.4892

Published: 2013

Journal Articles

PLZF Staining Identifies Peripheral T-Cell Lymphomas Derived From Non-Conventional T-Cells With Limited α-Chain Diversity

Stephanie McGregor, MD, PhD, Anant Shah, Gordana Raca, Kamran Mirza, MD PHD, John Anastasi, MD, James W. Vardiman, MD, Elizabeth Hyjek, MD, PhD, Sandeep Gurbuxani, MBBS, PhD

Blood (2013) 122 (21): 4300.

https://doi.org/10.1182/blood.V122.21.4300.4300

Published: 2013

Journal Articles

Clinicopathologic Characterization of Acute Myeloid Leukemia and Myelodysplastic Syndrome with Inv(3)(q21q26.2)/t(3;3)(q21;q26.2) Reveals That Complex Karyotype but Not Blast Percentage Is Associated with Poor Survival; A Bone Marrow Pathology Group Study

Heesun J. Rogers, MD, PhD, James W. Vardiman, MD, John Anastasi, MD, Gordana Raca, MD, PhD, Natasha M Savage, MD, Athena M Cherry, Ph.D., Daniel Arber, MD, Erika Moore, MD, Jennifer JD Morrissette, PhD, Adam Bagg, MD, Yen-Chun Liu, MD, PHD, Susan Mathew, PhD, Attilio Orazi, MD, Pei Lin, MD, Sa A. Wang, MD, Carlos E. Bueso-Ramos, MD, PhD, Kathryn Foucar, MD, Robert P Hasserjian, MD, Eric D. Hsi, MD

Blood (2012) 120 (21): 3847.

https://doi.org/10.1182/blood.V120.21.3847.3847

Published: 2012

Journal Articles

A Novel Epigenetic Mechanism in the Pathogenesis of Myelodysplastic Syndrome (MDS)

Jason X Cheng, MD, PhD, John Anastasi, MD, Jeffery Q Shen, PhD, Kenneth Q Watanabe, Edward Grimley, Erica Kleinbrink, Randal Knibbs, PhD, James W. Vardiman, MD

Blood (2011) 118 (21): 2783.

https://doi.org/10.1182/blood.V118.21.2783.2783

Published: 2011

Journal Articles

Pomalidomide Therapy in Anemic Patients with Myelofibrosis: Results from a Phase-2 Randomized Multicenter Study

Ayalew Tefferi, MD, Srdan Verstovsek, Giani Barosi, Francesco Passamonti, MD, Gail J. Roboz, MD, Heinz Gisslinger, Ronald Paquette, MD, Francisco Cervantes, MD, Candido E. Rivera, MD, H. Joachim Deeg, Juergen Thiele, Hans Michael Kvasnicka, James W. Vardiman, MD, B. Nebiyou Bekele, PhD, Ruben A. Mesa, MD, FACP, Robert P Gale, Hagop M Kantarjian

Blood (2008) 112 (11): 663.

https://doi.org/10.1182/blood.V112.11.663.663

Published: 2008

Journal Articles

Daunorubicin Dose Intensification during Treatment of Adult Acute Lymphoblastic Leukemia (ALL): Final Results from Cancer and Leukemia Group B Study 19802.

Wendy Stock, MD, Jeffrey Johnson, MS, Daohai Yu, PhD, Diane Bennett, BSN, Dorie Sher, BS, Richard M. Stone, MD, Jonathan E. Kolitz, MD, Bayard L. Powell, MD, Meir Wetzler, MD, James W. Vardiman, MD, Clara D. Bloomfield, MD, Richard A. Larson, MD

Blood (2005) 106 (11): 1833.

https://doi.org/10.1182/blood.V106.11.1833.1833

Published: 2005

Journal Articles

Sequential Phase II Studies of Flavopiridol by 72-Hour Continuous Infusion and 1-Hour Intravenous Bolus for the Treatment of Relapsed B-Cell Chronic Lymphocytic Leukemia: Results from CALGB Study 19805.

John C. Byrd, MD, Bercedis L. Peterson, PhD, Janice L. Gabrilove, MD, Olatoyosi M. Odenike, MD, Michael R. Grever, MD, Kanti R. Rai, MD, James W. Vardiman, MD, Richard A. Larson, MD, Cancer and Leukemia Group B

Blood (2004) 104 (11): 3485.

https://doi.org/10.1182/blood.V104.11.3485.3485

Published: 2004

NARROW

RNA:m 5 c/Methyltransferases Mediate Chromatin Organization and 5-Azacytidine Response/Resistance in Leukemia

Bromodomain and Extra-Terminal Motif Proteins (BETs) Mediate 5-Azacitidine Resistance in Myeloid Leukemia through Recruitment of an Active RNA Polymerase II Complex

Epigenetic Modifying Drugs Inhibit MDS/AML Cell Growth through Selective Disruption of the Interactions Between Lineage-Determining Transcription Factors and DNA/Histone Modifiers

Brca1 Deficiency Causes Bone Marrow Failure and Spontaneous Hematologic Malignancies in Mice

Disease-Associated Chromatin Conformation and Therapeutic Implications In Leukemia

PLZF Staining Identifies Peripheral T-Cell Lymphomas Derived From Non-Conventional T-Cells With Limited α-Chain Diversity

Clinicopathologic Characterization of Acute Myeloid Leukemia and Myelodysplastic Syndrome with Inv(3)(q21q26.2)/t(3;3)(q21;q26.2) Reveals That Complex Karyotype but Not Blast Percentage Is Associated with Poor Survival; A Bone Marrow Pathology Group Study

A Novel Epigenetic Mechanism in the Pathogenesis of Myelodysplastic Syndrome (MDS)

Pomalidomide Therapy in Anemic Patients with Myelofibrosis: Results from a Phase-2 Randomized Multicenter Study

Daunorubicin Dose Intensification during Treatment of Adult Acute Lymphoblastic Leukemia (ALL): Final Results from Cancer and Leukemia Group B Study 19802.

Sequential Phase II Studies of Flavopiridol by 72-Hour Continuous Infusion and 1-Hour Intravenous Bolus for the Treatment of Relapsed B-Cell Chronic Lymphocytic Leukemia: Results from CALGB Study 19805.

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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