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Jeff Wrana, PhD
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Journal Articles

Ibrutinib Sensitizes AML Cells to ROS Inducers Via a BTK-Independent Mechanism

Lianne E Rotin, BHSc, Marcela Gronda, MSc, Neil Maclean, BSc, Feng-Hsu Lin, PhD, Jeff Wrana, PhD, Alessandro Datti, PhD, Dwayne L Barber, PhD, Michael F Moran, PhD, Mark D Minden, MDPhD, Malik Slassi, PhD, Aaron D Schimmer, MDPhD
Journal: Blood
Blood (2014) 124 (21): 2226.
https://doi.org/10.1182/blood.V124.21.2226.2226
Published: 2014
Journal Articles

Inhibition of Fatty Acid Oxidation with Avocatin B Selectively Targets AML Cells and Leukemia Stem Cells

Eric A Lee, Leonard Angka, Sarah-Grace Rota, Thomas Hanlon, Rose Hurren, Xiao Ming Wang, Marcela Gronda, MSc, Dannie Bernard, Mark D. Minden, MD PhD, Andrew Mitchell, Andrea Edginton, PhD, Shrivani Sriskanthadevan, PhD, Alessandro Datti, PhD, Jeff Wrana, PhD, Jamie W Joseph, PhD, Joe Quadrilatero, PhD, Aaron D. Schimmer, MD PhD, Paul A Spagnuolo, PhD
Journal: Blood
Blood (2014) 124 (21): 268.
https://doi.org/10.1182/blood.V124.21.268.268
Published: 2014
Journal Articles

A Small Molecule Inhibitor of D-Cyclin Transactivation Displays Preclinical Efficacy in Myeloma and Leukemia.

Xinliang Mao, MD, PhD, Tabitha E Wood, PhD, Rose Hurren, Jiefei Tong, PhD, Xiaoming Wang, Paul A. Spagnuolo, PhD, Neil MacLean, Michael F. Moran, PhD, Alessandro Datti, Jeff Wrana, PhD, Robert A. Batey, PhD, Aaron D. Schimmer, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 2036.
https://doi.org/10.1182/blood.V114.22.2036.2036
Published: 2009
Journal Articles

A Novel Chromene-Based Pan-PI3 Kinase Inhibitor Displays Preclinical Activity in Leukemia and Myeloma.

Xinliang Mao, MD, PhD, Tabitha W. Wood, PhD, Xiaoming Wang, PhD, Johnathan St-Germain, BSc, Michael F. Moran, PhD, Alessandro Datti, PhD, Jeff Wrana, PhD, Robert A. Batey, PhD, Aaron D. Schimmer, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 1605.
https://doi.org/10.1182/blood.V112.11.1605.1605
Published: 2008