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Journal Articles

Targeting Oncoproteins with a Positive Selection Assay for Protein Degraders

Sagar Koduri, MD PhD, Adam C. Wang, B.S., Mette Ishoey, PhD, Joshiawa Paulk, Xiaoxi Liu, PhD, Isaac Harris, PhD, Jennifer Endress, B.S., Benjamin L. Lampson, MD PhD, Christopher J. Ott, PhD, James Bradner, MD, Jeffrey A. Medin, PhD, Sara J Buhrlage, PhD, William Kaelin, MD

Blood (2020) 136 (Supplement 1): 13–14.

https://doi.org/10.1182/blood-2020-141558

Published: 2020

Journal Articles

CAR-Modified Th1/Tc1-Polarized T-Rapa Cells Dissociate Inflammatory Cytokine Secretion from Anti-Tumor Cytotoxicity

Robyn A. A. Oldham, BSc, Tania Felizardo, PhD, Nathaniel Zhu, Daniel H. Fowler, MD, Jeffrey A. Medin, PhD

Blood (2018) 132 (Supplement 1): 2046.

https://doi.org/10.1182/blood-2018-99-113642

Published: 2018

Journal Articles

BMT Doubles The Lifespan Of A Mouse Model Of Farber Disease and Corrects Hematopoietic Defects

Shaalee Dworski, MSc, Alexandra Berger, PhD, Caren Furlonger, Christopher J. Paige, PhD, Jeffrey A. Medin, PhD

Blood (2013) 122 (21): 1997.

https://doi.org/10.1182/blood.V122.21.1997.1997

Published: 2013

Journal Articles

Systemic Ceramide Accumulation Causes Dysregulated Hematopoiesis

Shaalee Dworski, MSc, Alexandra Berger, PhD, Makoto Yoshimitsu, MD PhD, Abdulfatah Alayoubi, MBBS, Bryan Au, MSc, Mathilde Exertier, Jessa Forster, Caren Furlonger, James C Wang, MSc, Toshihiro Takenaka, MD PhD, Christopher J. Paige, PhD, Jeffrey A. Medin, PhD

Blood (2012) 120 (21): 3461.

https://doi.org/10.1182/blood.V120.21.3461.3461

Published: 2012

Journal Articles

Generation and Implementation of a Novel Murine Xenograft Model for Evaluating Human Hematopoietic Cell-Targeted Gene Therapies for Fabry Disease.

Natalia A. Pacienza, PhD, Nobuo Mizue, PhD, Makoto Yoshimitsu, MD, Matthew Scaife, BSc, Ronan Foley, MD, FRCPC, Jeffrey A. Medin, PhD

Blood (2009) 114 (22): 3576.

https://doi.org/10.1182/blood.V114.22.3576.3576

Published: 2009

Journal Articles

PD-L1 Immuno-Gene Therapy Under Cell Fate Control: Persistence of Cellular Delivery Vehicle and Transgene Expression.

Shoba Amarnath, PhD, James CM Wang, Paul R. Massey, James L. Riley, Bruce Levine, PhD, Carl H. June, MD, Jeffrey A. Medin, PhD, Daniel Fowler, MD

Blood (2009) 114 (22): 3580.

https://doi.org/10.1182/blood.V114.22.3580.3580

Published: 2009

Journal Articles

Use of MGMT Resistance to Enrich for Transduced Hematopoietic Cells in Gene Therapy for Fabry Disease.

Natalia A. Pacienza, PhD, Nobuo Mizue, PhD, Matthew Scaife, BSc, Ronan Foley, MD, FRCPC, Jeffrey A. Medin, PhD

Blood (2009) 114 (22): 3584.

https://doi.org/10.1182/blood.V114.22.3584.3584

Published: 2009

Journal Articles

Gamma Delta T Cells (GDTCs) to Eliminate Minimal Residual Disease (MRD) in Chronic Myeloid Leukemia (CML) : A Pre-Clinical Model

Gabrielle Melanie Siegers, PhD, Bassim Malas Al-Beirouti, MD, Alister Mark Mathieson, MSc., Tania Cristina Felizardo, PhD, Simone Helke, Jeffrey A. Medin, PhD, Armand Keating, MD

Blood (2008) 112 (11): 574.

https://doi.org/10.1182/blood.V112.11.574.574

Published: 2008

Journal Articles

Development of Improved Lentiviral ‘Suicide’ Gene Therapy for the Management of GvHD and GvL/GvT Responses in Allogeneic BMT.

Anton Neschadim, MSc, Takeya Sato, PhD, Daniel H. Fowler, MD, Arnon Lavie, PhD, Jeffrey A. Medin, PhD

Blood (2006) 108 (11): 3256.

https://doi.org/10.1182/blood.V108.11.3256.3256

Published: 2006

Journal Articles

Overcoming Self-Tolerance: Long-Term Protection Against Specific erbB2-Expressing Prostate Tumors Using Low Doses of Lentivirus-Transduced DCs.

Miriam E. Mossoba, Jagdeep S. Walia, MD, Vanessa I. Rasaiah, Daniel H. Fowler, MD, Jeffrey A. Medin, PhD

Blood (2006) 108 (11): 3696.

https://doi.org/10.1182/blood.V108.11.3696.3696

Published: 2006

Journal Articles

Improved Suicide Gene Therapy: Lentiviral Gene Transfer of Equine Herpes Virus Type 4 Thymidine Kinase into Target Cells.

Takeya Sato, PhD, Anton Neschadim, Vanessa I. Rasaiah, Manfred Konrad, PhD, Daniel H. Fowler, MD, Arnon Lavie, PhD, Jeffrey A. Medin, PhD

Blood (2005) 106 (11): 5251.

https://doi.org/10.1182/blood.V106.11.5251.5251

Published: 2005

Journal Articles

Initiation of a Pre-Clinical Gene Therapy Study in Non-Human Primates Using Lentivectors Targeting Hematopoietic Cells for Correction of Fabry Disease.

Jagdeep S. Walia, MBBS, Makoto Yoshimitsu, MD, Josh D. Silvertown, PhD, Armando Poeppl, Vanessa I. Rasaiah, BSc, Robert E. Donahue, DVM, Robert G. Andrews, MD, J. Andrea McCart, MD, Jeffrey A. Medin, PhD

Blood (2005) 106 (11): 5542.

https://doi.org/10.1182/blood.V106.11.5542.5542

Published: 2005

Journal Articles

A Novel Suicide Gene Therapy Approach for Reduction of GvHD Using Lentiviral Delivery of a Modified Human Thymidylate Monophosphate Kinase.

Takeya Sato, PhD, Anton Neschadim, Vanessa I. Rasaiah, Manfred Konrad, PhD, Daniel H. Fowler, MD, Arnon Lavie, PhD, Jeffrey A. Medin, PhD

Blood (2005) 106 (11): 5252.

https://doi.org/10.1182/blood.V106.11.5252.5252

Published: 2005

Journal Articles

Novel Mechansims for P k (Gb 3 ) Inhibition of HIV Infection.

Nicole Lund, Clifford A. Lingwood, PhD, Jeffrey A. Medin, PhD, Martin L. Olsson, MD, PhD, Cyril Levene, MD, Vered Yahalom, MD, Donald R. Branch, PhD

Blood (2005) 106 (11): 1430.

https://doi.org/10.1182/blood.V106.11.1430.1430

Published: 2005

Journal Articles

Long-Term and Sustained Correction of the α-Galactosidase A Deficiency in Fabry Mice and Patient Cells Receiving Lentivirally Transduced Hematopoietic Stem/Progenitor Cells.

Makoto Yoshimitsu, MD, Christopher Siatskas, PhD, Sheng-Ben Liang, MD, PhD, Vanessa I. Rasaiah, Koji Higuchi, MD, Gary J. Murray, PhD, Toshihiro Takenaka, MD, PhD, Chuwa Tei, MD, PhD, Roscoe O. Brady, MD, Jeffrey A. Medin, PhD

Blood (2005) 106 (11): 1285.

https://doi.org/10.1182/blood.V106.11.1285.1285

Published: 2005

Journal Articles

Functional Engraftment of Retrovirally Transduced and Pre-Selected Hematopoietic Cells into Partially Ablated Recipient Fabry Mice.

Jeffrey A. Medin, PhD, Sheng-Ben Liang, MD, PhD, Armando Poeppl, Makoto Yoshimitsu, MD, Jagdeep S. Walia, MBBS, Jianhui Cai, MD, PhD, Vanessa I. Rasaiah, Daniel H. Fowler, MD

Blood (2005) 106 (11): 3023.

https://doi.org/10.1182/blood.V106.11.3023.3023

Published: 2005

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Targeting Oncoproteins with a Positive Selection Assay for Protein Degraders

CAR-Modified Th1/Tc1-Polarized T-Rapa Cells Dissociate Inflammatory Cytokine Secretion from Anti-Tumor Cytotoxicity

BMT Doubles The Lifespan Of A Mouse Model Of Farber Disease and Corrects Hematopoietic Defects

Systemic Ceramide Accumulation Causes Dysregulated Hematopoiesis

Generation and Implementation of a Novel Murine Xenograft Model for Evaluating Human Hematopoietic Cell-Targeted Gene Therapies for Fabry Disease.

PD-L1 Immuno-Gene Therapy Under Cell Fate Control: Persistence of Cellular Delivery Vehicle and Transgene Expression.

Use of MGMT Resistance to Enrich for Transduced Hematopoietic Cells in Gene Therapy for Fabry Disease.

Gamma Delta T Cells (GDTCs) to Eliminate Minimal Residual Disease (MRD) in Chronic Myeloid Leukemia (CML) : A Pre-Clinical Model

Development of Improved Lentiviral ‘Suicide’ Gene Therapy for the Management of GvHD and GvL/GvT Responses in Allogeneic BMT.

Overcoming Self-Tolerance: Long-Term Protection Against Specific erbB2-Expressing Prostate Tumors Using Low Doses of Lentivirus-Transduced DCs.

Improved Suicide Gene Therapy: Lentiviral Gene Transfer of Equine Herpes Virus Type 4 Thymidine Kinase into Target Cells.

Initiation of a Pre-Clinical Gene Therapy Study in Non-Human Primates Using Lentivectors Targeting Hematopoietic Cells for Correction of Fabry Disease.

A Novel Suicide Gene Therapy Approach for Reduction of GvHD Using Lentiviral Delivery of a Modified Human Thymidylate Monophosphate Kinase.

Novel Mechansims for P k (Gb 3 ) Inhibition of HIV Infection.

Long-Term and Sustained Correction of the α-Galactosidase A Deficiency in Fabry Mice and Patient Cells Receiving Lentivirally Transduced Hematopoietic Stem/Progenitor Cells.

Functional Engraftment of Retrovirally Transduced and Pre-Selected Hematopoietic Cells into Partially Ablated Recipient Fabry Mice.

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