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Jeremy Ryan, SM
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Journal Articles

BH3 Profiling Identifies Bcl-2 Dependency in Multiple Myeloma and Predicts Sensitivity to BH3 Mimetics

Cyrille Touzeau, MD, Jeremy Ryan, SM, Philippe Moreau, MD, Triona Ni Chonghaile, PhD, Steven Le Gouill, Paul G. Richardson, Kenneth C. Anderson, Martine Amiot, PhD, Anthony G. Letai, MD PhD
Journal: Blood
Blood (2014) 124 (21): 417.
https://doi.org/10.1182/blood.V124.21.417.417
Published: 2014
Journal Articles

Low-Dose IL-2 Reduces Mitochondrial Priming and Increases Bcl2 Expression in CD4 Memory Regulatory T Cells

Kazuyuki Murase, MD PhD, Haesook T. Kim, PhD, Masahiro Hirakawa, MD PhD, Tiago Reis Matos, MD, Yutaka Kawano, MD PhD, Jeremy Ryan, SM, Ken-Ichi Matsuoka, MDPhD, John Koreth, MBBS, DPhil, Robert J Soiffer, MD, Anthony G. Letai, MD PhD, Junji Kato, MD PhD, Jerome Ritz, MD
Journal: Blood
Blood (2014) 124 (21): 1414.
https://doi.org/10.1182/blood.V124.21.1414.1414
Published: 2014
Journal Articles

Mitochondrial Apoptotic Priming Is Associated with Clinical Response to the Bcl-2 Antagonist ABT-199 in Chronic Lymphocytic Leukemia

Matthew S. Davids, MD, Jing Deng, PhD, Jeremy Ryan, SM, Stacey M. Fernandes, Jennifer R. Brown, Anthony G. Letai, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1940.
https://doi.org/10.1182/blood.V124.21.1940.1940
Published: 2014
Journal Articles

Type II JAK2 Inhibitor NVP-CHZ868 Is Active in Vivo Against JAK2-Dependent B-Cell Acute Lymphoblastic Leukemias (B-ALLs)

Loretta S. Li, MD, Shuo-Chieh Wu, Nadja Kopp, MA, Joan Montero, PhD, Jeremy Ryan, SM, Bjoern Chapuy, MD PhD, Jordy C. Van der Zwet, Jacob Layer, Oliver Weigert, MD, Amanda L Christie, Alexandra N. Christodoulou, Huiyun Liu, Akinori Yoda, PhD, Francesco Hofmann, PhD, Fabienne Baffert, Eric Vangrevelinghe, Christoph Gaul, PhD, Thomas Radimerski, PhD, Anthony G. Letai, MD PhD, David M. Weinstock, MD
Journal: Blood
Blood (2014) 124 (21): 3713.
https://doi.org/10.1182/blood.V124.21.3713.3713
Published: 2014
Journal Articles

Low-Dose IL-2 Induces Bcl2 Expression and Resistance To Apoptosis In CD4 Regulatory T Cells

Kazuyuki Murase, MD, PhD, Yutaka Kawano, MD, PhD, Jeremy Ryan, SM, Ken-ichi Matsuoka, MD, PhD, Gregory Bascug, BS, Sean McDonough, MS, Robert W Smith, BS, Kristen Cowens, Suzan Lazo-Kallanian, John Daley, PhD, John Koreth, MBBS, DPhil, Robert J. Soiffer, MD, Anthony Letai, MD, PhD, Jerome Ritz, MD
Journal: Blood
Blood (2013) 122 (21): 3475.
https://doi.org/10.1182/blood.V122.21.3475.3475
Published: 2013
Journal Articles

BH3 Profiling Predicts On-Target Cell Death Due To Selective Inhibition Of BCL-2 By ABT-199 In Acute Myelogenous Leukemia

Leah Hogdal, Daniel J. DeAngelo, MD, Ph.D, Richard M. Stone, MD, Verena I. Gaidzik, MD, Donna Bucci, Konstanze Döhner, MD, Guido Marcucci, MD, Jeremy Ryan, SM, Anthony Letai, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 238.
https://doi.org/10.1182/blood.V122.21.238.238
Published: 2013