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Journal Articles

The High Mobility Group A1 Chromatin Regulator Is Required for Pathologic Megakaryocyte Development and Progression to Myelofibrosis in JAK2V617F Murine Models

Alison R. Moliterno, MD, Donna Marie Williams, PhD, Liping Li, MD PhD, Lingling Xian, MD PhD, Li Luo, PhD, Amy S. Duffield, MD PhD, Ophelia Rogers, Jerry L. Spivak, MD, Linda Resar, MD

Blood (2019) 134 (Supplement_1): 472.

https://doi.org/10.1182/blood-2019-131432

Published: 2019

Journal Articles

High Mobility Group A1 Chromatin Regulators: Key Epigenetic Switches and Therapeutic Targets Required for Leukemic Transformation in JAK2 Mutant MPN

Liping Li, MD PhD, Wenyan Lu, PhD, Alison R. Moliterno, MD, Lingling Xian, MD PhD, Joseph Kim, BS, Ophelia Rogers, Jerry L. Spivak, MD, Linda Resar, MD

Blood (2019) 134 (Supplement_1): 1680.

https://doi.org/10.1182/blood-2019-130262

Published: 2019

Journal Articles

Worse Outcomes in Males with MPN Are Associated with Qualitative and Quantitative Differences in Non-Driver Mutational Burden

Theodoros Karantanos, MD PhD, Evan M Braunstein, MD PhD, Shruti Chaturvedi, MBBS, MS, Jerry L. Spivak, MD, Linda Resar, MD, Styliani Karanika, MD, Donna Marie Williams, PhD, Christopher D Gocke, MD, Alison R. Moliterno, MD

Blood (2019) 134 (Supplement_1): 837.

https://doi.org/10.1182/blood-2019-125393

Published: 2019

Journal Articles

Development of Liver-Specific Thrombopoietin Targeted Sirnas: Impact on Platelet Count, Megakaryocyte Mass, and Hematopoietic Progenitors in Normal and MPN Murine Models

Dhruv Desai, MSc, Anna Borodovsky, PhD, Wendell P Davis, DVM DACVP, Rohan Degaonkar, Kristina Yucius, Kellie D'Angelo, MLS(ASCP)CM, Paul Gedman, BS, Donna Marie Williams, PhD, Ophelia Rogers, Zhizhuang Joe Zhao, PhD, Jerry L. Spivak, MD, Alison R. Moliterno, MD

Blood (2018) 132 (Supplement 1): 4329.

https://doi.org/10.1182/blood-2018-99-117142

Published: 2018

Journal Articles

High Mobility Group A1 Chromatin Remodeling Proteins Amplify Inflammatory Networks to Drive Leukemic Transformation in Chronic Myeloproliferative Neoplasia in Humans and JAK2 V617F Transgenic Mouse Models

Linda Resar, MD, Donna Marie Williams, PhD, Lingling Xian, MD PhD, Wenyan Lu, PhD, Briyana Chisholm, BS, Li Luo, PhD, Zhizhuang Joe Zhao, PhD, Ophelia Rogers, Jerry L. Spivak, MD, Alison R. Moliterno, MD

Blood (2018) 132 (Supplement 1): 102.

https://doi.org/10.1182/blood-2018-99-119549

Published: 2018

Journal Articles

Independent Association of Male Sex with Presentation and Clinical Outcomes in Myeloproliferative Neoplasms

Theodoros Karantanos, MDPhD, Shruti Chaturvedi, MBBS,MS, Jerry L. Spivak, MD, Linda Resar, MD, Evan M Braunstein, MDPhD, Styliani Karanika, MD, Donna Marie Williams, PhD, Ophelia Rogers, Alison R. Moliterno, MD

Blood (2018) 132 (Supplement 1): 1768.

https://doi.org/10.1182/blood-2018-99-112683

Published: 2018

Journal Articles

Myeloproliferative Neoplasms in Pediatrics and Young Adults: Genetic Lesions, Diagnostic Features, and Clinical Outcomes

Linda Resar, MD, Donna Marie Williams, PhD, Evan M Braunstein, MDPhD, Jerry L. Spivak, MD, Alison R. Moliterno, MD

Blood (2017) 130 (Supplement 1): 4180.

https://doi.org/10.1182/blood.V130.Suppl_1.4180.4180

Published: 2017

Journal Articles

Mechanism of Escape from LNK Negative Regulation: Constitutively Active JAK2V617F Retains Lysine63-Ubiquitin

Jeffrey Patterson-Fortin, MD PhD, Jerry L. Spivak, MD, Amy S. Duffield, MD PhD, Donna Marie Williams, PhD, Ophelia Rogers, Zhizhuang Joe Zhao, PhD, Alison R. Moliterno, MD

Blood (2017) 130 (Supplement 1): 2931.

https://doi.org/10.1182/blood.V130.Suppl_1.2931.2931

Published: 2017

Journal Articles

High Mobility Group A1 Chromatin Remodeling Proteins: Potential Therapeutic Targets Involved in Polycythemia Vera Transformation to Acute Leukemia in Humans and JAK2 V617F Transgenic Mouse Models

Linda Resar, MD, Donna Marie Williams, PhD, Lingling Xian, MD PhD, Zhizhuang Joe Zhao, PhD, Ophelia Rogers, Jerry L. Spivak, MD, Alison R. Moliterno, MD

Blood (2017) 130 (Supplement 1): 489.

https://doi.org/10.1182/blood.V130.Suppl_1.489.489

Published: 2017

Journal Articles

Germline ERBB2 Variants Associate with Myeloproliferative Neoplasms

Evan M Braunstein, MDPhD, Donna Marie Williams, PhD, Igor Makhlin, MD, Aparna Pallavajjala, Christopher D Gocke, MD, Nara Sobreira, MD, Kala Visvanathan, MD, Linda Resar, MD, Jerry L. Spivak, MD, Alison R. Moliterno, MD

Blood (2017) 130 (Supplement 1): 1663.

https://doi.org/10.1182/blood.V130.Suppl_1.1663.1663

Published: 2017

Journal Articles

Generation, Characterization and Genetic Modification of Human iPSCs Containing Calr , MPL and JAK2 Mutations Found in MPN Patients

Liu Senquan, BS, Donna Marie Williams, PhD, Alison R. Moliterno, MD, Jerry L. Spivak, MD, He Huang, MD PhD, Yongxing Gao, BS, Zhaohui Ye, PhD, Linzhao Cheng, PhD

Blood (2016) 128 (22): 3139.

https://doi.org/10.1182/blood.V128.22.3139.3139

Published: 2016

Journal Articles

Multicenter Analysis of Clinical Characteristics and Long-Term Outcomes of Transjugular Intrahepatic Portosystemic Shunt Procedure for MPN-Associated Portal Hypertension

Christopher R Reilly, MD, Daria V. Babushok, MD PhD, Karlyn Martin, MD, Jerry L. Spivak, MD, Michael Streiff, MD, Brady Stein, MD, Alison R Moliterno, MD, Elizabeth O. Hexner, MD

Blood (2016) 128 (22): 1943.

https://doi.org/10.1182/blood.V128.22.1943.1943

Published: 2016

Journal Articles

High Mobility Group A1/2 Chromatin Remodeling Proteins Associate with Polycythemia Vera Transformation to Acute Leukemia in Humans and a JAK2 V617F Transgenic Mouse Model

Linda Resar, MD, Donna Marie Williams, PhD, Zhizhuang Joe Zhao, PhD, Ophelia Rogers, Lingling Xian, MD PhD, Jerry L. Spivak, MD, Alison R Moliterno, MD

Blood (2016) 128 (22): 1958.

https://doi.org/10.1182/blood.V128.22.1958.1958

Published: 2016

Journal Articles

The JAK2 V617F Stem Cell Burden Is Mosaic, Dynamic and Correlates with Clinical Disease Burden in the MPN: An Exploitable Target

Alison R Moliterno, MD, Donna Marie Williams, PhD, Jonathan M. Gerber, MD, Michael A McDevitt, MD PhD, Ophelia Rogers, Jerry L. Spivak, MD

Blood (2015) 126 (23): 4090.

https://doi.org/10.1182/blood.V126.23.4090.4090

Published: 2015

Journal Articles

Gender Is a Core Modifier of Disease Outcomes and Survival in the MPN

Brady Stein, MD, Jerry L. Spivak, MD, Alison R Moliterno, MD

Blood (2015) 126 (23): 2106.

https://doi.org/10.1182/blood.V126.23.2106.2106

Published: 2015

Journal Articles

MPL SV , a Unique MPN MPL Splice Variant, Provokes a Fulminant Myeloid Leukemia in a JAK2 V617F Transgenic Mouse Model of Polycythemia Vera

Jerry L. Spivak, MD, Donna Marie Williams, PhD, Zhizhuang Joe Zhao, PhD, Ophelia Rogers, Amy S. Duffield, MD PhD, W. David Hankins, PhD, Alison R Moliterno, MD

Blood (2015) 126 (23): 484.

https://doi.org/10.1182/blood.V126.23.484.484

Published: 2015

Journal Articles

Diagnosis and Management of Polycythemia Vera in the Post- JAK2 V617F Discovery Era: A Survey of Practice Patterns

Brady L Stein, MDMHS, Elizabeth M Kander, MD, Zheng Zhou, MD PhD, Michael B. Streiff, MD, Alison R Moliterno, MD, Jerry L. Spivak, MD

Blood (2014) 124 (21): 2172.

https://doi.org/10.1182/blood.V124.21.2172.2172

Published: 2014

Journal Articles

Essential Thrombocytosis: Redefinition in the Genomic Era

Donna M. Williams, PhD, Michael A McDevitt, MD PhD, Brady L Stein, MDMHS, Ophelia Rogers, Michael B. Streiff, MD, David Neal, Sophie Lanzkron, MD MHS, Linda M. S. Resar, MD, Christine O'Keefe, PhD, Jaroslaw P. Maciejewski, MD PhD, Jerry L. Spivak, MD, Alison R. Moliterno, MD

Blood (2014) 124 (21): 3205.

https://doi.org/10.1182/blood.V124.21.3205.3205

Published: 2014

Journal Articles

Single Cell Analysis Of JAK2 V617F Positive MPN Stem/Progenitor Cells In Chronic Phase and Leukemic Transformation

Jonathan M. Gerber, MD, Donna M. Williams, PhD, Ophelia Rogers, Sarah Morse, Hao Zhang, Michael A McDevitt, MD, PhD, Richard J. Jones, Jerry L. Spivak, MD, Alison R. Moliterno, MD

Blood (2013) 122 (21): 1609.

https://doi.org/10.1182/blood.V122.21.1609.1609

Published: 2013

Journal Articles

The Natural History Of Polycythemia Vera In Two Diagnostic Eras

Brady L Stein, MD MHS, Zheng Zhou, MD, PhD, Jerry L. Spivak, MD, Alison R. Moliterno, MD

Blood (2013) 122 (21): 4078.

https://doi.org/10.1182/blood.V122.21.4078.4078

Published: 2013

NARROW

The High Mobility Group A1 Chromatin Regulator Is Required for Pathologic Megakaryocyte Development and Progression to Myelofibrosis in JAK2V617F Murine Models

High Mobility Group A1 Chromatin Regulators: Key Epigenetic Switches and Therapeutic Targets Required for Leukemic Transformation in JAK2 Mutant MPN

Worse Outcomes in Males with MPN Are Associated with Qualitative and Quantitative Differences in Non-Driver Mutational Burden

Development of Liver-Specific Thrombopoietin Targeted Sirnas: Impact on Platelet Count, Megakaryocyte Mass, and Hematopoietic Progenitors in Normal and MPN Murine Models

High Mobility Group A1 Chromatin Remodeling Proteins Amplify Inflammatory Networks to Drive Leukemic Transformation in Chronic Myeloproliferative Neoplasia in Humans and JAK2 V617F Transgenic Mouse Models

Independent Association of Male Sex with Presentation and Clinical Outcomes in Myeloproliferative Neoplasms

Myeloproliferative Neoplasms in Pediatrics and Young Adults: Genetic Lesions, Diagnostic Features, and Clinical Outcomes

Mechanism of Escape from LNK Negative Regulation: Constitutively Active JAK2V617F Retains Lysine63-Ubiquitin

High Mobility Group A1 Chromatin Remodeling Proteins: Potential Therapeutic Targets Involved in Polycythemia Vera Transformation to Acute Leukemia in Humans and JAK2 V617F Transgenic Mouse Models

Germline ERBB2 Variants Associate with Myeloproliferative Neoplasms

Generation, Characterization and Genetic Modification of Human iPSCs Containing Calr , MPL and JAK2 Mutations Found in MPN Patients

Multicenter Analysis of Clinical Characteristics and Long-Term Outcomes of Transjugular Intrahepatic Portosystemic Shunt Procedure for MPN-Associated Portal Hypertension

High Mobility Group A1/2 Chromatin Remodeling Proteins Associate with Polycythemia Vera Transformation to Acute Leukemia in Humans and a JAK2 V617F Transgenic Mouse Model

The JAK2 V617F Stem Cell Burden Is Mosaic, Dynamic and Correlates with Clinical Disease Burden in the MPN: An Exploitable Target

Gender Is a Core Modifier of Disease Outcomes and Survival in the MPN

MPL SV , a Unique MPN MPL Splice Variant, Provokes a Fulminant Myeloid Leukemia in a JAK2 V617F Transgenic Mouse Model of Polycythemia Vera

Diagnosis and Management of Polycythemia Vera in the Post- JAK2 V617F Discovery Era: A Survey of Practice Patterns

Essential Thrombocytosis: Redefinition in the Genomic Era

Single Cell Analysis Of JAK2 V617F Positive MPN Stem/Progenitor Cells In Chronic Phase and Leukemic Transformation

The Natural History Of Polycythemia Vera In Two Diagnostic Eras

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American Society of Hematology

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