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Jing Wang, PhD
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Journal Articles

The BET Inhibitor, CPI-0610, Promotes Myeloid Differentiation in Myelofibrosis Patient Bone Marrow and Peripheral CD34+ Hematopoietic Stem Cells

Jennifer A Mertz, PhD, Patricia J Keller, PhD, Rosana D Meyer, MD, Oksana Zavidij, PhD, Jike Cui, PhD, Jean-Jacques Kiladjian, MD PhD, Srdan Verstovsek, MD PhD, Vikas Gupta, MD FRCP, FRCPath, Moshe Talpaz, MD, Claire Harrison, DM, FRCP, FRCPath, Adam J. Mead, MD PhD, Ruben Mesa, MD, John Mascarenhas, MD, Adrian Senderowicz, MD, Gozde Colak, PhD, James Shao, MS, Katarina Luptakova, MD, Jeffrey S Humphrey, MD, Jing Wang, PhD, Patrick Trojer, PhD, Mohamed E Salama, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-138752
Published: 2020
Journal Articles

MANIFEST-2, a Global, Phase 3, Randomized, Double-Blind, Active-Control Study of CPI-0610 and Ruxolitinib Vs. Placebo and Ruxolitinib in JAK-Inhibitor-Naive Myelofibrosis Patients

John Mascarenhas, MD, Claire Harrison, DM, FRCP, FRCPath, Katarina Luptakova, MD, Jessica Christo, MA, Jing Wang, PhD, Jennifer A Mertz, PhD, Gozde Colak, PhD, James Shao, MS, Suresh Bobba, MD, Patrick Trojer, PhD, Adrian Senderowicz, MD, Jeffrey S Humphrey, MD, Srdan Verstovsek, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 43.
https://doi.org/10.1182/blood-2020-140901
Published: 2020
Journal Articles

LSD1 Inhibitor CPI-482 Shows Efficacy and Prolongs Survival in Mouse Models of AML and Post-MPN AML in the Context of Constitutive JAK-STAT Pathway Activation

Raajit K. Rampal, MD PhD, John P. McGrath, PhD, Aishwarya Krishnan, BS, Bing Li, MD, Wenbin Xiao, MD PhD, David Nikom, Jing Wang, PhD, Ross L. Levine, MD, Patrick Trojer, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 50–51.
https://doi.org/10.1182/blood-2020-140186
Published: 2020
Journal Articles

Evaluation of T Cell Compartment By Mass Cytometry Reveals Distinct Patterns of Expression of Exhaustion Markers in Chronic Lymphocytic Leukemia

Muharrem Muftuoglu, MD, Li Li, MD, Duncan Mak, BSc, MPhil, Jared K Burks, PhD, Yuanxin Xi, PhD, Bingqian Hu, MS, Hila Shaim, MD, Nobuhiko Imahashi, MD PhD, Mustafa H Bdiwi, MD, Juan Jimenez, BS, Pinaki P Banerjee, PhD, Francesca Lorraine Wei Inng Lim, MD, Lucila Nassif Kerbauy, MD, Mecit Kaplan, BS, April DePombo, DO, Mayela Carolina Mendt, PhD, Rafet Basar, MD, May Daher, MD, David Costa Marin, MD, Jing Wang, PhD, Michael Andreeff, MD PhD, William G Wierda, MD PhD, Nitin Jain, MD, Philip A Thompson, MBBS, Michael J. Keating, MD, Darius Armstrong James, MD, Richard E Champlin, MD, Elizabeth J Shpall, MD, Katayoun Rezvani, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4283.
https://doi.org/10.1182/blood.V130.Suppl_1.4283.4283
Published: 2017
Journal Articles

Therapeutic Targeting of HDAC3 in FOXO1-Mutant DLBCL

Kristy Stengel, PhD, Srividya Bhaskara, PhD, Jing Wang, PhD, Qi Liu, PhD, Scott Hiebert, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 311.
https://doi.org/10.1182/blood.V130.Suppl_1.311.311
Published: 2017
Journal Articles

Histone Deacetylase Inhibitors Mimic BET Inhibitors and Cause RNA Polymerase Pausing at MYC, KIT, and Other Oncogenes in t(8;21) AML

Pankaj Acharya, PhD, Shilpa Sampathi, PhD, Yue Zhao, PhD, Jing Wang, PhD, Qi Liu, PhD, Kristy Stengel, PhD, Scott Hiebert, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2470.
https://doi.org/10.1182/blood.V130.Suppl_1.2470.2470
Published: 2017
Journal Articles

NK Cell Diversity Influences Outcomes after Cord Blood Transplantation

Li Li, MD, Muharrem Muftuoglu, MD, Han Chen, PhD, Duncan Mak, BSc, MPhil, Jared K Burks, PhD, Rohtesh S. Mehta, MDMPH,MS, Yuanxin Xi, PhD, Jiangxing Lv, BS, Bingqian Hu, MS, Juan Jimenez, BS, Mecit Kaplan, BS, Hila Shaim, MD, Nobuhiko Imahashi, MD PhD, Pinaki P Banerjee, PhD, Lucila Nassif Kerbauy, MD, Mayela Carolina Mendt, PhD, Francesca Lorraine Wei Inng Lim, MD, May Daher, MD, April Depombo, DO, Rafet Basar, MD, Michael Andreeff, MD PhD, Jing Wang, PhD, David Costa Marin, MD, Richard E. Champlin, MD, Elizabeth J Shpall, MD, Katy Rezvani, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1979.
https://doi.org/10.1182/blood.V130.Suppl_1.1979.1979
Published: 2017
Journal Articles

The CDK7 Inhibitor THZ1 Alters RNA Polymerase Dynamics at the 5' and 3' Ends of Genes

Shilpa Sampathi, PhD, Pankaj Acharya, PhD, Yue Zhao, PhD, Jing Wang, PhD, Kristy Stengel, PhD, Qi Liu, PhD, Michael R. Savona, MD, Scott Hiebert, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1195.
https://doi.org/10.1182/blood.V130.Suppl_1.1195.1195
Published: 2017
Journal Articles

BRD4 Degradation By Protacs Represents a More Effective Therapeutic Strategy Than BRD4 Inhibitors in DLBCL

Jing Lu, PhD, Yimin Qian, PhD, Kanak Raina, PhD, Martha Altieri, MS, Hanqing Dong, PhD, Jing Wang, PhD, Xin Chen, PhD, Andrew Crew, PhD, Kevin Coleman, PhD, Craig Crews, PhD, James Winkler, PhD
Journal: Blood
Blood (2015) 126 (23): 2050.
https://doi.org/10.1182/blood.V126.23.2050.2050
Published: 2015
Journal Articles

M281: A Therapeutic Anti-FcRn Blocking Antibody for Rapid Clearance of IgG and IgG Autoantibodies in Immune Cytopenias and Other Auto/Allo-Immune Disease

Leona E Ling, PhD, Sucharita Roy, PhD, Thomas Daly, Edward Cochran, Steven Tyler, Lynn Markowitz, Dorota Bulik, PhD, Amit Choudhury, PhD, James Meador, Viraj Parge, Divya Mekala, PhD, Sandra Sipsey, Srishti Gurnani, Jay Duffner, Stan Lee, Nathaniel Washburn, Robin Meccariello, John Schaeck, Jing Wang, PhD, Birgit Schultes, PhD, Jan L. Hillson, MD, William Avery, MS, MBA, Ganesh V. Kaundinya, PhD, Anthony M. Manning, PhD
Journal: Blood
Blood (2015) 126 (23): 3472.
https://doi.org/10.1182/blood.V126.23.3472.3472
Published: 2015
Journal Articles

Phase 1 Trial Testing Single Agent CUDC-907, a Novel, Oral Dual Inhibitor of Histone Deacetylase (HDAC) and PI3K: Initial Assessment of Patients with Relapsed or Refractory (RR) Diffuse Large B-Cell Lymphoma (DLBCL), Including Double Expressor (DE) Lymphoma

Anas Younes, MD, Jesus G. Berdeja, MD, Manish R. Patel, MD, Kevin R. Kelly, MD PhD, Ian W. Flinn, MD PhD, John F Gerecitano, MD PhD, Sattva S. Neelapu, MD, Amanda R. Copeland, RN, MSN, CNS, Amy Akins, RN, BSN, CCRC, Myles Clancy, Anna Ma, MS, Kaiming Sun, PhD, Ze Tian, PhD, Jing Wang, PhD, Jaye Viner, MD MPH, Yasuhiro Oki, MD
Journal: Blood
Blood (2015) 126 (23): 257.
https://doi.org/10.1182/blood.V126.23.257.257
Published: 2015
Journal Articles

CUDC-907, a Dual HDAC and PI3K Inhibitor, Potentially Targets Cancer Cells and The Microenvironment In Hematological Malignancies

Jing Wang, PhD, Natalie Pursell, PhD, Anna Ma, Ruzanna Atoyan, Maria Samson, Mylissa Borek, Steven DellaRocca, Ling Yin, Da-gong Wang, Brian Zifcak, Guang-xin Xu, Maurizio Voi, MD, Cheng-Jung Lai, PhD
Journal: Blood
Blood (2013) 122 (21): 4930.
https://doi.org/10.1182/blood.V122.21.4930.4930
Published: 2013
Journal Articles

Transvection Mediated by the Translocated Cyclin D1 Gene in Mantle Cell Lymphoma.

Elliot M. Epner, MD, PhD, Hui Liu, PhD, Jing Wang, PhD, Mathew Thayer, PhD
Journal: Blood
Blood (2007) 110 (11): 4156.
https://doi.org/10.1182/blood.V110.11.4156.4156
Published: 2007