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John Brown, PhD
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Journal Articles

Mitochondrial Activity Identifies a Transcriptionally and Functionally Distinct Subset of Aged HSCs with Lineage-Balanced Output

Els Mansell, PhD, Valgardur Sigurdsson, PhD, Elitza Deltcheva, PhD, John Brown, PhD, Chela James, PhD, Kenichi Miharada, PhD, Shamit Soneji, PhD, Jonas Larsson, MD PhD, Tariq Enver, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2480.
https://doi.org/10.1182/blood-2019-124001
Published: 2019
Journal Articles

Activation of CRLF2/IL7RA Signaling in Normal Human Cord Blood Hematopoietic Progenitors Induces Philadelphia-like B-Cell Precursor Pre-Leukemia and Leukemia In Vivo

Ifat Geron, PhD, Angela Maria Savino, PhD, Noa Tal, MD PhD, John Brown, PhD, Virginia A Turati, DPhil, Yu Nee Lee, PhD, Chela James, PhD, Avigail Rein Gil, MD, Yehudit Birger, PhD, Inna Muler, Michal Hameiri, PhD, Victoria Marcu-Malina, PhD, Ute Fischer, PhD, Arndt Borkhardt, MD, Ilan M. Kirsch, MD, Arnon Nagler, MD, Tariq Enver, PhD, Shai Izraeli, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 566.
https://doi.org/10.1182/blood-2018-99-115913
Published: 2018
Journal Articles

A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction As a Developmental Susceptibility to ETV6-RUNX1

Simon E Richardson, MA, MD PhD MRCP, FRPATH, Charlotta Boiers, MDPhD, Alya Zriwil, PhD, Emma Laycock, Virginia A Turati, DPhil, John Brown, PhD, Jason Wray, PhD, Chela James, PhD, Dapeng Wang, PhD, Javier Herrero, PhD, Ewa Sitnicka, PhD, Stefan Karlsson, MD, Andrew J.H. Smith, PhD, Sten Eirik Jacobsen, MDPhD, Tariq Enver, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1218.
https://doi.org/10.1182/blood.V130.Suppl_1.1218.1218
Published: 2017
Journal Articles

Single-Cell Analysis of Clonal Dynamics in Childhood ALL Reveals a Key Role for Transcriptional Intratumor Heterogeneity in Driving Resistance to Chemotherapy

Virginia A Turati, PhD, José Afonso Guerra-Assunção, PhD, John C Ambrose, PhD, John Brown, PhD, Mike Hubank, PhD, Alex Hobbs, PhD, Mark Lynch, PhD, Bernadett Gaal, PhD, Sarah Inglott, Lucia Conde, PhD, Simon Richardson, MD PhD, Javier Herrero, PhD, Sten Eirik Jacobsen, MD PhD, Tariq Enver, PhD
Journal: Blood
Blood (2016) 128 (22): 606.
https://doi.org/10.1182/blood.V128.22.606.606
Published: 2016