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Journal Articles

Single Agent CD45-Targeted Antibody Drug Conjugate Enables Full Mismatch Allogeneic Hematopoietic Stem Cell Transplantation in a Murine HSCT Model

Sharon L. Hyzy, MS, Jennifer L Proctor, BS, Geoff O Gillard, PhD, Katelyn J. Hammond, BS, Ganapathy N. Sarma, PhD, Asim Saha, PhD, Nicholas Clark, PhD, Anjali Bhat, MS, Tahirih L Lamothe, BS, Rahul Palchaudhuri, PhD, Bradley R Pearse, PhD, Charlotte F McDonagh, PhD, Hans-Peter Kiem, MDPhD, John E Wagner, MD, Bruce R. Blazar, MD, Anthony E Boitano, PhD, Michael P Cooke, PhD, John C. Davis, Jr., MD MPH, MS

Blood (2020) 136 (Supplement 1): 31.

https://doi.org/10.1182/blood-2020-140489

Published: 2020

Journal Articles

Predictors and Outcomes of Flares in Chronic Graft-Versus-Host Disease

Grigori Okoev, MD PhD, Daniel J. Weisdorf, MD, John E Wagner, MD, Bruce R. Blazar, MD, Margaret L. MacMillan, MD, Todd E. DeFor, MS, Aleksandr Lazaryan, MDPhDMPH, Najla H El Jurdi, MD, Shernan G Holtan, MD, Claudio G. Brunstein, MD PhD, Brian C. Betts, MD, Takuto Takahashi, MD, Veronika Bachanova, MD PhD, Erica D. Warlick, MD, Armin Rashidi, MD PhD, Mukta Arora, MD

Blood (2020) 136 (Supplement 1): 47–48.

https://doi.org/10.1182/blood-2020-136479

Published: 2020

Journal Articles

Gene Therapy for Fanconi Anemia, Complementation Group a: Updated Results from Ongoing Global Clinical Studies of RP-L102

Agnieszka Czechowicz, MDPhD, Rajni Agarwal, MD, Julián Sevilla, MD PhD, Paula Río, PhD, Susana Navarro, PhD, Brian C Beard, PhD, Kenneth M Law, PhD, Grace Choi, BS, Miriam Zeini, PhD, Eileen Nicoletti, MD, John E Wagner, MD, Claire Booth, MBBS, PhD MSc, Jonathan D Schwartz, MD, Juan A Bueren, PhD, Maria Grazia Roncarolo, MD

Blood (2020) 136 (Supplement 1): 14.

https://doi.org/10.1182/blood-2020-137106

Published: 2020

Journal Articles

Romiplostim Improves Platelet Recovery after UCB Transplant

Georgios E. Christakopoulos, MD, Todd E. DeFor, MS, Stefanie M Hage, RN, John E. Wagner, MD, Michael A. Linden, MD PhD, Claudio G Brunstein, MD PhD, Nelli Bejanyan, MD, Michael R Verneris, MD, Angela R. Smith, MD MS

Blood (2019) 134 (Supplement_1): 1979.

https://doi.org/10.1182/blood-2019-125424

Published: 2019

Journal Articles

Outcomes of Chronic Graft-Versus-Host Disease (cGVHD) Following Matched Sibling Donor (MSD) Versus Umbilical Cord Blood Transplant (UCBT)

Grigori Okoev, MD PhD, Daniel J. Weisdorf, MD, John E. Wagner, MD, Bruce R. Blazar, MD, Margaret L. MacMillan, MD, Todd E. DeFor, MS, Aleksandr Lazaryan, MDPhDMPH, Najla H El Jurdi, MD, Shernan Holtan, MD, Claudio G Brunstein, MD PhD, Brian C. Betts, MD, Takuto Takahashi, MD, Veronika Bachanova, MD PhD, Erica D. Warlick, MD, Armin Rashidi, MD PhD, Mukta Arora, MD

Blood (2019) 134 (Supplement_1): 2009.

https://doi.org/10.1182/blood-2019-123421

Published: 2019

Journal Articles

Mgta-456, an Aryl Hydrocarbon Receptor (AHR) Antagonist Based Expansion of CD34+ Hematopoietic Stem Cells (HSC), Permits Selection of Better HLA Matched Cord Blood Units (CBUs) and Promotes Faster Neutrophil Recovery and Uniform Engraftment with Potentially Less Acute Graft-Vs-Host Disease (GVHD)

Heather Stefanski, MD PhD, Claudio G Brunstein, MD PhD, David H. McKenna, MD, Darin Sumstad, MLS, Jeffrey S. Miller, MD, Bruce R. Blazar, MD, Todd E. DeFor, MS, Anthony E. Boitano, PhD, Michael P. Cooke, PhD, Glen D. Raffel, MD PhD, John C. Davis, Jr., MD MPH, MS, John E. Wagner, MD

Blood (2019) 134 (Supplement_1): 804.

https://doi.org/10.1182/blood-2019-122329

Published: 2019

Journal Articles

Preliminary Phase 2 Results Demonstrate Engraftment with Minimal Neutropenia with MGTA-456, a CD34 + Expanded Cord Blood (CB) Product in Patients Transplanted for Inherited Metabolic Disorders (IMD)

Paul Orchard, MD, Glen D. Raffel, MD, Carolyn H Condon, MPH, Catherine A Monaghan, Demetra Vernet, Suzanne Tracey Sheirr, Jennifer Braun, RN BSN, Ryan Shanley, M.S, Troy C Lund, MD MS, PhD, Anthony E. Boitano, PhD, Michael P. Cooke, PhD, John C Davis, MD MPH, John E. Wagner, MD

Blood (2018) 132 (Supplement 1): 3467.

https://doi.org/10.1182/blood-2018-99-115102

Published: 2018

Journal Articles

5 Year Health Care Burden after Allogeneic Hematopoietic Stem Cell Transplantation (HSCT): Impact of Graft Source

Jesus Garcia Garcia, BS, Sonya Grillo, Qing Cao, MS, Claudio G Brunstein, MD PhD, Mukta Arora, MD, Margaret L. MacMillan, MD, John E. Wagner, MD, Daniel J. Weisdorf, MD, Shernan G. Holtan, MD

Blood (2018) 132 (Supplement 1): 367.

https://doi.org/10.1182/blood-2018-99-113201

Published: 2018

Journal Articles

Facilitating Resolution of Life-Threatening Acute Graft-Versus-Host Disease By Supplementation of Human Chorionic Gonadotropin and Epidermal Growth Factor (Pregnyl): A Phase I Study

Blood (2018) 132 (Supplement 1): 71.

https://doi.org/10.1182/blood-2018-99-113564

Published: 2018

Journal Articles

Validation of Minnesota Acute GVHD Risk Score and Identification of New Factors Associated with Initial Response to Steroids: Not All GVHD Is Created Equal

Margaret L. MacMillan, MD, Shernan G. Holtan, MD, Armin Rashidi, MD PhD, Todd E. DeFor, MS, Claudio G Brunstein, MD PhD, John E. Wagner, MD, Bruce R. Blazar, MD, Daniel J. Weisdorf, MD

Blood (2018) 132 (Supplement 1): 67.

https://doi.org/10.1182/blood-2018-99-113085

Published: 2018

Journal Articles

Reduced Intensity Conditioned Bone Marrow Transplant with Post-Transplant Cyclophosphamide and Donor-Derived Mesenchymal Stromal Cell Infusions for Recessive Dystrophic Epidermolysis Bullosa

Christen L. Ebens, MD MPH, John A McGrath, MD FRCP, FMedSci, Katsuto Tamai, MD PhD, Hovnanian Alain, MD PhD, John E. Wagner, MD, Megan Riddle, Douglas R Keene, BS, Todd E. DeFor, MS, Rebecca Tryon, MS, Mei Chen, PhD, David T Woodley, MD, Kristin Hook, MD, Jakub L Tolar, MD PhD

Blood (2018) 132 (Supplement 1): 2165.

https://doi.org/10.1182/blood-2018-99-113035

Published: 2018

Journal Articles

Rapid and Robust CD4+ and CD8+ T-, NK-, B- and Monocyte Cell Reconstitution after Nicotinamide-Expanded Cord Blood Transplantation

Jaap Jan Boelens, MD PhD, Coco de Koning, Mitchell E. Horwitz, MD, Guillermo Sanz, Madan Jagasia, MD MS, John E. Wagner, MD, Patrick J. Stiff, MD, Rabi Hanna, MD, Daniela Cilloni, MD PhD, Stefan Nierkens, PhD

Blood (2018) 132 (Supplement 1): 2123.

https://doi.org/10.1182/blood-2018-99-116700

Published: 2018

Journal Articles

Mgta-456 Contains Large Numbers of Expanded Cord Blood (CB) CD34+CD90+ Hematopoietic Stem Cells (HSC) Which Confer All Engraftment Activity and Correlate with Accelerated Neutrophil Recovery after Myeloablative Conditioning in Patients with Hematologic Malignancy

Anthony E. Boitano, PhD, Michael P. Cooke, PhD, Kevin A. Goncalves, PhD, Darin Sumstad, MLS, John E. Wagner, MD

Blood (2018) 132 (Supplement 1): 2083.

https://doi.org/10.1182/blood-2018-99-114988

Published: 2018

Journal Articles

First-in-Human Clinical Trial to Determine the Safety and Potency of Inducible T Regulatory Cells after Allogeneic Hematopoietic Cell Transplantation

Margaret L. MacMillan, MD, Keli Lee Hippen, PhD, David H. McKenna, MD, Todd E. DeFor, MS, Erica D. Warlick, MD, Claudio G Brunstein, MD PhD, Jeffrey S. Miller, MD, Daniel J. Weisdorf, MD, Bruce R. Blazar, MD, John E. Wagner, MD

Blood (2018) 132 (Supplement 1): 2112.

https://doi.org/10.1182/blood-2018-99-113100

Published: 2018

Journal Articles

Nicord Single Unit Expanded Umbilical Cord Blood Transplantation: Final Results of a Multicenter Phase I/ II Trial

Mitchell E. Horwitz, MD, Daniela Cilloni, MD, David Valcarcel, Francesco Frassoni, MD, Jaap Jan Boelens, MD PhD, Madan Jagasia, MD MBBS, MS, John E. Wagner, MD, Jurgen Kuball, MD, Liang Piu Koh, Navneet S. Majhail, MD MS, Patrick J. Stiff, MD, Rabi Hanna, MD, Richard Thomas T. Maziarz, MD, William YK Hwang, MBBS, FRCP, Pau Montesinos, MD PhD, Joanne Kurtzberg, MD, Guillermo Sanz, MD

Blood (2017) 130 (Supplement 1): 847.

https://doi.org/10.1182/blood.V130.Suppl_1.847.847

Published: 2017

Journal Articles

Phase 2 Trials with Mgta-456, Single Cord Blood Units (CBU) Expanded with an Aryl Hydrocarbon Receptor (AHR) Antagonist, Demonstrate Uniform Engraftment and Rapid Hematopoietic Recovery in Patients Following Myeloablative or Non-Myeloablative Conditioning

John E. Wagner, MD, Claudio G Brunstein, MD PhD, Todd E. DeFor, MS, Anthony E. Boitano, PhD, David McKenna, MD, Darin Sumstad, MLS, Bastiano Sanna, Conrad Bleul, Michael P Cooke, PhD

Blood (2017) 130 (Supplement 1): 662.

https://doi.org/10.1182/blood.V130.Suppl_1.662.662

Published: 2017

Journal Articles

First-in-Human Clinical Trial of the IL-15 Super-Agonist Complex ALT-803 for Patients Relapsed after Allogeneic Hematopoietic Cell Transplantation

Rizwan Romee, MD, Sarah Cooley, MD, Melissa Berrien-Elliott, PhD, Peter Westervelt, MDPhD, Michael R Verneris, MD, John E. Wagner, MD, Daniel J. Weisdorf, MD, Bruce Blazar, MD, John F DiPersio, MD PhD, Amanda F. Cashen, MD, Emily K Jeng, Amy Rock, Hing C Wong, PhD, Todd A. Fehniger, MDPhD, Jeffrey S. Miller, MD

Blood (2017) 130 (Supplement 1): 274.

https://doi.org/10.1182/blood.V130.Suppl_1.274.274

Published: 2017

Journal Articles

HHV-6 Prophylaxis with Foscanet Improves Hematopoietic Engraftment after Umbilical Cord Blood Transplantation

Nelli Bejanyan, MD, John Rogosheske, PharmD, Todd E. DeFor, MS, Jaime Green, MD, Troy C Lund, MD PhD, Daniel J. Weisdorf, MD, John E. Wagner, MD, Claudio G Brunstein, MD PhD

Blood (2017) 130 (Supplement 1): 1951.

https://doi.org/10.1182/blood.V130.Suppl_1.1951.1951

Published: 2017

Journal Articles

Pre-Transplant Exhausted Marrow Infiltrating T Lymphocytes in MRD Negative Patients with Acute Leukemia Predict Early Relapse Following Allogeneic Hematopoietic Stem Cell Transplantation

Robin Williams, MDMS, Sarah Cooley, MD, Peter M. Gordon, MDPhD, Veronika Bachanova, MD PhD, Daniel J. Weisdorf, MD, Bruce Blazar, MD, John E. Wagner, MD, Jeffrey S. Miller, MD, Michael R Verneris, MD

Blood (2017) 130 (Supplement 1): 1997.

https://doi.org/10.1182/blood.V130.Suppl_1.1997.1997

Published: 2017

Journal Articles

Umbilical Cord Blood (UCB) Transplantation in Children with Acute Leukemia: Impact of Conditioning Regimen on Transplant Outcomes

Mary Eapen, MBBS, Joanne Kurtzberg, MD, Mei-Jie Zhang, PhD, Adam M. Mendizabal, PhD, Ka Wah Chang, MD, Michel Duval, MD, Mingwei Fei, MS, Steven Neudorf, MD, Satiro N. De Oliveira, MD, Donna A. Wall, MD, Kirk R. Schultz, MD, Mary M Horowitz, MD MS, John E. Wagner, MD

Blood (2016) 128 (22): 1231.

https://doi.org/10.1182/blood.V128.22.1231.1231

Published: 2016

NARROW

Single Agent CD45-Targeted Antibody Drug Conjugate Enables Full Mismatch Allogeneic Hematopoietic Stem Cell Transplantation in a Murine HSCT Model

Predictors and Outcomes of Flares in Chronic Graft-Versus-Host Disease

Gene Therapy for Fanconi Anemia, Complementation Group a: Updated Results from Ongoing Global Clinical Studies of RP-L102

Romiplostim Improves Platelet Recovery after UCB Transplant

Outcomes of Chronic Graft-Versus-Host Disease (cGVHD) Following Matched Sibling Donor (MSD) Versus Umbilical Cord Blood Transplant (UCBT)

Mgta-456, an Aryl Hydrocarbon Receptor (AHR) Antagonist Based Expansion of CD34+ Hematopoietic Stem Cells (HSC), Permits Selection of Better HLA Matched Cord Blood Units (CBUs) and Promotes Faster Neutrophil Recovery and Uniform Engraftment with Potentially Less Acute Graft-Vs-Host Disease (GVHD)

Preliminary Phase 2 Results Demonstrate Engraftment with Minimal Neutropenia with MGTA-456, a CD34 + Expanded Cord Blood (CB) Product in Patients Transplanted for Inherited Metabolic Disorders (IMD)

5 Year Health Care Burden after Allogeneic Hematopoietic Stem Cell Transplantation (HSCT): Impact of Graft Source

Facilitating Resolution of Life-Threatening Acute Graft-Versus-Host Disease By Supplementation of Human Chorionic Gonadotropin and Epidermal Growth Factor (Pregnyl): A Phase I Study

Validation of Minnesota Acute GVHD Risk Score and Identification of New Factors Associated with Initial Response to Steroids: Not All GVHD Is Created Equal

Reduced Intensity Conditioned Bone Marrow Transplant with Post-Transplant Cyclophosphamide and Donor-Derived Mesenchymal Stromal Cell Infusions for Recessive Dystrophic Epidermolysis Bullosa

Rapid and Robust CD4+ and CD8+ T-, NK-, B- and Monocyte Cell Reconstitution after Nicotinamide-Expanded Cord Blood Transplantation

Mgta-456 Contains Large Numbers of Expanded Cord Blood (CB) CD34+CD90+ Hematopoietic Stem Cells (HSC) Which Confer All Engraftment Activity and Correlate with Accelerated Neutrophil Recovery after Myeloablative Conditioning in Patients with Hematologic Malignancy

First-in-Human Clinical Trial to Determine the Safety and Potency of Inducible T Regulatory Cells after Allogeneic Hematopoietic Cell Transplantation

Nicord Single Unit Expanded Umbilical Cord Blood Transplantation: Final Results of a Multicenter Phase I/ II Trial

Phase 2 Trials with Mgta-456, Single Cord Blood Units (CBU) Expanded with an Aryl Hydrocarbon Receptor (AHR) Antagonist, Demonstrate Uniform Engraftment and Rapid Hematopoietic Recovery in Patients Following Myeloablative or Non-Myeloablative Conditioning

First-in-Human Clinical Trial of the IL-15 Super-Agonist Complex ALT-803 for Patients Relapsed after Allogeneic Hematopoietic Cell Transplantation

HHV-6 Prophylaxis with Foscanet Improves Hematopoietic Engraftment after Umbilical Cord Blood Transplantation

Pre-Transplant Exhausted Marrow Infiltrating T Lymphocytes in MRD Negative Patients with Acute Leukemia Predict Early Relapse Following Allogeneic Hematopoietic Stem Cell Transplantation

Umbilical Cord Blood (UCB) Transplantation in Children with Acute Leukemia: Impact of Conditioning Regimen on Transplant Outcomes

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American Society of Hematology

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American Society of Hematology

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