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Journal Articles

Mechanism of Thrombocytopenia Induced by Anti-CD40 Ligand Immune Complexes and the Prevalence of CD40 Ligand Autoantibodies in Patients with Thrombotic Autoimmune Disorders

Ali Amirkhosravi, Ph.D., Todd V Meyer, Ph.D., Liza Robles-Carillo, MS, Monica Davila, Ph.D., Florian Langer, MD, Hina Desai, MS, Patricia Weinstein, RN, Mildred Amaya, MS, Eduardo Reyes, MS, John L Francis, Ph.D.

Blood (2008) 112 (11): 2857.

https://doi.org/10.1182/blood.V112.11.2857.2857

Published: 2008

Journal Articles

Bevacizumab Immune Complexes Induce Thrombocytopenia and Thrombosis in Mice Transgenic for Human IgG Receptor FcYIIa

Ali Amirkhosravi, Ph.D., Todd V Meyer, Ph.D., Liza Robles-Carillo, MS, Florian Langer, MD, Theresa Robson, BS, Hina Desai, MS, Monica Davila, Ph.D., Mildred Amaya, MS, John L. Francis, Ph.D.

Blood (2008) 112 (11): 114.

https://doi.org/10.1182/blood.V112.11.114.114

Published: 2008

Journal Articles

High-Dose Calcitriol Modulates the Expression and Activity of Tissue Factor and Thrombomodulin in Tumor Cells.

Enriqueta Coll-Sangrona, PhD, Ali Amirkhosravi, Ph.D., Alshad S. Lalani, Ph.D., Liza Robles, M.S., Hina Desai, M.S., Mildred Amaya, M.S., John L. Francis, Ph.D.

Blood (2007) 110 (11): 921.

https://doi.org/10.1182/blood.V110.11.921.921

Published: 2007

Journal Articles

Hypercoagulability in Ovarian Cancer Revisited: A Prospective Analysis of Coagulation and Platelet Activation Markers.

Ali Amirkhosravi, PhD, Glenn Bigsby, IV, D.O., Hina Desai, M.S., Mildred Amaya, M.S., Enriqueta Coll, Ph.D., Liza Robles, M.S., Patricia Faust, R.N., Florian Langer, M.D., Alane Drexler, R.N., Edward Reyes, M.S., John L. Francis, Ph.D.

Blood (2006) 108 (11): 1762.

https://doi.org/10.1182/blood.V108.11.1762.1762

Published: 2006

Journal Articles

Platelet Activation by a Humanized Monoclonal CD40 Ligand (CD40L) Antibody.

Todd Meyer, PhD, Ali Amirkhosravi, Ph.D., Theresa Robson, B.A., Mildred Amaya, M.S., Desai Hina, M.S., Lihe Su, Ph.D., Yen-Ming Hsu, Ph.D., Florian Langer, M.D., John L. Francis, Ph.D.

Blood (2006) 108 (11): 1516.

https://doi.org/10.1182/blood.V108.11.1516.1516

Published: 2006

Journal Articles

Targeting Angiogenesis in Cancer: Bevacizumab-Induced Platelet Activation as a Possible Cause for Unexpected Arterial Thromboembolic Events in Clinical Trials.

Todd Meyer, PhD, Theresa Robson, B.S., Ali Amirkhosravi, Ph.D., Florian Langer, M.D., Hina Desai, M.S., Mildred Amaya, M.S., Pierre Elias, John L. Francis, Ph.D.

Blood (2006) 108 (11): 1091.

https://doi.org/10.1182/blood.V108.11.1091.1091

Published: 2006

Journal Articles

Blood-Borne, but Not Endothelial CD40 Promotes Experimental Lung Metastasis.

Ali Amirkhosravi, PhD, Susan B. Ingersoll, Ph.D., Theresa Robson, BS, Florian Langer, M.D., Jamie Walker, BS, John L. Francis, Ph.D.

Blood (2006) 108 (11): 1092.

https://doi.org/10.1182/blood.V108.11.1092.1092

Published: 2006

Journal Articles

Successful Use of Bivalirudin in the Treatment of Patients Suspected, or at Risk of, Heparin-Induced Thrombocytopenia.

John L. Francis, Ph.D., Alane Drexler, M.S., Gage Gwyn, Rebecca Moroose, M.D.

Blood (2004) 104 (11): 4077.

https://doi.org/10.1182/blood.V104.11.4077.4077

Published: 2004

Journal Articles

Comparison of Clinical Outcomes in Patients with Heparin-Induced Thrombocytopenia Treated with Direct Thrombin Inhibitors.

John L. Francis, Ph.D., Ranjeev Sandhu, Pharm.D., Alane Drexler, M.S., John Dougherty, Pharm.D.

Blood (2004) 104 (11): 3942.

https://doi.org/10.1182/blood.V104.11.3942.3942

Published: 2004

Journal Articles

The Relationship between Systemic Anticoagulation during Cardiac Surgery and Heparin Platelet Factor 4 Antibody Formation.

John L. Francis, Ph.D., Alane Drexler, M.S., Jamie Walker, B.Sc., Kristin Rathmann, MT(ASCP)

Blood (2004) 104 (11): 3951.

https://doi.org/10.1182/blood.V104.11.3951.3951

Published: 2004

Journal Articles

Functional Consequences of Cellular Interactions with Heparin-PF4 Antibodies in Heparin-Induced Thrombocytopenia.

Sarfraz Ahmad, Ph.D., Ali Amirkhosravi, Ph.D., Jamie M. Walker, B.S., Hina Desai, M.S., Mildred Amaya, M.S., Farooq A. Siddiqui, Ph.D., John L. Francis, Ph.D.

Blood (2004) 104 (11): 3498.

https://doi.org/10.1182/blood.V104.11.3498.3498

Published: 2004

Journal Articles

Genetic Evidence That CD154 (CD40 Ligand) Plays a Pathophysiologic Role in the Systemic Coagulopathy Associated with Murine Models of Experimental Metastasis and Endotoxemia.

Susan B. Ingersoll, Ph.D., Ali Amirkhosravi, Ph.D., Florian Langer, M.D., Jamie Walker, Todd Meyer, Ph.D., Mildred Amaya, John L. Francis, Ph.D.

Blood (2004) 104 (11): 2975.

https://doi.org/10.1182/blood.V104.11.2975.2975

Published: 2004

Journal Articles

Frequency of Heparin-Platelet Factor 4 Antibodies among Patients with Acute Coronary Syndromes Presenting to the Emergency Department.

John L. Francis, Ph.D., Alane Drexler, M.S., Jamie Walker, B.Sc., Mary Kathryn Duncan, R.N., Sarfraz Ahmad, Ph.D.

Blood (2004) 104 (11): 2067.

https://doi.org/10.1182/blood.V104.11.2067.2067

Published: 2004

NARROW

Mechanism of Thrombocytopenia Induced by Anti-CD40 Ligand Immune Complexes and the Prevalence of CD40 Ligand Autoantibodies in Patients with Thrombotic Autoimmune Disorders

Bevacizumab Immune Complexes Induce Thrombocytopenia and Thrombosis in Mice Transgenic for Human IgG Receptor FcYIIa

High-Dose Calcitriol Modulates the Expression and Activity of Tissue Factor and Thrombomodulin in Tumor Cells.

Hypercoagulability in Ovarian Cancer Revisited: A Prospective Analysis of Coagulation and Platelet Activation Markers.

Platelet Activation by a Humanized Monoclonal CD40 Ligand (CD40L) Antibody.

Targeting Angiogenesis in Cancer: Bevacizumab-Induced Platelet Activation as a Possible Cause for Unexpected Arterial Thromboembolic Events in Clinical Trials.

Blood-Borne, but Not Endothelial CD40 Promotes Experimental Lung Metastasis.

Successful Use of Bivalirudin in the Treatment of Patients Suspected, or at Risk of, Heparin-Induced Thrombocytopenia.

Comparison of Clinical Outcomes in Patients with Heparin-Induced Thrombocytopenia Treated with Direct Thrombin Inhibitors.

The Relationship between Systemic Anticoagulation during Cardiac Surgery and Heparin Platelet Factor 4 Antibody Formation.

Functional Consequences of Cellular Interactions with Heparin-PF4 Antibodies in Heparin-Induced Thrombocytopenia.

Genetic Evidence That CD154 (CD40 Ligand) Plays a Pathophysiologic Role in the Systemic Coagulopathy Associated with Murine Models of Experimental Metastasis and Endotoxemia.

Frequency of Heparin-Platelet Factor 4 Antibodies among Patients with Acute Coronary Syndromes Presenting to the Emergency Department.

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