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John Letterio
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Journal Articles

Targeting NLRP3 Inflammasome-Induced Therapy Resistance in ALL

Zhongbo Hu, MD PhD, Michael Sporn, MD, John Letterio, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 46.
https://doi.org/10.1182/blood-2020-137520
Published: 2020
Journal Articles

Preclinical Studies and Phase I Trial of Vactosertib in Combination with Pomalidomide in Relapsed Multiple Myeloma: A Corticosteroid-Free Approach By Targeting TGF-β Signaling Pathway

Ehsan Malek, MD, Sunjin Hwang, MD, Marcos de Lima, MD, Paolo Caimi, MD, Molly M Gallogly, MD PhD, Leland Metheny, III, MD, Folashade Otegbeye, MBBChir,MPH, Benjamin K. Tomlinson, MD, Kirsten M Boughan, DO, Brenda Cooper, MD, James Driscoll, MD PhD, John Letterio, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3232.
https://doi.org/10.1182/blood-2019-126728
Published: 2019
Journal Articles

Preclinical Studies and a Phase I Trial of the TGF-β Receptor Inhibitor, Vactosertib (TEW-7197), in Combination with Pomalidomide in Patients with Multiple Myeloma Refractory to Bortezomib or Lenalidomide

Ehsan Malek, MD, Byung-Gyu Kim, PhD DVM, Jason Valent, MD, James Driscoll, MD PhD, Paolo Caimi, MD, Seong-Jin Kim, PhD, Marcos de Lima, MD, John Letterio, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1962.
https://doi.org/10.1182/blood-2018-99-112449
Published: 2018
Journal Articles

Vactosertib, a TGF-ß Receptor I Kinase/ALK5 Inhibitor, Diminishes Tumor Progression and Bone Disease in a Mouse Model of Multiple Myeloma and Overcomes Resistance to Proteasome Inhibitors

Byung-Gyu Kim, PhD DVM, Sung Hee Choi, PhD, George Luo, Olga Sergeeva, PhD, Zhenghong Lee, PhD, James Driscoll, MD PhD, Marcos de Lima, MD, Rose Beck, MD PhD, Seong-Jin Kim, PhD, John Letterio, MD, Ehsan Malek, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1918.
https://doi.org/10.1182/blood-2018-99-117852
Published: 2018
Journal Articles

O -Fucose and Fringe-Modified Recombinant Notch Peptides As Decoy Molecules to Promote Hematopoietic Progenitor Mobilization

Lan Zhou, MD, Shuiliang Yu, PhD, Weihuan Wang, MD PhD, Marwah Albakri, Seunghwan Lim, Chris Siebel, PhD BA, Hillard M Lazarus, MD, John Letterio, MD, Wei Xin, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1903.
https://doi.org/10.1182/blood.V130.Suppl_1.1903.1903
Published: 2017