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Journal Articles

Premature Senescence in Hematopoietic Stem and Progenitor Cells in Ribosomopathy-Associated Bone Marrow Failure Syndromes

Hengjun Chao, MD, Johnson M. Liu, MD

Blood (2015) 126 (23): 298.

https://doi.org/10.1182/blood.V126.23.298.298

Published: 2015

Journal Articles

Pomalidomide Transcriptionally Reprograms Adult Erythroid Progenitors Independently of Ikaros Proteasomal Degradation

Brian M. Dulmovits, MS, Abena O. Appiah-Kubi, MD, Julien Papoin, MS, John Hale, PhD, Mingzhu He, PhD, Yousef Al-Abed, MD, Steven L. Allen, MD, Naomi Taylor, MD PhD, Philippe Marambaud, PhD, Xiuli An, MD PhD, Patrick G. Gallagher, MD, Narla Mohandas, DSc, Jeffrey M. Lipton, MD PhD, Johnson M. Liu, MD, Lionel Blanc, PhD

Blood (2015) 126 (23): 160.

https://doi.org/10.1182/blood.V126.23.160.160

Published: 2015

Journal Articles

Pomalidomide Modulates Transcription Networks Regulating Human Erythropoiesis and Globin Switching: Implications for Treatment of Hemoglobinopathies

Brian M. Dulmovits, MS, Abena O. Appiah-Kubi, MD, Julien Papoin, MS, Michael Gould, BA, Xiuli An, MD PhD, Narla Mohandas, D.Sc., Patrick G. Gallagher, MD, Jeffrey M. Lipton, MD PhD, Johnson M. Liu, MD, Lionel Blanc, PhD

Blood (2014) 124 (21): 1375.

https://doi.org/10.1182/blood.V124.21.1375.1375

Published: 2014

Journal Articles

Primitive Erythropoiesis and Osteogenesis Are Differentially Impaired In Rpl5 and Rps19 Mutant Murine Embryonic Stem Cell Models Of Diamond Blackfan Anemia

Brian M. Dulmovits, BA, MS, Sharon A. Singh, MD, Tracie Goldberg, MD, Sebastien Didier, MSc, Jeffrey M. Lipton, MD, PhD, Lionel Blanc, PhD, Johnson M. Liu, MD

Blood (2013) 122 (21): 3704.

https://doi.org/10.1182/blood.V122.21.3704.3704

Published: 2013

Journal Articles

Pomalidomide Augments Fetal Hemoglobin Production In Primary Erythroid Cells By a Novel Mechanism Modulating BCL11A But Not KLF-1

Abena O. Appiah-Kubi, MD, Lionel Blanc, PhD, Sharon A. Singh, MD, Sebastien Didier, MSc, Sehba Dsilva, MD, Kyle W.H. Chan, PhD, Jeffrey Michael Lipton, MD, PhD, Johnson M. Liu, MD

Blood (2013) 122 (21): 314.

https://doi.org/10.1182/blood.V122.21.314.314

Published: 2013

Journal Articles

HMGB1 Is a Key Modulator Of Stress Erythropoiesis During Sepsis

Sergio I Valdés-Ferrer, MD, Lionel Blanc, PhD, Sebastien Didier, MSc, Johnson M. Liu, MD, Jeffrey M. Lipton, MD, PhD, Sangeeta S Chavan, PhD, Kevin J Tracey, MD

Blood (2013) 122 (21): 8.

https://doi.org/10.1182/blood.V122.21.8.8

Published: 2013

Journal Articles

RASA3 Plays a Critical, Conserved Role in Erythroid Differentiation

Lionel Blanc, PhD, Steven L. Ciciotte, MS, Jeffrey Michael Lipton, MD, PhD, Johnson M. Liu, MD, Luanne L. Peters, PhD

Blood (2012) 120 (21): 3186.

https://doi.org/10.1182/blood.V120.21.3186.3186

Published: 2012

Journal Articles

Suppression of the Hematopoietic Defect in TF-1 Cells Depleted of Shwachman-Diamond Syndrome Protein: Correlation with Decreased eIF6 Levels

Sharon Singh, MD, Lionel Blanc, PhD, Adrianna Henson, Gulay Sezgin, MD, Steven R Ellis, PhD, Johnson M. Liu, MD

Blood (2012) 120 (21): 1270.

https://doi.org/10.1182/blood.V120.21.1270.1270

Published: 2012

Journal Articles

Knockdown of p53 Improves Hematopoietic and Erythroid Differentiation Defects in Mouse Embryonic Stem Cell Models of Diamond Blackfan Anemia

Tracie A. Goldberg, MD, Sharon Singh, MD, Jonathan Solaimanzadeh, Jeffrey Goldstein, Jeffrey Michael Lipton, MD, PhD, Johnson M. Liu, MD

Blood (2011) 118 (21): 728.

https://doi.org/10.1182/blood.V118.21.728.728

Published: 2011

Journal Articles

Mitochondrial Dysfunction As a Potential Source of Reactive Oxygen Species in Cellular Models of Shwachman-Diamond Syndrome

Adrianna Henson, Joseph B Moore, IV, PhD, Johnson M. Liu, MD, Steven Ellis, PhD

Blood (2011) 118 (21): 1343.

https://doi.org/10.1182/blood.V118.21.1343.1343

Published: 2011

Journal Articles

5q- Myelodysplastic Syndrome, In One of 23 Children Lacking a Known Ribosomal Gene Mutation, Masquerading as Diamond Blackfan Anemia (DBA) and Responding to Lenalidomide

Adrianna Vlachos, MD, Jason Farrar, MD, Eva Atsidaftos, MS, Ellen Muir, RN, CNS, Thomas C. Markello, MD, PhD, Sharon Singh, MD, Johnson M. Liu, MD, Steven Ellis, PhD, Robert J. Arceci, MD, PhD, David M. Bodine, PhD, Jeffrey Michael Lipton, MD, PhD

Blood (2010) 116 (21): LBA-2.

https://doi.org/10.1182/blood.V116.21.LBA-2.LBA-2

Published: 2010

Journal Articles

Unique Primitive Erythropoiesis Defect In Rpl5-Deficient Murine Embryonic Stem Cell Model of Diamond Blackfan Anemia

Tracie A. Goldberg, MD, Sharon Singh, MD, Adrianna Henson, Abdallah Nihrane, PhD, Jeffrey Michael Lipton, MD, PhD, Steven Ellis, PhD, Johnson M. Liu, MD

Blood (2010) 116 (21): 877.

https://doi.org/10.1182/blood.V116.21.877.877

Published: 2010

Journal Articles

Pediatric Leukemia-Specific miRNA Expression Profiles Induced by the Leukemic Stem Cell Niche

Sarah Rivkah Vaiselbuh, MD, Houman Khalili, Annette Lee, PhD, Peter Gregersen, MD, Jeffrey Michael Lipton, MD, PhD, Johnson M. Liu, MD

Blood (2010) 116 (21): 942.

https://doi.org/10.1182/blood.V116.21.942.942

Published: 2010

Journal Articles

5q- Syndrome In a Child: Is This Acquired Diamond Blackfan Anemia (DBA)?

Adrianna Vlachos, MD, Jason Farrar, MD, Eva Atsidaftos, MS, Ellen Muir, MSN, CNS, Thomas C. Markello, MD, PhD, Sharon Singh, MD, Johnson M. Liu, MD, Steven Ellis, PhD, Robert J. Arceci, MD, PhD, David M. Bodine, PhD, Jeffrey Michael Lipton, MD, PhD

Blood (2010) 116 (21): 4430.

https://doi.org/10.1182/blood.V116.21.4430.4430

Published: 2010

Journal Articles

Impaired Ribosome Maturation In Human Cells Depleted of Shwachman-Diamond Syndrome Protein SBDS

Gulay Sezgin, MD, Abdallah Nihrane, PhD, Adrianna Henson, Max Wattenberg, Steven Ellis, PhD, Johnson M. Liu, MD

Blood (2010) 116 (21): 2242.

https://doi.org/10.1182/blood.V116.21.2242.2242

Published: 2010

Journal Articles

Diamond Blackfan Anemia Defects In Rps19-Mutant Embryonic Stem Cells: Rescue by Gene Replacement but Not Glucocorticoid Treatment

Sharon Singh, MD, Katelyn Melgar, Tracie A. Goldberg, MD, Abdallah Nihrane, PhD, Jeffrey Michael Lipton, MD, PhD, Steven Ellis, PhD, Johnson M. Liu, MD

Blood (2010) 116 (21): 2237.

https://doi.org/10.1182/blood.V116.21.2237.2237

Published: 2010

Journal Articles

Ectopic Human Mesenchymal Stem Cell-Coated Scaffolds Create An In Vivo Leukemia Niche in NOD/SCID Mice.

Sarah Rivkah Vaiselbuh, MD, Morris Edelman, MD, Jeffrey Michael Lipton, MD, PhD, Johnson M. Liu, MD

Blood (2009) 114 (22): 559.

https://doi.org/10.1182/blood.V114.22.559.559

Published: 2009

Journal Articles

Specific Hematopoietic and Erythroid Differentiation Defects in Mouse Embryonic Stem (ES) Cells with Abortive Ribosome Assembly.

Tracie A. Goldberg, MD, Adrianna Henson, Sharon Singh, MD, Abdallah Nihrane, PhD, Jeffrey Michael Lipton, MD, PhD, Steven Ellis, PhD, Johnson M. Liu, MD

Blood (2009) 114 (22): 1088.

https://doi.org/10.1182/blood.V114.22.1088.1088

Published: 2009

Journal Articles

Yeast Models of Diamond Blackfan Anemia and Shwachman Diamond Syndrome Differ in Their Effect on the Synthesis and Function of Ribosomal Subunits.

Steven R Ellis, PhD, Joseph B. Moore, IV, Johnson M. Liu, MD, Robert J. Arceci, MD, PhD, Jason E. Farrar, MD

Blood (2008) 112 (11): 2044.

https://doi.org/10.1182/blood.V112.11.2044.2044

Published: 2008

Journal Articles

Depletion of the Shwachman-Diamond Syndrome Gene Product, SBDS, Leads to Growth Inhibition and Increased Expression of OPG and VEGFA.

Abdallah Nihrane, PhD, Gulay Sezgin, MD, Sehba Dsilva, MD, Steven Ellis, PhD, Johnson M. Liu, MD

Blood (2008) 112 (11): 2045.

https://doi.org/10.1182/blood.V112.11.2045.2045

Published: 2008

NARROW

Premature Senescence in Hematopoietic Stem and Progenitor Cells in Ribosomopathy-Associated Bone Marrow Failure Syndromes

Pomalidomide Transcriptionally Reprograms Adult Erythroid Progenitors Independently of Ikaros Proteasomal Degradation

Pomalidomide Modulates Transcription Networks Regulating Human Erythropoiesis and Globin Switching: Implications for Treatment of Hemoglobinopathies

Primitive Erythropoiesis and Osteogenesis Are Differentially Impaired In Rpl5 and Rps19 Mutant Murine Embryonic Stem Cell Models Of Diamond Blackfan Anemia

Pomalidomide Augments Fetal Hemoglobin Production In Primary Erythroid Cells By a Novel Mechanism Modulating BCL11A But Not KLF-1

HMGB1 Is a Key Modulator Of Stress Erythropoiesis During Sepsis

RASA3 Plays a Critical, Conserved Role in Erythroid Differentiation

Suppression of the Hematopoietic Defect in TF-1 Cells Depleted of Shwachman-Diamond Syndrome Protein: Correlation with Decreased eIF6 Levels

Knockdown of p53 Improves Hematopoietic and Erythroid Differentiation Defects in Mouse Embryonic Stem Cell Models of Diamond Blackfan Anemia

Mitochondrial Dysfunction As a Potential Source of Reactive Oxygen Species in Cellular Models of Shwachman-Diamond Syndrome

5q- Myelodysplastic Syndrome, In One of 23 Children Lacking a Known Ribosomal Gene Mutation, Masquerading as Diamond Blackfan Anemia (DBA) and Responding to Lenalidomide

Unique Primitive Erythropoiesis Defect In Rpl5-Deficient Murine Embryonic Stem Cell Model of Diamond Blackfan Anemia

Pediatric Leukemia-Specific miRNA Expression Profiles Induced by the Leukemic Stem Cell Niche

5q- Syndrome In a Child: Is This Acquired Diamond Blackfan Anemia (DBA)?

Impaired Ribosome Maturation In Human Cells Depleted of Shwachman-Diamond Syndrome Protein SBDS

Diamond Blackfan Anemia Defects In Rps19-Mutant Embryonic Stem Cells: Rescue by Gene Replacement but Not Glucocorticoid Treatment

Ectopic Human Mesenchymal Stem Cell-Coated Scaffolds Create An In Vivo Leukemia Niche in NOD/SCID Mice.

Specific Hematopoietic and Erythroid Differentiation Defects in Mouse Embryonic Stem (ES) Cells with Abortive Ribosome Assembly.

Yeast Models of Diamond Blackfan Anemia and Shwachman Diamond Syndrome Differ in Their Effect on the Synthesis and Function of Ribosomal Subunits.

Depletion of the Shwachman-Diamond Syndrome Gene Product, SBDS, Leads to Growth Inhibition and Increased Expression of OPG and VEGFA.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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