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Jonathan M Flanagan, PhD
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Journal Articles

Novel Genetic Loci That Influence Fetal Hemoglobin Expression in Children with Sickle Cell Anemia

Anu Marahatta, PhD, Thad A. Howard, MS, Susan E. Stuber, MA, Kathryn L McElhinney, BS, Leon Tshilolo, MDPhD, Thomas N. Williams, MDPhD, Peter Olupot-Olupot, MDPhD, Brigida Santos, MD, Chandy C. John, MD MS, Robert Opoka, MMED, Rosa M. Nieves, MD, Rafael Mena, MD, Jasmine Baker, PhD, Teresa Latham, MA, Jonathan M. Flanagan, PhD, Russell E. Ware, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-143025
Published: 2020
Journal Articles

Genetic Variants That Influence Fetal Hemoglobin Expression from Hydroxyurea Treatment

Anu Marahatta, PhD, Jonathan M. Flanagan, PhD, Thad A. Howard, MS, Nicole Mortier, MHS, PA-C, William Schultz, MHS, PA, Kathryn L McElhinney, BS, Leon Tshilolo, MDPhD, Thomas N. Williams, MDPhD, Peter Olupot-Olupot, MDPhD, Brigida Santos, MD, Chandy C. John, MD MS, Robert Opoka, MMED, Rosa M. Nieves, MD, Rafael Mena, MD, Marvin E Reid, MB, BS, PhD, Angela Rankine-Mullings, MBBS, Jasmine Baker, PhD, Patrick T. McGann, MD MS, Banu Aygun, MD, Adam Lane, PhD, George A. Tomlinson, PhD BSc, MSc, Teresa Latham, MA, Susan E. Stuber, MA, Russell E. Ware, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-143139
Published: 2020
Journal Articles

Regulation of Fetal Hemoglobin through the Insulin Signaling Pathway

Alireza Paikari, MD, Yankai Zhang, PhD, Alicia Chang, MD, Ankush Goyal, MA, Evadnie Rampersaud, PhD, Jonathan M. Flanagan, PhD, Mitchell J. Weiss, MD, PhD, Vivien A. Sheehan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 811.
https://doi.org/10.1182/blood-2019-131313
Published: 2019
Journal Articles

A Genetic Variant in GOLGB1 Affects Golgi Function and Stroke Risk in Patients with Sickle Cell Disease

Varshika Kotu, PhD, Julien Dubrelle, PhD, Jasmine Baker, PhD, Katherine Jenson, Bsc, Jonathan M. Flanagan, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3649.
https://doi.org/10.1182/blood-2018-99-119605
Published: 2018
Journal Articles

Pre-Treatment Steady-State Rheology Predicts Response to Hydroxyurea in Patients with Sickle Cell Disease

Alessandro Baldan, PhD, Carly Ginter Summerall, MS, Loretta James, AA, Bogdan R. Dinu, MD, Jonathan M. Flanagan, PhD, Vivien A. Sheehan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3661.
https://doi.org/10.1182/blood.V128.22.3661.3661
Published: 2016
Journal Articles

Genetic Modifiers Influencing the Development of Albuminuria in Children with Sickle Cell Anemia

Beverly A Schaefer, MD, Jonathan M Flanagan, PhD, Banu Aygun, MD, Ofelia A. Alvarez, MD, Stephen C Nelson, MD, Kerri A Nottage, MD MPH, Carla W Roberts, MD, Thad A. Howard, MS, Barry R Davis, MDPhD, Russell E. Ware, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3393.
https://doi.org/10.1182/blood.V126.23.3393.3393
Published: 2015
Journal Articles

Genes Influencing the Development and Severity of Chronic ITP Identified through Whole Exome Sequencing

Jenny M. Despotovic, DO, MS, Linda M. Polfus, PhD, Jonathan M. Flanagan, PhD, Carolyn M. Bennett, Michele P Lambert, MD, Cindy Neunert, MD, Manjusha Kumar, MD, Robert J. Klaassen, MD FRCP, Courtney Thornburg, MD MS, Michael Jeng, MD, Michael Recht, MD PhD, Susan E. Kirk, PA-C, Alexis A. Thompson, MD, Diane J. Nugent, MD, Ellis J. Neufeld, MD PhD, James B. Bussel, MD, Eric Boerwinkle, PhD, Rachael F. Grace, MD
Journal: Blood
Blood (2015) 126 (23): 73.
https://doi.org/10.1182/blood.V126.23.73.73
Published: 2015
Journal Articles

Effects of Genetic Polymorphisms on Leukocyte and Neutrophil Counts and Maximum Tolerated Dose of Hydroxyurea in Children with Sickle Cell Anemia

Beverly A Schaefer, MD, Jonathan M Flanagan, PhD, Thad A. Howard, MS, Kerri A Nottage, MD MPH, Connie M. Piccone, MD, Scott T. Miller, MD, Alex George, MD, PhD, Beatrice E. Gee, MD, Barry R Davis, MDPhD, Russell E. Ware, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2165.
https://doi.org/10.1182/blood.V126.23.2165.2165
Published: 2015
Journal Articles

Genetic Predictors of Hemoglobin F Response to Hydroxyurea in Sickle Cell Anemia

Vivien A Sheehan, MD, PhD, Thad A Howard, MS, Aniko Sabo, PhD, Uma Nagasaswamy, PhD, Jacy R Crosby, MS, Brian Davis, MS, Alexander H Li, MS, Eric Boerwinkle, PhD, Richard A Gibbs, PhD, Russell E. Ware, MD, PhD, Jonathan M Flanagan, PhD
Journal: Blood
Blood (2012) 120 (21): 241.
https://doi.org/10.1182/blood.V120.21.241.241
Published: 2012
Journal Articles

Gene Expression Profiles of Hydroxyurea Tolerant Cell Lines Identify Genetic Mechanisms That Influence Hydroxyurea Maximum Tolerated Dose

Rosa Diaz, MD, Jonathan M Flanagan, PhD, Thad A Howard, MS, Russell E. Ware, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1005.
https://doi.org/10.1182/blood.V120.21.1005.1005
Published: 2012
Journal Articles

Genotoxicity Associated with Hydroxyurea Exposure in Infants with Sickle Cell Anemia: Results From the BABY-HUG Phase III Clinical Trial

Patrick T. McGann, MD, Jonathan M Flanagan, PhD, Thad A Howard, MS, Stephen D Dertinger, PhD, Jin He, MD, Anita S Kulharya, PhD, Bruce W Thompson, PhD, Russell E. Ware, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 8.
https://doi.org/10.1182/blood.V118.21.8.8
Published: 2011
Journal Articles

Assessment of Genotoxicity Associated with Hydroxyurea Therapy in Children with Sickle Cell Anemia.

Jonathan M Flanagan, PhD, Thad A. Howard, MS, Nicole Mortier, MHS, PA-C, Svetlana Avlasevich, B.S., Matthew Smeltzer, MS, Song Wu, PhD, Stephen D. Dertinger, PhD, Russell E. Ware, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 2554.
https://doi.org/10.1182/blood.V114.22.2554.2554
Published: 2009
Journal Articles

Genetic Predictors of Hydroxyurea Response in Children with Sickle Cell Disease.

Jenny McDade, DO, MS, Jonathan M Flanagan, PhD, Nicole Mortier, MHS, PA-C, Matthew Smeltzer, MS, Thad A Howard, MS, Amy Cone, FNP, Jane Hankins, MD, MS, Banu Aygun, MD, Song Wu, PhD, Russell E Ware, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 820.
https://doi.org/10.1182/blood.V114.22.820.820
Published: 2009
Journal Articles

Distinct Phenotypes of Hydroxyurea Absorption among Children with Sickle Cell Anemia

Russell E. Ware, MD, PhD, Jin He, MD, Nicole A. Mortier, MHS, PA-C, Thad A. Howard, MS, Cheng Cheng, PhD, Jonathan M. Flanagan, PhD, Alex Sparreboom, PhD
Journal: Blood
Blood (2008) 112 (11): 709.
https://doi.org/10.1182/blood.V112.11.709.709
Published: 2008
Journal Articles

Analysis of the Effect of Soluble Transferrin Receptor 1 (sTfR1) on Iron Metabolism in Mice.

Jonathan M. Flanagan, PhD, Hongfan Peng, Pauline L. Lee, PhD, Ernest Beutler, MD
Journal: Blood
Blood (2005) 106 (11): 3584.
https://doi.org/10.1182/blood.V106.11.3584.3584
Published: 2005
Journal Articles

The Genetic Basis of Human Erythrocyte Pyridoxal Kinase Activity Variation.

Jonathan M. Flanagan, PhD, Ernest Beutler, M.D.
Journal: Blood
Blood (2004) 104 (11): 1579.
https://doi.org/10.1182/blood.V104.11.1579.1579
Published: 2004