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Joseph L Wiemels, PhD
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Journal Articles

Genetic Determinants of Blood Cell Traits Play a Role in Susceptibility to Acute Lymphoblastic Leukemia

Linda Kachuri, PhD MPH, Soyoung Jeon, BSc, Andrew T. DeWan, PhD, Catherine Metayer, MD PhD, John S. Witte, PhD, Xiaomei Ma, PhD, Charleston W. K. Chiang, PhD, Joseph L. Wiemels, PhD, Adam J. de Smith, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
https://doi.org/10.1182/blood-2020-141443
Published: 2020
Journal Articles

The Genome-Wide Impact of Trisomy 21 on DNA Methylation and Its Implications for Hematologic Malignancies

Joseph L. Wiemels, PhD, Ivo S Muskens, Shaobo Li, Priyatama Pandey, Ritu Roy, PhD, Helen M Hansen, BSc, Kimberly D Siegmund, PhD, Beth A Mueller, PhD, Xiaomei Ma, PhD, Catherine Metayer, MD PhD, Adam J de Smith, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2510.
https://doi.org/10.1182/blood-2019-131455
Published: 2019
Journal Articles

Pediatric Acute Promyelocytic Leukemia in Brazil: Epidemiology, Molecular Features, and Importance of GST-Theta 1 in Chemotherapy Response and Outcome

Francianne G. Andrade, MSc, PhD, Suellen V. M. Feliciano, MSc, PhD, Ingrid Sardou-Cezar, Gisele D. Brisson, MSc, Filipe V. S. Bueno, MSc, Danielle T. Vianna, MD MSc, Eugênia Terra-Granado, MSc, PhD, Ilana Z. Renault, Marceli O. Santos, MSc, PhD, Elda P. Noronha, MSc, PhD, Joseph L. Wiemels, PhD, Maria S. Pombo-de-Oliveira, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5187.
https://doi.org/10.1182/blood-2019-131529
Published: 2019
Journal Articles

Germline GAB2 Mutations in Childhood Acute Lymphoblastic Leukemia

Adam J de Smith, PhD, Geneviève Lavoie, PhD, Kyle M Walsh, PhD, Sumeet Aujla, BSc, Erica Evans, BSc, Helen M Hansen, BSc, Ivan Smirnov, PhD, Alice Y Kang, MPH, Martin Zenker, MD, John J Ceremsak, BSc, Elliot Stieglitz, MD, Roberta McKean-Cowdin, PhD, Catherine Metayer, PhD, Philippe P Roux, PhD, Joseph L Wiemels, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 388.
https://doi.org/10.1182/blood-2018-99-119235
Published: 2018
Journal Articles

Large Multi-Ethnic Genome Wide Association Study Reveals Novel Genetic Associations with Childhood Acute Lymphoblastic Leukemia at Chromosomes 8q24 and 17q12

Adam J. de Smith, PhD, Kyle M. Walsh, PhD, Stephen S. Francis, PhD, Semira Gonseth, MD, Helen M. Hansen, BSc, Ivan Smirnov, PhD, Lisa Barcellos, PhD, Rong Wang, PhD, Andrew T. DeWan, PhD, Catherine Metayer, PhD, Xiaomei Ma, MD PhD, Joseph L. Wiemels, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 30.
https://doi.org/10.1182/blood.V130.Suppl_1.30.30
Published: 2017
Journal Articles

Somatic and Germline Mutational Heterogeneity in High Hyperdiploid Acute Lymphoblastic Leukemia

Adam J de Smith, PhD, Kyle M Walsh, PhD, Ivan Smirnov, PhD, Sumeet Aujla, Erica Sanders, Hansen M Helen, Catherine Metayer, PhD, Joseph L. Wiemels, PhD
Journal: Blood
Blood (2016) 128 (22): 1727.
https://doi.org/10.1182/blood.V128.22.1727.1727
Published: 2016
Journal Articles

Mechanism of IL-10 Protective Effect in Development of Childhood B Cell Acute Lymphoblastic Leukemia

Briana Fitch, Michelle L. Hermiston, MD PhD, Joseph L. Wiemels, PhD, Scott C. Kogan, MD
Journal: Blood
Blood (2016) 128 (22): 4075.
https://doi.org/10.1182/blood.V128.22.4075.4075
Published: 2016
Journal Articles

Characterization of the DNA Methylome during Human B-Cell Differentiation

Marta Kulis, Simon Heath, Giancarlo Castellano, Renée Beekman, Angelika Merkel, Emanuele Raineri, Anna Esteve, Ana C Queirós, Guillem Clot, Ronald Schuyler, Simone Ecker, Vera Pancaldi, Daniel Rico, Lidia Agueda, Julie Blanc, David Richardson, Laura Clarke, Avik Datta, Nuria Russiñol, Marien Pascual, Xavier Aguirre, Felipe Prosper, MD, Diego Alignani, Bruno Paiva, PhD, Gersende Caron, Thierry Fest, MD PhD, Marcus O. Muench, Marina Fomin, Seung-Tae Lee, MD, Joseph L. Wiemels, PhD, Alfonso Valencia, Marta Gut, Paul Flicek, Hendrik G. Stunnenberg, Reiner Siebert, Ralf Küppers, PhD, Ivo G. Gut, Elias Campo, MD, José I. Martín-Subero
Journal: Blood
Blood (2014) 124 (21): 4346.
https://doi.org/10.1182/blood.V124.21.4346.4346
Published: 2014
Journal Articles

Two-Track Epigenetic Remodeling and Backtracking to Embryonic Stem Cell Bivalency in B-Cell Acute Lymphoblastic Leukemias

Seung-Tae Lee, MD, Marcus O. Muench, Marina Fomin, Jianqiao Xiao, Mi Zhou, MD PhD, Adam J. de Smith, PhD, José Martín-Subero, Simon Heath, E. Andres Houseman, Ritu Roy, Margaret R. Wrensch, PhD, John K. Wiencke, PhD, Catherine Metayer, Joseph L. Wiemels, PhD
Journal: Blood
Blood (2014) 124 (21): 3557.
https://doi.org/10.1182/blood.V124.21.3557.3557
Published: 2014
Journal Articles

Missense SNP rs3731249 Explains the CDKN2A Association with Childhood ALL and Shows Risk Allele Selection in Tumors with Somatic CDKN2A Alterations

Adam J. de Smith, PhD, Kyle M. Walsh, PhD, Helen M. Hansen, Lisa F. Barcellos, PhD, Anand P. Chokkalingam, PhD, Robert B. Jenkins, MD PhD, Margaret R. Wrensch, PhD, John K. Wiencke, PhD, Catherine Metayer, MD PhD, Joseph L. Wiemels, PhD
Journal: Blood
Blood (2014) 124 (21): 129.
https://doi.org/10.1182/blood.V124.21.129.129
Published: 2014
Journal Articles

A Novel Functional Polymorphism in the CCAAT/Enhancer Binding Protein (C/EBP), Epsilon (CEBPE) Gene Promoter Influences Acute Lymphoblastic Leukemia Risk Via Interaction with IKZF1

Kyle M. Walsh, PhD, Adam J. de Smith, PhD, Jianqiao Xiao, Marcus O. Muench, Marina Fomin, Helen M. Hansen, Catherine Metayer, Joseph L. Wiemels, PhD
Journal: Blood
Blood (2014) 124 (21): 489.
https://doi.org/10.1182/blood.V124.21.489.489
Published: 2014
Journal Articles

Bone Marrow Microbiome: Metagenomic Comparsion of Childhood Acute Lymphoblastic and Acute Myeloid Leukamias

Stephen Starko Francis, MS, PhD, Jake Wendt, Amelia D. Wallace, MPH, Lee W Riley, MD, Fenyong Liu, PhD, Catherine Metayer, MD PhD, Joseph L. Wiemels, PhD
Journal: Blood
Blood (2014) 124 (21): 3771.
https://doi.org/10.1182/blood.V124.21.3771.3771
Published: 2014
Journal Articles

Genomewide DNA Methylation Analysis Reveals Specific Signatures in Childhood B-Lymphoblastic Leukemias,

Seung-Tae Lee, Yuanyuan Xiao, Marcus O. Muench, Jianqiao Xiao, Ivan Smirnov, Joseph L. Wiemels, PhD
Journal: Blood
Blood (2011) 118 (21): 3476.
https://doi.org/10.1182/blood.V118.21.3476.3476
Published: 2011
Journal Articles

E2a-Pbx1 Direct Targets and Secondary Mutations in Leukemogenesis.

Christofer Diakos, MD, Yuanyuan Xiao, Jerry Hofmann, Shichun Zheng, Michelle Kang, Mi Zhou, John Wiencke, Sheng L. Zhong, PhD, Joseph L. Wiemels, PhD
Journal: Blood
Blood (2008) 112 (11): 3343.
https://doi.org/10.1182/blood.V112.11.3343.3343
Published: 2008
Journal Articles

Genome-Wide Scanning of Epigenomic Alterations in Childhood Leukemia

Sheng L. Zhong, PhD, Yuanyuan Xiao, Ru-Fang Yeh, PhD, Mi Zhou, Margaret R Wrensch, PhD, Shichun Zheng, John Wiencke, Joseph L. Wiemels, PhD
Journal: Blood
Blood (2008) 112 (11): 4464.
https://doi.org/10.1182/blood.V112.11.4464.4464
Published: 2008
Journal Articles

Cytogenetics of Hispanics and Whites with Childhood Acute Lymphoblastic Leukemia in California.

Melinda C. Aldrich, MPH, Luoping Zhang, PhD, Joseph L. Wiemels, PhD, Xiaomei Ma, PhD, Mignon Loh, MD, Steve Selvin, PhD, James Feusner, MD, Martyn T. Smith, PhD, Patricia A. Buffler, PhD
Journal: Blood
Blood (2005) 106 (11): 4536.
https://doi.org/10.1182/blood.V106.11.4536.4536
Published: 2005