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Journal Articles

NKTT120 Safely Depletes iNKT Cells in Stable Adult Sickle Cell Patients in a Phase 1 Trial

Joshua J. Field, MD MS, Elaine M. Majerus, MD PhD, Ken I. Ataga, MD, Elliott P. Vichinsky, MD, Cheryl Eaton, Rosemary Mazanet, MD PhD, David G. Nathan, MD

Blood (2015) 126 (23): 2178.

https://doi.org/10.1182/blood.V126.23.2178.2178

Published: 2015

Journal Articles

Adult Patients with Stable Sickle Cell Disease Prior to Treatment with the iNKT Cell Depleting Antibody NKTT120 Have Consistent and Elevated Numbers of Activated (CD69 + ) iNKT Cells Relative to Healthy Adult Volunteers

Rosemary Mazanet, MD PhD, Robert Schaub, PhD, Felix Scheuplein, PhD, Cheryl A. Eaton, BA, Robert Mashal, MD, Joshua J. Field, MD MS

Blood (2014) 124 (21): 4097.

https://doi.org/10.1182/blood.V124.21.4097.4097

Published: 2014

Journal Articles

Children with Sickle Cell Disease on Chronic Red Cell Transfusion Experience Fewer Hospitalizations for Acute Vaso-Occlusive Episodes Irrespective of the Indication for Transfusion

Carmen C Wallace, MD, Hilda Mata, Nancy J Wandersee, PhD, J. Paul Scott, MD, Amanda M Brandow, DO, MS, Joshua J. Field, MD MS, Matthew Karafin, MD, Cheryl A. Hillery, MD

Blood (2014) 124 (21): 4282.

https://doi.org/10.1182/blood.V124.21.4282.4282

Published: 2014

Journal Articles

Contrast-Enhanced Ultrasound Detects Differences in Microvascular Blood Flow in Adults with Sickle Cell Disease Administered Regadenoson

Jonathan R. Lindner, MD, Michael Widlansky, MD, Melinda D. Wu, MD, Jillian Dargatz, RN, Leanne M. Harmann, RDCS, RDMS, RVT, Todd Belcik, BS, RCS, RDCS, Donna S. Neuberg, ScD, David G. Nathan, MD, Joel Linden, PhD, Joshua J. Field, MD MS

Blood (2014) 124 (21): 2705.

https://doi.org/10.1182/blood.V124.21.2705.2705

Published: 2014

Journal Articles

Higher Levels of Circulating Fibrocytes Are Associated with Lower Oxygen Saturation in Adults with Sickle Cell Disease

Joshua J. Field, MD MS, Borna Mehrad, MD, Marie Burdick, PhD, Kaushik Shahir, MD, Debora Nischik, RN, Pippa Simpson, PhD, Robert Strieter, MD, C. Edward Rose, MD

Blood (2014) 124 (21): 2710.

https://doi.org/10.1182/blood.V124.21.2710.2710

Published: 2014

Journal Articles

NKTT120 Reduces iNKT Cells without Dose Limiting Toxicity in Stable Adult Sickle Cell Patients in a Phase 1 Trial

Elaine M. Majerus, MD PhD, Kenneth I. Ataga, MD, Elliott Vichinsky, MD, Cheryl A. Eaton, BA, Rosemary Mazanet, MD PhD, David G. Nathan, MD, Joshua J. Field, MD MS

Blood (2014) 124 (21): 2718.

https://doi.org/10.1182/blood.V124.21.2718.2718

Published: 2014

Journal Articles

The Role Of NF-κB In The Activation Of Human iNKT Cells In Sickle Cell Disease Patients and In Vitro

Jennifer C. Yu, MD, Gene Lin, MD, PhD, Ruey Ken, PhD, Joshua J. Field, MD, MS, Joel Linden, PhD

Blood (2013) 122 (21): 2291.

https://doi.org/10.1182/blood.V122.21.2291.2291

Published: 2013

Journal Articles

Human Sickle Cell Disease Increases Numbers and Activation Of Peripheral Blood Myeloid Dendritic Cells, Monocytes, and Neutrophils

Gene Lin, MD, PhD, Jennifer C. Yu, MD, Joshua J. Field, MD, MS, David G. Nathan, MD, Joel Linden, PhD

Blood (2013) 122 (21): 1033.

https://doi.org/10.1182/blood.V122.21.1033.1033

Published: 2013

Journal Articles

An Intensive Model Of Care For Adults With Sickle Cell Disease That Rapidly Reduces Hospital Admissions, Readmissions and Cost

Kathryn L. Koch, MSN, FNP-BC, Cynthia L. Leonard, MSN, RN, Katherine Bagemihl, MS, David Marks, MD, MBA, Thomas C. Abshire, Joshua J. Field, MD, MS

Blood (2013) 122 (21): 773.

https://doi.org/10.1182/blood.V122.21.773.773

Published: 2013

Journal Articles

NF-κB Activation Mediates Induction Of Anti-Inflammatory Adenosine A2A Receptors In iNKT Cells Of Sickle Cell Patients During Vaso-Occlusive Episodes and Upon Activation Of Cultured Human iNKT Cells

Joel Linden, PhD, Gene Lin, MD, PhD, Jennifer C. Yu, MD, Donna S. Neuberg, ScD, David G. Nathan, MD, Joshua J. Field, MD, MS

Blood (2013) 122 (21): 975.

https://doi.org/10.1182/blood.V122.21.975.975

Published: 2013

Journal Articles

A Phase I Single Ascending Dose Study Of NKTT120 In Stable Adult Sickle Cell Patients

Joshua J. Field, MD, MS, Kenneth I. Ataga, MD, Elaine Majerus, MD, PhD, Cheryl A. Eaton, BA, Robert Mashal, MD, David G. Nathan, MD

Blood (2013) 122 (21): 977.

https://doi.org/10.1182/blood.V122.21.977.977

Published: 2013

NARROW

NKTT120 Safely Depletes iNKT Cells in Stable Adult Sickle Cell Patients in a Phase 1 Trial

Adult Patients with Stable Sickle Cell Disease Prior to Treatment with the iNKT Cell Depleting Antibody NKTT120 Have Consistent and Elevated Numbers of Activated (CD69 + ) iNKT Cells Relative to Healthy Adult Volunteers

Children with Sickle Cell Disease on Chronic Red Cell Transfusion Experience Fewer Hospitalizations for Acute Vaso-Occlusive Episodes Irrespective of the Indication for Transfusion

Contrast-Enhanced Ultrasound Detects Differences in Microvascular Blood Flow in Adults with Sickle Cell Disease Administered Regadenoson

Higher Levels of Circulating Fibrocytes Are Associated with Lower Oxygen Saturation in Adults with Sickle Cell Disease

NKTT120 Reduces iNKT Cells without Dose Limiting Toxicity in Stable Adult Sickle Cell Patients in a Phase 1 Trial

The Role Of NF-κB In The Activation Of Human iNKT Cells In Sickle Cell Disease Patients and In Vitro

Human Sickle Cell Disease Increases Numbers and Activation Of Peripheral Blood Myeloid Dendritic Cells, Monocytes, and Neutrophils

An Intensive Model Of Care For Adults With Sickle Cell Disease That Rapidly Reduces Hospital Admissions, Readmissions and Cost

NF-κB Activation Mediates Induction Of Anti-Inflammatory Adenosine A2A Receptors In iNKT Cells Of Sickle Cell Patients During Vaso-Occlusive Episodes and Upon Activation Of Cultured Human iNKT Cells

A Phase I Single Ascending Dose Study Of NKTT120 In Stable Adult Sickle Cell Patients

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American Society of Hematology

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American Society of Hematology

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