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Journal Articles

Cigarette Smoke or Cigarette Condensate Exposure Enhances Growth of FLT3-ITD AML Models and Alters DNA Methylation and Leukemic Gene Expression

Mary Figueroa, BS, Maninder Khosla, BS, Yue Lu, PhD, Marcos Estecio, PhD, Seyed Javad Moghaddam, MD, Elias Jabbour, MD, Marina Konopleva, MD PhD, Courtney D. DiNardo, MD MSCE, Joya Chandra, PhD

Blood (2020) 136 (Supplement 1): 29–30.

https://doi.org/10.1182/blood-2020-142478

Published: 2020

Journal Articles

The Impact of Smoking on Survival in Patients (Pts) with Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia (ALL) Treated with the Combination of Intensive Therapy with Tyrosine Kinase Inhibitor (TKI)

Blood (2019) 134 (Supplement_1): 3815.

https://doi.org/10.1182/blood-2019-129396

Published: 2019

Journal Articles

Acceleration of AML Progression By Cigarette Smoke Exposure or Condensate Exposure and Associated DNA Methylation Alterations

Mary Figueroa, BS, Mansour Alfayez, MD, Yue Lu, PhD, Marcos Estecio, PhD, Seyed Javad Moghaddam, MD, Marina Y Konopleva, MD PhD, Elias Jabbour, MD, Courtney D. DiNardo, MDMSc, Joya Chandra, PhD

Blood (2019) 134 (Supplement_1): 2554.

https://doi.org/10.1182/blood-2019-127216

Published: 2019

Journal Articles

Trimethylated H3K27, and Di- and Trimethylated H3K4 Proteomic Profiling Distinguishes Acute Lymphoid Leukemia (ALL) from Acute Myeloid Leukemia (AML) and Associates with Overall Survival and Tyrosine Kinase Inhibitor Sensitivity in Adult ALL

Anneke D. van Dijk, BS, Fieke W Hoff, BSc, Yihua Qiu, Mary Figueroa, BS, Joya Chandra, PhD, Elias Jabbour, MD, Eveline S. de Bont, MD PhD, Steven M. Kornblau, MD

Blood (2019) 134 (Supplement_1): 1460.

https://doi.org/10.1182/blood-2019-124960

Published: 2019

Journal Articles

Targeting the NRF2/HO-1 Antioxidant Pathway with Consequences for Notch Signaling in FLT3-ITD Positive AML: A Novel Therapeutic Approach

Marisa J Hornbaker, B.S., Mary E Irwin, PhD, LaNisha Patterson, B.S., Shelley M Herbrich, MS, Patrick Zweidler-McKay, MD PhD, Joya Chandra, PhD

Blood (2015) 126 (23): 2470.

https://doi.org/10.1182/blood.V126.23.2470.2470

Published: 2015

Journal Articles

Accelerated Degradation of cFLIP Mediated By Inhibition of Methyltransferases Sensitizes B-Cell Lymphoma Cells to TRAIL-Induced Apoptosis

Frank K Braun, PhD, Rohit Mathur, PhD, Lalit Sehgal, PhD, Rachel Wilkie-Grantham, Joya Chandra, PhD, Zuzana Berkova, PhD, Felipe Samaniego, MD

Blood (2014) 124 (21): 920.

https://doi.org/10.1182/blood.V124.21.920.920

Published: 2014

Journal Articles

HDAC and LSD1 Inhibitors Synergize to Induce Cell Death in Acute Leukemia Cells

Lorimar Ramirez, MD, Melissa Singh, PhD, Joya Chandra, PhD

Blood (2011) 118 (21): 1427.

https://doi.org/10.1182/blood.V118.21.1427.1427

Published: 2011

Journal Articles

Small Molecule Inhibitors of HER2 Inhibit Proliferative Signaling and Promote Apoptosis in Ph+ ALL

Mary E Irwin, PhD, Laura Nelson, PhD, Janice M Santiago-O'Farrill, Claudia P Miller, PhD, Doris R. Siwak, PhD, Gordon B. Mills, MD, PhD, Shulin Li, PhD, Dennis P Hughes, MD, PhD, Joya Chandra, PhD

Blood (2011) 118 (21): 1397.

https://doi.org/10.1182/blood.V118.21.1397.1397

Published: 2011

Journal Articles

A Pilot Study Investigating the Relationship Between Diet and Oxidative Stress in Infants Receiving Therapy for Acute Leukemia

Phillip D Knouse, M.S., Mayurika Pise, B.M.M.S., Jalissa N Furr, Rhea Li, BS, MPH, Donna A Bell, M.S.N., RN, FNP, Lisa L Triche, M.S.N., RN, CPNP, Shana L Palla, M.S., Joya Chandra, PhD

Blood (2011) 118 (21): 4228.

https://doi.org/10.1182/blood.V118.21.4228.4228

Published: 2011

Journal Articles

Induction of Oxidative Stress and Glutathione Depletion by ABT-737, a Novel Small Molecule Inhibitor of Bcl-2, Contributes to Cytotoxicity in Leukemia Cells.

Joya Chandra, PhD, Adrienne Howard, Kathleen Jensen, Ray Meyn, Ph.D.

Blood (2007) 110 (11): 4336.

https://doi.org/10.1182/blood.V110.11.4336.4336

Published: 2007

Journal Articles

ERBB Signaling Promotes BCR-Abl Expression and Modulates Multiple Signaling Pathways as Assessed by High-Throughput, Reverse Phase Protein Array.

Laura D. Nelson, PhD, Doris R. Siwak, PhD, Yiling Lu, PhD, Claudia Miller, MS, Joya Chandra, PhD, Dennis P.M. Hughes, MD, PhD

Blood (2006) 108 (11): 4349.

https://doi.org/10.1182/blood.V108.11.4349.4349

Published: 2006

Journal Articles

Fyn Upregulation Is a Novel ROS-Dependent Mechanism Controlling CML Growth, Progression and Imatinib Resistance.

Joya Chandra, PhD, Hesham M. Amin, MD, Adrienne Howard, Claudia P. Miller, MS, Quan Lin, PhD, Kechen Ban, PhD

Blood (2006) 108 (11): 2241.

https://doi.org/10.1182/blood.V108.11.2241.2241

Published: 2006

Journal Articles

Increased Superoxide Levels, HO-1 and Fyn Protein Expression in Bcr/abl Overexpressing Cells: Implications for Adaptation and Survival in an Oxidatively Challenging Environment.

Joya Chandra, PhD, Kechen Ban, PhD

Blood (2005) 106 (11): 4403.

https://doi.org/10.1182/blood.V106.11.4403.4403

Published: 2005

Journal Articles

The Novel, Orally Active Proteasome Inhibitor, NPI-0052, Induces Apoptosis in Leukemia Lymphoma Cell Lines and Patient Specimens.

Claudia P. Miller, MS, Kechen Ban, PhD, Stacey L. Ruiz, Saskia Neuteboom, PhD, Michael Palladino, PhD, David McConkey, PhD, Joya Chandra, PhD

Blood (2005) 106 (11): 241.

https://doi.org/10.1182/blood.V106.11.241.241

Published: 2005

Journal Articles

ERBB Expression in Philadelphia Chromosome-Positive ALL as a Potential Therapeutic Target.

Dennis P.M. Hughes, MD, PhD, Jeannette L. Tracy, BS, Kenneth E. Lee, BS, Pingyu Zhang, PhD, Zeev Estrov, MD, Joya Chandra, PhD

Blood (2005) 106 (11): 860.

https://doi.org/10.1182/blood.V106.11.860.860

Published: 2005

NARROW

Cigarette Smoke or Cigarette Condensate Exposure Enhances Growth of FLT3-ITD AML Models and Alters DNA Methylation and Leukemic Gene Expression

The Impact of Smoking on Survival in Patients (Pts) with Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia (ALL) Treated with the Combination of Intensive Therapy with Tyrosine Kinase Inhibitor (TKI)

Acceleration of AML Progression By Cigarette Smoke Exposure or Condensate Exposure and Associated DNA Methylation Alterations

Trimethylated H3K27, and Di- and Trimethylated H3K4 Proteomic Profiling Distinguishes Acute Lymphoid Leukemia (ALL) from Acute Myeloid Leukemia (AML) and Associates with Overall Survival and Tyrosine Kinase Inhibitor Sensitivity in Adult ALL

Targeting the NRF2/HO-1 Antioxidant Pathway with Consequences for Notch Signaling in FLT3-ITD Positive AML: A Novel Therapeutic Approach

Accelerated Degradation of cFLIP Mediated By Inhibition of Methyltransferases Sensitizes B-Cell Lymphoma Cells to TRAIL-Induced Apoptosis

HDAC and LSD1 Inhibitors Synergize to Induce Cell Death in Acute Leukemia Cells

Small Molecule Inhibitors of HER2 Inhibit Proliferative Signaling and Promote Apoptosis in Ph+ ALL

A Pilot Study Investigating the Relationship Between Diet and Oxidative Stress in Infants Receiving Therapy for Acute Leukemia

Induction of Oxidative Stress and Glutathione Depletion by ABT-737, a Novel Small Molecule Inhibitor of Bcl-2, Contributes to Cytotoxicity in Leukemia Cells.

ERBB Signaling Promotes BCR-Abl Expression and Modulates Multiple Signaling Pathways as Assessed by High-Throughput, Reverse Phase Protein Array.

Fyn Upregulation Is a Novel ROS-Dependent Mechanism Controlling CML Growth, Progression and Imatinib Resistance.

Increased Superoxide Levels, HO-1 and Fyn Protein Expression in Bcr/abl Overexpressing Cells: Implications for Adaptation and Survival in an Oxidatively Challenging Environment.

The Novel, Orally Active Proteasome Inhibitor, NPI-0052, Induces Apoptosis in Leukemia Lymphoma Cell Lines and Patient Specimens.

ERBB Expression in Philadelphia Chromosome-Positive ALL as a Potential Therapeutic Target.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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