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Journal Articles

BRD4 Inhibitors Enhance the Anti-Tumor Activity of Targeted Therapy in Chronic Lymphocytic Leukemia

Suchitra Sundaram, MD, Cory Mavis, MSc, Juan J Gu, PhD, Pallawi Torka, MD, Francisco J. Hernandez-Ilizaliturri, MD

Blood (2020) 136 (Supplement 1): 37.

https://doi.org/10.1182/blood-2020-143237

Published: 2020

Journal Articles

The Adhesion Molecule ICAM-1 in Diffuse Large B-Cell Lymphoma Post-Rituximab Era: Relationship with Prognostic Importance and Rituximab Resistance

Qunling Zhang, MD PhD, Juan J Gu, PhD, Cory Mavis, MSc, Ye Guo, MD, Matthew J. Barth, MD, Francisco J. Hernandez-Ilizaliturri, MD

Blood (2016) 128 (22): 4212.

https://doi.org/10.1182/blood.V128.22.4212.4212

Published: 2016

Journal Articles

JQ1, a c-MYC Inhibitor Targets Hexokinase II and Enhances the Cytotoxic Effects of Chemotherapeutic Agents in Diffuse Large B-Cell Lymphoma (DLBCL)

Juan J Gu, PhD, Matthew J. Barth, MD, Qunling Zhang, MD PhD, Cory Mavis, MSc, Francisco J. Hernandez-Ilizaliturri, MD

Blood (2016) 128 (22): 5378.

https://doi.org/10.1182/blood.V128.22.5378.5378

Published: 2016

Journal Articles

Itraconazole, an Oral Antifungal Drug, Inhibits Tumor Growth and Enhances Therapeutic Agent Activity in Double Hit Lymphoma

Juan J Gu, PhD, Lianjuan Yang, MD, Benjamin Jarmusz, Daniel Cress, Cory Mavis, MSc, Matthew J. Barth, MD, Francisco J. Hernandez-Ilizaliturri, MD

Blood (2016) 128 (22): 5380.

https://doi.org/10.1182/blood.V128.22.5380.5380

Published: 2016

Journal Articles

Targeting BET Bromodomains in Pre-Clinical Models of Burkitt Lymphoma

Thomas Ippolito, MS, Juan J Gu, PhD, Gregory Tang, Cory Mavis, MSc, Rodney R. Miles, MD PhD, Francisco J. Hernandez-Ilizaliturri, MD, Matthew J. Barth, MD

Blood (2016) 128 (22): 5381.

https://doi.org/10.1182/blood.V128.22.5381.5381

Published: 2016

Journal Articles

Omipalisib (GSK458), a Novel Pan-PI3K/mTOR Inhibitor, Exhibits In Vitro Anti-Lymphoma Activity in Chemotherapy-Sensitive and -Resistant Models of Burkitt Lymphoma

Thomas Ippolito, MS, Greg Tang, Cory Mavis, MSc, Juan J Gu, PhD, Francisco J. Hernandez-Ilizaliturri, MD, Matthew J. Barth, MD

Blood (2016) 128 (22): 5376.

https://doi.org/10.1182/blood.V128.22.5376.5376

Published: 2016

Journal Articles

The XIAP Inhibitor BMT-062789 Displays Anti-Tumor Activity in Cell Line Models of De Novo and Rituximab Relapse/Refractory Lymphoma

Kyle L. Runckel, BS, Cory Mavis, Master, Juan J Gu, PhD, Francisco J. Hernandez-Ilizaliturri, MD

Blood (2016) 128 (22): 5375.

https://doi.org/10.1182/blood.V128.22.5375.5375

Published: 2016

Journal Articles

Itraconazole, an Oral Antifungal Drug, Is Active in Chemotherapy Resistant B-Cell Non-Hodgkin Lymphoma and Enhances the Anti-Tumor Activity of Chemotherapy Agents

Juan J Gu, PhD, Lianjuan Yang, MD, Cory Mavis, MSc, Matthew J. Barth, MD, Francisco J. Hernandez-Ilizaliturri, MD

Blood (2016) 128 (22): 5138.

https://doi.org/10.1182/blood.V128.22.5138.5138

Published: 2016

Journal Articles

Pre-Clinical Investigation of Targeted Therapies for Double Hit Diffuse Large B-Cell Lymphoma (DH-DLBCL)

Priyank P. Patel, MD, Alison Zeccola, Vishala T. Neppalli, MD, Juan J Gu, PhD, Cory Mavis, MSc, Sheila Sait, PhD, Francisco J. Hernandez-Ilizaliturri, MD

Blood (2015) 126 (23): 5122.

https://doi.org/10.1182/blood.V126.23.5122.5122

Published: 2015

Journal Articles

Fc Gamma Rll (CD32b) Expression Affects Anti-CD20 Monoclonal Antibody Cellular Responses and Is Down Regulated in Rituximab Resistant Pre-Clinical Models

Cory Mavis, MSc, Kayle Stewart, Juan J Gu, PhD, Paul K. Wallace, MS, PhD, Francisco J. Hernandez-Ilizaliturri, MD

Blood (2015) 126 (23): 5127.

https://doi.org/10.1182/blood.V126.23.5127.5127

Published: 2015

Journal Articles

Palbociclib (PD-0332991), a Potent Selective CDK4/6 Inhibitor, Overcomes Therapy-Resistant and Sensitizes Diffuse Large B-Cell Lymphoma Pre-Clinical Models to Chemo-Reagents

Juan J Gu, PhD, Qunling Zhang, MD PhD, Cory Mavis, MSc, Myron S. Czuczman, MD, Francisco J. Hernandez-Ilizaliturri, MD

Blood (2015) 126 (23): 3997.

https://doi.org/10.1182/blood.V126.23.3997.3997

Published: 2015

Journal Articles

Dual Inhibition of PKC Delta By Carfilzomib (CFZ) and Ibrutinib Results in Synergistic Activity in Rituximab-Chemotherapy Sensitive and Resistant Lymphoma Pre-Clinical Models and in Primary Tumor Cells Isolated from B-Cell Lymphoma Patients

Qunling Zhang, MD PhD, Juan J Gu, PhD, Ye Guo, MD, Jacob Klos, Cory Mavis, MSc, Myron S. Czuczman, MD, Francisco J. Hernandez-Ilizaliturri, MD

Blood (2015) 126 (23): 4006.

https://doi.org/10.1182/blood.V126.23.4006.4006

Published: 2015

Journal Articles

Metformin Induces p53-Dependent Mitochondrial Stress in Therapy-Sensitive and -Resistant Lymphoma Pre-Clinical Model and Primary Patients Sample with B-Cell Non-Hodgkin Lymphoma (NHL)

Juan J Gu, PhD, Qunling Zhang, MD PhD, Cory Mavis, MSc, Myron S. Czuczman, MD, Francisco J. Hernandez-Ilizaliturri, MD

Blood (2015) 126 (23): 4008.

https://doi.org/10.1182/blood.V126.23.4008.4008

Published: 2015

Journal Articles

JQ1, a Potent c-MYC Inhibitor Overcomes Rituximab-Chemotherapy Resistance in Lymphoma Pre-Clinical Models

Juan J Gu, PhD, Qunling Zhang, MD PhD, Cory Mavis, MSc, Myron S. Czuczman, MD, Francisco J. Hernandez-Ilizaliturri, MD

Blood (2015) 126 (23): 2761.

https://doi.org/10.1182/blood.V126.23.2761.2761

Published: 2015

Journal Articles

Targeting the X-Linked Inhibitor of Apoptosis Protein (XIAP) Can Promote Tumor Cell Death, and Increase the Cytotoxic Effects of Chemotherapy Agents in in Vitro and In Vivo Models of Rituximab-Resistant Lymphoma

Kyle L. Runckel, BS, Cory Mavis, MSc, Joseph Skitzki, Juan J Gu, PhD, Francisco J. Hernandez-Ilizaliturri, MD, Myron S. Czuczman, MD

Blood (2015) 126 (23): 590.

https://doi.org/10.1182/blood.V126.23.590.590

Published: 2015

Journal Articles

Elevated High Sensitivity Troponin T (HsTnT) during Front-Line Therapy with Cyclophosphamide, Doxorubicin, Vincristine and Prednisone +/- Rituximab (CHOP+/-R) or Cyclophosphamide, Epirubicin, Vincristine and Prednisone +/- Rituximab (CEpOP+/-R) Correlates with a Decline in Left Ventricular Ejection Fraction (LVEF) in Patients with Aggressive B-Cell Lymphoma: Results from a Randomized Prospective Clinical Trial NCT00854568

Kai Xue, MD, Juan J Gu, PhD, Qunling Zhang, MD, Xiaojian Liu, MD, Jiachen Wang, Jianfeng Luo, Francisco J. Hernandez-Ilizaliturri, MD, Stanley F. Fernandez, MD, Myron S. Czuczman, MD, Junning Cao, MD Associate Professor, Xiaonan Hong, MD, Ye Guo, MD

Blood (2014) 124 (21): 3041.

https://doi.org/10.1182/blood.V124.21.3041.3041

Published: 2014

Journal Articles

Up-Regulation of Hexokinase II (HK) Alters the Glucose Metabolism and Disrupts the Mitochondrial Potential in Aggressive B-Cell Lymphoma Contributing to Rituximab-Chemotherapy Resistance and Is a Clinically Relevant Target for Future Therapeutic Development

Juan J Gu, PhD, Anil Singh, MD, Cory Mavis, MSc, Vivek Yanamadala, Kai Xue, MD, Michael Grau, Peter Lenz, Georg Lenz, Myron S. Czuczman, MD, Francisco Hernandez, MD

Blood (2014) 124 (21): 1767.

https://doi.org/10.1182/blood.V124.21.1767.1767

Published: 2014

Journal Articles

Metformin Affects the Proliferation Cell Nuclear Antigen (PCNA) and p21 Protein Interaction Resulting in Direct Anti-Tumor Activity and Enhances the Cytotoxic/Biological Effects of Chemotherapy Agents or Rituximab in Lymphoma in Vitro and in Vivo Pre-Clinical Models

Juan J Gu, PhD, Vivek Yanamadala, Anil Singh, MD, Cory Mavis, MSc, Myron S. Czuczman, MD, Francisco Hernandez, MD

Blood (2014) 124 (21): 1781.

https://doi.org/10.1182/blood.V124.21.1781.1781

Published: 2014

NARROW

BRD4 Inhibitors Enhance the Anti-Tumor Activity of Targeted Therapy in Chronic Lymphocytic Leukemia

The Adhesion Molecule ICAM-1 in Diffuse Large B-Cell Lymphoma Post-Rituximab Era: Relationship with Prognostic Importance and Rituximab Resistance

JQ1, a c-MYC Inhibitor Targets Hexokinase II and Enhances the Cytotoxic Effects of Chemotherapeutic Agents in Diffuse Large B-Cell Lymphoma (DLBCL)

Itraconazole, an Oral Antifungal Drug, Inhibits Tumor Growth and Enhances Therapeutic Agent Activity in Double Hit Lymphoma

Targeting BET Bromodomains in Pre-Clinical Models of Burkitt Lymphoma

Omipalisib (GSK458), a Novel Pan-PI3K/mTOR Inhibitor, Exhibits In Vitro Anti-Lymphoma Activity in Chemotherapy-Sensitive and -Resistant Models of Burkitt Lymphoma

The XIAP Inhibitor BMT-062789 Displays Anti-Tumor Activity in Cell Line Models of De Novo and Rituximab Relapse/Refractory Lymphoma

Itraconazole, an Oral Antifungal Drug, Is Active in Chemotherapy Resistant B-Cell Non-Hodgkin Lymphoma and Enhances the Anti-Tumor Activity of Chemotherapy Agents

Pre-Clinical Investigation of Targeted Therapies for Double Hit Diffuse Large B-Cell Lymphoma (DH-DLBCL)

Fc Gamma Rll (CD32b) Expression Affects Anti-CD20 Monoclonal Antibody Cellular Responses and Is Down Regulated in Rituximab Resistant Pre-Clinical Models

Palbociclib (PD-0332991), a Potent Selective CDK4/6 Inhibitor, Overcomes Therapy-Resistant and Sensitizes Diffuse Large B-Cell Lymphoma Pre-Clinical Models to Chemo-Reagents

Dual Inhibition of PKC Delta By Carfilzomib (CFZ) and Ibrutinib Results in Synergistic Activity in Rituximab-Chemotherapy Sensitive and Resistant Lymphoma Pre-Clinical Models and in Primary Tumor Cells Isolated from B-Cell Lymphoma Patients

Metformin Induces p53-Dependent Mitochondrial Stress in Therapy-Sensitive and -Resistant Lymphoma Pre-Clinical Model and Primary Patients Sample with B-Cell Non-Hodgkin Lymphoma (NHL)

JQ1, a Potent c-MYC Inhibitor Overcomes Rituximab-Chemotherapy Resistance in Lymphoma Pre-Clinical Models

Targeting the X-Linked Inhibitor of Apoptosis Protein (XIAP) Can Promote Tumor Cell Death, and Increase the Cytotoxic Effects of Chemotherapy Agents in in Vitro and In Vivo Models of Rituximab-Resistant Lymphoma

Up-Regulation of Hexokinase II (HK) Alters the Glucose Metabolism and Disrupts the Mitochondrial Potential in Aggressive B-Cell Lymphoma Contributing to Rituximab-Chemotherapy Resistance and Is a Clinically Relevant Target for Future Therapeutic Development

Metformin Affects the Proliferation Cell Nuclear Antigen (PCNA) and p21 Protein Interaction Resulting in Direct Anti-Tumor Activity and Enhances the Cytotoxic/Biological Effects of Chemotherapy Agents or Rituximab in Lymphoma in Vitro and in Vivo Pre-Clinical Models

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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