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Judith M. Runnels, PhD
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Journal Articles

Citron Rho Interacting Kinase (CRIK) Regulates Survival in IL-6 Dependent Multiple Myeloma Cells.

Hai T. Ngo, Alexey A. Leontovich, PhD, Aldo M. Roccaro, MD, PhD, Abdel Kareem Azab, Bpharm, PhD, Judith M. Runnels, PhD, Feda Azab, BPharm, Antonio Sacco, Phong Quang, Kenneth C. Anderson, MD, Irene M. Ghobrial, M.D.
Journal: Blood
Blood (2009) 114 (22): 1825.
https://doi.org/10.1182/blood.V114.22.1825.1825
Published: 2009
Journal Articles

The Effect of the CXCR4 Inhibitors, AMD3100 and AMD3465, in Multiple Myeloma Cell Homing and Its Interaction with the Bone Marrow Microenvironment.

Judith M. Runnels, PhD, Abdel Kareem Azab, Bpharm, PhD, Costas Pitsillides, PhD, Jonathan Farag, Juwell Wu, Aldo M. Roccaro, MD, PhD, Patricia Maiso, PhD, Charles P. Lin, PhD, Irene M. Ghobrial, M.D.
Journal: Blood
Blood (2009) 114 (22): 1826.
https://doi.org/10.1182/blood.V114.22.1826.1826
Published: 2009
Journal Articles

MicroRNA Changes Occur in Multiple Myeloma Cells in the Context of Bone Marrow Milieu.

Roccaro M. Roccaro, MD, PhD, Antonio Sacco, Abdel Kareem Azab, BPharm, PhD, Feda Azab, BPharm, Hai Ngo, Molly R Melhem, Phong Quong, Judith M. Runnels, PhD, Kenneth C. Anderson, MD, Irene Ghobrial, M.D.
Journal: Blood
Blood (2009) 114 (22): 1785.
https://doi.org/10.1182/blood.V114.22.1785.1785
Published: 2009
Journal Articles

Role of Selectins in the Pathogenesis of Multiple Myeloma.

Abdel Kareem Azab, Bpharm, PhD, Phong Quang, Feda Azab, BPharm, Costas M Pitsillides, John T Patton, Theodore Smith, Arun Sarkar, Judith M. Runnels, PhD, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Hai T. Ngo, Molly R Melhem, Patricia Maiso, PhD, Kenneth C. Anderson, MD, Charles P. Lin, PhD, John L. Magnani, Irene M. Ghobrial, M.D.
Journal: Blood
Blood (2009) 114 (22): 951.
https://doi.org/10.1182/blood.V114.22.951.951
Published: 2009
Journal Articles

Eph-B2 Receptor Tyrosine Kinase Is Overexpressed in Waldenstrom's Macroglubulinemia and Plays a Major Role in Its Interaction with the Bone Marrow Microenvironment.

Abdel Kareem Azab, Bpharm, PhD, Feda Azab, BPharm, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Phong Quang, Hai T. Ngo, Molly R Melhem, Judith M. Runnels, PhD, Patricia Maiso, PhD, Irene M. Ghobrial, M.D.
Journal: Blood
Blood (2009) 114 (22): 2935.
https://doi.org/10.1182/blood.V114.22.2935.2935
Published: 2009
Journal Articles

RAD001 Exerts Anti-Tumor Activity in Waldenstrom Macroglobulinemia.

Steven Vesole, Xiaoying Jia, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Hai T. Ngo, Feda Azab, BPharm, Abdel Kareem Azab, BPharm, PhD, Molly R Melhem, Judith M. Runnels, PhD, Phong Quang, Kenneth C. Anderson, MD, Irene M. Ghobrial, M.D.
Journal: Blood
Blood (2009) 114 (22): 3732.
https://doi.org/10.1182/blood.V114.22.3732.3732
Published: 2009
Journal Articles

The Role of FGFR in the Progression of Waldenstrom's Macroglubulinemia and the Effect of Its Inhibition by TKI-258.

Feda Azab, BPharm, Abdel Kareem Azab, Bpharm, PhD, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Phong Quang, Hai T Ngo, Molly R Melhem, Judith M. Runnels, PhD, Patricia Maiso, PhD, Irene M Ghobrial, M.D.
Journal: Blood
Blood (2009) 114 (22): 3737.
https://doi.org/10.1182/blood.V114.22.3737.3737
Published: 2009
Journal Articles

Selective Inhibition of the Chymotrypsin-Like Activity of the Immunoproteasome and Constitutive Proteasome Represents a Valid Anti-Tumor Strategy in Waldenstrom Macroglobulinemia.

Aldo M. Roccaro, MD, PhD, Antonio Sacco, Monette Aujay, Hai Ngo, Feda Azab, BPharm, Abdel Kareem Azab, PhD, BPharm, Molly Melhem, Judith M. Runnels, PhD, Phong Quang, Susan Demo, PhD, Irene Ghobrial, M.D.
Journal: Blood
Blood (2009) 114 (22): 4911.
https://doi.org/10.1182/blood.V114.22.4911.4911
Published: 2009
Journal Articles

Carfilzomib Exerts Anti-Neoplastic Activity in Waldenstrom Macroglobulinemia.

Antonio Sacco, Aldo M. Roccaro, MD, PhD, Monette Aujay, PhD, Hai Ngo, Feda Azab, BPharm, Abdel Kareem Azab, Bpharm, PhD, Molly R Melhem, Judith M. Runnels, PhD, Phong Quang, Susan Demo, PhD, Irene Ghobrial, M.D.
Journal: Blood
Blood (2009) 114 (22): 4916.
https://doi.org/10.1182/blood.V114.22.4916.4916
Published: 2009
Journal Articles

Role of Hypoxia in the Progression and Dissemination of Multiple Myeloma.

Abdel Kareem Azab, Bpharm, PhD, Phong Quang, Feda Azab, BPharm, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Judith M. Runnels, PhD, Hai T. Ngo, Molly R Melhem, Patricia Maiso, PhD, Kenneth C. Anderson, MD, Charles P. Lin, PhD, Irene M. Ghobrial, M.D.
Journal: Blood
Blood (2009) 114 (22): 421.
https://doi.org/10.1182/blood.V114.22.421.421
Published: 2009
Journal Articles

Primary Waldesntrom Macroglobulinemia Cells Harbor Constitutive Activation of Akt, mTOR, Rictor and Raptor: Rational for Testing a Dual Inhibitor of the PI3K/Akt and mTOR Pathways in This Disease.

Aldo M. Roccaro, MD, PhD, Antonio Sacco, Emanuel N. Husu, Costas M Pitsillides, PhD, Steven Vesole, Abdel Kareem Azab, BPharm, PhD, Feda Azab, BPharm, Molly Melhem, Hai Ngo, Phong Quang, Patricia Maiso, PhD, Judith M. Runnels, PhD, Charles P. Lin, PhD, Kenneth C. Anderson, MD, Irene Ghobrial, M.D.
Journal: Blood
Blood (2009) 114 (22): 3843.
https://doi.org/10.1182/blood.V114.22.3843.3843
Published: 2009
Journal Articles

A Novel Real-Time In Vivo Homing Model of Multiple Myeloma.

Judith M. Runnels, PhD, Costas Pitsillides, PhD, Joel A. Spencer, Joji Fujisaki, PhD, Hai Ngo, Evdoxia Hatjiharissi, MD, Xavier Leleu, MD, Anne-Sophie Moreau, MD, Xiaoying Jia, Teru Hideshima, MD, Nikhil Munshi, MD, Kenneth C. Anderson, PhD, Charles P. Lin, PhD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2006) 108 (11): 242.
https://doi.org/10.1182/blood.V108.11.242.242
Published: 2006