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Journal Articles

Sialylated Glycans Regulate MUC13 and the Proto-Oncogenes Pim-1 and Myc to Control Hematopoietic Stem and Progenitor Cell Numbers

Leonardo Rivadeneyra, PhD, Melissa M. Lee-Sundlov, PhD, Simon Glabere, Heather Ashwood, Robert Burns, PhD, Karin M. Hoffmeister, MD

Blood (2020) 136 (Supplement 1): 8.

https://doi.org/10.1182/blood-2020-143365

Published: 2020

Journal Articles

Plasmacytoid Dendritic Cells Surveil Megakaryocyte Sialic Acid to Regulate Thrombopoiesis

Melissa M. Lee-Sundlov, PhD, Robert Burns, PhD, Renata Grozovsky, PhD, Silvia Giannini, PhD, Leonardo Rivadeneyra, PhD, Yongwei Zheng, PhD, Simon Glabere, Walter H. Kahr, MDPhDFRCPC, Reza Abdi, Demin Wang, PhD, Karin M. Hoffmeister, MD

Blood (2020) 136 (Supplement 1): 12–13.

https://doi.org/10.1182/blood-2020-142737

Published: 2020

Journal Articles

Endocytosis of the Thrombopoietin Receptor Mpl Regulates Both Megakaryocyte and Erythroid Maturation in Mice

Nathan Eaton, BS, Melissa M. Lee-Sundlov, PhD, Theresa A. Dlugi, PhD, Jon Wieser, BS, Haley E. Ramsey, PhDMSc, Martha Sola-Visner, MD, Karin M. Hoffmeister, MD, Hervé Falet, PhD

Blood (2019) 134 (Supplement_1): 2477.

https://doi.org/10.1182/blood-2019-126820

Published: 2019

Journal Articles

Desialylation and Apoptosis Crosstalk to Modulate Platelet Clearance

Renata Grozovsky, PhD, Cameron Fraser, BS, Karin M. Hoffmeister, MD, Kristopher Sarosiek, PhD, Silvia Giannini, PhD

Blood (2019) 134 (Supplement_1): 1055.

https://doi.org/10.1182/blood-2019-122184

Published: 2019

Journal Articles

M6PR-Specific Targeting of Lysosomal Heparanase Regulates Platelet Hemostatic Function in Mice

Nathan Eaton, BS, Caleb Drew, BS, Theresa A. Dlugi, PhD, Karin M. Hoffmeister, MD, Hervé Falet, PhD

Blood (2019) 134 (Supplement_1): 1059.

https://doi.org/10.1182/blood-2019-129075

Published: 2019

Journal Articles

Novel Glycan Dependent Platelet Clearance Mechanisms

Karin M. Hoffmeister, MD

Blood (2017) 130 (Supplement 1): SCI-31.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-31.SCI-31

Published: 2017

Journal Articles

In Non-Selected Patients Treated for Influenza, Oseltamivir, a Glycosialidase Inhibitor, Demonstrates Improvement in Platelet Counts Compared to Time of Dosing, but Not over Baseline Levels

Sabina I. Cashin, BS, Melissa M. Lee-Sundlov, PhD, Karin M. Hoffmeister, MD, Laura C. Michaelis, MD

Blood (2017) 130 (Supplement 1): 3626.

https://doi.org/10.1182/blood.V130.Suppl_1.3626.3626

Published: 2017

Journal Articles

β1,4-Galactosyltransferase 1 Is a Key Regulator of Thrombopoiesis

Silvia Giannini, PhD, Melissa M. Lee-Sundlov, PhD, Max Adelman, Antonija Jurak Begonja, PhD, Joseph T. Lau, PhD, Herve Falet, PhD, Karin M. Hoffmeister, MD

Blood (2017) 130 (Supplement 1): 1018.

https://doi.org/10.1182/blood.V130.Suppl_1.1018.1018

Published: 2017

Journal Articles

Endocytosis of the Thrombopoietin Receptor Mpl Regulates Both Megakaryocyte and Erythroid Progenitors and Is Critical for Myelofibrosis Development

Melissa M Lee-Sundlov, PhD, Haley E Ramsey, PhD MSc, Robert J Dickey, Martha Sola-Visner, MD, Karin M Hoffmeister, MD, Herve Falet, PhD

Blood (2016) 128 (22): 3714.

https://doi.org/10.1182/blood.V128.22.3714.3714

Published: 2016

Journal Articles

Effects of Platelet Circulatory Age on Platelet Function

Moritz Stolla, MD, Renata Grozovsky, PhD, Melissa M Lee-Sundlov, PhD, Herve Falet, PhD, Karin M. Hoffmeister, MD

Blood (2016) 128 (22): 413.

https://doi.org/10.1182/blood.V128.22.413.413

Published: 2016

Journal Articles

Bone Marrow Macrophage Galectin-3 Regulates Platelet Production through Recognition of O-Glycans on Megakaryocytes

Melissa M Lee-Sundlov, PhD, Renata Grozovsky, PhD, Silvia Giannini, PhD, Martina McGrath, MD, Haley E Ramsey, PhD MSc, Martha Sola-Visner, MD, Karin M. Hoffmeister, MD

Blood (2016) 128 (22): 409.

https://doi.org/10.1182/blood.V128.22.409.409

Published: 2016

Journal Articles

Recognition of Megakaryocyte-Specific T-Antigen By Macrophages Negatively Regulates Platelet Production in Bone Marrow

Melissa M. Lee-Sundlov, PhD, Renata Grozovsky, PhD, Silvia Giannini, PhD, Martina McGrath, MD, Haley Elizabeth Ramsey, PhD MSc, Reza Abdi, MD, Martha Sola-Visner, MD, Karin M. Hoffmeister, MD

Blood (2015) 126 (23): 420.

https://doi.org/10.1182/blood.V126.23.420.420

Published: 2015

Journal Articles

The Ashwell-Morell Receptor Regulates Hepatic Thrombopoietin Production Via JAK2-STAT3 Signaling in Vivo and in Vitro

Renata Grozovsky, PhD, Antonija Jurak Begonja, John H. Hartwig, Prof, Herve Falet, PhD, Karin M Hoffmeister, MD

Blood (2014) 124 (21): 2.

https://doi.org/10.1182/blood.V124.21.2.2

Published: 2014

Journal Articles

Dynamin 2-Dependent Endocytosis Regulates Megakaryopoiesis

Markus Bender, Silvia Giannini, Terese Jönsson, Renata Grozovsky, PhD, Hilary Christensen, Fred G Pluthero, Walter H Kahr, Karin M Hoffmeister, MD, Hervé Falet, PhD

Blood (2014) 124 (21): 339.

https://doi.org/10.1182/blood.V124.21.339.339

Published: 2014

Journal Articles

T-Antigen Expression Causes Macrothrombocytopenia and Extensive Hemophagocytosis in Mice Lacking the Sialyltransferase ST3Gal-I Specifically in Megakaryocytes

Renata Grozovsky, PhD, Silvia Giannini, Haley Ramsey, PhD, Martha Sola-Visner, MD, Karin M Hoffmeister, MD

Blood (2014) 124 (21): 94.

https://doi.org/10.1182/blood.V124.21.94.94

Published: 2014

Journal Articles

Platelets Regulate Thrombopoietin Production: The Missing Link

Karin M Hoffmeister, MD, Hervé Falet, PhD, Renata Grozovsky, PhD

Blood (2014) 124 (21): SCI-52.

https://doi.org/10.1182/blood.V124.21.SCI-52.SCI-52

Published: 2014

Journal Articles

Posttranslational Modification in Megakaryocytes Regulates β1 Integrin Expression, Migration and Platelet Production in Vivo

Silvia Giannini, Max Adelman, Antonija Jurak Begonja, Karin M Hoffmeister, MD

Blood (2014) 124 (21): 1435.

https://doi.org/10.1182/blood.V124.21.1435.1435

Published: 2014

Journal Articles

Platelet Desialylation: A Novel Mechanism of Fc-Independent Platelet Clearance and a Potential Diagnostic Biomarker and Therapeutic Target in immune Thrombocytopenia

June Li, MSc, Dianne Evertdina van der Wal, PhD, Guangheng Zhu, MD, Miao Xu, MSc, MD, Issaka Yougbare, PhD, Li Ma, PhD, Brian Vadasz, BSc, Renata Grozovsky, PhD, Min Ruan, MD, Lingyan Zhu, MD, Qingshu Zeng, MD, Lili Tao, MD, Zhi-min Zhai, MD, Jun Peng, MD, Ming Hou, MD, Valery Leytin, PhD, John J. Freedman, MD, Karin M Hoffmeister, MD, Heyu Ni, MD PhD

Blood (2014) 124 (21): 467.

https://doi.org/10.1182/blood.V124.21.467.467

Published: 2014

Journal Articles

Sialic Acid Loss Regulates Platelet Survival and Integrity

Renata Grozovsky, PhD, Gerard Jansen, MD, PhD, MSC, Karin M. Hoffmeister, MD

Blood (2013) 122 (21): 3504.

https://doi.org/10.1182/blood.V122.21.3504.3504

Published: 2013

Journal Articles

Aberrant Type-2-Lactosaminoglycan Synthesis Severely Impairs Thrombopoiesis

Silvia Giannini, Antonija Jurak Begonja, PhD, Max Adelmann, Karin M. Hoffmeister, MD

Blood (2013) 122 (21): 2320.

https://doi.org/10.1182/blood.V122.21.2320.2320

Published: 2013

NARROW

Sialylated Glycans Regulate MUC13 and the Proto-Oncogenes Pim-1 and Myc to Control Hematopoietic Stem and Progenitor Cell Numbers

Plasmacytoid Dendritic Cells Surveil Megakaryocyte Sialic Acid to Regulate Thrombopoiesis

Endocytosis of the Thrombopoietin Receptor Mpl Regulates Both Megakaryocyte and Erythroid Maturation in Mice

Desialylation and Apoptosis Crosstalk to Modulate Platelet Clearance

M6PR-Specific Targeting of Lysosomal Heparanase Regulates Platelet Hemostatic Function in Mice

Novel Glycan Dependent Platelet Clearance Mechanisms

In Non-Selected Patients Treated for Influenza, Oseltamivir, a Glycosialidase Inhibitor, Demonstrates Improvement in Platelet Counts Compared to Time of Dosing, but Not over Baseline Levels

β1,4-Galactosyltransferase 1 Is a Key Regulator of Thrombopoiesis

Endocytosis of the Thrombopoietin Receptor Mpl Regulates Both Megakaryocyte and Erythroid Progenitors and Is Critical for Myelofibrosis Development

Effects of Platelet Circulatory Age on Platelet Function

Bone Marrow Macrophage Galectin-3 Regulates Platelet Production through Recognition of O-Glycans on Megakaryocytes

Recognition of Megakaryocyte-Specific T-Antigen By Macrophages Negatively Regulates Platelet Production in Bone Marrow

The Ashwell-Morell Receptor Regulates Hepatic Thrombopoietin Production Via JAK2-STAT3 Signaling in Vivo and in Vitro

Dynamin 2-Dependent Endocytosis Regulates Megakaryopoiesis

T-Antigen Expression Causes Macrothrombocytopenia and Extensive Hemophagocytosis in Mice Lacking the Sialyltransferase ST3Gal-I Specifically in Megakaryocytes

Platelets Regulate Thrombopoietin Production: The Missing Link

Posttranslational Modification in Megakaryocytes Regulates β1 Integrin Expression, Migration and Platelet Production in Vivo

Platelet Desialylation: A Novel Mechanism of Fc-Independent Platelet Clearance and a Potential Diagnostic Biomarker and Therapeutic Target in immune Thrombocytopenia

Sialic Acid Loss Regulates Platelet Survival and Integrity

Aberrant Type-2-Lactosaminoglycan Synthesis Severely Impairs Thrombopoiesis

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American Society of Hematology

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American Society of Hematology

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