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Journal Articles

Oral Administration of FT-4202, an Allosteric Activator of Pyruvate Kinase-R, Has Potent Anti-Sickling Effects in a Sickle Cell Anemia (SCA) Mouse Model, Resulting in Improved RBC Survival and Hemoglobin Levels

Archana Shrestha, Mengna Chi, PhD, Kimberly Wagner, Adam Drake, Keertik Fulzele, PhD, Sylvie Guichard, Punam Malik, MD

Blood (2020) 136 (Supplement 1): 21–22.

https://doi.org/10.1182/blood-2020-140875

Published: 2020

Journal Articles

Ex-Vivo FT-4202 Treatment Improves Hemoglobin Oxygen Affinity and Membrane Health in Red Blood Cells of Patients with Hemoglobin SS and Hemoglobin SC Disease Irrespective of Prior Hydroxyurea Use

Diamantis G. Konstantinidis, PhD BSc, Rose Fessler, Katie Giger Seu, PhD, Bhargav Patel, Jennifer B Korpik, Keertik Fulzele, PhD, Sylvie Guichard, Theodosia A. Kalfa, MD PhD

Blood (2020) 136 (Supplement 1): 23–24.

https://doi.org/10.1182/blood-2020-139714

Published: 2020

Journal Articles

A Novel in-Vivo Model to Examine Homing of Multiple Myeloma Cells in Postnatal, Inducible, and Reversible Loss of Mature Osteoblasts

Cristina Panaroni, PhD, Keertik Fulzele, PhD, Tomoaki Mori, Chukwuamaka Onyewadume, Noopur S. Raje, MD

Blood (2020) 136 (Supplement 1): 50.

https://doi.org/10.1182/blood-2020-143182

Published: 2020

Journal Articles

Multiple Myeloma Cells Induce Lipolysis in Adipocytes and Uptake Fatty Acids through Fatty Acid Transporter Proteins

Cristina Panaroni, PhD, Keertik Fulzele, PhD, Tomoaki Mori, Chukwuamaka Onyewadume, Noopur S. Raje, MD

Blood (2020) 136 (Supplement 1): 41–42.

https://doi.org/10.1182/blood-2020-142625

Published: 2020

Journal Articles

Osteoclast-Induced Immunosuppression Occurs through Dysregulation of Immune Checkpoint Axes in Multiple Myeloma

Kenta Mukaihara, MD PhD, Mattia D'Agostino, MD, Cristina Panaroni, PhD, Keertik Fulzele, PhD, Tomoaki Mori, MD PhD, Ka Tat Siu, PhD, Shrikanta Chattopadhyay, MBBS, Noopur Raje, MD

Blood (2019) 134 (Supplement_1): 4382.

https://doi.org/10.1182/blood-2019-130462

Published: 2019

Journal Articles

Mature Osteoblasts Promote Multiple Myeloma Survival through Cell-Cell Contact and Immune Modulation Mechanisms

Keertik Fulzele, PhD, Cristina Panaroni, PhD, Kenta Mukaihara, MD PhD, Tomoaki Mori, MD PhD, Shrikanta Chattopadhyay, MBBS, Noopur S. Raje, MD

Blood (2019) 134 (Supplement_1): 1802.

https://doi.org/10.1182/blood-2019-131213

Published: 2019

Journal Articles

Polyunsaturated Fatty Acid (PUFA) Signaling Induces Ferroptosis-Mediated Cell-Death in Multiple Myeloma

Cristina Panaroni, PhD, Keertik Fulzele, PhD, Rosemary Soucy, Cherrie Huang, Kenta Mukaihara, MD PhD, Shrikanta Chattopadhyay, MBBS, Noopur S. Raje, MD

Blood (2019) 134 (Supplement_1): 3108.

https://doi.org/10.1182/blood-2019-131906

Published: 2019

Journal Articles

Mature Osteoblasts Provide a Protective Niche Against Multiple Myeloma Growth and Survival within the Tumor Microenvironment

Keertik Fulzele, PhD, Cristina Panaroni, PhD, Rosemary Soucy, Ka Tat Siu, PhD, Kenta Mukaihara, MD PhD, Noopur Raje, MD

Blood (2018) 132 (Supplement 1): 4476.

https://doi.org/10.1182/blood-2018-99-118377

Published: 2018

Journal Articles

The Pleiotropic Immunosuppressive Role of Osteoclasts in Multiple Myeloma

Kenta Mukaihara, MD PhD, Ka Tat Siu, PhD, Cristina Panaroni, PhD, Keertik Fulzele, PhD, Rosemary Soucy, Cherrie Huang, Shrikanta Chattopadhyay, MBBS, Noopur Raje, MD

Blood (2018) 132 (Supplement 1): 4447.

https://doi.org/10.1182/blood-2018-99-114922

Published: 2018

Journal Articles

Arachidonic Acid Induces Ferroptosis-Mediated Cell-Death in Multiple Myeloma

Cristina Panaroni, PhD, Keertik Fulzele, PhD, Rosemary Soucy, Ka Tat Siu, PhD, Kenta Mukaihara, MD PhD, Cherrie Huang, Shrikanta Chattopadhyay, MBBS, Noopur Raje, MD

Blood (2018) 132 (Supplement 1): 4498.

https://doi.org/10.1182/blood-2018-99-118482

Published: 2018

Journal Articles

Overcoming MCL1 Resistance in Multiple Myeloma

Ka Tat Siu, PhD, Cherrie Huang, Cristina Panaroni, PhD, Kenta Mukaihara, MD PhD, Keertik Fulzele, PhD, Rosemary Soucy, Justin Cidado, PhD, Lisa Drew, PhD, Shrikanta Chattopadhyay, MBBS, Noopur Raje, MD

Blood (2018) 132 (Supplement 1): 472.

https://doi.org/10.1182/blood-2018-99-116377

Published: 2018

Journal Articles

Role of Sclerostin in Multiple Myeloma Progression

Cristina Panaroni, PhD, Keertik Fulzele, PhD, Ka Tat Siu, PhD, Peter Wang, BS, Noopur Raje, MD

Blood (2017) 130 (Supplement 1): 4341.

https://doi.org/10.1182/blood.V130.Suppl_1.4341.4341

Published: 2017

Journal Articles

Differential Regulation of Myeloid Leukemias by the Bone Marrow Microenvironment

Daniela S. Krause, M.D., Ph.D., Keertik Fulzele, PhD, Andre Catic, MD PhD, Michael Hurley, Sanon Lezeau, Eyal C. Attar, MD, Joy Y. Wu, Herbert Yih-Fuu Lin, MD, PhD, Paola Divieti-Pajevic, MD PhD, Robert Hasserjian, MD, Ernestina Schipani, MD, Richard A. Van Etten, MD PhD, David T. Scadden, MD

Blood (2012) 120 (21): 1245.

https://doi.org/10.1182/blood.V120.21.1245.1245

Published: 2012

Journal Articles

Osteocytes Support Hematopoiesis by Altering the Bone Marrow Microenvironment Through Gsα Signaling

Daniela S. Krause, MD, PhD, Keertik Fulzele, PhD, Kevin Barry, Sutada Lotinun, Roland Baron, Lynda Bonewald, Jian Q Feng, Min Chen, Lee S Weinstein, Mary Bouxsein, David T. Scadden, MD, Paola Divieti-Pajevic, MD PhD

Blood (2011) 118 (21): 219.

https://doi.org/10.1182/blood.V118.21.219.219

Published: 2011

Journal Articles

Parathyroid Hormone-Induced Modulation of the Bone Marrow Microenvironment Reduces Leukemic Stem Cells in Murine Chronic Myelogenous-Leukemia-Like Disease Via a TGFbeta-Dependent Pathway

Daniela S. Krause, MD, PhD, Keertik Fulzele, PhD, Andre Catic, MD PhD, Michael Hurley, Sanon Lezeau, Robert Hasserjian, MD, Joy Wu, MD PhD, Paola Divieti-Pajevic, MD PhD, Richard A. Van Etten, MD PhD, Ernestina Schipani, MD, David T. Scadden, MD

Blood (2011) 118 (21): 1670.

https://doi.org/10.1182/blood.V118.21.1670.1670

Published: 2011

NARROW

Oral Administration of FT-4202, an Allosteric Activator of Pyruvate Kinase-R, Has Potent Anti-Sickling Effects in a Sickle Cell Anemia (SCA) Mouse Model, Resulting in Improved RBC Survival and Hemoglobin Levels

Ex-Vivo FT-4202 Treatment Improves Hemoglobin Oxygen Affinity and Membrane Health in Red Blood Cells of Patients with Hemoglobin SS and Hemoglobin SC Disease Irrespective of Prior Hydroxyurea Use

A Novel in-Vivo Model to Examine Homing of Multiple Myeloma Cells in Postnatal, Inducible, and Reversible Loss of Mature Osteoblasts

Multiple Myeloma Cells Induce Lipolysis in Adipocytes and Uptake Fatty Acids through Fatty Acid Transporter Proteins

Osteoclast-Induced Immunosuppression Occurs through Dysregulation of Immune Checkpoint Axes in Multiple Myeloma

Mature Osteoblasts Promote Multiple Myeloma Survival through Cell-Cell Contact and Immune Modulation Mechanisms

Polyunsaturated Fatty Acid (PUFA) Signaling Induces Ferroptosis-Mediated Cell-Death in Multiple Myeloma

Mature Osteoblasts Provide a Protective Niche Against Multiple Myeloma Growth and Survival within the Tumor Microenvironment

The Pleiotropic Immunosuppressive Role of Osteoclasts in Multiple Myeloma

Arachidonic Acid Induces Ferroptosis-Mediated Cell-Death in Multiple Myeloma

Overcoming MCL1 Resistance in Multiple Myeloma

Role of Sclerostin in Multiple Myeloma Progression

Differential Regulation of Myeloid Leukemias by the Bone Marrow Microenvironment

Osteocytes Support Hematopoiesis by Altering the Bone Marrow Microenvironment Through Gsα Signaling

Parathyroid Hormone-Induced Modulation of the Bone Marrow Microenvironment Reduces Leukemic Stem Cells in Murine Chronic Myelogenous-Leukemia-Like Disease Via a TGFbeta-Dependent Pathway

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American Society of Hematology

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American Society of Hematology

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