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Kenneth C. Anderson, M.D.
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Journal Articles

Bone Marrow Niche Down-Regulates Mir-30 In Multiple Myeloma Cells to Promote Cancer Progression and Cancer Initiation by Targeting BCL9/Wnt Pathway.

Jian-Jun Zhao, M.D., Ph.D., Jianhong Lin, M.D., Zhangbo Chu, M.D., Qi Wang, Ph.D., Kohichi Takada, M.D., Ph.D., Mala Mani, Ph.D., Bryan Ciccarelli, Teru Hideshima, M.D., Ph.D., Tai Yu-Tzu, Ph.D., Jianguo Tao, MD, PhD, Steven P. Treon, MD, PhD, Nikhil C. Munshi, M.D., Kenneth C. Anderson, M.D., Ruben Carrasco, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1569.
https://doi.org/10.1182/blood.V116.21.1569.1569
Published: 2010
Journal Articles

The Interaction of Bortezomib with P-Gp, MRP-1 and BCRP Drug Transporters: Implications for Therapeutic Applications of Bortezomib in Advanced Multiple Myeloma and Other Neoplasias.

Melissa G Ooi, M.D., Robert O'Connor, Ph.D, Jana Jakubikova, Ph.D, Justine Meiller, Diploma, in, Biochemistry, Degre, Steffen Klippel, Ph.D, Jake Delmore, Efstathios Kastritis, M.D, Douglas McMillin, Ph.D, Martin Clynes, Ph.D, Paul Richardson, M.D., Constantine S. Mitsiades, M.D., Ph.D, Peter O'Gorman, M.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2009) 114 (22): 1729.
https://doi.org/10.1182/blood.V114.22.1729.1729
Published: 2009
Journal Articles

Dendritic Cell Tumor Fusion Vaccination in Conjunction with Autologous Transplantation for Multiple Myeloma.

Jacalyn Rosenblatt, MD, Irit Avivi, MD, Baldev Vasir, PhD, Tami Katz, Ph.D, Lynne Uhl, MD, Zekui Wu, MD, Poorvi Somaiya, Heidi Mills, Robin Joyce, MD, James D. Levine, MD, Dimitrios Tzachanis, MD, PhD, Vassiliki Boussiotis, MD, PhD, Brett Glotzbecker, MD, Karen Francoeur, Dilani Dombagoda, Michal Tsumer, Lina Bisharat, Nancy Giallombardo, NP, Katharine Conway, NP, Donna Fitzgerald, PA, Rachal Barhad, Paul Richardson, M.D., Ph.D., Kenneth C. Anderson, M.D., Ph.D., Nikhil C. Munshi, MD, Jacob M. Rowe, MD, Donald Kufe, MD, David Avigan, MD
Journal: Blood
Blood (2009) 114 (22): 783.
https://doi.org/10.1182/blood.V114.22.783.783
Published: 2009
Journal Articles

Combination of Nab -Rapamycin and Perifosine Induces Synergistic Cytotoxicity and Antitumor Activity Via Autophagy and Apoptosis in Multiple Myeloma (MM)

Diana Cirstea, M.D., Teru Hideshima, M.D., Ph.D., Samantha Pozzi, M.D., Sonia Vallet, M.D., Hiroshi Ikeda, M.D., Ph.D., Loredana Santo, M.D., Scott Rodig, M.D., Ph.D., Nileshwari Vaghela, M.B.S, Treeve Currie, Yutaka Okawa, M.D., Ph.D., Gaurav Chhetri, Chirayu G. Patel, Giulia Perrone, M.D., Gullu Gorgun, Ph.D., Elisabetta Calabrese, M.D., Voung Trieu, Neil Desai, Ph.D., Peter Sportelli, Nikhil C. Munshi, M.D., Kenneth C Anderson, M.D., Noopur Raje, M.D.
Journal: Blood
Blood (2008) 112 (11): 3663.
https://doi.org/10.1182/blood.V112.11.3663.3663
Published: 2008
Journal Articles

RGB 286638, a Novel Multi-Targeted Small Molecule Inhibitor, Induces Multiple Myeloma (MM) Cell Death through Abrogation of CDKDependent and Independent Survival Mechanisms

Diana Cirstea, M.D., Teru Hideshima, M.D., Ph.D., Samantha Pozzi, M.D., Sonia Vallet, M.D., Hiroshi Ikeda, M.D., Ph.D., Loredana Santo, M.D., Hannes Loferer, Nileshwari Vaghela, M.B.S., Yutaka Okawa, M.D., Ph.D., Giulia Perrone, M.D., Gullu Gorgun, Ph.D., Elisabetta Calabrese, M.D., Nikhil C. Munshi, MD, Kenneth C. Anderson, M.D., Noopur Raje, M.D.
Journal: Blood
Blood (2008) 112 (11): 2759.
https://doi.org/10.1182/blood.V112.11.2759.2759
Published: 2008
Journal Articles

Treatment Patterns among Patients with Recently-Diagnosed Multiple Myeloma in a National Registry

Carla M. Van Bennekom, M.P.H., Noopur Raje, MD, Kenneth C. Anderson, M.D., Theresa E. Anderson, R.N., Davi d W. Kaufman, ScD
Journal: Blood
Blood (2008) 112 (11): 2374.
https://doi.org/10.1182/blood.V112.11.2374.2374
Published: 2008
Journal Articles

Molecular Profiling of Extramedullary and Medullary Plasmacytomas

Gabriela Motyckova, M.D., Ph.D., Aliyah Rahemtullah, M.D., Nileshwari Vaghela, M.S., Sonia Vallet, M.D., Adam Ackerman, Siddhartha Mukherjee, M.D., Ph.D., Samantha Pozzi, M.D., Loredana Santo, Ph.D., Diana Cirstea, M.D., Christiana Toomey, Ephraim P. Hochberg, M.D., Paola Dal Cin, Ph.D., Scott Rodig, M.D., Ph.D., Teru Hideshima, M.D., Ph.D., Kenneth C Anderson, M.D., Nikhil Munshi, M.D., Noopur Raje, M.D.
Journal: Blood
Blood (2008) 112 (11): 5111.
https://doi.org/10.1182/blood.V112.11.5111.5111
Published: 2008
Journal Articles

Low Levels of Circulating CS1, a Newly Identified Multiple Myeloma (MM) Antigen for a Novel Humanized HuLuc63 Monoclonal Antibody, Is Detected in MM Patient Sera and Correlates with Active Disease.

Yu-Tzu Tai, PhD, Audie G. Rice, Ph.D., Marav Leiba, M.D., Xian-Feng Li, M.S., Peter Burger, B.S., Weihua Song, M.D., Rao Prabhala, Ph.D., Myles Dillon, B.S., Edie Tolan, Ph.D., Xanling Xie, Ph.D., Teru Hideshima, M.D., Ph.D., Noopur Raje, M.D., Paul Richardson, M.D., Nihkil C. Munshi, M.D., Arnon Nagler, M.D., Herve Avet-Loiseau, M.D., Daniel E.H. Afar, Ph.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2007) 110 (11): 1509.
https://doi.org/10.1182/blood.V110.11.1509.1509
Published: 2007
Journal Articles

Activation of B-Cell Maturation Antigen (BCMA) on Human Multiple Myeloma Cells by a Proliferation-Inducing Ligand (APRIL) Promotes Myeloma Cell Function in the Bone Marrow Microenvironment.

Merav Leiba, M.D., Jiangchun Xu, M.D., Ph.D., Weihua Song, M.D., Xian-Feng Li, M.S., Peter Burger, B.S., Jennifer Kordich, M.S., Linda Cassiano, B.A., Klaus Podar, M.D., Ph.D., Dharminder Chauhan, Ph.D., Teru Hideshima, M.D., Ph.D., Nikhil C. Munshi, M.D., Paul Richardson, M.D., Kenneth C. Anderson, M.D., Yu-Tzu Tai, PhD
Journal: Blood
Blood (2007) 110 (11): 1503.
https://doi.org/10.1182/blood.V110.11.1503.1503
Published: 2007
Journal Articles

Combination of Proteasome Inhibitors Bortezomib and NPI-0052 Trigger In Vivo Synergistic Cytotoxicity in Multiple Myeloma.

Dharminder Chauhan, PhD, Ajita Singh, Ph.D, Mohan Brahmandam, M.S, Klaus Podar, Ph.D, Teru Hideshima, M.D., Robert Schlossman, M.D., Paul Richardson, M.D., Nikhil Munshi, M.D., Michael Palladino, Ph.D, Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2007) 110 (11): 2524.
https://doi.org/10.1182/blood.V110.11.2524.2524
Published: 2007
Journal Articles

Acquisition of New In Vivo Genomic Change over Time in Multiple Myeloma.

Yu-Tzu Tai, PhD, Leutz Buon, M.S., Benjamin King, B.S., Cheng Li Cheng Li, Ph.D., Peter Burger Peter Burger, B.S., Xian-Feng Li, M.S., Weihua Song, M.D., Robert Schlossman, M.D., Paul Richardson, M.D., Kenneth C. Anderson, M.D., Nikhil Munshi, M.D.
Journal: Blood
Blood (2007) 110 (11): 2481.
https://doi.org/10.1182/blood.V110.11.2481.2481
Published: 2007
Journal Articles

CS1, a New Surface Target on Multiple Myeloma (MM) Cells, Protects Myeloma Cells from Apoptosis Via Regulation of ERK1/2, AKT and STAT3 Signaling Cascades.

Yu-Tzu Tai, PhD, Giovanni Tonon, M.D., Ph.D., Merav Leiba, M.D., Xian-Feng Li, M.S., Peter Burger, B.S., Weihua Song, M.D., Klaus Podar, M.D., Ph.D., Dharminder Chauhan, Ph.D., Nihkil Munshi, M.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2007) 110 (11): 109.
https://doi.org/10.1182/blood.V110.11.109.109
Published: 2007
Journal Articles

Plasmacytoid Dendritic Cells Induce Growth and Survival of Multiple Myeloma Cells: Therapeutic Application.

Dharminder Chauhan, PhD, Mohan Brahmandam, M.S., Ajita Singh, Ph.D, Giada Bianchi, M.D., Klaus Podar, M.D., Ruben Carrasco, Ph.D, Paul Richardson, M.D., Nikhil Munshi, M.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2007) 110 (11): 3507.
https://doi.org/10.1182/blood.V110.11.3507.3507
Published: 2007
Journal Articles

Genomic Evolution of Multiple Myeloma In Vivo over Time.

Yu-Tzu Tai, PhD, Benjamin King, B.S., Cheng Li, Ph.D., XianFeng Li, M.S., Peter Burger, B.S., Weihua Song, M.D., Masood Shammas, Ph.D., Robert Schlossman, M.D., Paul Richardson, M.D., Kenneth C. Anderson, M.D., Nikhil C. Munshi, M.D.
Journal: Blood
Blood (2006) 108 (11): 3400.
https://doi.org/10.1182/blood.V108.11.3400.3400
Published: 2006
Journal Articles

Nifuroxazide Inhibits STAT3 Function and Shows Potent Anti-Tumor Activity Against Multiple Myeloma.

Erik A. Nelson, PhD, Teru Hideshima, M.D. Ph.D, Laurie Gashin, Sarah R. Walker, B.S., Rebecca A. Lynch, B.S., Dharminder Chauhan, Ph.D., Kenneth C. Anderson, M.D., David A. Frank, M.D.,Ph.D.
Journal: Blood
Blood (2006) 108 (11): 3450.
https://doi.org/10.1182/blood.V108.11.3450.3450
Published: 2006
Journal Articles

The BAFF Inhibitor AMG523 Blocks Adhesion and Survival of Human Multiple Myeloma Cells in the Bone Marrow Microenvironment: Clinical Implication.

Yu-Tzu Tai, PhD, Jiangchun Xu, M.D., Xian-Feng Li, M.S., Iris Breitkreutz, M.D., Klaus Podar, M.D. Ph.D., Teru Hideshima, M.D. Ph.D., Robert Schlossman, M.D., Paul Richardson, M.D., Nikhil C. Munshi, M.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2006) 108 (11): 3452.
https://doi.org/10.1182/blood.V108.11.3452.3452
Published: 2006
Journal Articles

Inhibition of ERK1/2 Activity by the MEK1/2 Inhibitor AZD6244 (ARRY-142886) Induces Human Multiple Myeloma Cell Apoptosis in the Bone Marrow Microenvironment: A New Therapeutic Strategy for MM.

Yu-Tzu Tai, PhD, Xian-Feng Li, M.S., Iris Breitkreutz, M.D., Weihua Song, M.D., Peter Burger, B.S., Matthew Rumizen, Teru Hideshima, M.D. Ph.D., Klaus Podar, M.D. Ph.D., Irene Ghobrial, M.D., Robert Schlossman, M.D., Paul Richardson, M.D., Nikhil C. Munshi, M.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2006) 108 (11): 3460.
https://doi.org/10.1182/blood.V108.11.3460.3460
Published: 2006
Journal Articles

The MEK1/2 Inhibitor AZD6244 (ARRY-142886) Downregulates Constitutive and Adhesion-Induced c- MAF Oncogene Expression and Its Downstream Targets in Human Multiple Myeloma.

Yu-Tzu Tai, PhD, Giovanni Tonon, Ph.D., Xian-Feng Li, M.S., Matthew Rumizen, Weihua Song, M.D., Aileen Morrison, B.S., Peter Burger, B.S., Nikhil C. Munshi, M.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2006) 108 (11): 3463.
https://doi.org/10.1182/blood.V108.11.3463.3463
Published: 2006
Journal Articles

Killing of Drug-Sensitive and Resistant Myeloma Cells and Disruption of Their Bone Marrow Stromal Interaction by HuLuc63, a Novel Humanized Anti-CS1 Monoclonal Antibody.

Yu-Tzu Tai, PhD, Weihua Song, M.D., Xian-Feng Li, M.S., Peter Burger, B.S., Robert Schlossman, M.D., Audie Rice, Ph.D., Anne van Abbema, Ph.D., Paul Richardson, M.D., Nikhil C. Munshi, M.D., Daniel Afar, Ph.D., Kenneth C. Anderson, M.D.
Journal: Blood
Blood (2006) 108 (11): 3470.
https://doi.org/10.1182/blood.V108.11.3470.3470
Published: 2006
Journal Articles

Bcl-2, Mcl-1 and p53 Expression Confer Sensitivity to Bcl-2 Inhibitor ABT-737 in Multiple Myeloma.

Dharminder Chauhan, PhD, Mohan Brahmandam, M.S, Teru Hideshima, Ph.D, Klaus Podar, Ph.D, Nikhil Munshi, M.D, Noopur Raje, M.D, Kenneth C. Anderson, M.D
Journal: Blood
Blood (2006) 108 (11): 3474.
https://doi.org/10.1182/blood.V108.11.3474.3474
Published: 2006