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    Kevin Sprott, PhD
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    Journal Articles

    Sy-1365, a Potent and Selective CDK7 Inhibitor, Exhibits Anti-Tumor Activity in Preclinical Models of Hematologic Malignancies, and Demonstrates Interactions with the BCL-XL/BCL2 Mitochondrial Apoptosis Signaling Pathway in Leukemia

    Graeme Hodgson, PhD, Liv Johannessen, PhD, Nisha Rajagopal, PhD, Shanhu Hu, PhD, David Orlando, PhD, Matthew Eaton, PhD, Michael McKeown, PhD, Jeffrey W. Tyner, PhD, Stephen E Kurtz, PhD, Kevin Sprott, PhD, Christian Fritz, PhD, Emmanuelle Di Tomaso, PhD
    Journal: Blood
    Blood (2017) 130 (Supplement 1): 2651.
    https://doi.org/10.1182/blood.V130.Suppl_1.2651.2651
    Published: 2017
    Journal Articles

    Targeting Transcriptional Dependency in Acute Myeloid Leukemia (AML) with a Covalent Inhibitor of Transcriptional Kinase CDK7

    Yixuan Ren, B.S., Victoria Brown, M.S., Shanhu Hu, PhD, Jeremy Lopez, B.S., Sofija Miljovska, PhD, Darby Schmidt, PhD, Michael Bradley, PhD, Kevin Sprott, PhD, Eric Olson, PhD, Christian C. Fritz, PhD, Yoon Jong Choi, PhD
    Journal: Blood
    Blood (2015) 126 (23): 1354.
    https://doi.org/10.1182/blood.V126.23.1354.1354
    Published: 2015

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