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Journal Articles

LRPAP1 autoantibodies in mantle cell lymphoma are associated with superior outcome

Blood (2021) 137 (23): 3251–3258.

https://doi.org/10.1182/blood.2020008835

Published: 2021

Includes: Supplemental data

Journal Articles

Identification and Characterization of CMV-Specific, HLA-C*07:02 Restricted Antibodies

Moritz Bewarder, MD, Gerhard Held, MD, Lorenz Thurner, MD, Klaus Dieter Preuss, PhD, Gabi Carbon, Birgit Bette, Konstantinos Christofyllakis, MD, Arne Felbel, Dominic Kaddu-Mulindwa, MD, Niels Murawski, MD, Stephan Stilgenbauer, Frank Neumann, PhD

Blood (2019) 134 (Supplement_1): 5616.

https://doi.org/10.1182/blood-2019-126998

Published: 2019

Journal Articles

The B-Cell Receptor Antigen ARS2 Can be Integrated into a BAR-Body Format to Treat Diffuse Large B-Cell Lymphomas in Xenograft Mouse Models

Moritz Bewarder, MD, Christina Körbel, PhD, Matthias W. Laschke, PhD, Michael D. Menger, MD, Maximilian Kiefer, Dominic Kaddu-Mulindwa, MD, Helene Will, Lisa Goerens, Natalie Fadle, Evi Regitz, Stephan Stilgenbauer, Frank Neumann, PhD, Klaus Dieter Preuss, PhD, Michael Pfreundschuh, MD, Lorenz Thurner, MD

Blood (2019) 134 (Supplement_1): 2860.

https://doi.org/10.1182/blood-2019-131434

Published: 2019

Journal Articles

Hyper- N -glycosylated SAMD14 and neurabin-I as driver autoantigens of primary central nervous system lymphoma

Blood (2018) 132 (26): 2744–2753.

https://doi.org/10.1182/blood-2018-03-836932

Published: 2018

Includes: Supplemental data

Journal Articles

Identification of Posttranvslationally Modified Neoantigens As Targets of B Cell Receptors of Burkitt Lymphoma

Lorenz Thurner, MD, Sylvia Hartmann, MD, Theresa Bock, Natalie Fadle, Maria Kemele, Evi Regitz, Moritz Bewarder, MD, Sigrun Smola, Thorsten Pfuhl, Jana Held, Rainer-Maria Bohle, Laurence de Leval, MD, Rabea Wagener, Reiner Siebert, PhD, Martin-Leo Hansmann, Stephan Stilgenbauer, MD PhD, Klaus Dieter Preuss, PhD, Michael Pfreundschuh, MD

Blood (2018) 132 (Supplement 1): 1588.

https://doi.org/10.1182/blood-2018-99-114209

Published: 2018

Journal Articles

BAR-Bodies: B-Cell Receptor Antigens As the Targeting Moiety of Antibodies in Substitution for the Variable Region of Heavy and Light Chains

Moritz Bewarder, MD, Lorenz Thurner, MD, Frank Neumann, PhD, Natalie Fadle, Evi Regitz, Maria Kemele, Helene Will, Lisa Goerens, Konstantinos Christofyllakis, MD, Dominic Kaddu-Mulindwa, MD, Stephan Stilgenbauer, Maximilian Kiefer, Klaus Dieter Preuss, PhD

Blood (2018) 132 (Supplement 1): 2940.

https://doi.org/10.1182/blood-2018-99-115348

Published: 2018

Journal Articles

B-Cell Receptor Antigens As the Targeting Moiety for Bispecific Constructs - a Novel Treatment Approach for B-Cell Lymphomas

Moritz Bewarder, MD, Lorenz Thurner, MD, Klaus Dieter Preuss, PhD, Evi Regitz, Natalie Fadle, Michael Pfreundschuh, MD

Blood (2017) 130 (Supplement 1): 111.

https://doi.org/10.1182/blood.V130.Suppl_1.111.111

Published: 2017

Journal Articles

Origin of (sporadic) Plasma Cell Myeloma: Lysolipids Are Not the Target of Clonal Immunoglobulins

Michael Pfreundschuh, MD, PhD, Natalie Fadle, Evi Regitz, Maria Kemele, Klaus-Dieter Preuss, PhD

Blood (2016) 128 (22): 2055.

https://doi.org/10.1182/blood.V128.22.2055.2055

Published: 2016

Journal Articles

CD3/Bars: A Novel Bispecific Format for the Treatment of B-Cell Lymphomas

Moritz Bewarder, MD, Klaus-Dieter Preuss, PhD, Natalie Fadle, Evi Regitz, Lorenz Thurner, MD, Michael Pfreundschuh, MD, PhD

Blood (2016) 128 (22): 3516.

https://doi.org/10.1182/blood.V128.22.3516.3516

Published: 2016

Journal Articles

BARs ( B -cell receptor a ntigens for r everse targeting): A Novel and Ultimately Specific Treatment Concept for B-Cell Neoplasms

Michael Pfreundschuh, MD, Lorenz Thurner, MD, Stefan Barth, Prof.Dr., Diana Pickert, Natalie Fadle, Maria Kemele, Evi Regitz, Frank Neumann, PhD, Thomas Nachreiner, Dr., Klaus-Dieter Preuss, PhD

Blood (2015) 126 (23): 3995.

https://doi.org/10.1182/blood.V126.23.3995.3995

Published: 2015

Journal Articles

LRPAP1 Is a Frequent B-Cell Receptor Antigen in Mantle Cell Lymphoma (MCL)

Lorenz Thurner, MD, Sylvia Hartmann, Klaus-Dieter Preuss, PhD, Natalie Fadle, Maria Kemele, Evi Regitz, Christiane Pott, MD PhD, Rainer-Maria Bohle, Martin-Leo Hansmann, Michael Pfreundschuh, MD

Blood (2015) 126 (23): 2685.

https://doi.org/10.1182/blood.V126.23.2685.2685

Published: 2015

Journal Articles

Peripheral B Cells from Patients with MGUS and Multiple Myeloma (MM) Can Be Stimulated by Paraprotein-Target Specific T-Helper Cells to Produce Paraprotein-Identical Monoclonal Antibodies: Rationale for PARs, a Novel Therapeutic Approach with Ultimate Specificity in MGUS/MM

Frank Neumann, PhD, Boris Kubuschok, MD, Klaus-Dieter Preuss, PhD, Claudia Schormann, Michael Pfreundschuh, MD

Blood (2015) 126 (23): 1817.

https://doi.org/10.1182/blood.V126.23.1817.1817

Published: 2015

Journal Articles

Sumoylated HSP-90 Is a Frequent Autosomal-Inherited Target of Paraproteins in Monoclonal Gammopathies

Klaus-Dieter Preuss, Natalie Fadle, Evi Regitz, Michael Pfreundschuh, Prof MD

Blood (2014) 124 (21): 26.

https://doi.org/10.1182/blood.V124.21.26.26

Published: 2014

Journal Articles

Identification of the Antigenic Targets of the Major CLL-Derived Stereotyped BCRs and First Demonstration of Sub-Subsets

Klaus-Dieter Preuss, Natalie Fadle, Evi Regitz, Maria Kemele, Manuela Wölfle, Stephan Stilgenbauer, MD, Michael Pfreundschuh, Prof MD

Blood (2014) 124 (21): 298.

https://doi.org/10.1182/blood.V124.21.298.298

Published: 2014

Journal Articles

Postranslationally Modified Proteins in the Central Nervous System (CNS) Are the Dominant Antigenic Target/Stimulus of the B-Cell Receptor (BCR) in Primary CNS Lymphomas (PCNSL) Providing Strong Evidence for the Role of Chronic Autoantigenic Stimulation As an Early Step in the Pathogenesis of Aggressive B-Cell Lymphomas

Lorenz Thurner, MD, Maria Kemele, Natalie Fadle, Evi Regitz, Patrick Roth, MD, Michael Weller, Prof., Monika Szczepanowski, Wolfram Klapper, Camelia-Maria Monoranu, MD, Andreas Rosenwald, MD, Rolf Buslei, MD, Rainer Maria Bohle, MD, Yoo-Jin Kim, MD, Klaus-Dieter Preuss, PhD, Michael Pfreundschuh

Blood (2014) 124 (21): 142.

https://doi.org/10.1182/blood.V124.21.142.142

Published: 2014

Journal Articles

Autoantigenic targets of B-cell receptors derived from chronic lymphocytic leukemias bind to and induce proliferation of leukemic cells

Carsten Zwick, Natalie Fadle, Evi Regitz, Maria Kemele, Stephan Stilgenbauer, Andreas Bühler, Michael Pfreundschuh, Klaus-Dieter Preuss

Blood (2013) 121 (23): 4708–4717.

https://doi.org/10.1182/blood-2012-08-447904

Published: 2013

Includes: Supplemental data

Journal Articles

Autoantigenic Targets of B-Cell Receptors (BCR) Derived From Chronic Lymphocytic Leukemias Bind to and Induce Proliferation of Leukemic Cells.

Klaus-Dieter Preuss, Gerhard Held, MD, Natalie Fadle, Evi Regitz, Maria Kemele, Stephan Stilgenbauer, MD, Andreas Buehler, MD, Michael Pfreundschuh, MD

Blood (2012) 120 (21): 2884.

https://doi.org/10.1182/blood.V120.21.2884.2884

Published: 2012

Journal Articles

New Insights in the Pathogenesis of MGUS, Multiple Myeloma (MM) and Waldenström`s Macroglobulinemia (WM): Chronic Antigenic Stimulation by Autoantigenic Targets of Paraproteins Is Mediated by CD4 + t-Cells

Sandra Grass, MD, Klaus-Dieter Preuss, Aleksandra Wikowicz, Natalie Fadle, Evi Regitz, Gerhard Held, Leon Bernal-Mizrachi, MD, Sybille Raudies, Holger Thiele, Michael Pfreundschuh, MD, Frank Neumann

Blood (2011) 118 (21): 472.

https://doi.org/10.1182/blood.V118.21.472.472

Published: 2011

Journal Articles

The impact of Fc-γ receptor polymorphisms in elderly patients with diffuse large B-cell lymphoma treated with CHOP with or without rituximab

Manfred Ahlgrimm, Michael Pfreundschuh, Markus Kreuz, Evi Regitz, Klaus-Dieter Preuss, Joerg Bittenbring

Blood (2011) 118 (17): 4657–4662.

https://doi.org/10.1182/blood-2011-04-346411

Published: 2011

Includes: Supplemental data

Journal Articles

Hyperphosphorylation of autoantigenic targets of paraproteins is due to inactivation of PP2A

Klaus-Dieter Preuss, Michael Pfreundschuh, Natalie Fadle, Evi Regitz, Sybille Raudies, Niels Murwaski, Manfred Ahlgrimm, Joerg Bittenbring, Markus Klotz, Karl-Herbert Schäfer, Gerhard Held, Frank Neumann, Sandra Grass

Blood (2011) 118 (12): 3340–3346.

https://doi.org/10.1182/blood-2011-04-351668

Published: 2011

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LRPAP1 autoantibodies in mantle cell lymphoma are associated with superior outcome

Identification and Characterization of CMV-Specific, HLA-C*07:02 Restricted Antibodies

The B-Cell Receptor Antigen ARS2 Can be Integrated into a BAR-Body Format to Treat Diffuse Large B-Cell Lymphomas in Xenograft Mouse Models

Hyper- N -glycosylated SAMD14 and neurabin-I as driver autoantigens of primary central nervous system lymphoma

Identification of Posttranvslationally Modified Neoantigens As Targets of B Cell Receptors of Burkitt Lymphoma

BAR-Bodies: B-Cell Receptor Antigens As the Targeting Moiety of Antibodies in Substitution for the Variable Region of Heavy and Light Chains

B-Cell Receptor Antigens As the Targeting Moiety for Bispecific Constructs - a Novel Treatment Approach for B-Cell Lymphomas

Origin of (sporadic) Plasma Cell Myeloma: Lysolipids Are Not the Target of Clonal Immunoglobulins

CD3/Bars: A Novel Bispecific Format for the Treatment of B-Cell Lymphomas

BARs ( B -cell receptor a ntigens for r everse targeting): A Novel and Ultimately Specific Treatment Concept for B-Cell Neoplasms

LRPAP1 Is a Frequent B-Cell Receptor Antigen in Mantle Cell Lymphoma (MCL)

Peripheral B Cells from Patients with MGUS and Multiple Myeloma (MM) Can Be Stimulated by Paraprotein-Target Specific T-Helper Cells to Produce Paraprotein-Identical Monoclonal Antibodies: Rationale for PARs, a Novel Therapeutic Approach with Ultimate Specificity in MGUS/MM

Sumoylated HSP-90 Is a Frequent Autosomal-Inherited Target of Paraproteins in Monoclonal Gammopathies

Identification of the Antigenic Targets of the Major CLL-Derived Stereotyped BCRs and First Demonstration of Sub-Subsets

Autoantigenic targets of B-cell receptors derived from chronic lymphocytic leukemias bind to and induce proliferation of leukemic cells

Autoantigenic Targets of B-Cell Receptors (BCR) Derived From Chronic Lymphocytic Leukemias Bind to and Induce Proliferation of Leukemic Cells.

New Insights in the Pathogenesis of MGUS, Multiple Myeloma (MM) and Waldenström`s Macroglobulinemia (WM): Chronic Antigenic Stimulation by Autoantigenic Targets of Paraproteins Is Mediated by CD4 + t-Cells

The impact of Fc-γ receptor polymorphisms in elderly patients with diffuse large B-cell lymphoma treated with CHOP with or without rituximab

Hyperphosphorylation of autoantigenic targets of paraproteins is due to inactivation of PP2A

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