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Klaus Strein, MD PhD
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Journal Articles

New Insights into the Mechanism of Action (MoA) of First-in-Class IgG-Based Bcma T-Cell Bispecific Antibody (TCB) for the Treatment of Multiple Myeloma (MM)

Laura Moreno, Aintzane Zabaleta, Diego Alignani, Marta Lasa, Patricia Maiso, PhD, Tomas Jelinek, MD, Victor Segura, PhD, Jose Antonio Delgado, Paula Rodriguez-Otero, MD PhD, Felipe Prosper, MD, Klaus Strein, MD PhD, Minh Diem Vu, PhD, Jesus San Miguel, MD PhD, Bruno Paiva, PhD
Journal: Blood
Blood (2016) 128 (22): 2096.
https://doi.org/10.1182/blood.V128.22.2096.2096
Published: 2016
Journal Articles

A New Class of T-Cell Bispecific Antibodies for the Treatment of Multiple Myeloma, Binding to B Cell Maturation Antigen and CD3 and Showing Potent, Specific Antitumor Activity in Myeloma Cells and Long Duration of Action in Cynomolgus Monkeys

Minh Diem Vu, PhD, Samuel Moser, MSc, Camille Delon, MSc, Melanie Latzko, MSc, Reto Gianotti, MSc, Remo Lüoend, BSc, Chloé Friang, MSc, Ramona Murr, MSc, Lydia Jasmin Duerner, PhD, Tina Weinzierl, PhD, Tanja Fauti, PhD, Marina Bacac, PhD, Oliver Ast, PhD, Anne Freimoser-Grundschober, PhD, Tea Rodriguez Diaz, MSc, Jörg Zielonka, PhD, Erwin van Puijenbroek, PhD, Ralf Hosse, PhD, Peter Bruenker, PhD, Ekkehard Mössner, PhD, Christian Klein, PhD, Pablo Umaña, PhD, Klaus Strein, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2998.
https://doi.org/10.1182/blood.V126.23.2998.2998
Published: 2015
Journal Articles

Target Expression, Preclinical Activity and Mechanism of Action of EM801: A Novel First-in-Class Bcma T-Cell Bispecific Antibody for the Treatment of Multiple Myeloma

Anja Seckinger, MD, Jose Antonio Delgado, Laura Moreno, Brigitte Neuber, PhD, Anna Grab, PhD, Susanne Lipp, MS, Juana Merino, MDPhD, Minh Diem Vu, PhD, Klaus Strein, MD PhD, Felipe Prosper, MDPhD, Michael Hundemer, MD, Jesus San Miguel, MDPhD, Dirk Hose, MD, Bruno Paiva, PhD
Journal: Blood
Blood (2015) 126 (23): 117.
https://doi.org/10.1182/blood.V126.23.117.117
Published: 2015