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Journal Articles

Superiority of IFN Versus HU Using a Novel Biomarker-Based Tool for Assessment of Disease Burden in MPNs

Vibe Skov, PhD, Marc JB Dam, Rasmus K Pedersen, Morten Andersen, PhD, Trine Alma Knudsen, MD, Zamra Sajid, Lasse Kjær, PhD, Christina Ellervik, MD PhD, Hans Hasselbalch, MD, Johnny T Ottesen, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2972.
https://doi.org/10.1182/blood-2019-126819
Published: 2019
Journal Articles

Significantly Upregulated Thrombo-Inflammatory Genes Are Normoregulated or Significantly Downregulated during Treatment with Interferon-Alpha2 in Patients with Philadelphia-Negative Chronic Myeloproliferative Neoplasms

Vibe Skov, PhD, Caroline Riley, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Thomas Stauffer Larsen, MD PhD, Torben A Kruse, Hans Hasselbalch, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2978.
https://doi.org/10.1182/blood-2019-131698
Published: 2019
Journal Articles

Highly Deregulated Fibulins in Patients with Philadelphia-Negative Chronic Myeloproliferative Neoplasms

Vibe Skov, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Thomas Stauffer Larsen, MD PhD, Torben A Kruse, Hans Hasselbalch, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5396.
https://doi.org/10.1182/blood-2019-130560
Published: 2019
Journal Articles

Genomic Profiling of a Phase III Clinical Trial of Interferon Versus Hydroxyurea in MPN Patients Reveals Mutation-Specific and Treatment-Specific Patterns of Response

Trine Alma Knudsen, MD, Vibe Skov, PhD, Lillian Werner, MS, William Duke, Christopher J. Gibson, MD, Anwesha Nag, PhD, Aaron R. Thorner, PhD, Bruce Wollison, MS, Dennis Lund Hansen, MD, Thomas Stauffer Larsen, MD PhD, Christina Ellervik, MD PhD, Daniel El Fassi, MD, Karin de Stricker, MD, Lukas Frans Ocias, MD, Mette Brabrand, Ole Weis Bjerrum, MD PhD, Ulrik Malthe Overgaard, MD, Mikael Frederiksen, MD, Thomas Kielsgaard Kristensen, Torben A Kruse, Mads Thomassen, PhD, Torben Mourits-Andersen, MD, Marianne Tang Severinsen, MD PhD, Jesper Stentoft, MD, Joern Starklint, Peter Møller, MD, Donna S Neuberg, ScD, Lasse Kjær, PhD, Hans Hasselbalch, MD, R. Coleman Lindsley, MD PhD, Ann Mullally, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4202.
https://doi.org/10.1182/blood-2019-126164
Published: 2019
Journal Articles

Interferon-alfa2 Treatment of Patients with Polycythemia Vera and Related Neoplasms Impacts Deregulation of Oxidative Stress Genes and Antioxidative Defence Mechanisms. Potential Implications of IFN-Alfa Induced Changes in TP53, NRF2 and CXCR4 for Genomic Instability and CD34+ Mobilisation

Vibe Skov, PhD, Caroline Riley, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Thomas Stauffer Larsen, MD PhD, Ole Weis Bjerrum, MD PhD, Torben A Kruse, Hans Carl Hasselbalch, Professor, dr.MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4326.
https://doi.org/10.1182/blood-2018-99-112109
Published: 2018
Journal Articles

The Impact of the Mutational Landscape upon the Molecular Responses to Interferon-Alfa2 in Calr-Mutated MPN Patients

Vibe Skov, PhD, Lasse Kjær, PhD, Mads Thomassen, PhD, Steffen Koschmieder, MD, Julia Czech, Nicolas Chatain, PhD, Niels Pallisgaard, Sabrina Cordua, MD, Torben A Kruse, Hans Carl Hasselbalch, Professor, dr.MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4327.
https://doi.org/10.1182/blood-2018-99-119158
Published: 2018
Journal Articles

The Impact of Interferon on Interferon-Related Genes in Polycythemia Vera and Allied Neoplasms

Vibe Skov, PhD, Caroline Riley, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Thomas Stauffer Larsen, MD PhD, Ole Weis Bjerrum, Torben A Kruse, Hans Carl Hasselbalch, Professor, dr.MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4328.
https://doi.org/10.1182/blood-2018-99-110602
Published: 2018
Journal Articles

Genetic Evidence for Involvement of Human Endogenous Retrovirus Herv-Fc1 in the Pathogenesis of MPNs

Vibe Skov, PhD, Katrine LM Schmidt, Kasper Mønsted Pedersen, MD, Bettina Hansen, Tobias Wirenfeldt Klausen, M.S., Torben A Kruse, Mads Thomassen, PhD, Lasse Kjær, PhD, Christina Ellervik, Associate Professor, MD PhD, Morten Holmstrøm, MD, Bjørn Nexø, Hans Carl Hasselbalch, Professor, dr.MD, Magdalena J Laska
Journal: Blood
Blood (2018) 132 (Supplement 1): 5488.
https://doi.org/10.1182/blood-2018-99-118080
Published: 2018
Journal Articles

Interferon-alfa2 Treatment of Patients with Polycythemia Vera and Related Neoplasms Influences Deregulated Inflammation and Immune Genes in Polycythemia Vera and Allied Neoplasms

Vibe Skov, PhD, Caroline Riley, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Thomas Stauffer Larsen, MD PhD, Ole Weis Bjerrum, MD PhD, Torben A Kruse, Hans Carl Hasselbalch, Professor, dr.MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5490.
https://doi.org/10.1182/blood-2018-99-118690
Published: 2018
Journal Articles

Extracellular Matrix-Related Genes Are Deregulated in Peripheral Blood from Patients with Myelofibrosis and Related Neoplasms

Vibe Skov, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Caroline Riley, PhD, Thomas Stauffer Larsen, MD PhD, Ole Weis Bjerrum, MD PhD, Torben A Kruse, Hans Carl Hasselbalch, Professor, dr.MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5491.
https://doi.org/10.1182/blood-2018-99-117122
Published: 2018
Journal Articles

Long-Term Efficacy and Safety of Recombinant Interferon Alpha-2 Vs. Hydroxyurea in Polycythemia Vera: Preliminary Results from the Three-Year Analysis of the Daliah Trial - a Randomized Controlled Phase III Clinical Trial

Trine Alma Knudsen, MD, Dennis Lund Hansen, MD, Lukas Frans Ocias, MD, Ole Weis Bjerrum, MD DMSc, Mette Brabrand, Daniel El Fassi, MD PhD, Mikael Frederiksen, MD, Lasse Kjær, PhD, Thomas Kielsgaard Kristensen, MSc, PhD, Torben A Kruse, Torben Mourits-Andersen, MD, Peter Møller, MD, Ulrik Malthe Overgaard, MD, Marianne Tang Severinsen, MD PhD, Vibe Skov, PhD, Jesper Stentoft, Professor, dr.MD, Jørn Starklint, MD, Karin de Stricker, MSc, PhD, Mads Thomassen, PhD, Thomas Stauffer Larsen, MD PhD, Hans Carl Hasselbalch, Professor, dr.MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 580.
https://doi.org/10.1182/blood-2018-99-111255
Published: 2018
Journal Articles

Whole Blood Transcriptional Profiling Reveals Highly Deregulated Atherosclerosis Genes in Myeloproliferative Cancer

Vibe Skov, PhD, Mads Thomassen, PhD, Lasse Kjær, PhD, Caroline Riley, PhD, Thomas Stauffer Larsen, MD PhD, Ole Weis Bjerrum, MD PhD, Torben A Kruse, Hans Carl Hasselbalch, Professor, dr.MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3071.
https://doi.org/10.1182/blood-2018-99-117981
Published: 2018
Journal Articles

A Heterogeneous Response Pattern to Interferon-alpha2 with Induction of a Significant Decrease in the Calreticulin Mutant Allele Burden in a Subset of Patients with Essential Thrombocythemia and Primary Myelofibrosis

Sabrina Cordua, MD, Lasse Kjaer, PhD, Morten Orebo Holmström, MD, Niels Pallisgaard, MSc, Vibe Skov, MSc, PhD, Hans Hasselbalch, MD
Journal: Blood
Blood (2015) 126 (23): 4057.
https://doi.org/10.1182/blood.V126.23.4057.4057
Published: 2015