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Journal Articles

Randomized Phase III Study (ADMYRE) of Plitidepsin in Combination with Dexamethasone Vs. Dexamethasone Alone in Patients with Relapsed/Refractory Multiple Myeloma

Blood (2017) 130 (Supplement 1): 1886.

https://doi.org/10.1182/blood.V130.Suppl_1.1886.1886

Published: 2017

Journal Articles

Serotonin Receptor Antagonists Have an In Vitro and In Vivo Anti-Myeloma Effect That Is Mainly Mediated by Caspase Dependent Apoptosis.

Enrique M. Ocio, MD, PhD, Teru Hideshima, MD, PhD, Hiroshi Yasui, MD, PhD, Kiziltepe Tanyel, PhD, Hirosi Ikeda, MD, PhD, Yutaka Okawa, MD, PhD, Sonia Vallet, MD, Janice Jin, MD, Kenji Ishitsuka, MD, PhD, Noopur Raje, MD, Laurence Catley, MD, MBBS, FRACP, Kenneth C. Anderson, MD

Blood (2006) 108 (11): 2597.

https://doi.org/10.1182/blood.V108.11.2597.2597

Published: 2006

Journal Articles

Epigenetic Modulation by Vidaza™ induces Apoptosis and Overcomes In Vitro Drug Resistance in Human Multiple Myeloma Cells.

Tanyel Kiziltepe, PhD, Laurence Catley, MD, Teru Hideshima, MD,PhD, Noopur Raje, MD, Hiroshi Yasui, MD,PhD, Sonia Vallet, MD, Hiroshi Ikeda, MD,PhD, Yutaka Okawa, MD,PhD, Kenneth C. Anderson, MD

Blood (2006) 108 (11): 5001.

https://doi.org/10.1182/blood.V108.11.5001.5001

Published: 2006

Journal Articles

Akt Inhibitor Perifosine-Induced Cytotoxicity Is Associated with Significant Downregulation of Survivin in Human Multiple Myeloma (MM) Cells.

Teru Hideshima, MD, PhD, Hiroshi Yasui, MD, PhD, Laurence Catley, MD, Noopur Raje, MD, Dharminder Chauhan, PhD, Kenji Ishitsuka, MD, PhD, Klaus Podar, MD, PhD, Constantine Mitsiades, MD, PhD, Yu-Tzu Tai, PhD, Sonia Vallet, MD, Tanyel Kizitepe, PhD, Enrique Ocio, MD, PhD, Hiroshi Ikeda, MD, PhD, Yutaka Okawa, MD, PhD, Hiromasa Hideshima, Nikhil C. Munshi, MD, Paul G. Richardson, MD, Kenneth C. Anderson, MD

Blood (2006) 108 (11): 3410.

https://doi.org/10.1182/blood.V108.11.3410.3410

Published: 2006

Journal Articles

Biological Pathways and In Vivo Anti-Tumor Activity Induced by Atiprimod in Multiple Myeloma (MM).

Paola Neri, MD, Pierfrancesco Tassone, MD, Masood Shammas, PhD, Hiroshi Yasui, MD, Ernestina Schipani, MD, Ramesh B. Batchu, PhD, Simona Blotta, MD, Rao Prabhala, PhD, Laurence Catley, MD, Makoto Hamasaki, MD, Teru Hideshima, MD, Dharminder Chauhan, PhD, Gary S. Jacob, PhD, Donald Picker, PhD, Salvatore Venuta, MD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2006) 108 (11): 3455.

https://doi.org/10.1182/blood.V108.11.3455.3455

Published: 2006

Journal Articles

Novel Murine Model To Study Modulation of Genes and Molecular Pathways Induced Following In Vivo Interaction between Multiple Myeloma Cells and Human BM Milieu.

Paola Neri, MD, Pierfrancesco Tassone, MD, Masood Shammas, PhD, Mariateresa Fulciniti, PhD, Yu-Tzu Tai, PhD, Simona Blotta, MD, Rao Prabhala, PhD, Mariateresa Di Martino, PhD, Laurence Catley, MD, Pierosandro Tagliaferri, MD, Salvatore Venuta, MD, Ruben Carrasco, MD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2006) 108 (11): 3409.

https://doi.org/10.1182/blood.V108.11.3409.3409

Published: 2006

Journal Articles

In Vitro Generation of Highly Purified Functional Invariant NKT Cells in Multiple Myeloma: A Strategy for Immunotherapy.

Weihua Song, MD, Hans J.J. van der Vliet, MD, Yu-Tzu Tai, PhD, Ruojie Wang, MD, Rao Prabhala, PhD, Klaus Podar, MD, Laurence Catley, MD, Masood Shammas, PhD, Steven P. Balk, MD, Kenneth C. Anderson, MD, Mark A. Exley, PhD, Nikhil C. Munshi, MD

Blood (2006) 108 (11): 5104.

https://doi.org/10.1182/blood.V108.11.5104.5104

Published: 2006

Journal Articles

JS-K, a GST-Activated Nitric Oxide Generator, Induces Apoptosis and Overcomes In Vitro Drug Resistance in Multiple Myeloma Cells.

Tanyel Kiziltepe, PhD, Kenji Ishitsuka, MD, PhD, Teru Hideshima, MD, PhD, Noopur Raje, MD, Norihiko Shiraishi, PhD, Hiroshi Yasui, MD, PhD, Laurence Catley, MD, Dharminder Chauhan, PhD, Joseph E. Saavedra, PhD, Larry K. Keefer, PhD, Paul J. Shami, MD, Kenneth C. Anderson, MD

Blood (2005) 106 (11): 1593.

https://doi.org/10.1182/blood.V106.11.1593.1593

Published: 2005

Journal Articles

In Vitro Generation of Highly-Purified Functional Invariant NKT Cells: A Strategy for Immunotherapy in Multiple Myeloma.

Weihua Song, MD, Hans J.J. van der Vliet, MD, PhD, Ruojie Wang, MD, Rao Prabhala, PhD, Klaus Podar, MD, Yu-Tzu Tai, PhD, Laurence Catley, MD, Masood Shammas, PhD, Kenneth C. Anderson, MD, Steven P. Balk, MD, Mark A. Exley, PhD, Nikhil C. Munshi, MD

Blood (2005) 106 (11): 5183.

https://doi.org/10.1182/blood.V106.11.5183.5183

Published: 2005

Journal Articles

Immunomodulatory Drug Lenalidomide (CC-5013, IMiD3) Augments Anti-CD40 SGN-40-Induced Cytotoxicity in Human Multiple Myeloma: Clinical Implications.

Yu-Tzu Tai, PhD, Laurence Catley, MD, Xian-Feng Li, MS, Rory Coffey, BS, Iris Breitkreutz, MD, Jooeun Bae, PhD, Klaus Podar, MD, PhD, Teru Hideshima, MD, PhD, Dharminder Chauhan, PhD, Robert Schlossman, MD, Paul Richardson, MD, Steven P. Treon, MD, PhD, Iqbal S. Grewal2, PhD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD

Blood (2005) 106 (11): 5150.

https://doi.org/10.1182/blood.V106.11.5150.5150

Published: 2005

Journal Articles

The JAK Inhibitor INCB20 Induces Antiproliferative and Apoptotic Effects in Human Myeloma Cells In Vitro and In Vivo .

Renate Burger, PhD, Steven Legouill, MD, Yu-Tzu Tai, PhD, Reshma Shringarpure, PhD, Klaus Podar, MD, PhD, Laurence Catley, MD, Pierfrancesco Tassone, MD, Paola Neri, MD, Teru Hideshima, MD, Dharminder Chauhan, PhD, Eian Caulder, BS, Kris Vaddi, PhD, Claire L. Neilan, PhD, Martin Gramatzki, MD, Jordan S. Fridman, PhD, Kenneth C. Anderson, MD

Blood (2005) 106 (11): 3357.

https://doi.org/10.1182/blood.V106.11.3357.3357

Published: 2005

Journal Articles

In Vivo Anti-Tumor Activity of Atiprimod on SCID Models of Multiple Myeloma.

Paola Neri, MD, Pierfrancesco Tassone, MD, Masood A. Shammas, PhD, Ramesh B. Batchu, PhD, Simona Blotta, MD, Sushma Samala, PhD, Laurence Catley, MD, Makoto Hamasaki, PhD, Teru Hideshima, MD, Gary S. Jacob, PhD, Donald H. Picker, PhD, Salvatore Venuta, MD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2005) 106 (11): 249.

https://doi.org/10.1182/blood.V106.11.249.249

Published: 2005

Journal Articles

Novel Model To Evaluate Changes in Gene Expression Profile of Myeloma Cells In Vivo Following Interaction with Human BM Microenvironment.

Paola Neri, MD, Pierfrancesco Tassone, MD, Masood A. Shammas, PhD, Daniel R. Carrasco, MD, Renate Burger, PhD, Constantine S. Mitsdiades, MD, Simona Blotta, MD, Rao H. Prabhala, PhD, Laurence Catley, MD, Salvatore Venuta, MD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2005) 106 (11): 2490.

https://doi.org/10.1182/blood.V106.11.2490.2490

Published: 2005

Journal Articles

Perifosine, an Oral Bioactive Novel Alkyl-Phospholipid, Inhibits Akt and Induces In Vitro and In Vivo Cytotoxicity in Human Multiple Myeloma (MM) Cells.

Teru Hideshima, MD, PhD, Laurence Catley, MD, Hiroshi Yasui, MD, PhD, Kenji Ishitsuka, MD, PhD, Noopur Raje, MD, Constantine Mitsiades, MD, PhD, Klaus Podar, MD, PhD, Nikhil C. Munshi, MD, Dharminder Chauhan, PhD, Paul G. Richardson, MD, Kenneth C. Anderson, MD

Blood (2005) 106 (11): 250.

https://doi.org/10.1182/blood.V106.11.250.250

Published: 2005

Journal Articles

Inhibition of Human Plasmacytoma Cell Growth by a Novel JAK Kinase Inhibitor.

Blood (2004) 104 (11): 644.

https://doi.org/10.1182/blood.V104.11.644.644

Published: 2004

Journal Articles

A Clinically Relevant SCID-hu in Vivo Model of Human Multiple Myeloma.

Pierfrancesco Tassone, MD, Paola Neri, MD, Daniel R. Carrasco, MD, Renate Burger, PhD, Laurence Catley, MD, Salvatore Venuta, MD, PhD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2004) 104 (11): 2455.

https://doi.org/10.1182/blood.V104.11.2455.2455

Published: 2004

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Randomized Phase III Study (ADMYRE) of Plitidepsin in Combination with Dexamethasone Vs. Dexamethasone Alone in Patients with Relapsed/Refractory Multiple Myeloma

Serotonin Receptor Antagonists Have an In Vitro and In Vivo Anti-Myeloma Effect That Is Mainly Mediated by Caspase Dependent Apoptosis.

Epigenetic Modulation by Vidaza™ induces Apoptosis and Overcomes In Vitro Drug Resistance in Human Multiple Myeloma Cells.

Akt Inhibitor Perifosine-Induced Cytotoxicity Is Associated with Significant Downregulation of Survivin in Human Multiple Myeloma (MM) Cells.

Biological Pathways and In Vivo Anti-Tumor Activity Induced by Atiprimod in Multiple Myeloma (MM).

Novel Murine Model To Study Modulation of Genes and Molecular Pathways Induced Following In Vivo Interaction between Multiple Myeloma Cells and Human BM Milieu.

In Vitro Generation of Highly Purified Functional Invariant NKT Cells in Multiple Myeloma: A Strategy for Immunotherapy.

JS-K, a GST-Activated Nitric Oxide Generator, Induces Apoptosis and Overcomes In Vitro Drug Resistance in Multiple Myeloma Cells.

In Vitro Generation of Highly-Purified Functional Invariant NKT Cells: A Strategy for Immunotherapy in Multiple Myeloma.

Immunomodulatory Drug Lenalidomide (CC-5013, IMiD3) Augments Anti-CD40 SGN-40-Induced Cytotoxicity in Human Multiple Myeloma: Clinical Implications.

The JAK Inhibitor INCB20 Induces Antiproliferative and Apoptotic Effects in Human Myeloma Cells In Vitro and In Vivo .

In Vivo Anti-Tumor Activity of Atiprimod on SCID Models of Multiple Myeloma.

Novel Model To Evaluate Changes in Gene Expression Profile of Myeloma Cells In Vivo Following Interaction with Human BM Microenvironment.

Perifosine, an Oral Bioactive Novel Alkyl-Phospholipid, Inhibits Akt and Induces In Vitro and In Vivo Cytotoxicity in Human Multiple Myeloma (MM) Cells.

Inhibition of Human Plasmacytoma Cell Growth by a Novel JAK Kinase Inhibitor.

A Clinically Relevant SCID-hu in Vivo Model of Human Multiple Myeloma.

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American Society of Hematology

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