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Journal Articles

Structural Features of ROR1 Required for Complexing with ROR2 and Enhancing Chemokine-Induced Migration and Leukemia-Cell Proliferation, Which Can be Blocked By the Anti-ROR1 Mab Cirmtuzumab (UC-961)

Jian Yu, PhD, Liguang Chen, MD PhD, George F. Widhopf, II, PhD, Suping Zhang, PhD, Bing Cui, PhD, Rongrong Wu, PhD, Ling Zhang, PhD, Thomas J. Kipps, MD, PhD

Blood (2015) 126 (23): 1741.

https://doi.org/10.1182/blood.V126.23.1741.1741

Published: 2015

Journal Articles

High-Level Expression of ROR1 Associates with Early Disease Progression in Patients with Chronic Lymphocytic Leukemia

Bing Cui, PhD, Liguang Chen, MD PhD, Laura Z. Rassenti, PhD, Emanuela M. Ghia, PhD, Jian Yu, PhD, Ling Zhang, PhD, Donna S Neuberg, ScD, William Wierda, MD PhD, Michael Keating, MBBS, Kanti R. Rai, MD, Neil E. Kay, MD, Jennifer R. Brown, MD PhD, John C. Byrd, MD, John Gribben, MDDSc, Thomas J. Kipps, MD, PhD

Blood (2015) 126 (23): 1713.

https://doi.org/10.1182/blood.V126.23.1713.1713

Published: 2015

Journal Articles

ROR1 Negative Chronic Lymphocytic Leukemia (CLL) Have a Distinctive Gene Expression Signature and May Represent an Indolent-Disease Subtype

Emanuela M. Ghia, PhD, Laura Z. Rassenti, PhD, Liguang Chen, MD PhD, Bing Cui, PhD, Christopher Deboever, BS, Kelly A. Frazer, Thomas J. Kipps, MD, PhD

Blood (2015) 126 (23): 2932.

https://doi.org/10.1182/blood.V126.23.2932.2932

Published: 2015

Journal Articles

Preclinical Development Of ROR1 Peptide Based Vaccine With Activity Against Chronic Lymphocytic Leukemia In ROR1 Transgenic Mice

Jian Yu, PhD, Bing Cui, Ph.D., George F. Widhopf, II, PhD, Liguang Chen, MD, PhD, Laura Rassenti, PhD, Zhengran Wang, BS, Shuyu Ma, BS, Tomoko Hayashi, M.D., Ph.D., Dennis A. Carson, M.D., Thomas J. Kipps, MD, PhD

Blood (2013) 122 (21): 4174.

https://doi.org/10.1182/blood.V122.21.4174.4174

Published: 2013

Journal Articles

ROR1 Can Interact With TCL1 and Enhance Leukemogenesis In Eµ-TCL1 Transgenic Mice

George F. Widhopf, II, PhD, Bing Cui, Ph.D., Emanuela M. Ghia, PhD, Liguang Chen, MD, PhD, Karen Messer, PhD, Zhouxin Shen, Steven P. Briggs, Ph.D, Carlo M. Croce, MD, Thomas J. Kipps, MD, PhD

Blood (2013) 122 (21): 868.

https://doi.org/10.1182/blood.V122.21.868.868

Published: 2013

Journal Articles

The Target Genes and Prognostic Significance of Mir-150 in Chronic Lymphocytic Leukemia

Marek Mraz, MD, PhD, Laura Z. Rassenti, Ph.D., Emanuela M. Ghia, PhD, Liguang Chen, MD, PhD, Jessie-Farah Fecteau, Ph.D., Sarka Pospisilova, Dr, PhD, Hongying Li, PhD, Karen Messer, PhD, Thomas J. Kipps, MD, PhD

Blood (2012) 120 (21): 3859.

https://doi.org/10.1182/blood.V120.21.3859.3859

Published: 2012

Journal Articles

Human ROR1 Activates AKT and Accelerates Leukemia Cell Proliferation

Suping Zhang, PhD, Liguang Chen, MD, PhD, Ling Zhang, Jian Yu, PhD, Laura Z. Rassenti, Ph.D., Thomas J. Kipps, MD, PhD

Blood (2012) 120 (21): 3872.

https://doi.org/10.1182/blood.V120.21.3872.3872

Published: 2012

Journal Articles

Highly Specific Inhibitor for Syk Induces Chronic Lymphocytic Leukemia Cell Apoptosis,

Liguang Chen, MD, PhD, George Chen, B.S., Jessie-Farah Fecteau, Ph.D., Greg Coffey, PhD, Charles Prussak, PhD, Dennis A. Carson, MD, Thomas Kipps, MD

Blood (2011) 118 (21): 3875.

https://doi.org/10.1182/blood.V118.21.3875.3875

Published: 2011

Journal Articles

Mir-155 Contributed to Chronic Lymphocytic Leukemia Survival by Modulation of BCR-Signalling

Liguang Chen, MD, PhD, Bing Cui, PhD, George Chen, B.S., Michelle Salcedo, BS, Carlo M. Croce, MD, Thomas J. Kipps, M.D., Ph.D

Blood (2011) 118 (21): 620.

https://doi.org/10.1182/blood.V118.21.620.620

Published: 2011

Journal Articles

Targeting of Chronic Lymphocytic Leukemia B Cells with a Novel Monoclonal Antibody to ROR1

Bing CUi, PhD, George F. Widhopf, II, PhD, Jian Yu, PhD, Daniel Martinez, BS, Esther Avery, B.S., Suping Zhang, PhD, Liguang Chen, MD, PhD, Rongrong Wu, Christina C.N. Wu, Ph.D., Charles Prussak, PhD, Thomas J. Kipps, M.D., Ph.D

Blood (2011) 118 (21): 984.

https://doi.org/10.1182/blood.V118.21.984.984

Published: 2011

Journal Articles

In Vitro Propagation of Mesenchymal Stromal Cells From Marrow Aspirates of Patients with Chronic Lymphocytic Leukemia Is Dependent Upon Physiologic Oxygen Tension

Jessie-Farah Fecteau, Ph.D., Davorka Messmer, PhD, Suping Zhang, PhD, Bing Cui, PhD, Liguang Chen, MD, PhD, Thomas J. Kipps, M.D., Ph.D

Blood (2011) 118 (21): 2839.

https://doi.org/10.1182/blood.V118.21.2839.2839

Published: 2011

Journal Articles

Influence of Mir-155 On B-Cell Receptor Signaling in Chronic Lymphocytic Leukemia.

Liguang Chen, MD, PhD, Bing Cui, PhD, George Chen, Michelle Salcedo, Carlo M. Croce, MD, Thomas J. Kipps, MD, PhD

Blood (2009) 114 (22): 2343.

https://doi.org/10.1182/blood.V114.22.2343.2343

Published: 2009

Journal Articles

Association Between the Proficiency of B-Cell Receptor Signaling and the Relative Expression Levels of ZAP-70, SHIP-1, and Mir-155 in Chronic Lymphocytic Leukemia

Liguang Chen, MD, PhD, Bing Cui, PhD, Suping Zhang, PhD, George Chen, Carlo M. Croce, MD, Thomas J. Kipps, MD, PhD

Blood (2008) 112 (11): 3155.

https://doi.org/10.1182/blood.V112.11.3155.3155

Published: 2008

Journal Articles

Expression of ROR1 in Chronic Lymphocytic Leukemia Cells Enhances Cells Survival by Wnt5a Signaling.

Liguang Chen, MD, PhD, Li Tang, M.D., Ph.D., Tetsu Fukuda, M.D., Ph.D., Thomas J. Kipps, M.D., Ph.D.

Blood (2007) 110 (11): 340.

https://doi.org/10.1182/blood.V110.11.340.340

Published: 2007

Journal Articles

Activation of AKT and Enhanced Resistance to Apoptosis Induced by Surface IgM Ligation in ZAP-70-Positive Chronic Lymphocytic Leukemia B Cells.

Liguang Chen, MD, PhD, Gabriel A. Meraz, BS, Thomas J. Kipps, MD, PhD

Blood (2005) 106 (11): 2940.

https://doi.org/10.1182/blood.V106.11.2940.2940

Published: 2005

NARROW

Structural Features of ROR1 Required for Complexing with ROR2 and Enhancing Chemokine-Induced Migration and Leukemia-Cell Proliferation, Which Can be Blocked By the Anti-ROR1 Mab Cirmtuzumab (UC-961)

High-Level Expression of ROR1 Associates with Early Disease Progression in Patients with Chronic Lymphocytic Leukemia

ROR1 Negative Chronic Lymphocytic Leukemia (CLL) Have a Distinctive Gene Expression Signature and May Represent an Indolent-Disease Subtype

Preclinical Development Of ROR1 Peptide Based Vaccine With Activity Against Chronic Lymphocytic Leukemia In ROR1 Transgenic Mice

ROR1 Can Interact With TCL1 and Enhance Leukemogenesis In Eµ-TCL1 Transgenic Mice

The Target Genes and Prognostic Significance of Mir-150 in Chronic Lymphocytic Leukemia

Human ROR1 Activates AKT and Accelerates Leukemia Cell Proliferation

Highly Specific Inhibitor for Syk Induces Chronic Lymphocytic Leukemia Cell Apoptosis,

Mir-155 Contributed to Chronic Lymphocytic Leukemia Survival by Modulation of BCR-Signalling

Targeting of Chronic Lymphocytic Leukemia B Cells with a Novel Monoclonal Antibody to ROR1

In Vitro Propagation of Mesenchymal Stromal Cells From Marrow Aspirates of Patients with Chronic Lymphocytic Leukemia Is Dependent Upon Physiologic Oxygen Tension

Influence of Mir-155 On B-Cell Receptor Signaling in Chronic Lymphocytic Leukemia.

Association Between the Proficiency of B-Cell Receptor Signaling and the Relative Expression Levels of ZAP-70, SHIP-1, and Mir-155 in Chronic Lymphocytic Leukemia

Expression of ROR1 in Chronic Lymphocytic Leukemia Cells Enhances Cells Survival by Wnt5a Signaling.

Activation of AKT and Enhanced Resistance to Apoptosis Induced by Surface IgM Ligation in ZAP-70-Positive Chronic Lymphocytic Leukemia B Cells.

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American Society of Hematology

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American Society of Hematology

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