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Mahmoud Ghandi, PhD
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Journal Articles

Resistance to SL-401 in AML and BPDCN Is Associated with Loss of the Diphthamide Synthesis Pathway Enzyme DPH1 and Is Reversible By Azacitidine

Jason Stephansky, Katsuhiro Togami, MDPhD, Mahmoud Ghandi, PhD, Joan Montero, PhD, Nick vonEgypt, Ross Lindsay, PhD, Christopher Brooks, PhD, Jon C. Aster, MD PhD, Cory Johannessen, PhD, Andrew A. Lane, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 797.
https://doi.org/10.1182/blood.V130.Suppl_1.797.797
Published: 2017
Journal Articles

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Harbors Frequent Splicesosome Mutations That Cause Aberrant RNA Splicing Affecting Genes Critical in pDC Differentiation and Function

Katsuhiro Togami, MD PhD, Vikas Madan, PhD, Jia Li, PhD, Alexandra-Chloe Villani, PhD, Siranush Sarkizova, BS, Mahmoud Ghandi, PhD, Kevin Buczkowski, BS, Yvonne Li, PhD, Sabeha Biichle, BS, Fanny Angelot-Delettre, PhD, Michael Seiler, PhD, Silvia Buonamici, PhD, Justin Taylor, MD, Omar Abdel-Wahab, MD, Peter S Hammerman, MD PhD, Nir Hacohen, PhD, Henry Yang, PhD, Francine Garnache-Ottou, PhD, H. Phillip Koeffler, MD PhD, Andrew A. Lane, MD PhD
Journal: Blood
Blood (2016) 128 (22): 738.
https://doi.org/10.1182/blood.V128.22.738.738
Published: 2016
Journal Articles

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Patient-Derived Xenografts Are Faithful Genomic and Phenotypic Models of Primary Leukemia and Respond to the IL3 Receptor Targeting Agent SL-401 In Vivo

Amanda L Christie, B.S., Yvonne Li, PhD, Katsuhiro Togami, MD, Mahmoud Ghandi, PhD, Alexandra N. Christodoulou, M.S., Kevin Buczkowski, Fanny Angelot-Delettre, PhD, Sabeha Biichle, Janice Chen, PhD, Christopher L. Brooks, PhD, David M. Weinstock, MD, Francine Garnache-Ottou, PhD, Peter S Hammerman, MD PhD, Andrew A Lane, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3797.
https://doi.org/10.1182/blood.V126.23.3797.3797
Published: 2015
Journal Articles

Increased Local Disorder of DNA Methylation Forms the Basis of High Intra-Leukemic Epigenetic Heterogeneity and Enhances CLL Evolution

Dan-Avi Landau, MD, PhD, Kendell Clement, Patrick Boyle, Michael Ziller, PhD, Kristen E. Stevenson, MS, Dylan Kotliar, Gordon Saksena, M. Eng, Carrie Sougnez, Wandi Zhang, Mahmoud Ghandi, PhD, Levi Garraway, MD, PhD, Stacey Gabriel, PhD, Eric S. Lander, PhD, Jennifer R. Brown, M.D., Donna S. Neuberg, ScD, Nir Hacohen, PhD, Gad Getz, Alexander Meissner, Ph.D., Catherine J. Wu, MD
Journal: Blood
Blood (2013) 122 (21): 596.
https://doi.org/10.1182/blood.V122.21.596.596
Published: 2013