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Maria Gkotzamanidou, MD, PhD
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Journal Articles

Ongoing Spontaneous DNA Damage Creates Synthetic Lethality Targeted By Novel RAD51 Inhibitors in Multiple Myeloma

Subodh Kumar, PhD, Maria Gkotzamanidou, MD PhD, Srikanth Talluri, PhD, Melinda Day, PhD, Mychell Neptune, Lakshmi B. Potluri, Chandraditya Chakraborty, PhD, Kevin Mills, PhD, Masood A. Shammas, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4378.
https://doi.org/10.1182/blood-2019-129121
Published: 2019
Journal Articles

HDAC8 Maintain Cytoskeleton Integrity Via Homologous Recombination and Represent a Novel Therapeutic Target in Multiple Myeloma

Zuzana Chyra, PhD, Maria Gkotzamanidou, MD PhD, Masood A. Shammas, PhD, Vassilis L. Souliotis, PhD, Yan Xu, MD, Mehmet K. Samur, PhD, Aaron B. Beeler, PhD, Roman Hajek, MD, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4385.
https://doi.org/10.1182/blood-2019-130700
Published: 2019
Journal Articles

Panobinostat Potentiates Melphalan-Induced Apoptosis of Myeloma Cells and Minimizes Untoward Side Effects in Multiple Myeloma

Maria Gkotzamanidou, MD PhD, Vassilis L. Souliotis, PhD, Meletios A. Dimopoulos, MD, Evangelos Terpos, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2528.
https://doi.org/10.1182/blood-2019-123338
Published: 2019
Journal Articles

Accumulation of Endogenous DNA Damage Sustain Malignant Progression and Increase Therapy Resistance in Multiple Myeloma

Maria Gkotzamanidou, MD PhD, Evangelos Terpos, MD PhD, Nikhil C. Munshi, MD, Vassilis L. Souliotis, PhD, Meletios A. Dimopoulos, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1788.
https://doi.org/10.1182/blood-2019-123502
Published: 2019
Journal Articles

Bone Marrow Microenvironment Regulates Alternative Splicing Events in Myeloma Cells through Downregulation of RNA Binding Protein Fox2

Weihua Song, MD, Chaolin Zhang, PhD, Yiguo Hu, PhD, Maria Gkotzamanidou, MD PhD, Parantu Shah, Weisong Shan, MDPhD, Guang Yang, PhD, Yi Li, Adam Sperling, MD PhD, Naim Rashid, PhD, Mehmet Kemal Samur, PhD, Samir B. Amin, MBBS, Yu-Tzu Tai, Teru Hideshima, MDPhD, Giovanni Parmigiani, PhD, Florence Magrangeas, PhD, Stephane Minvielle, PhD, Hervé Avet-Loiseau, MD PhD, Kenneth C. Anderson, Cheng Li, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2014) 124 (21): 4714.
https://doi.org/10.1182/blood.V124.21.4714.4714
Published: 2014
Journal Articles

Ongoing Spontaneous DNA Damage and the Role of Aberrant Epigenome in Multiple Myeloma

Maria Gkotzamanidou, MD PhD, Masood Shammas, PhD, Vassilis L. Souliotis, Weihua Song, MD, Jagannath Pal, MBBS, PhD, Puru Nanjappa, MS, Naim Rashid, PhD, Kenneth C. Anderson, MD, Meletios A. Dimopoulos, MD, James Bradner, MD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2014) 124 (21): 3398.
https://doi.org/10.1182/blood.V124.21.3398.3398
Published: 2014
Journal Articles

LSD1 Impairs the Epithelial-Mesenchymal Transition (EMT) and Osteoclastogenesis Potency in Multiple Myeloma and Synergistically Induces Cytotoxicity with HDAC Inhibitors

Maria Gkotzamanidou, MD PhD, Mariateresa Fulciniti, PhD, Jesús Martín Sanchez, Mehmet Kemal Samur, PhD, Giovanni Parmigiani, PhD, Kenneth C. Anderson, Nikhil C. Munshi, MD
Journal: Blood
Blood (2014) 124 (21): 3410.
https://doi.org/10.1182/blood.V124.21.3410.3410
Published: 2014
Journal Articles

HDAC8 Mediates Homologous Recombination and Cytoskeleton Integrity in Myeloma with Potential Impact on Cell Growth and Survival

Maria Gkotzamanidou, MD PhD, Masood Shammas, PhD, Jesus Martin Sanchez, MD, Lai Ding, Stephane Minvielle, Florence Magrangeas, Herve Avet-Loiseau, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2014) 124 (21): 416.
https://doi.org/10.1182/blood.V124.21.416.416
Published: 2014
Journal Articles

Telomerase-Mediated Repair of Induced DNA Breaks Leads to Increased Genomic Instability in Multiple Myeloma Cells: Possible Mechanism and Translational Significance

Jagannath Pal, PhD, Masood Shammas, PhD, Subodh Kumar, PhD, Maria Gkotzamanidou, MD PhD, Puru Nanjappa, MS, Leutz Buon, Nikhil C. Munshi, MD
Journal: Blood
Blood (2014) 124 (21): 5170.
https://doi.org/10.1182/blood.V124.21.5170.5170
Published: 2014
Journal Articles

Dysregulation of SHFM1, a Novel Target for Prevention of Genomic Instability in Myeloma, Is Associated with Epigenetic Changes at Specific CpG Sites

Masood Shammas, PhD, Subodh Kumar, PhD, Jagannath Pal, PhD, Puru Nanjappa, MS, Mehmat Samur, PhD, Maria Gkotzamanidou, MD PhD, Jialan Shi, MD PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2014) 124 (21): 862.
https://doi.org/10.1182/blood.V124.21.862.862
Published: 2014
Journal Articles

Elevated APE1 Mediates Dysregulation of Homologous Recombination in Myeloma: Mechanisms and Translational Significance

Subodh Kumar, PhD, Maria Gkotzamanidou, MD PhD, Jagannath Pal, PhD, Renquan Lu, MD PhD, Puru Nanjappa, MS, Jialan Shi, MD PhD, Masood Shammas, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2014) 124 (21): 2074.
https://doi.org/10.1182/blood.V124.21.2074.2074
Published: 2014
Journal Articles

Inhibition Of H3K27-Methylome As a Novel Therapeutic Strategy In Multiple Myeloma

Maria Gkotzamanidou, MD, PhD, Masood A Shammas, PhD, Jun Qi, PhD, Mehmet Kemal Samur, PhD, Teru Hideshima, MD, PhD, Meletios A. Dimopoulos, MD, Kenneth C. Anderson, MD, James E Bradner, MD, Nikhil Munshi, MD
Journal: Blood
Blood (2013) 122 (21): 3162.
https://doi.org/10.1182/blood.V122.21.3162.3162
Published: 2013
Journal Articles

Spontaneous DNA Damage and Aberrant Epigenome In Multiple Myeloma Constitute The Path To Disease Genomic Instability

Maria Gkotzamanidou, MD, PhD, Masood A. Shammas, Vassilis L. Souliotis, Jagannath Pal, MD, Jun Qi, Ph.D., Andrew Brown, James E Bradner, MD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2013) 122 (21): 4884.
https://doi.org/10.1182/blood.V122.21.4884.4884
Published: 2013