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Journal Articles

HLA-DM Mediates Permissiveness of HLA-DPB1 T Cell Epitope Mismatches in Unrelated HCT

Maximilian Metzing, Pietro Crivello, Thuja Meurer, Michel G.D. Kester, ing., Dominik Megger, Weiqiang Chen, Peter Van Balen, MD, Marieke Griffioen, PhD, Peter A. Horn, Barbara Sitek, J.H.Frederik Falkenburg, MD PhD, Esteban Arrieta-Bolaños, Katharina Fleischhauer, MD

Blood (2019) 134 (Supplement_1): 3211.

https://doi.org/10.1182/blood-2019-129921

Published: 2019

Journal Articles

Whole Transcriptome RNA Sequencing As a Comprehensive Diagnostic Tool for Acute Myeloid Leukemia

Blood (2018) 132 (Supplement 1): 2762.

https://doi.org/10.1182/blood-2018-99-111115

Published: 2018

Journal Articles

Fusion Transcripts without Corresponding Cytogenetic Abnormalities in Acute Myeloid Leukemia: Implications for AML Pathogenesis

Irene J. Locher, Wibowo Arindrarto, M.Sc., Daniel M. Borràs, M.Sc., M. Willy Honders, ing., Rick H. de Leeuw, ing., Wilma G.M. Kroes, PhD, Peter de Knijff, PhD, Cornelis A.M. van Bergen, PhD, Peter A.C. 't Hoen, PhD, Szymon M. Kielbasa, PhD, Jeroen F.J. Laros, PhD, Marieke Griffioen, PhD, Hendrik Veelken, MD PhD

Blood (2017) 130 (Supplement 1): 2703.

https://doi.org/10.1182/blood.V130.Suppl_1.2703.2703

Published: 2017

Journal Articles

Mutated NPM1 As Target for Immunotherapy of Acute Myeloid Leukemia

Dyantha I. Van Der Lee, BSc., Helena M. Bijen, MSc, Renate S. Hagedoorn, ing., Willy M. Honders, ing., Michel G.D. Kester, ing., Dirk M. van der Steen, ing., Arnoud H. de Ru, ing., Inge Jedema, PhD, Hendrik Veelken, MD PhD, Mirjam H.M. Heemskerk, PhD, Peter A. van Veelen, PhD, J.H. Frederik Falkenburg, MD PhD, Marieke Griffioen, PhD

Blood (2017) 130 (Supplement 1): 168.

https://doi.org/10.1182/blood.V130.Suppl_1.168.168

Published: 2017

Journal Articles

Primary Mediastinal Large B-Cell Lymphoma Exhibits Autonomous BCR Signaling and Responds to the Second Generation BTK Inhibitor Acalabrutinib

Marvyn T. Koning, BSc, Rudolf Übelhart, PhD, Sander A.J. van der Zeeuw, BSc, Philip Kluin, MD PhD, Marieke Griffioen, PhD, Hans G. Drexler, MD PhD, Szymon M. Kielbasa, PhD, Marcelo A. Navarrete, MD PhD, Hassan Jumaa, PhD, Hendrik Veelken, MD PhD

Blood (2016) 128 (22): 4171.

https://doi.org/10.1182/blood.V128.22.4171.4171

Published: 2016

Journal Articles

Endogenous Immunoglobulin-Derived Neoepitopes Are Processed and Form a Sizeable Fraction of the HLA Class I Ligandome of Human Lymphoma Cells

Cornelis A.M. van Bergen, PhD, Dirk M. van der Steen, Michel G.D. Kester, Marvyn T. Koning, BSc, Peter A. van Veelen, PhD, Marieke Griffioen, PhD, J.H. Frederik Falkenburg, MD PhD, Mirjam H.M. Heemskerk, PhD, Hendrik Veelken, MD PhD, Marcelo A Navarrete, MD PhD

Blood (2016) 128 (22): 914.

https://doi.org/10.1182/blood.V128.22.914.914

Published: 2016

Journal Articles

Whole Transcriptome Sequencing (RNAseq) As a Comprehensive, Cost-Efficient Diagnostic Tool for Acute Myeloid Leukemia

Marieke Griffioen, PhD, Wibowo Arindrarto, MSc, Daniel Borràs, MSc, Saskia A.M.E. van Diessen, BSc, Edith D. van der Meijden, M. Willy Honders, Mariam Alloul, PhD, Inge Jedema, PhD, Wilma G.M. Kroes, PhD, Peter J.M. Valk, PhD, Bart Janssen, PhD, Cornelis A.M. van Bergen, PhD, Szymon M. Kiełbasa, PhD, Jeroen F.J. Laros, PhD, Peter A.C. 't Hoen, PhD, Hendrik Veelken, MD PhD

Blood (2016) 128 (22): 1701.

https://doi.org/10.1182/blood.V128.22.1701.1701

Published: 2016

Journal Articles

Antigen-Independent, Autonomous B-Cell Receptor Signaling As a Dominant Candidate Oncogenic Mechanism in ABC DLBCL

Marvyn T. Koning, BSc, Rudolf Übelhart, PhD, Arjen H.G. Cleven, PhD, Willem H. Zoutman, BSc, Sander A.J. van der Zeeuw, BSc, Philip Kluin, MD PhD, Marieke Griffioen, PhD, Cornelis P. Tensen, PhD, Maarten H. Vermeer, MD PhD, Rein Willemze, MD PhD, Szymon M. Kielbasa, PhD, Marcelo A. Navarrete, MD PhD, Hassan Jumaa, PhD, Hendrik Veelken, MD PhD

Blood (2016) 128 (22): 778.

https://doi.org/10.1182/blood.V128.22.778.778

Published: 2016

Journal Articles

Indirect Presentation of Y-Chromosome Antigen Dby Is Regulated By Hsc70 and Mediated through CD63 Positive Exosomes

Sascha Kretschmann, Heiko Bruns, PhD, Ursula Schlötzer-Schrehardt, PhD, Andreas Mackensen, MD, Marieke Griffioen, PhD, Anita Kremer

Blood (2016) 128 (22): 3712.

https://doi.org/10.1182/blood.V128.22.3712.3712

Published: 2016

Journal Articles

Massive Parallel Sequencing of Full-Length B-Cell Receptor Sequences Reveals HLA-Dependent Shaping of the B-Cell Immune Repertoire

Marvyn T. Koning, Sander A.J. van der Zeeuw, Marcelo Navarrete, MD, Cornelis A.M. van Bergen, Valeri Nteleah, MSc, Marieke Griffioen, PhD, Szymon M. Kiełbasa, PhD, Hendrik Veelken, MDPhD

Blood (2014) 124 (21): 4143.

https://doi.org/10.1182/blood.V124.21.4143.4143

Published: 2014

Journal Articles

Graft Versus Leukemia Separates From Graft Versus Host Disease By Magnitude and Avidity Of The Allo-Reactive T Cell Response After Allogeneic Stem Cell Transplantation and Donor Lymphocyte Infusion

Cornelis A.M. van Bergen, Simone A.P. Van Luxemburg-Heijs, Matthijs Eefting, MD, Maria W. Honders, Inge Jedema, PhD, Constantijn J.M. Halkes, MD, PhD, Marieke Griffioen, PhD, J.H. Frederik Falkenburg, MD, PhD

Blood (2013) 122 (21): 2014.

https://doi.org/10.1182/blood.V122.21.2014.2014

Published: 2013

Journal Articles

LB-ARHGDIB-1R As Novel Minor Histocompatibility Antigen For Therapeutic Application

Margot J Pont, Willemijn Hobo, PhD, M. Willy Honders, Simone A.P. van Luxemburg-Heijs, Michel G.D. Kester, Cornelis A.M. van Bergen, Harry Dolstra, PhD, J.H. Frederik Falkenburg, MD, PhD, Marieke Griffioen, PhD

Blood (2013) 122 (21): 4465.

https://doi.org/10.1182/blood.V122.21.4465.4465

Published: 2013

Journal Articles

Durable Remission of Renal Cell Carcinoma After Donor Lymphocyte Infusion Is Unavoidably Linked with Graft Versus Host Disease As Illustrated by the Detection of Allo Reactive T Cells Recognizing a Novel Minor Histocompatibility Antigen Encoded by the FUCA2 Gene

Cornelis A.M. van Bergen, Elizabeth M.E. Verdegaal, PhD, Conny Hoogstraten, A.Q.M. Jeanne van Steijn, Linda de Quartel, Joan H. de Jong, Maaike Meyering, Marieke Griffioen, PhD, J.H.Frederik Falkenburg, MD, PhD, Susanne Osanto, MD, PhD

Blood (2012) 120 (21): 4467.

https://doi.org/10.1182/blood.V120.21.4467.4467

Published: 2012

Journal Articles

HLA Class II Disparity Is Necessary and Sufficient for Induction of Effective Anti-Tumor Immunity by Donor Lymphocyte Infusion in a NOD/Scid Mouse Model for Human Acute Lymphoblastic Leukemia

Sanja Stevanovic, MSc, Marianke L.J. van Schie, Marieke Griffioen, PhD, J.H. Frederik Falkenburg, MD, PhD

Blood (2011) 118 (21): 648.

https://doi.org/10.1182/blood.V118.21.648.648

Published: 2011

Journal Articles

High Throughput Screening for Antibody Responses Against H-Y Antigens and Their X-Variants in Allogeneic Hematopoeietic Stem Cell Transplantation,

Judith C van der Griendt, MSc, Edith D van der Meijden, Burcu Ayoglu, Jochen M Schwenk, Peter Nilsson, J.H. Frederik Falkenburg, MD, PhD, Marieke Griffioen, PhD

Blood (2011) 118 (21): 4097.

https://doi.org/10.1182/blood.V118.21.4097.4097

Published: 2011

Journal Articles

HLA Class II Upregulation During An Ongoing Viral Infection Can Lead to HLA-DP Directed Graft-Versus-Host Disease After HLA-DPB1 Mismatched CD4+ Donor Lymphocyte Infusion

Sanja Stevanovic, MSc, Cornelis A.M. van Bergen, Simone A.P. van Luxemburg-Heijs, Jessica C. Harskamp, MD, C.J.M. Halkes, MD, PhD, Marieke Griffioen, PhD, J.H. Frederik Falkenburg, MD, PhD

Blood (2011) 118 (21): 3062.

https://doi.org/10.1182/blood.V118.21.3062.3062

Published: 2011

Journal Articles

Primary Antibody Responses Against the Novel Pandemic H1N1 and Secondary Antibody Responses Against Seasonal H1N1 Can Be Induced by Vaccination In Patients Early After Allogeneic Stem Cell Transplantation

Roselke E Klinkenberg, MD, Marieke Griffioen, PhD, Edith D van der Meijden, Erik W.A. Marijt, MD, PhD, J.H. Frederik Falkenburg, MD, PhD

Blood (2010) 116 (21): 1273.

https://doi.org/10.1182/blood.V116.21.1273.1273

Published: 2010

Journal Articles

High Avidity PRAME Specific T Cells Derived From In Vivo HLA Mismatched Transplantation Setting Potentially Useful for Immunotherapeutic Strategies.

Avital L. Amir, MD, Dirk M. van der Steen, Renate S. Hagedoorn, Marieke Griffioen, PhD, J.H. Frederik Falkenburg, MD, PhD, Mirjam H.M. Heemskerk, PhD

Blood (2009) 114 (22): 4087.

https://doi.org/10.1182/blood.V114.22.4087.4087

Published: 2009

Journal Articles

Human T Cells with Distinct Specificities Mediate Graft-Versus-Leukemia Reactivity and Xenogeneic Graft-Versus-Host Disease in a NOD/Scid Mouse Model for Human Acute Leukemia.

Sanja Stevanovic, Bart Nijmeijer, PhD, Marianke LJ Van Schie, Roelof Willemze, MD, PhD, Marieke Griffioen, PhD, J.H. Frederik Falkenburg, MD, PhD

Blood (2009) 114 (22): 1330.

https://doi.org/10.1182/blood.V114.22.1330.1330

Published: 2009

Journal Articles

Identification of Four New HLA Class II Restricted Minor Histocompatibility Antigens Contributing to Graft Versus Leukemia Reactivity.

Anita N. Stumpf, Edith D. van der Meijden, Cornelis A.M. van Bergen, Roelof Willemze, MD, PhD, J.H. Frederik Falkenburg, MD, PhD, Marieke Griffioen, PhD

Blood (2008) 112 (11): 3247.

https://doi.org/10.1182/blood.V112.11.3247.3247

Published: 2008

NARROW

HLA-DM Mediates Permissiveness of HLA-DPB1 T Cell Epitope Mismatches in Unrelated HCT

Whole Transcriptome RNA Sequencing As a Comprehensive Diagnostic Tool for Acute Myeloid Leukemia

Fusion Transcripts without Corresponding Cytogenetic Abnormalities in Acute Myeloid Leukemia: Implications for AML Pathogenesis

Mutated NPM1 As Target for Immunotherapy of Acute Myeloid Leukemia

Primary Mediastinal Large B-Cell Lymphoma Exhibits Autonomous BCR Signaling and Responds to the Second Generation BTK Inhibitor Acalabrutinib

Endogenous Immunoglobulin-Derived Neoepitopes Are Processed and Form a Sizeable Fraction of the HLA Class I Ligandome of Human Lymphoma Cells

Whole Transcriptome Sequencing (RNAseq) As a Comprehensive, Cost-Efficient Diagnostic Tool for Acute Myeloid Leukemia

Antigen-Independent, Autonomous B-Cell Receptor Signaling As a Dominant Candidate Oncogenic Mechanism in ABC DLBCL

Indirect Presentation of Y-Chromosome Antigen Dby Is Regulated By Hsc70 and Mediated through CD63 Positive Exosomes

Massive Parallel Sequencing of Full-Length B-Cell Receptor Sequences Reveals HLA-Dependent Shaping of the B-Cell Immune Repertoire

Graft Versus Leukemia Separates From Graft Versus Host Disease By Magnitude and Avidity Of The Allo-Reactive T Cell Response After Allogeneic Stem Cell Transplantation and Donor Lymphocyte Infusion

LB-ARHGDIB-1R As Novel Minor Histocompatibility Antigen For Therapeutic Application

Durable Remission of Renal Cell Carcinoma After Donor Lymphocyte Infusion Is Unavoidably Linked with Graft Versus Host Disease As Illustrated by the Detection of Allo Reactive T Cells Recognizing a Novel Minor Histocompatibility Antigen Encoded by the FUCA2 Gene

HLA Class II Disparity Is Necessary and Sufficient for Induction of Effective Anti-Tumor Immunity by Donor Lymphocyte Infusion in a NOD/Scid Mouse Model for Human Acute Lymphoblastic Leukemia

High Throughput Screening for Antibody Responses Against H-Y Antigens and Their X-Variants in Allogeneic Hematopoeietic Stem Cell Transplantation,

HLA Class II Upregulation During An Ongoing Viral Infection Can Lead to HLA-DP Directed Graft-Versus-Host Disease After HLA-DPB1 Mismatched CD4+ Donor Lymphocyte Infusion

Primary Antibody Responses Against the Novel Pandemic H1N1 and Secondary Antibody Responses Against Seasonal H1N1 Can Be Induced by Vaccination In Patients Early After Allogeneic Stem Cell Transplantation

High Avidity PRAME Specific T Cells Derived From In Vivo HLA Mismatched Transplantation Setting Potentially Useful for Immunotherapeutic Strategies.

Human T Cells with Distinct Specificities Mediate Graft-Versus-Leukemia Reactivity and Xenogeneic Graft-Versus-Host Disease in a NOD/Scid Mouse Model for Human Acute Leukemia.

Identification of Four New HLA Class II Restricted Minor Histocompatibility Antigens Contributing to Graft Versus Leukemia Reactivity.

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American Society of Hematology

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American Society of Hematology

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