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Martina Seiffert, PhD
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Journal Articles

Eomes and IL-10 Regulate Anti-Tumor Activity of T Cells in Chronic Lymphocytic Leukemia

Laura Llaó Cid, M.Sc, Philipp M Rößner, MD, Ekaterina Lupar, PhD, Bola S Hanna, PhD, Jérôme Paggetti, PhD, Etienne Moussay, PhD, Dolors Colomer, PhD, Sascha Dietrich, MD, Stephan Stilgenbauer, MD, Ana Izcue, PhD, Martina Seiffert, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4288.
https://doi.org/10.1182/blood-2019-128465
Published: 2019
Journal Articles

Targeting IRAK4 Disrupts Inflammatory Pathways and Delays Tumor Development in Chronic Lymphocytic Leukemia

Neus Giménez Carabaza, B.Pharm, Rosich Laia, PhD, Schulz Ralph, MS, Higashi Morihiro, MD, Marta Aymerich, Neus Villamor, PhD, Julio Delgado, MD, Manel Juan, MD, Monica Lopez-Guerra, PhD, Elias Campo, Martina Seiffert, PhD, Dolors Colomer, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2650.
https://doi.org/10.1182/blood-2018-99-115999
Published: 2018
Journal Articles

CLL Exosome-Derived Y RNA hY4 Induces TLR7/8-Mediated Inflammation and PD-L1 Expression in Monocytes

Franziska Haderk, MSc, Laura Llao Cid, MSc, Murat Iskar, PhD, Ralph Schulz, MSc, Maria Goebel, MD, Jan Duerig, MD, Stephan Stilgenbauer, Marc Zapatka, Peter Lichter, PhD, Martina Seiffert, PhD
Journal: Blood
Blood (2016) 128 (22): 3217.
https://doi.org/10.1182/blood.V128.22.3217.3217
Published: 2016
Journal Articles

Immune Checkpoint Blockade with Anti-PD-L1 Prevents Immune Dysfuntion and CLL Development in the TCL1 Adoptive Transfer Mouse Model

Bola Hanna, Fabienne McClanahan, MD, Andrew James Clear, BSc, Shaun Miller, Peter Lichter, PhD, Martina Seiffert, PhD, John G. Gribben, MD DSc
Journal: Blood
Blood (2014) 124 (21): 717.
https://doi.org/10.1182/blood.V124.21.717.717
Published: 2014
Journal Articles

The Flavonoid Wogonin Reduces CLL Cell Survival in Vitro and Leukemia Development in Eµ-TCL1 Mice By Targeting Aberrant TNF Receptor Signaling

Claudia Dürr, Bola Hanna, Fabienne McClanahan, MD, Andrew James Clear, BSc, Thorsten Zenz, MD, Stephan Stilgenbauer, MD, John G. Gribben, MD DSc, Peter Lichter, PhD, Martina Seiffert, PhD
Journal: Blood
Blood (2014) 124 (21): 1966.
https://doi.org/10.1182/blood.V124.21.1966.1966
Published: 2014
Journal Articles

Chronic Lymphocytic Leukemia-Derived Extracellular Vesicles Contain a Distinctive Proteome, As Well As Specific Micro RNAs and Y RNAs

Franziska Haderk, Etienne Moussay, Jerome Paggetti, Maria Göbel, Jan Dürig, MD, Thorsten Zenz, MD, Stephan Stilgenbauer, MD, Peter Lichter, PhD, Martina Seiffert, PhD
Journal: Blood
Blood (2014) 124 (21): 1968.
https://doi.org/10.1182/blood.V124.21.1968.1968
Published: 2014
Journal Articles

Targeting Dysfunctional Myeloid Cells Delays Disease Development and Improves Immune Function in a CLL Mouse Model

Bola Hanna, Fabienne McClanahan, MD, Nadja Zaborsky, PhD, Claudia Dürr, Verena Kalter, Alexander Egle, MD, John G. Gribben, MD DSc, Peter Lichter, PhD, Martina Seiffert, PhD
Journal: Blood
Blood (2014) 124 (21): 3298.
https://doi.org/10.1182/blood.V124.21.3298.3298
Published: 2014
Journal Articles

Microenvironmental Factors and The Role Of Tumor Necrosis Factor Receptor Type 1 (TNFR-1) In Chronic Lymphocytic Leukemia

Claudia Duerr, Angela Schulz, PhD, Sibylle Ohl, Thorsten Zenz, MD, Stephan Stilgenbauer, MD, Peter Lichter, PhD, Martina Seiffert, PhD
Journal: Blood
Blood (2013) 122 (21): 4149.
https://doi.org/10.1182/blood.V122.21.4149.4149
Published: 2013
Journal Articles

Systematic Mapping Of Drug and Pathway Sensitivity In Chronic Lymphocytic Leukemia Identifies Synthetic Lethal Interactions Of Mutant p53

Leopold Sellner, MD, Oles Malgorzata, Mikolaj Slabicki, PhD, Carolin Blume, Hüllein Jennifer, Tatjana Stolz, Martin Sill, PhD, Sascha Dietrich, MD, Olaf Merkel, PhD, Anna Jauch, PhD, Manfred Hensel, MD, Davide Rossi, Zirlik Katja, MD, Martina Seiffert, PhD, Anthony D. Ho, MD, von Kalle Christof, MD, Hanno Glimm, MD, Wolfgang Huber, PhD, Thorsten Zenz, MD
Journal: Blood
Blood (2013) 122 (21): 173.
https://doi.org/10.1182/blood.V122.21.173.173
Published: 2013
Journal Articles

Lenalidomide Reduces Survival of Chronic Lymphocytic Leukemia Cells in Primary Co-Cultures by Altering the Myeloid Microenvironment

Angela Schulz, PhD, Claudia Dürr, Thorsten Zenz, MD, Stephan Stilgenbauer, MD, Peter Lichter, PhD, Martina Seiffert, PhD
Journal: Blood
Blood (2012) 120 (21): 3894.
https://doi.org/10.1182/blood.V120.21.3894.3894
Published: 2012
Journal Articles

The Toll-Like Receptor-Like Molecule CD180 and Soluble CD14 Transmit Survival Signals in B-Cell Chronic Lymphocytic Leukemia Cells Presumably by Acting As Co-Receptors,

Martina Seiffert, PhD, Angela Schulz, PhD, Stephan Stilgenbauer, MD, Peter Lichter
Journal: Blood
Blood (2011) 118 (21): 3883.
https://doi.org/10.1182/blood.V118.21.3883.3883
Published: 2011
Journal Articles

MicroRNA-130a Targets ATG2B , AGO4 and DICER1 , Inhibits Autophagy and Induces Cell Death in Chronic Lymphocytic Leukemia

Valentina Kovaleva, Rodrigo Mora, PhD, Stephan Stilgenbauer, MD, Peter Lichter, Martina Seiffert, PhD
Journal: Blood
Blood (2011) 118 (21): 1768.
https://doi.org/10.1182/blood.V118.21.1768.1768
Published: 2011